1 | KLK11
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| KLK11 suppresses cellular proliferation via inhibition of Wnt/β-catenin signaling pathway in esophageal squamous cell carcinoma.
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| He X, Meng F, Qin L, Liu Z, Zhu X, Yu Z, Zheng Y.
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| Am J Cancer Res 9(10):2264-2277. eCollection 2019.
2019
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2 | KLK10, KLK11
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| Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
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| Geng X, Liu Y, Dreyer T, Bronger H, Drecoll E, Magdolen V, Dorn J.
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| Am J Cancer Res 8(9):1856-1864. eCollection 2018.
2018
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3 | KLK11, kLK12
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| Novel splice variants of the human kallikrein-related peptidases 11 (KLK11) and 12 (KLK12), unraveled by next-generation sequencing technology.
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| Adamopoulos PG, Kontos CK, Scorilas A.
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| Biol Chem 399(9):1065-1071. doi: 10.1515/hsz-2017-0294.
2018
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4 | KLK2, KLK3, KLK4, kLK11
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| Activation and activity of glycosylated KLKs 3, 4 and 11.
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| Guo S, Briza P, Magdolen V, Brandstetter H, Goettig P.
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| Biol Chem 399(9):1009-1022. doi: 10.1515/hsz-2018-0148.
2018
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5 | KLK11, KLK9
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| Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.
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| Geng X, Liu Y, Diersch S, Kotzsch M, Grill S, Weichert W, Kiechle M, Magdolen V, Dorn J.
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| PLoS One 12(11):e0186847. doi: 10.1371/journal.pone.0186847. eCollection 2017.
2017
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6 | KLK11
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| Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
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| Kolin DL, Sy K, Rotondo F, Bassily MN, Kovacs K, Brezden-Masley C, Streutker CJ, Yousef GM.
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| Tumour Biol 37(1):437-46. doi: 10.1007/s13277-015-3802-7. Epub 2015 Jul 30.
2016
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7 | BDRKB1, KLK1, KLK11, kLK6
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| Bioregulation of kallikrein-related peptidases 6, 10 and 11 by the kinin B₁ receptor in breast cancer cells.
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| Ehrenfeld P, Manso L, Pavicic MF, Matus CE, Borquez C, Lizama A, Sarmiento J, Poblete MT, Bhoola KD, Naran A, Figueroa CD.
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| Anticancer Res 34(12):6925-38.
2014
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8 | KLK11
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| KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.
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| Alexopoulou DK, Kontos CK, Christodoulou S, Papadopoulos IN, Scorilas A.
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| Biomark Med 8(5):671-85. doi: 10.2217/bmm.13.151.
2014
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9 | KLK11
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| Diagnostic and prognostic significance of human kallikrein 11 (KLK11) mRNA expression levels in patients with laryngeal cancer.
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| Patsis C, Yiotakis I, Scorilas A.
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| Clin Biochem 45(9):623-30. doi: 10.1016/j.clinbiochem.2012.03.005. Epub 2012 Mar 11.
2012
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10 | KLK11, KLK7
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| Immunohistochemical localization and analysis of kallikrein-related peptidase 7 and 11 expression in paired cancer and benign foci in prostate cancer patients.
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| Jamaspishvili T, Scorilas A, Kral M, Khomeriki I, Kurfurstova D, Kolar Z, Bouchal J.
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| Neoplasma 58(4):298-303.
2011
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11 | KLK11, TMPRSS2
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| Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer.
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| Bi X, He H, Ye Y, Dai Q, Han Z, Liang Y, Zhong W.
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| Med Oncol 27(1):145-51. Epub 2009 Feb 26.PMID: 19242826 2010
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12 | KLK10, KLK11, KLK14
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| Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor.
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| Paliouras M, Diamandis EP.
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| Mol Oncol 1(4):413-24. Epub 2008 Jan 9.PMID: 19383315 2008
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13 | KLK10, KLK11, KLK14, KLK3
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| Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
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| Paliouras M, Diamandis EP.
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| Tumour Biol 29(2):63-75. Epub 2008 Jun 2.PMID: 18515984 2008
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14 | KLK1, KLK11, KLK14, KLK3
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| Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skin.
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| Emami N, Diamandis EP.
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| J Biol Chem 283(6):3031-41. Epub 2007 Dec 3.PMID: 18056261 2008
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15 | KLK11
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| Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3.
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| Sano A, Sangai T, Maeda H, Nakamura M, Hasebe T, Ochiai A.
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| Int J Oncol 30(6):1493-8.PMID: 17487371 2007
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16 | KLK11
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| Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11/hippostasin.
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| Mitsui S, Nakamura T, Okui A, Kominami K, Uemura H, Yamaguchi N.
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| FEBS J 273(16):3678-86. 2006
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17 | KLK10, KLK11
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| Expression of the human kallikrein genes 10 (KLK10) and 11 (KLK11) in cancerous and non-cancerous lung tissues.
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| Planque C, Ainciburu M, Heuze-Vourc'h N, Regina S, de Monte M, Courty Y.
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| Biol Chem 387(6):783-8. 2006
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18 | KLK11
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| Alternative splicing isoforms of hippostasin (PRSS20/KLK11) in prostate cancer cell lines.
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| Nakamura T, Mitsui S, Okui A, Kominami K, Nomoto T, Ukimura O, Kawauchi A, Miki T, Yamaguchi N.
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| Prostate 49(1):72-8. 2001
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19 | APOC-E@, APOC1, APOC4, APOE, KLK11, KLK8, NECTIN2
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| Analysis of Association at Single Nucleotide Polymorphisms in the APOE Region.
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| Martin ER, Gilbert JR, Lai EH, Riley J, Rogala AR, Slotterbeck BD, Sipe CA, Grubber JM, Warren LL, Conneally PM, Saunders AM, Schmechel DE, Purvis I, Pericak-Vance MA, Roses AD, Vance JM.
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| Genomics 63(1):7-12. 2000
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20 | KLK10, KLK11, KLK12, KLK13, KLK14, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| The New Human Kallikrein Gene Family: Implications in Carcinogenesis.
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| Diamandis EP, Yousef GM, Luo I, Magklara I, Obiezu CV.
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| Trends Endocrinol Metab 11(2):54-60. 2000
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21 | KLK1, KLK10, KLK11, KLK12, KLK13, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.
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| Harvey TJ, Hooper JD, Myers SA, Stephenson SA, Ashworth LK, Clements JA.
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| J Biol Chem 275(48):37397-406.
2000
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22 | KLK11
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| cDNA cloning and expression of a novel serine protease, TLSP.
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| Yoshida S, et al.
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| Biochim Biophys Acta 1399(2-3):225-8 1998
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