| 1 | KIT, SOHLH1, STRA8
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| Stimulated by retinoic acid gene 8 (STRA8) interacts with the germ cell specific bHLH factor SOHLH1 and represses c-KIT expression in vitro
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| Desimio MG, Cesari E, Sorrenti M, De Felici M, Farini D
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| J Cell Mol Med. Jan;25(1):383-396. doi: 10.1111/jcmm.16087. Epub 2020 Nov 25. 2021
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| 2 | FUBP1, KIT, RUNX1
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| Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation
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| Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, Troadec MB
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| Nucleic Acids Res. Nov 30;46(21):11214-11228. doi: 10.1093/nar/gky756. 2018
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| 3 | KIT, SH3BP2
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| The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.
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| Ainsua-Enrich E, Serrano-Candelas E, Álvarez-Errico D, Picado C, Sayós J, Rivera J, Martín M.
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| J Immunol 194(9):4309-18. doi: 10.4049/jimmunol.1402887. Epub 2015 Mar 25.
2015
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| 4 | HAP1, KIT
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| Postnatal loss of hap1 reduces hippocampal neurogenesis and causes adult depressive-like behavior in mice.
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| Xiang J, Yan S, Li SH, Li XJ.
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| PLoS Genet 11(4):e1005175. doi: 10.1371/journal.pgen.1005175.
2015
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| 5 | KCNJ2, KIT
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| Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells.
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| Zhang YY, Li G, Che H, Sun HY, Xiao GS, Wang Y, Li GR.
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| PLoS One 10(9):e0138581. doi: 10.1371/journal.pone.0138581. eCollection 2015.
2015
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| 6 | KIT
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| KIT signaling regulates primordial follicle formation in the neonatal mouse ovary.
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| Jones RL, Pepling ME.
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| Dev Biol 382(1):186-97. doi: 10.1016/j.ydbio.2013.06.030. Epub 2013 Jul 4.
2013
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| 7 | KIT
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| Phosphorylation of the activation loop tyrosine 823 in c-Kit is crucial for cell survival and proliferation.
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| Agarwal S, Kazi JU, Rönnstrand L.
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| J Biol Chem 288(31):22460-8. doi: 10.1074/jbc.M113.474072. Epub 2013 Jun 26.
2013
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| 8 | KIT
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| KIT GNNK splice variants: expression in systemic mastocytosis and influence on the activating potential of the D816V mutation in mast cells.
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| Chan EC, Bai Y, Bandara G, Simakova O, Brittain E, Scott L, Dyer KD, Klion AD, Maric I, Gilfillan AM, Metcalfe DD, Wilson TM.
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| Exp Hematol 41(10):870-881.e2. doi: 10.1016/j.exphem.2013.05.005. Epub 2013 Jun 4.
2013
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| 9 | FMST, KIT
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| A c-kit mutation in exon 18 in familial mastocytosis.
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| Wöhrl S, Moritz KB, Bracher A, Fischer G, Stingl G, Loewe R.
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| J Invest Dermatol 133(3):839-41. doi: 10.1038/jid.2012.394. Epub 2012 Nov 29. No abstract available.
2013
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| 10 | KIT, KRT19
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| Expression of CK19 and KIT in resectable pancreatic neuroendocrine tumors.
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| Han X, Zhao J, Ji Y, Xu X, Lou W.
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| Tumour Biol 34(5):2881-9. doi: 10.1007/s13277-013-0850-8. Epub 2013 May 19.
2013
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| 11 | KIT, RAB27B
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| Rab27b regulates c-kit expression by controlling the secretion of stem cell factor.
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| Tanaka C, Kaji H, He J, Hazama R, Yokoyama K, Kinoshita E, Tsujioka T, Tohyama K, Yamamura H, Nishio H, Tohyama Y.
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| Biochem Biophys Res Commun 419(2):368-73. doi: 10.1016/j.bbrc.2012.02.030. Epub 2012 Feb 13.
2012
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| 12 | KIT
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| c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.
