Citations for
1KIT, SOHLH1, STRA8
Stimulated by retinoic acid gene 8 (STRA8) interacts with the germ cell specific bHLH factor SOHLH1 and represses c-KIT expression in vitro
Desimio MG, Cesari E, Sorrenti M, De Felici M, Farini D
J Cell Mol Med. Jan;25(1):383-396. doi: 10.1111/jcmm.16087. Epub 2020 Nov 25. 2021
2FUBP1, KIT, RUNX1
Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation
Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, Troadec MB
Nucleic Acids Res. Nov 30;46(21):11214-11228. doi: 10.1093/nar/gky756. 2018
3KIT, SH3BP2
The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.
Ainsua-Enrich E, Serrano-Candelas E, Álvarez-Errico D, Picado C, Sayós J, Rivera J, Martín M.
J Immunol 194(9):4309-18. doi: 10.4049/jimmunol.1402887. Epub 2015 Mar 25. 2015
4HAP1, KIT
Postnatal loss of hap1 reduces hippocampal neurogenesis and causes adult depressive-like behavior in mice.
Xiang J, Yan S, Li SH, Li XJ.
PLoS Genet 11(4):e1005175. doi: 10.1371/journal.pgen.1005175. 2015
5KCNJ2, KIT
Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells.
Zhang YY, Li G, Che H, Sun HY, Xiao GS, Wang Y, Li GR.
PLoS One 10(9):e0138581. doi: 10.1371/journal.pone.0138581. eCollection 2015. 2015
6KIT
KIT signaling regulates primordial follicle formation in the neonatal mouse ovary.
Jones RL, Pepling ME.
Dev Biol 382(1):186-97. doi: 10.1016/j.ydbio.2013.06.030. Epub 2013 Jul 4. 2013
7KIT
Phosphorylation of the activation loop tyrosine 823 in c-Kit is crucial for cell survival and proliferation.
Agarwal S, Kazi JU, Rönnstrand L.
J Biol Chem 288(31):22460-8. doi: 10.1074/jbc.M113.474072. Epub 2013 Jun 26. 2013
8KIT
KIT GNNK splice variants: expression in systemic mastocytosis and influence on the activating potential of the D816V mutation in mast cells.
Chan EC, Bai Y, Bandara G, Simakova O, Brittain E, Scott L, Dyer KD, Klion AD, Maric I, Gilfillan AM, Metcalfe DD, Wilson TM.
Exp Hematol 41(10):870-881.e2. doi: 10.1016/j.exphem.2013.05.005. Epub 2013 Jun 4. 2013
9FMST, KIT
A c-kit mutation in exon 18 in familial mastocytosis.
Wöhrl S, Moritz KB, Bracher A, Fischer G, Stingl G, Loewe R.
J Invest Dermatol 133(3):839-41. doi: 10.1038/jid.2012.394. Epub 2012 Nov 29. No abstract available. 2013
10KIT, KRT19
Expression of CK19 and KIT in resectable pancreatic neuroendocrine tumors.
Han X, Zhao J, Ji Y, Xu X, Lou W.
Tumour Biol 34(5):2881-9. doi: 10.1007/s13277-013-0850-8. Epub 2013 May 19. 2013
11KIT, RAB27B
Rab27b regulates c-kit expression by controlling the secretion of stem cell factor.
Tanaka C, Kaji H, He J, Hazama R, Yokoyama K, Kinoshita E, Tsujioka T, Tohyama K, Yamamura H, Nishio H, Tohyama Y.
Biochem Biophys Res Commun 419(2):368-73. doi: 10.1016/j.bbrc.2012.02.030. Epub 2012 Feb 13. 2012
12KIT
c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.
Regan JL, Kendrick H, Magnay FA, Vafaizadeh V, Groner B, Smalley MJ.
Oncogene 31(7):869-83. doi: 10.1038/onc.2011.289. Epub 2011 Jul 18. 2012
13KIT
CD117(+) amniotic fluid stem cells: state of the art and future perspectives.
Cananzi M, De Coppi P.
Organogenesis 8(3):77-88. doi: 10.4161/org.22426. Epub 2012 Jul 1. Review. 2012
14KIT, KITLG
Involvement of stem cell factor and c-kit in corneal wound healing in mice.
Miyamoto K, Kobayashi T, Hayashi Y, Zhang Y, Hara Y, Higashine M, Shiraishi A, Ohashi Y.
