| 1 | KLK14
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| The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
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| Kryza T, Bock N, Lovell S, Rockstroh A, Lehman ML, Lesner A, Panchadsaram J, Silva LM, Srinivasan S, Snell CE, Williams ED, Fazli L, Gleave M, Batra J, Nelson C, Tate EW, Harris J, Hooper JD, Clements JA.
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| Mol Oncol 14(1):105-128. doi: 10.1002/1878-0261.12587. Epub 2019 Nov 28.
2020
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| 2 | KLK14, KLK8, KLK9
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| LEKTI domains D6, D7 and D8+9 serve as substrates for transglutaminase 1: implications for targeted therapy of Netherton syndrome.
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| Wiegmann H, Valentin F, Tarinski T, Liebau E, Loser K, Traupe H, Oji V.
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| Br J Dermatol 181(5):999-1008. doi: 10.1111/bjd.17820. Epub 2019 Jun 6.
2019
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| 3 | KLK1, KLK10, KLK13, KLK14, KLK6
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| Functional interrelationships between the kallikrein-related peptidases family and the classical kinin system in the human neutrophil.
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| Ehrenfeld P, Bhoola KD, Matus CE, Figueroa CD.
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| Biol Chem 399(9):925-935. doi: 10.1515/hsz-2017-0338. Review.
2018
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| 4 | KLK13, KLK14
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| Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
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| Dettmar L, Ahmed N, Kotzsch M, Diersch S, Napieralski R, Darmoul D, Schmitt M, Weichert W, Kiechle M, Dorn J, Magdolen V.
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| J Cancer Res Clin Oncol 144(6):1109-1118. doi: 10.1007/s00432-018-2623-7. Epub 2018 Mar 15.
2018
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| 5 | KLK14, KLK5, KLK7, SERPINA12
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| Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
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| Ulbricht D, Tindall CA, Oertwig K, Hanke S, Sträter N, Heiker JT.
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| Biol Chem 399(9):1079-1084. doi: 10.1515/hsz-2018-0108.
2018
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| 6 | HPN, KLK14, KLK4, MMP3, TMPRSS2
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| Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
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| Reid JC, Matsika A, Davies CM, He Y, Broomfield A, Bennett NC, Magdolen V, Srinivasan B, Clements JA, Hooper JD.
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| Am J Cancer Res 7(11):2257-2274. eCollection 2017.
2017
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| 7 | KLK14, KLK5, KLK7
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| Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum.
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| de Veer SJ, Furio L, Swedberg JE, Munro CA, Brattsand M, Clements JA, Hovnanian A, Harris JM.
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| J Invest Dermatol 137(2):430-439. doi: 10.1016/j.jid.2016.09.017. Epub 2016 Sep 30.
2017
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| 8 | KLK14
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| In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.
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| Reid JC, Bennett NC, Stephens CR, Carroll ML, Magdolen V, Clements JA, Hooper JD.
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| Biol Chem 397(12):1299-1305. doi: 10.1515/hsz-2016-0163.
2016
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| 9 | KLK14, KLK7
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| Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7KLK14) in colon cancer.
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| Devetzi M, Trangas T, Scorilas A, Xynopoulos D, Talieri M.
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| Thromb Haemost 109(4):716-25. doi: 10.1160/TH12-07-0518. Epub 2012 Dec 6.
2013
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| 10 | F2RL1, KLK14
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| Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors.
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| Chung H, Hamza M, Oikonomopoulou K, Gratio V, Saifeddine M, Virca GD, Diamandis EP, Hollenberg MD, Darmoul D.
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| Biol Chem 393(5):413-20. doi: 10.1515/bc-2011-231.
2012
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| 11 | KLK14
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| Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
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| Papachristopoulou G, Avgeris M, Charlaftis A, Scorilas A.
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| Thromb Haemost 105(1):131-7. doi: 10.1160/TH10-02-0092. Epub 2010 Nov 5.
2011
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| 12 | KLK14
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| Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
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| Papachristopoulou G, Avgeris M, Charlaftis A, Scorilas A.
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| Thromb Haemost 105(1). [Epub ahead of print]PMID: 21057706 2010
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| 13 | KLK14
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| Human kallikrein 14 (KLK14) expression in salivary gland tumors.