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| Regan JL, Kendrick H, Magnay FA, Vafaizadeh V, Groner B, Smalley MJ.
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| Oncogene 31(7):869-83. doi: 10.1038/onc.2011.289. Epub 2011 Jul 18.
2012
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| 13 | KIT
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| CD117(+) amniotic fluid stem cells: state of the art and future perspectives.
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| Cananzi M, De Coppi P.
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| Organogenesis 8(3):77-88. doi: 10.4161/org.22426. Epub 2012 Jul 1. Review.
2012
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| 14 | KIT, KITLG
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| Involvement of stem cell factor and c-kit in corneal wound healing in mice.
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| Miyamoto K, Kobayashi T, Hayashi Y, Zhang Y, Hara Y, Higashine M, Shiraishi A, Ohashi Y.
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| Mol Vis 18:1505-15. Epub 2012 Jun 7.
2012
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| 15 | KIT
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| Expression of proto-oncogene KIT is up-regulated in subset of human meningiomas.
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| Saini M, Jha AN, Abrari A, Ali S.
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| BMC Cancer 12:212. doi: 10.1186/1471-2407-12-212.
2012
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| 16 | KIT, KITLG, RIN3
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| RIN3 is a negative regulator of mast cell responses to SCF.
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| Janson C, Kasahara N, Prendergast GC, Colicelli J.
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| PLoS One 7(11):e49615. doi: 10.1371/journal.pone.0049615. Epub 2012 Nov 20.
2012
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| 17 | KIT
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| C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice.
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| Wang YY, Zhao LJ, Wu CF, Liu P, Shi L, Liang Y, Xiong SM, Mi JQ, Chen Z, Ren R, Chen SJ.
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| Proc Natl Acad Sci U S A 108(6):2450-5. Epub 2011 Jan 24.
2011
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| 18 | KIT, MKI67, TP53
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| CD117, Ki-67, and p53 predict survival in neuroendocrine carcinomas, but not within the subgroup of small cell lung carcinoma.
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| Erler BS, Presby MM, Finch M, Hodges A, Horowitz K, Topilow AA, Matulewicz T.
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| Tumour Biol 32(1):107-11. Epub 2010 Nov 8.
2011
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| 19 | KIT, MITF
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| KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation.
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| Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM.
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| Blood 117(13):3629-40. Epub 2011 Jan 27.
2011
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| 20 | FES, KIT, KITLG
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| FES kinase participates in KIT-ligand induced chemotaxis.
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| Voisset E, Lopez S, Chaix A, Vita M, George C, Dubreuil P, De Sepulveda P.
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| Biochem Biophys Res Commun 393(1):174-8. Epub 2010 Feb 1.
2010
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| 21 | KDR, KIT, PDGFRA
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| Amplification and overexpression of KIT, PDGFRA, and VEGFR2 in medulloblastomas and primitive neuroectodermal tumors.
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| Blom T, Roselli A, Häyry V, Tynninen O, Wartiovaara K, Korja M, Nordfors K, Haapasalo H, Nupponen NN.
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| J Neurooncol 97(2):217-24. Epub 2009 Sep 25.PMID: 19779861 2010
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| 22 | ETV1, KIT
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| ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.
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| Chi P, Chen Y, Zhang L, Guo X, Wongvipat J, Shamu T, Fletcher JA, Dewell S, Maki RG, Zheng D, Antonescu CR, Allis CD, Sawyers CL.
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| Nature 467(7317):849-53. Epub 2010 Oct 3.
2010
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| 23 | KIT, KITLG
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| Co-expression of KIT receptor and its ligand stem cell factor in Merkel cell carcinoma.
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| Krasagakis K, Kruger-Krasagakis S, Eberle J, Tsatsakis A, Tosca AD, Stathopoulos EN.
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| Dermatology 218(1):37-43. Epub 2008 Nov 12.
2009
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| 24 | CD34, KIT, ZBTB16
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| PLZF-mediated control on c-kit expression in CD34(+) cells and early erythropoiesis.
