Citations for
1(KIF10, KIF, KIF11, KIF14, KIF15, KIF17, KIF18A, KIF18B, KIF20A, KIF20B, KIF22, KIF23, KIF24, KIF26B, KIF2C, KIF3B, KIF4A, KIFC17
Overexpression of kinesin superfamily members as prognostic biomarkers of breast cancer.
Li TF, Zeng HJ, Shan Z, Ye RY, Cheang TY, Zhang YJ, Lu SH, Zhang Q, Shao N, Lin Y.
Cancer Cell Int 20:123. doi: 10.1186/s12935-020-01191-1. eCollection 2020. 2020
2KIF11
A mouse model for kinesin family member 11 (Kif11)-associated familial exudative vitreoretinopathy.
Wang Y, Smallwood PM, Williams J, Nathans J.
Hum Mol Genet 29(7):1121-1131. doi: 10.1093/hmg/ddaa018. 2020
3KIF11, KIFC1, TRIM8
TRIM8 interacts with KIF11 and KIFC1 and controls bipolar spindle formation and chromosomal stability.
Venuto S, Monteonofrio L, Cozzolino F, Monti M, Appolloni I, Mazza T, Canetti D, Giambra V, Panelli P, Fusco C, Squeo GM, Croce AI, Pucci P, Malatesta P, Soddu S, Merla G, Micale L.
Cancer Lett 473:98-106. doi: 10.1016/j.canlet.2019.12.042. Epub 2020 Jan 2. 2020
4KIF11
Kinesin Family Member 11 Enhances the Self-Renewal Ability of Breast Cancer Cells by Participating in the Wnt/β-Catenin Pathway.
Pei YY, Li GC, Ran J, Wan XH, Wei FX, Wang L.
J Breast Cancer 22(4):522-532. doi: 10.4048/jbc.2019.22.e51. eCollection 2019 Dec. 2019
5KIF11, KIFC3, NEK2
The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly.
Hata S, Pastor Peidro A, Panic M, Liu P, Atorino E, Funaya C, Jäkle U, Pereira G, Schiebel E.
Nat Cell Biol 21(9):1138-1151. doi: 10.1038/s41556-019-0382-6. Epub 2019 Sep 2. 2019
6EVR8, KIF11
Clinical and Molecular Characterization of Familial Exudative Vitreoretinopathy Associated With Microcephaly.
Hull S, Arno G, Ostergaard P, Pontikos N, Robson AG, Webster AR, Hogg CR, Wright GA, Henderson RHH, Martin CA, Jackson AP, Mansour S, Moore AT, Michaelides M.
Am J Ophthalmol 207:87-98. doi: 10.1016/j.ajo.2019.05.001. Epub 2019 May 8. 2019
7KIF11
KIF11 Functions as an Oncogene and Is Associated with Poor Outcomes from Breast Cancer.
Zhou J, Chen WR, Yang LC, Wang J, Sun JY, Zhang WW, He ZY, Wu SG.
Cancer Res Treat 51(3):1207-1221. doi: 10.4143/crt.2018.460. Epub 2018 Dec 27. 2019
8KF13B, KIF11, KIF21B
Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms.
Swarnkar S, Avchalumov Y, Raveendra BL, Grinman E, Puthanveettil SV.
Sci Rep 8(1):17419. doi: 10.1038/s41598-018-35634-7. 2018
9KIF11, TPX2
Distribution of Eg5 and TPX2 in mitosis: Insight from CRISPR tagged cells.
Mann BJ, Wadsworth P.
Cytoskeleton (Hoboken) 75(12):508-521. doi: 10.1002/cm.21486. Epub 2018 Nov 15. 2018
10KIF11, NEK7
NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization.
Freixo F, Martinez Delgado P, Manso Y, Sánchez-Huertas C, Lacasa C, Soriano E, Roig J, Lüders J.
Nat Commun 9(1):2330. doi: 10.1038/s41467-018-04706-7. 2018
11KIF11
Novel Insights Into the Phenotypical Spectrum of KIF11-Associated Retinopathy, Including a New Form of Retinal Ciliopathy.
Birtel J, Gliem M, Mangold E, Tebbe L, Spier I, Müller PL, Holz FG, Neuhaus C, Wolfrum U, Bolz HJ, Charbel Issa P.
Invest Ophthalmol Vis Sci 58(10):3950-3959. doi: 10.1167/iovs.17-21679. 2017
12KIF11
Src family kinase phosphorylation of the motor domain of the human kinesin-5, Eg5.
