Citations for
1DCLK1, KIF1A
Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites.
Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC.
EMBO J 35(3):302-18. doi: 10.15252/embj.201592929. Epub 2016 Jan 12. 2016
2KIF1A, MRD9
De novo KIF1A mutations cause intellectual deficit, cerebellar atrophy, lower limb spasticity and visual disturbance.
Ohba C, Haginoya K, Osaka H, Kubota K, Ishiyama A, Hiraide T, Komaki H, Sasaki M, Miyatake S, Nakashima M, Tsurusaki Y, Miyake N, Tanaka F, Saitsu H, Matsumoto N.
J Hum Genet Hum Genet. 2015 Sep 10. doi: 10.1038/jhg.2015.108. [Epub ahead of print] 2015
3KIF1A, MRD9
De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy.
Esmaeeli Nieh S, Madou MR, Sirajuddin M, Fregeau B, McKnight D, Lexa K, Strober J, Spaeth C, Hallinan BE, Smaoui N, Pappas JG, Burrow TA, McDonald MT, Latibashvili M, Leshinsky-Silver E, Lev D, Blumkin L, Vale RD, Barkovich AJ, Sherr EH.
Ann Clin Transl Neurol 2(6):623-35. doi: 10.1002/acn3.198. Epub 2015 May 1. 2015
4KIF1A, MRD9
De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy.
Esmaeeli Nieh S, Madou MR, Sirajuddin M, Fregeau B, McKnight D, Lexa K, Strober J, Spaeth C, Hallinan BE, Smaoui N, Pappas JG, Burrow TA, McDonald MT, Latibashvili M, Leshinsky-Silver E, Lev D, Blumkin L, Vale RD, Barkovich AJ, Sherr EH.
Ann Clin Transl Neurol 2(6):623-35. doi: 10.1002/acn3.198. Epub 2015 May 1. 2015
5KIF1A, SPG30
Dominant transmission of de novo KIF1A motor domain variant underlying pure spastic paraplegia.
Ylikallio E, Kim D, Isohanni P, Auranen M, Kim E, Lönnqvist T, Tyynismaa H.
Eur J Hum Genet 23(10):1427-30. doi: 10.1038/ejhg.2014.297. Epub 2015 Jan 14. 2015
6KIF1A, MRD9
De novo mutations in the motor domain of KIF1A cause cognitive impairment, spastic paraparesis, axonal neuropathy, and cerebellar atrophy.
Lee JR, Srour M, Kim D, Hamdan FF, Lim SH, Brunel-Guitton C, Décarie JC, Rossignol E, Mitchell GA, Schreiber A, Moran R, Van Haren K, Richardson R, Nicolai J, Oberndorff KM, Wagner JD, Boycott KM, Rahikkala E, Junna N, Tyynismaa H, Cuppen I, Verbeek NE, Stumpel CT, Willemsen MA, de Munnik SA, Rouleau GA, Kim E, Kamsteeg EJ, Kleefstra T, Michaud JL.
Hum Mutat 36(1):69-78. doi: 10.1002/humu.22709. Epub 2014 Nov 27. 2015
7KIF1A
Differential promoter methylation of kinesin family member 1a in plasma is associated with breast cancer and DNA repair capacity.
Guerrero-Preston R, Hadar T, Ostrow KL, Soudry E, Echenique M, Ili-Gangas C, Pérez G, Perez J, Brebi-Mieville P, Deschamps J, Morales L, Bayona M, Sidransky D, Matta J.
Oncol Rep 32(2):505-12. doi: 10.3892/or.2014.3262. Epub 2014 Jun 13. 2014
8KIF1A, KIF5B
Diabetes alters KIF1A and KIF5B motor proteins in the hippocampus.
Baptista FI, Pinto MJ, Elvas F, Almeida RD, Ambrósio AF.
PLoS One 8(6):e65515. doi: 10.1371/journal.pone.0065515. Print 2013. 2013
9KIF1A
The kinesin-3, unc-104 regulates dendrite morphogenesis and synaptic development in Drosophila.