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| Spinello I, Quaranta MT, Pasquini L, Pelosi E, Petrucci E, Pagliuca A, Castelli G, Mariani G, Diverio D, Foà R, Testa U, Labbaye C.
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| Oncogene 28(23):2276-88. doi: 10.1038/onc.2009.87. Epub 2009 May 4.
2009
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| 25 | GAB2, KIT
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| Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.
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| Sun J, Pedersen M, Rönnstrand L.
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| J Biol Chem 283(41):27444-51. Epub 2008 Aug 11.
2008
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| 26 | KIT
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| Analysis of c-KIT expression and KIT gene mutation in human mucosal melanomas.
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| Satzger I, Schaefer T, Kuettler U, Broecker V, Voelker B, Ostertag H, Kapp A, Gutzmer R.
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| Br J Cancer 99(12):2065-9. Epub 2008 Nov 18.
2008
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| 27 | KIT
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| Characterization of c-kit (CD117) expression in human normal pituitary cells and pituitary adenomas.
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| La Rosa S, Uccella S, Dainese L, Marchet S, Placidi C, Vigetti D, Capella C.
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| Endocr Pathol 19(2):104-11.
2008
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| 28 | KIT, KITLG
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| Association of genetic markers within the KIT and KITLG genes with human male infertility.
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| Galan JJ, De Felici M, Buch B, Rivero MC, Segura A, Royo JL, Cruz N, Real LM, Ruiz A.
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| Hum Reprod 21(12):3185-92. Epub 2006 Aug 11.
2006
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| 29 | KIT, FMST, FGIST
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| Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis.
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| Hartmann K, Wardelmann E, Ma Y, Merkelbach-Bruse S, Preussner LM, Woolery C, Baldus SE, Heinicke T, Thiele J, Buettner R, Longley BJ.
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| Gastroenterology 129(3):1042-6. 2005
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| 30 | KIT, FMST, FGIST
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| Novel c-KIT germline mutation in a family with gastrointestinal stromal tumors and cutaneous hyperpigmentation.
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| Carballo M, Roig I, Aguilar F, Pol MA, Gamundi MJ, Hernan I, Martinez-Gimeno M.
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| Am J Med Genet A 132(4):361-4. 2005
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| 31 | KIT, PDGFRA
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| Mutational analysis of the c-KIT AND PDGFRalpha in a series of molecularly well-characterized synovial sarcomas.
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| Lopez-Guerrero JA, Navarro S, Noguera R, Carda C, Farinas SC, Pellin A, Llombart-Bosch A.
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| Diagn Mol Pathol 14(3):134-9. 2005
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| 32 | KIT, FGIST, FMST
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| Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia.
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| Robson ME, Glogowski E, Sommer G, Antonescu CR, Nafa K, Maki RG, Ellis N, Besmer P, Brennan M, Offit K.
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| Clin Cancer Res 10(4):1250-4. 2004
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| 33 | KIT, FLT3
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| Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias.
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| Care RS, Valk PJ, Goodeve AC, Abu-Duhier FM, Geertsma-Kleinekoort WM, Wilson GA, Gari MA, Peake IR, Lowenberg B, Reilly JT.
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| Br J Haematol 121(5):775-7. 2003
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| 34 | ENC1, KIT
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| Molecular characterisation of soft tissue tumours: a gene expression study.
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| Nielsen TO, West RB, Linn SC, Alter O, Knowling MA, O'Connell JX, Zhu S, Fero M, Sherlock G, Pollack JR, Brown PO, Botstein D, van de Rijn M.
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| Lancet 359(9314):1301-7. 2002
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| 35 | KIT
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| Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution.
|
| Hornick JL, Fletcher CD.
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| Am J Clin Pathol 117(2):188-93. 2002
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| 36 | KIT
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| Chromosomal aberrations in malignant gastrointestinal stromal tumors: correlation with c-KIT gene mutation.
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| Debiec-Rychter M, Lasota J, Sarlomo-Rikala M, Kordek R, Miettinen M.