Bickel KG, Mann BJ, Waitzman JS, Poor TA, Rice SE, Wadsworth P.
Cytoskeleton (Hoboken) 74(9):317-330. doi: 10.1002/cm.21380. Epub 2017 Jul 25. 2017
13EVR1, EVR2, EVR4, EVR5, EVR6, EVR8, FZD4, KIF11, LRP5, NDP, TSPAN12, ZNF408
Mutations in LRP5,FZD4, TSPAN12, NDP, ZNF408, or KIF11 Genes Account for 38.7% of Chinese Patients With Familial Exudative Vitreoretinopathy.
Rao FQ, Cai XB, Cheng FF, Cheng W, Fang XL, Li N, Huang XF, Li LH, Jin ZB.
Invest Ophthalmol Vis Sci 58(5):2623-2629. doi: 10.1167/iovs.16-21324. 2017
14KIF11
Kinesin Family Member 11 mRNA Expression Predicts Prostate Cancer Aggressiveness.
Piao XM, Byun YJ, Jeong P, Ha YS, Yoo ES, Yun SJ, Kim WJ.
Clin Genitourin Cancer 15(4):450-454. doi: 10.1016/j.clgc.2016.10.005. Epub 2016 Oct 19. 2017
15KIF11, PTEN
PTEN regulates EG5 to control spindle architecture and chromosome congression during mitosis.
He J, Zhang Z, Ouyang M, Yang F, Hao H, Lamb KL, Yang J, Yin Y, Shen WH.
Nat Commun 7:12355. doi: 10.1038/ncomms12355. 2016
16DLG1, KIF11, PTEN
Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes.
van Ree JH, Nam HJ, Jeganathan KB, Kanakkanthara A, van Deursen JM.
Nat Cell Biol 18(7):814-21. doi: 10.1038/ncb3369. Epub 2016 May 30. 2016
17EVR8, KIF11
Identification of novel KIF11 mutations in patients with familial exudative vitreoretinopathy and a phenotypic analysis.
Li JK, Fei P, Li Y, Huang QJ, Zhang Q, Zhang X, Rao YQ, Li J, Zhao P.
Sci Rep 6:26564. doi: 10.1038/srep26564. 2016
18FBXO30, KIF11
Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5.
Liu Y, Wang Y, Du Z, Yan X, Zheng P, Liu Y.
Cell Rep 15(5):1111-1122. doi: 10.1016/j.celrep.2016.03.083. Epub 2016 Apr 21. 2016
19KIF11
Kinesin-5 is a microtubule polymerase.
Chen Y, Hancock WO.
Nat Commun 6:8160. doi: 10.1038/ncomms9160. 2015
20KIF11, TPX2
TPX2 regulates neuronal morphology through kinesin-5 interaction.
Kahn OI, Ha N, Baird MA, Davidson MW, Baas PW.
Cytoskeleton (Hoboken) 72(7):340-8. doi: 10.1002/cm.21234. Epub 2015 Aug 22. 2015
21ACTB, IGF2BP1, KIF11
Specific interaction of KIF11 with ZBP1 regulates the transport of β-actin mRNA and cell motility.
Song T, Zheng Y, Wang Y, Katz Z, Liu X, Chen S, Singer RH, Gu W.
J Cell Sci 128(5):1001-10. doi: 10.1242/jcs.161679. Epub 2015 Jan 14. 2015
22KIF11, KIF15
Balanced activity of three mitotic motors is required for bipolar spindle assembly and chromosome segregation.
van Heesbeen RG, Tanenbaum ME, Medema RH.
Cell Rep 8(4):948-56. doi: 10.1016/j.celrep.2014.07.015. Epub 2014 Aug 7. 2014
23KIF11
Kinetochore-microtubule stability governs the metaphase requirement for Eg5.
Gayek AS, Ohi R.
Mol Biol Cell 25(13):2051-60. doi: 10.1091/mbc.E14-03-0785. Epub 2014 May 7. 2014
24KIF11, NUMA1
Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment.
Iwakiri Y, Kamakura S, Hayase J, Sumimoto H.
Biochem J 451(2):195-204. doi: 10.1042/BJ20121447. 2013
25KIF11
The bipolar assembly domain of the mitotic motor kinesin-5.
Acar S, Carlson DB, Budamagunta MS, Yarov-Yarovoy V, Correia JJ, Niñonuevo MR, Jia W, Tao L, Leary JA, Voss JC, Evans JE, Scholey JM.