Kern JV, Zhang YV, Kramer S, Brenman JE, Rasse TM.
Genetics 195(1):59-72. doi: 10.1534/genetics.113.151639. Epub 2013 Jun 14. 2013
10KIF1A
The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A.
Huo L, Yue Y, Ren J, Yu J, Liu J, Yu Y, Ye F, Xu T, Zhang M, Feng W.
Structure 20(9):1550-61. doi: 10.1016/j.str.2012.07.002. Epub 2012 Aug 2. 2012
11DCLK1, DCX, KIF1A
Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins.
Liu JS, Schubert CR, Fu X, Fourniol FJ, Jaiswal JK, Houdusse A, Stultz CM, Moores CA, Walsh CA.
Mol Cell 47(5):707-21. doi: 10.1016/j.molcel.2012.06.025. Epub 2012 Aug 1. 2012
12KIF1A
Motor protein KIF1A is essential for hippocampal synaptogenesis and learning enhancement in an enriched environment.
Kondo M, Takei Y, Hirokawa N.
Neuron 73(4):743-57. doi: 10.1016/j.neuron.2011.12.020. 2012
13KIF1A, SPG30
KIF1A missense mutations in SPG30, an autosomal recessive spastic paraplegia: distinct phenotypes according to the nature of the mutations.
Klebe S, Lossos A, Azzedine H, Mundwiller E, Sheffer R, Gaussen M, Marelli C, Nawara M, Carpentier W, Meyer V, Rastetter A, Martin E, Bouteiller D, Orlando L, Gyapay G, El-Hachimi KH, Zimmerman B, Gamliel M, Misk A, Lerer I, Brice A, Durr A, Stevanin G.
Eur J Hum Genet 20(6):645-9. doi: 10.1038/ejhg.2011.261. Epub 2012 Jan 18. 2012
14KIF1A
Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis.
Erlich Y, Edvardson S, Hodges E, Zenvirt S, Thekkat P, Shaag A, Dor T, Hannon GJ, Elpeleg O.
Genome Res. 2011
15HSN2C, KIF1A
KIF1A, an Axonal Transporter of Synaptic Vesicles, Is Mutated in Hereditary Sensory and Autonomic Neuropathy Type 2.
Rivičre JB, Ramalingam S, Lavastre V, Shekarabi M, Holbert S, Lafontaine J, Srour M, Merner N, Rochefort D, Hince P, Gaudet R, Mes-Masson AM, Baets J, Houlden H, Brais B, Nicholson GA, Van Esch H, Nafissi S, De Jonghe P, Reilly MM, Timmerman V, Dion PA, Rouleau GA.
Am J Hum Genet 89(2):219-30. Epub 2011 Aug 4. 2011
16KIF1A
KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons.
Lo KY, Kuzmin A, Unger SM, Petersen JD, Silverman MA.
Neurosci Lett 491(3):168-73. doi: 10.1016/j.neulet.2011.01.018. Epub 2011 Jan 21. 2011
17KIF1A
Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear migration in neural stem cells.
Tsai JW, Lian WN, Kemal S, Kriegstein AR, Vallee RB.
Nat Neurosci 13(12):1463-71. doi: 10.1038/nn.2665. Epub 2010 Oct 31. 2010
18KIF1A, KIF1B, KIF1C
The kinesin-1 motor protein is regulated by a direct interaction of its head and tail.
Dietrich KA, Sindelar CV, Brewer PD, Downing KH, Cremo CR, Rice SE.
Proc Natl Acad Sci U S A 105(26):8938-43. Epub 2008 Jun 25. 2008
19KIF1A
High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations.
Kikkawa M, Hirokawa N.