Mol Vis 18:1505-15. Epub 2012 Jun 7. 2012
15KIT
Expression of proto-oncogene KIT is up-regulated in subset of human meningiomas.
Saini M, Jha AN, Abrari A, Ali S.
BMC Cancer 12:212. doi: 10.1186/1471-2407-12-212. 2012
16KIT, KITLG, RIN3
RIN3 is a negative regulator of mast cell responses to SCF.
Janson C, Kasahara N, Prendergast GC, Colicelli J.
PLoS One 7(11):e49615. doi: 10.1371/journal.pone.0049615. Epub 2012 Nov 20. 2012
17KIT
C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice.
Wang YY, Zhao LJ, Wu CF, Liu P, Shi L, Liang Y, Xiong SM, Mi JQ, Chen Z, Ren R, Chen SJ.
Proc Natl Acad Sci U S A 108(6):2450-5. Epub 2011 Jan 24. 2011
18KIT, MKI67, TP53
CD117, Ki-67, and p53 predict survival in neuroendocrine carcinomas, but not within the subgroup of small cell lung carcinoma.
Erler BS, Presby MM, Finch M, Hodges A, Horowitz K, Topilow AA, Matulewicz T.
Tumour Biol 32(1):107-11. Epub 2010 Nov 8. 2011
19KIT, MITF
KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation.
Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM.
Blood 117(13):3629-40. Epub 2011 Jan 27. 2011
20FES, KIT, KITLG
FES kinase participates in KIT-ligand induced chemotaxis.
Voisset E, Lopez S, Chaix A, Vita M, George C, Dubreuil P, De Sepulveda P.
Biochem Biophys Res Commun 393(1):174-8. Epub 2010 Feb 1. 2010
21KDR, KIT, PDGFRA
Amplification and overexpression of KIT, PDGFRA, and VEGFR2 in medulloblastomas and primitive neuroectodermal tumors.
Blom T, Roselli A, Häyry V, Tynninen O, Wartiovaara K, Korja M, Nordfors K, Haapasalo H, Nupponen NN.
J Neurooncol 97(2):217-24. Epub 2009 Sep 25.PMID: 19779861 2010
22ETV1, KIT
ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.
Chi P, Chen Y, Zhang L, Guo X, Wongvipat J, Shamu T, Fletcher JA, Dewell S, Maki RG, Zheng D, Antonescu CR, Allis CD, Sawyers CL.
Nature 467(7317):849-53. Epub 2010 Oct 3. 2010
23KIT, KITLG
Co-expression of KIT receptor and its ligand stem cell factor in Merkel cell carcinoma.
Krasagakis K, Kruger-Krasagakis S, Eberle J, Tsatsakis A, Tosca AD, Stathopoulos EN.
Dermatology 218(1):37-43. Epub 2008 Nov 12. 2009
24CD34, KIT, ZBTB16
PLZF-mediated control on c-kit expression in CD34(+) cells and early erythropoiesis.
Spinello I, Quaranta MT, Pasquini L, Pelosi E, Petrucci E, Pagliuca A, Castelli G, Mariani G, Diverio D, Foŕ R, Testa U, Labbaye C.
Oncogene 28(23):2276-88. doi: 10.1038/onc.2009.87. Epub 2009 May 4. 2009
25GAB2, KIT
Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.
Sun J, Pedersen M, Rönnstrand L.
J Biol Chem 283(41):27444-51. Epub 2008 Aug 11. 2008
26KIT
Analysis of c-KIT expression and KIT gene mutation in human mucosal melanomas.
Satzger I, Schaefer T, Kuettler U, Broecker V, Voelker B, Ostertag H, Kapp A, Gutzmer R.
Br J Cancer 99(12):2065-9. Epub 2008 Nov 18. 2008
27KIT
Characterization of c-kit (CD117) expression in human normal pituitary cells and pituitary adenomas.
La Rosa S, Uccella S, Dainese L, Marchet S, Placidi C, Vigetti D, Capella C.
Endocr Pathol 19(2):104-11. 2008
28KIT, KITLG
Association of genetic markers within the KIT and KITLG genes with human male infertility.
Galan JJ, De Felici M, Buch B, Rivero MC, Segura A, Royo JL, Cruz N, Real LM, Ruiz A.
Hum Reprod 21(12):3185-92. Epub 2006 Aug 11. 2006
29KIT, FMST, FGIST
Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis.
Hartmann K, Wardelmann E, Ma Y, Merkelbach-Bruse S, Preussner LM, Woolery C, Baldus SE, Heinicke T, Thiele J, Buettner R, Longley BJ.