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| Hashem NN, Mara TW, Mohamed M, Zhang I, Fung K, Kwan KF, Daley TD, Diamandis EP, Darling MR.
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| Int J Biol Markers 25(1):32-7.PMID: 20155713 2010
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| 14 | KLK1, KLK13, KLK14, KLK2, KLK5, KLK6
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| Association between kallikrein-related peptidases (KLKs) and macroscopic indicators of semen analysis: their relation to sperm motility.
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| Emami N, Scorilas A, Soosaipillai A, Earle T, Mullen B, Diamandis EP.
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| Biol Chem 390(9):921-9.PMID: 19558318 2009
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| 15 | KLK14
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| Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skin.
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| Emami N, Diamandis EP.
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| J Biol Chem 283(6):3031-41. Epub 2007 Dec 3. 2008
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| 16 | KLK14, SEMG1, SEMG2
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| Major role of human KLK14 in seminal clot liquefaction.
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| Emami N, Deperthes D, Malm J, Diamandis EP.
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| J Biol Chem 283(28):19561-9. Epub 2008 May 15. 2008
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| 17 | KLK10, KLK11, KLK14
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| Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor.
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| Paliouras M, Diamandis EP.
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| Mol Oncol 1(4):413-24. Epub 2008 Jan 9.PMID: 19383315 2008
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| 18 | KLK13, KLK14
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| Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung.
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| Planque C, Bléchet C, Ayadi-Kaddour A, Heuzé-Vourc'h N, Dumont P, Guyétant S, Diamandis EP, El Mezni F, Courty Y.
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| Biol Chem 389(6):781-6.PMID: 18627302 2008
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| 19 | KLK10, KLK11, KLK14, KLK3
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| Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
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| Paliouras M, Diamandis EP.
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| Tumour Biol 29(2):63-75. Epub 2008 Jun 2.PMID: 18515984 2008
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| 20 | KLK1, KLK11, KLK14, KLK3
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| Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skin.
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| Emami N, Diamandis EP.
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| J Biol Chem 283(6):3031-41. Epub 2007 Dec 3.PMID: 18056261 2008
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| 21 | KLK1, KLK5, KLK6, KLK13, KLK14
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| A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation.
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| Borgono CA, Michael IP, Komatsu N, Jayakumar A, Kapadia R, Clayman GL, Sotiropoulou G, Diamandis EP.
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| J Biol Chem 282(6):3640-52. Epub 2006 Dec 11. 2007
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| 22 | KLK14
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| Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14.
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| Borgono CA, Michael IP, Shaw JL, Luo LY, Ghosh MC, Soosaipillai A, Grass L, Katsaros D, Diamandis EP.
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| J Biol Chem 282(4):2405-22. Epub 2006 Nov 16. 2007
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| 23 | KLK5, KLK7, KLK14
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| Kallikrein-related peptidase 14 may be a major contributor to trypsin-like proteolytic activity in human stratum corneum.
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| Stefansson K, Brattsand M, Ny A, Glas B, Egelrud T.
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| Biol Chem 387(6):761-8. 2006
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| 24 | KLK14
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| Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status.
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| Fritzsche F, Gansukh T, Borgono CA, Burkhardt M, Pahl S, Mayordomo E, Winzer KJ, Weichert W, Denkert C, Jung K, Stephan C, Dietel M, Diamandis EP, Dahl E, Kristiansen G.
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| Br J Cancer 94(4):540-7. 2006
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| 25 | KLK14
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| Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle.
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| Hooper JD, Bui LT, Rae FK, Harvey TJ, Myers SA, Ashworth LK, Clements JA.
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| Genomics 73(1):117-22. 2001
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| 26 | KLK14
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| Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies.
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| Yousef GM, Magklara A, Chang A, Jung K, Katsaros D, Diamandis EP.
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| Cancer Res 61(8):3425-31. 2001
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| 27 | KLK10, KLK11, KLK12, KLK13, KLK14, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| The New Human Kallikrein Gene Family: Implications in Carcinogenesis.
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| Diamandis EP, Yousef GM, Luo I, Magklara I, Obiezu CV.
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| Trends Endocrinol Metab 11(2):54-60. 2000
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| 28 | KLK12, KLK13, KLK14, KLK6
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| Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues.
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| Yousef GM, Chang A, Diamandis EP.
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| J Biol Chem 275(16):11891-8. 2000
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