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| Cancer Genet Cytogenet 128(1):24-30. 2001
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| 37 | KIT, FMST, FGIST
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| Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa.
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| Beghini A, Tibiletti MG, Roversi G, Chiaravalli AM, Serio G, Capella C, Larizza L.
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| Cancer 92(3):657-62. 2001
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| 38 | KIT, FMST
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| Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis.
|
| Longley BJ, et al.
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| Proc Natl Acad Sci U S A 96 : 1609-1614. 1999
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| 39 | KIT
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| Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas.
|
| Lasota J, et al.
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| Am J Pathol 154(1):53-60. 1999
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| 40 | KIT, PBT1
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| Piebaldism with deafness : molecular evidence for an expanded syndrome.
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| Spritz RA, Beighton P.
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| Am J Med Genet 75(1):101-3. 1998
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| 41 | CDH1, CDKN1A, KIT, MMP2, TFAP2A
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| Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
|
| Jean D, et al.
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| J Biol Chem 273 : 16501-16508. 1998
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| 42 | KIT
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| Familial gastrointestinal stromal tumours with germline mutation of the KIT gene.
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| Nishida T, Hirota S, Taniguchi M, Hashimoto K, Isozaki K, Nakamura H, Kanakura Y, Tanaka T, Takabayashi A, Matsuda H, Kitamura Y.
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| Nat Genet 19 : 323-324. 1998
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| 43 | KIT, FMST
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| Clinical correlates of the presence of the Asp816Val c-kit mutation in the peripheral blood mononuclear cells of patients with mastocytosis.
|
| Worobec AS, et al.
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| Cancer 83 : 2120-2129. 1998
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| 44 | CSF1R, HMGXB3, KIT
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| Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.
|
| Andre C, Hampe A, Lachaume P, Martin E, Wang XP, Manus V, Hu WX, Galibert F.
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| Genomics 39 : 216-226. 1997
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| 45 | KIT, FMST
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| A new c-kit mutation in a case of aggressive mast cell disease.
|
| Pignon JM, et al.
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| Br J Haematol 96 : 374-376. 1997
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| 46 | KIT, FMST
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| Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis : establishment of clonality in a human mast cell neoplasm.
|
| Longley BJ, et al.
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| Nat Genet 12 : 312-314. 1996
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| 47 | KIT, PBT1
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| Mutations in the ligand-binding domain of the kit receptor : an uncommon site in human piebaldism.
|
| Fleischman RA, et al.
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| J Invest Dermatol 107 : 703-706. 1996
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| 48 | KIT, FMST
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| Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.
|
| Nagata H, Worobec AS, Oh CK, Chowdhury BA, Tannenbaum S, Suzuki Y, Metcalfe DD.
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| Proc Natl Acad Sci U S A 92 : 10560-10564. 1995
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| 49 | PBT1, KIT
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| A 12-bp deletion (7818del12) in the c-kit protooncogene in a large Italian kindred with piebaldism.
|
| Riva P, et al.
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| Hum Mutat 6 : 343-345. 1995
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| 50 | PBT1, KIT
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| Human piebaldism : relationship between phenotype and site of kit gene mutation.
|
| Ward KA, et al.
|
| Br J Dermatol 132 : 929-935. 1995
|
| 51 | PBT1, KIT
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| Novel mutations and deletions of the KIT (Steel Factor Receptor) gene inhuman piebaldism.
|
| Ezoe K, et al.
|
| Am J Hum Genet 56 : 58-66. 1995
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| 52 | PDGFRA, KDR, KIT, EPHA5
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| A YAC contig spanning a cluster of human type III receptor protein tyrosine kinase genes (PDGFRA-KIT-KDR) in chromosome segment 4q12.
|
| Spritz RA, et al.
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| Genomics 22 : 431-436. 1994
|
| 53 | PBT1, KIT
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| A novel mutation in the c-KIT protooncogene in a family with piebaldism. (abstr)
|
| Larizza L, et al.