Gastroenterology 129(3):1042-6. 2005
30KIT, FMST, FGIST
Novel c-KIT germline mutation in a family with gastrointestinal stromal tumors and cutaneous hyperpigmentation.
Carballo M, Roig I, Aguilar F, Pol MA, Gamundi MJ, Hernan I, Martinez-Gimeno M.
Am J Med Genet A 132(4):361-4. 2005
31KIT, PDGFRA
Mutational analysis of the c-KIT AND PDGFRalpha in a series of molecularly well-characterized synovial sarcomas.
Lopez-Guerrero JA, Navarro S, Noguera R, Carda C, Farinas SC, Pellin A, Llombart-Bosch A.
Diagn Mol Pathol 14(3):134-9. 2005
32KIT, FGIST, FMST
Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia.
Robson ME, Glogowski E, Sommer G, Antonescu CR, Nafa K, Maki RG, Ellis N, Besmer P, Brennan M, Offit K.
Clin Cancer Res 10(4):1250-4. 2004
33KIT, FLT3
Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias.
Care RS, Valk PJ, Goodeve AC, Abu-Duhier FM, Geertsma-Kleinekoort WM, Wilson GA, Gari MA, Peake IR, Lowenberg B, Reilly JT.
Br J Haematol 121(5):775-7. 2003
34ENC1, KIT
Molecular characterisation of soft tissue tumours: a gene expression study.
Nielsen TO, West RB, Linn SC, Alter O, Knowling MA, O'Connell JX, Zhu S, Fero M, Sherlock G, Pollack JR, Brown PO, Botstein D, van de Rijn M.
Lancet 359(9314):1301-7. 2002
35KIT
Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution.
Hornick JL, Fletcher CD.
Am J Clin Pathol 117(2):188-93. 2002
36KIT
Chromosomal aberrations in malignant gastrointestinal stromal tumors: correlation with c-KIT gene mutation.
Debiec-Rychter M, Lasota J, Sarlomo-Rikala M, Kordek R, Miettinen M.
Cancer Genet Cytogenet 128(1):24-30. 2001
37KIT, FMST, FGIST
Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa.
Beghini A, Tibiletti MG, Roversi G, Chiaravalli AM, Serio G, Capella C, Larizza L.
Cancer 92(3):657-62. 2001
38KIT, FMST
Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis.
Longley BJ, et al.
Proc Natl Acad Sci U S A 96 : 1609-1614. 1999
39KIT
Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas.
Lasota J, et al.
Am J Pathol 154(1):53-60. 1999
40KIT, PBT1
Piebaldism with deafness : molecular evidence for an expanded syndrome.
Spritz RA, Beighton P.
Am J Med Genet 75(1):101-3. 1998
41CDH1, CDKN1A, KIT, MMP2, TFAP2A
Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
Jean D, et al.
J Biol Chem 273 : 16501-16508. 1998
42KIT
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene.
Nishida T, Hirota S, Taniguchi M, Hashimoto K, Isozaki K, Nakamura H, Kanakura Y, Tanaka T, Takabayashi A, Matsuda H, Kitamura Y.
Nat Genet 19 : 323-324. 1998
43KIT, FMST
Clinical correlates of the presence of the Asp816Val c-kit mutation in the peripheral blood mononuclear cells of patients with mastocytosis.
Worobec AS, et al.
Cancer 83 : 2120-2129. 1998
44CSF1R, HMGXB3, KIT
Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.
Andre C, Hampe A, Lachaume P, Martin E, Wang XP, Manus V, Hu WX, Galibert F.
Genomics 39 : 216-226. 1997
45KIT, FMST
A new c-kit mutation in a case of aggressive mast cell disease.
Pignon JM, et al.
Br J Haematol 96 : 374-376. 1997
46KIT, FMST
Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis : establishment of clonality in a human mast cell neoplasm.
Longley BJ, et al.
Nat Genet 12 : 312-314. 1996
47KIT, PBT1
Mutations in the ligand-binding domain of the kit receptor : an uncommon site in human piebaldism.
Fleischman RA, et al.
J Invest Dermatol 107 : 703-706. 1996
48KIT, FMST
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.
Nagata H, Worobec AS, Oh CK, Chowdhury BA, Tannenbaum S, Suzuki Y, Metcalfe DD.
Proc Natl Acad Sci U S A 92 : 10560-10564. 1995
49PBT1, KIT
A 12-bp deletion (7818del12) in the c-kit protooncogene in a large Italian kindred with piebaldism.