EMBO J 25(18):4187-94. Epub 2006 Aug 31. 2006
20ACTR1B, B3GALT1, C2orf19, C2orf27A, C2orf29, C2orf39, C4orf23, C4orf28, CCDC104, CCDC74A, CCDC75, CSRNP3, CTNNA2, ELOVL6, EMX1, FASTKD2, INMT, INPP4A, KIF1A, MMADHC, OTX1, RFTN2, RNF103, TBC1D14, TSSC1, ZNF514
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K, Sekhon M, Becker MC, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Kremitzki C, Oddy L, Du H, Sun H, Bradshaw-Cordum H, Ali J, Carter J, Cordes M, Harris A, Isak A, van Brunt A, Nguyen C, Du F, Courtney L, Kalicki J, Ozersky P, Abbott S, Armstrong J, Belter EA, Caruso L, Cedroni M, Cotton M, Davidson T, Desai A, Elliott G, Erb T, Fronick C, Gaige T, Haakenson W, Haglund K, Holmes A, Harkins R, Kim K, Kruchowski SS, Strong CM, Grewal N, Goyea E, Hou S, Levy A, Martinka S, Mead K, McLellan MD, Meyer R, Randall-Maher J, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Shah N, Swearengen-Shahid S, Snider J, Strong JT, Thompson J, Yoakum M, Leonard S, Pearman C, Trani L, Radionenko M, Waligorski JE, Wang C, Rock SM, Tin-Wollam AM, Maupin R, Latreille P, Wendl MC, Yang SP, Pohl C, Wallis JW, Spieth J, Bieri TA, Berkowicz N, Nelson JO, Osborne J, Ding L, Meyer R, Sabo A, Shotland Y, Sinha P, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Jones TA, She X, Ciccarelli FD, Izaurralde E, Taylor J, Schmutz J, Myers RM, Cox DR, Huang X, McPherson JD, Mardis ER, Clifton SW, Warren WC, Chinwalla AT, Eddy SR, Marra MA, Ovcharenko I, Furey TS, Miller W, Eichler EE, Bork P, Suyama M, Torrents D, Waterston RH, Wilson RK.
Nature 434(7034):724-31. 2005
21KIF1A
Herpes simplex virus type 2 membrane protein UL56 associates with the kinesin motor protein KIF1A.
Koshizuka T, Kawaguchi Y, Nishiyama Y.
J Gen Virol. 86(Pt 3):527-33. 2005
22KIF1A
An intramolecular interaction between the FHA domain and a coiled coil negatively regulates the kinesin motor KIF1A.
Lee JR, Shin H, Choi J, Ko J, Kim S, Lee HW, Kim K, Rho SH, Lee JH, Song HE, Eom SH, Kim E.
EMBO J 23(7):1506-15. Epub 2004 Mar 11. 2004
23KIF1A, KIF2A, KIFC3
Kinesin superfamily proteins and their various functions and dynamics.
Hirokawa N, Takemura R.
Exp Cell Res 301(1):50-9. Review. 2004
24KIF1A
Association of the kinesin motor KIF1A with the multimodular protein liprin-alpha.
Shin H, Wyszynski M, Huh KH, Valtschanoff JG, Lee JR, Ko J, Streuli M, Weinberg RJ, Sheng M, Kim E.
J Biol Chem. 278(13):11393-401. 2003
25BDMR, DEL2Q37, GBX2, GPC1, HDLBP, KIF1A
Molecular genetic delineation of 2q37.3 deletion in autism and osteodystrophy: report of a case and of new markers for deletion screening by PCR.
Smith M, Escamilla JR, Filipek P, Bocian ME, Modahl C, Flodman P, Spence MA.
Cytogenet Cell Genet 94(1-2):15-22. 2001
26KIF1A
Mapping of the kinesin-related gene ATSV to chromosome 2q37.
Keller MP, et al.
Hum Genet 104(3):254-6. 1999
27KIF1A
Characterization of a kinesin-related gene ATSV, within the tuberous sclerosis locus (TSC1) candidate region on chromosome 9q34.
Furlong RA, et al.
Genomics 33 : 421-429. 1996