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| Am J Hum Genet 55 : A228. 1994
|
| 54 | PBT1, KIT
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| A recurrent deletion in the KIT (mast/stem cell growth factor receptor) proto-oncogene is a frequent cause of human piebaldism.
|
| Spritz RA, et al.
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| Hum Mol Genet 2 : 1499-1500. 1993
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| 55 | KIT
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| Polymerase chain reaction detection of a novel human KIT (mast/stem cell growth factor receptor) gene polymorphism by single-strand conformation polymorphism analysis or by SmaI or BstNI cleavage.
|
| Spritz RA, et al.
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| Hum Genet 92 : 208-209. 1993
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| 56 | KIT, PTPN6
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| Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand.
|
| Yi T, Ihle JN.
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| Mol Cell Biol 13(6):3350-8. 1993
|
| 57 | KIT
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| Genomic organization of the human c-kit gene : evolution of the receptor tyrosine kinase subclass III.
|
| AndrŽ C, et al.
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| Oncogene 7 : 685-691. 1992
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| 58 | KIT
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| Cloning and structural analysis of the human c-kit gene.
|
| Vandenbark GR, et al.
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| Oncogene 7 : 1259-1266. 1992
|
| 59 | KIT, PBT1
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| Mutations of the KIT (mast/stem cell growth factor receptor) proto-oncogene account for a continuous range of phenotypes in human piebaldism.
|
| Spritz RA, et al.
|
| Am J Hum Genet 51 : 1058-1065. 1992
|
| 60 | KIT
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| Organization and nucleotide sequence of the human KIT (mast/stem cell growth factor receptor) proto-oncogene.
|
| Giebel LB, et al.
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| Oncogene 7 : 2207-2217. 1992
|
| 61 | KIT
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| Expression of messenger RNA for kit-ligand in human placenta : localization by in situ hybridization and identification of alternatively spliced variants.
|
| Sharkey A, et al.
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| Mol Endocrinol 6 : 1235-1241. 1992
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| 62 | KIT
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| Expression of two types of kit ligand mRNAs in human tumor cells.
|
| Toyota M, et al.
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| Int J Haematol 55 : 301-304. 1992
|
| 63 | KIT
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| TaqI RFLP at the c-kit oncogene locus (KIT).
|
| Drachtman RA, et al.
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| Nucleic Acids Res 19 : 6975. 1991
|
| 64 | KIT
|
| c-kit expression by CD34+ bone marrow progenitors and inhibition of response to recombinant human interleukin-3 following exposure to c-kit antisense oligonucleotides.
|
| Catlett JP, et al.
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| Blood 78 : 3186-3191. 1991
|
| 65 | KITLG, KIT
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| Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer.
|
| Hibi K, et al.
|
| Oncogene 6 : 2291-2296. 1991
|
| 66 | KIT
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| Detecting high-resolution polymorphisms in human coding loci by combining PCR and single-strand conformation polymorphism (SSCP) analysis.
|
| Poduslo SE, et al.
|
| Am J Hum Genet 49 : 106-111. 1991
|
| 67 | KIT
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| An Sstl RFLP at the C-Kit oncogene locus (KIT).
|
| Curtis D.
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| Nucleic Acids Res 19 : 1352. 1991
|
| 68 | KIT
|
| Localization of the human c-kit protooncogene on the q11-q12 region of chromosome 4.
|
| d'Auriol L, et al.
|
| Hum Genet 78 : 374-376. 1988
|
| 69 | KIT
|
| A HindIII RFLP demonstrated for the kit oncogene on chromosome 4.
|
| Berdahl LD, et al.
|
| Nucleic Acids Res 16 : 4740. 1988
|
| 70 | KIT
|
| The oncogene c-KIT is located on human chromosome 4 and mouse chromosome 5.
|
| Yang-Feng TL, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 723. 1987
|
| 71 | KIT
|
| Assignment of the human c-kit proto-oncogene to the q11-q12 region of chromosome 4, using in situ hybridization.
|
| Mattei MG, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 657. 1987
|