Riva P, et al.
Hum Mutat 6 : 343-345. 1995
50PBT1, KIT
Human piebaldism : relationship between phenotype and site of kit gene mutation.
Ward KA, et al.
Br J Dermatol 132 : 929-935. 1995
51PBT1, KIT
Novel mutations and deletions of the KIT (Steel Factor Receptor) gene inhuman piebaldism.
Ezoe K, et al.
Am J Hum Genet 56 : 58-66. 1995
52PDGFRA, KDR, KIT, EPHA5
A YAC contig spanning a cluster of human type III receptor protein tyrosine kinase genes (PDGFRA-KIT-KDR) in chromosome segment 4q12.
Spritz RA, et al.
Genomics 22 : 431-436. 1994
53PBT1, KIT
A novel mutation in the c-KIT protooncogene in a family with piebaldism. (abstr)
Larizza L, et al.
Am J Hum Genet 55 : A228. 1994
54PBT1, KIT
A recurrent deletion in the KIT (mast/stem cell growth factor receptor) proto-oncogene is a frequent cause of human piebaldism.
Spritz RA, et al.
Hum Mol Genet 2 : 1499-1500. 1993
55KIT
Polymerase chain reaction detection of a novel human KIT (mast/stem cell growth factor receptor) gene polymorphism by single-strand conformation polymorphism analysis or by SmaI or BstNI cleavage.
Spritz RA, et al.
Hum Genet 92 : 208-209. 1993
56KIT, PTPN6
Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand.
Yi T, Ihle JN.
Mol Cell Biol 13(6):3350-8. 1993
57KIT
Genomic organization of the human c-kit gene : evolution of the receptor tyrosine kinase subclass III.
AndrŽ C, et al.
Oncogene 7 : 685-691. 1992
58KIT
Cloning and structural analysis of the human c-kit gene.
Vandenbark GR, et al.
Oncogene 7 : 1259-1266. 1992
59KIT, PBT1
Mutations of the KIT (mast/stem cell growth factor receptor) proto-oncogene account for a continuous range of phenotypes in human piebaldism.
Spritz RA, et al.
Am J Hum Genet 51 : 1058-1065. 1992
60KIT
Organization and nucleotide sequence of the human KIT (mast/stem cell growth factor receptor) proto-oncogene.
Giebel LB, et al.
Oncogene 7 : 2207-2217. 1992
61KIT
Expression of messenger RNA for kit-ligand in human placenta : localization by in situ hybridization and identification of alternatively spliced variants.
Sharkey A, et al.
Mol Endocrinol 6 : 1235-1241. 1992
62KIT
Expression of two types of kit ligand mRNAs in human tumor cells.
Toyota M, et al.
Int J Haematol 55 : 301-304. 1992
63KIT
TaqI RFLP at the c-kit oncogene locus (KIT).
Drachtman RA, et al.
Nucleic Acids Res 19 : 6975. 1991
64KIT
c-kit expression by CD34+ bone marrow progenitors and inhibition of response to recombinant human interleukin-3 following exposure to c-kit antisense oligonucleotides.
Catlett JP, et al.
Blood 78 : 3186-3191. 1991
65KITLG, KIT
Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer.
Hibi K, et al.
Oncogene 6 : 2291-2296. 1991
66KIT
Detecting high-resolution polymorphisms in human coding loci by combining PCR and single-strand conformation polymorphism (SSCP) analysis.
Poduslo SE, et al.
Am J Hum Genet 49 : 106-111. 1991
67KIT
An Sstl RFLP at the C-Kit oncogene locus (KIT).
Curtis D.
Nucleic Acids Res 19 : 1352. 1991
68KIT
Localization of the human c-kit protooncogene on the q11-q12 region of chromosome 4.
d'Auriol L, et al.
Hum Genet 78 : 374-376. 1988
69KIT
A HindIII RFLP demonstrated for the kit oncogene on chromosome 4.
Berdahl LD, et al.
Nucleic Acids Res 16 : 4740. 1988
70KIT
The oncogene c-KIT is located on human chromosome 4 and mouse chromosome 5.
Yang-Feng TL, et al.
(HGM9) Cytogenet Cell Genet 46 : 723. 1987
71KIT
Assignment of the human c-kit proto-oncogene to the q11-q12 region of chromosome 4, using in situ hybridization.
Mattei MG, et al.
(HGM9) Cytogenet Cell Genet 46 : 657. 1987