Citations for
1FGF8, GLI3, KIF7
Altered GLI3 and FGF8 signaling underlies Acrocallosal syndrome phenotypes in Kif7 depleted mice.
Putoux A, Baas D, Paschaki M, Morlé L, Maire C, Attié-Bitach T, Thomas S, Durand B.
Hum Mol Genet um Mol Genet. 2018 Nov 15. doi: 10.1093/hmg/ddy392. [Epub ahead of print] 2018
2ARL3, KIF17, KIF7, RP2
Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.
Schwarz N, Lane A, Jovanovic K, Parfitt DA, Aguila M, Thompson CL, da Cruz L, Coffey PJ, Chapple JP, Hardcastle AJ, Cheetham ME.
Hum Mol Genet 26(13):2480-2492. doi: 10.1093/hmg/ddx143. 2017
3KIF17, KIF7
Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms.
Lewis TR, Kundinger SR, Pavlovich AL, Bostrom JR, Link BA, Besharse JC.
Dev Biol 425(2):176-190. doi: 10.1016/j.ydbio.2017.03.019. Epub 2017 Mar 22. 2017
4HAUS2, HAUS4, HAUS5, KIF7, NPHP1, TMEM237, ZNF131
ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5.
Ding Y, Herman JA, Toledo CM, Lang JM, Corrin P, Girard EJ, Basom R, Delrow JJ, Olson JM, Paddison PJ.
Oncotarget 8(30):48545-48562. doi: 10.18632/oncotarget.18153. 2017
5KIF7, SUFU
Sufu and Kif7 in limb patterning and development.
Zhulyn O, Hui CC.
Dev Dyn 244(3):468-78. doi: 10.1002/dvdy.24249. Epub 2015 Jan 24. 2015
6GLI2, KIF7, SUFU
Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling.
Law KK, Makino S, Mo R, Zhang X, Puviindran V, Hui CC.
PLoS One 7(11):e50193. doi: 10.1371/journal.pone.0050193. Epub 2012 Nov 16. 2012
7GLI2, KIF7, SUFU
Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis.
Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC.
Development 139(22):4152-61. doi: 10.1242/dev.081190. Epub 2012 Oct 3. 2012
8EDMM, KIF7
A mutation in KIF7 is responsible for the autosomal recessive syndrome of macrocephaly, multiple epiphyseal dysplasia and distinctive facial appearance.
Ali BR, Silhavy JL, Akawi NA, Gleeson JG, Al-Gazali L.
Orphanet J Rare Dis 7:27. doi: 10.1186/1750-1172-7-27. 2012
9ACLS2, HYSL2, KIF7
KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes.
Putoux A, Thomas S, Coene KL, Davis EE, Alanay Y, Ogur G, Uz E, Buzas D, Gomes C, Patrier S, Bennett CL, Elkhartoufi N, Frison MH, Rigonnot L, Joyé N, Pruvost S, Utine GE, Boduroglu K, Nitschke P, Fertitta L, Thauvin-Robinet C, Munnich A, Cormier-Daire V, Hennekam R, Colin E, Akarsu NA, Bole-Feysot C, Cagnard N, Schmitt A, Goudin N, Lyonnet S, Encha-Razavi F, Siffroi JP, Winey M, Katsanis N, Gonzales M, Vekemans M, Beales PL, Attié-Bitach T.
Nat Genet 43(6):601-6. Epub 2011 May 8. 2011
10KIF7
Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu.
Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA.
Development. 138(17):3791-801. 2011
11KIF7
Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.
Liem KF Jr, He M, Ocbina PJ, Anderson KV.
Proc Natl Acad Sci U S A 106(32):13377-82. Epub 2009 Jul 29. 2009
12GLI3, KIF7
The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.
Endoh-Yamagami S, Evangelista M, Wilson D, Wen X, Theunissen JW, Phamluong K, Davis M, Scales SJ, Solloway MJ, de Sauvage FJ, Peterson AS.
Curr Biol 19(15):1320-6. Epub 2009 Jul 9. 2009
13KIF7
The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling.
Cheung HO, Zhang X, Ribeiro A, Mo R, Makino S, Puviindran V, Law KK, Briscoe J, Hui CC.
Sci Signal 2(76):ra29. 2009
14BTRC, CREBBP, CSRP2, FKBP8, GAS1, GSK3B, HHAT, HHIP, IFT88, KIF27, KIF3A, KIF7, RAB23, SHH, STIL, STK36, SUFU, VTN
Hedgehog signaling and congenital malformations.
Nieuwenhuis E, Hui CC.
Clin Genet 67(3):193-208. 2005
15KIF7
A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo.
Tay SY, Ingham PW, Roy S.
Development 132(4):625-34. Epub 2005 Jan 12. 2005
16KIF7, KIF27
KIF27 is one of orthologs for Drosophila Costal-2.
Katoh Y, Katoh M.
Int J Oncol 25(6):1875-80. 2004