Nat Commun 4:1343. doi: 10.1038/ncomms2348. 2013
26KIF11, MLCD2
Mutations in KIF11 Cause Autosomal-Dominant Microcephaly Variably Associated with Congenital Lymphedema and Chorioretinopathy.
Ostergaard P, Simpson MA, Mendola A, Vasudevan P, Connell FC, van Impel A, Moore AT, Loeys BL, Ghalamkarpour A, Onoufriadis A, Martinez-Corral I, Devery S, Leroy JG, van Laer L, Singer A, Bialer MG, McEntagart M, Quarrell O, Brice G, Trembath RC, Schulte-Merker S, Makinen T, Vikkula M, Mortimer PS, Mansour S, Jeffery S.
Am J Hum Genet 90(2):356-62. Epub 2012 Jan 26. 2012
27AGBL2, KIF11, RARRES1
Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the α-tubulin tyrosination cycle.
Sahab ZJ, Hall MD, Me Sung Y, Dakshanamurthy S, Ji Y, Kumar D, Byers SW.
Cancer Res 71(4):1219-28. Epub 2011 Feb 8. 2011
28KIF11, NEK7, NEK9, PLK1
Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5.
Bertran MT, Sdelci S, Regué L, Avruch J, Caelles C, Roig J.
EMBO J 30(13):2634-47. doi: 10.1038/emboj.2011.179. 2011
29CDK1, CEP250, KIF11
Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1.
Smith E, Hégarat N, Vesely C, Roseboom I, Larch C, Streicher H, Straatman K, Flynn H, Skehel M, Hirota T, Kuriyama R, Hochegger H.
EMBO J 30(11):2233-45. Epub 2011 Apr 26. 2011
30KIF11, TPX2
TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle.
Ma N, Titus J, Gable A, Ross JL, Wadsworth P.
J Cell Biol 195(1):87-98. 2011
31KIF11, LMNB1
Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly.
Goodman B, Channels W, Qiu M, Iglesias P, Yang G, Zheng Y.
J Biol Chem 285(45):35238-44. Epub 2010 Sep 8. 2010
32KIF11, NPM1
Nucleophosmin/B23 inhibits Eg5-mediated microtubule depolymerization by inactivating its ATPase activity.
Wang G, Gao X, Huang Y, Yao Z, Shi Q, Wu M.
J Biol Chem 285(25):19060-7. Epub 2010 Apr 19. 2010
33KIF11, TPX2
Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux.
Ma N, Tulu US, Ferenz NP, Fagerstrom C, Wilde A, Wadsworth P.
Mol Biol Cell 21(6):979-88. Epub 2010 Jan 28. 2010
34KIF11
KIF11 inhibition for glioblastoma treatment: reason to hope or a struggle with the brain?
Valensin S, Ghiron C, Lamanna C, Kremer A, Rossi M, Ferruzzi P, Nievo M, Bakker A.
BMC Cancer 9:196. 2009
35KIF11, TNXB
Truncated form of tenascin-X, XB-S, interacts with mitotic motor kinesin Eg5.
Endo T, Ariga H, Matsumoto K.
Mol Cell Biochem 320(1-2):53-66. Epub 2008 Aug 5. 2009
36KIF11, KIF15
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
Tanenbaum ME, Macůrek L, Janssen A, Geers EF, Alvarez-Fernández M, Medema RH.
Curr Biol 19(20):1703-11. doi: 10.1016/j.cub.2009.08.027. Epub 2009 Oct 8. 2009
37KIF11
Disruption of the mitotic kinesin Eg5 gene (Knsl1) results in early embryonic lethality.
Chauvière M, Kress C, Kress M.
Biochem Biophys Res Commun 372(4):513-9. Epub 2008 May 12. 2008
38KIF11, PRKN
Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase.
Liu M, Aneja R, Sun X, Xie S, Wang H, Wu X, Dong JT, Li M, Joshi HC, Zhou J.
J Biol Chem 283(51):35783-8. Epub 2008 Oct 9. 2008
39KIF11
Kinesin-5 is essential for growth-cone turning.
Nadar VC, Ketschek A, Myers KA, Gallo G, Baas PW.
Curr Biol 18(24):1972-7. Epub 2008 Dec 11. 2008
40HHEX, SLC30A8, KIF11, IDE
A genome-wide association study identifies novel risk loci for type 2 diabetes.
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P.
Nature 445(7130):881-5. Epub 2007 Feb 11. 2007
41AP1S1, ATP6V1D, BM22, CASP8AP2, CDC16, CDC27, CENPE, CLDN16, CMTM4, CYTH3, DDX5, DHX8, EIF3A, EIF3H, EIF4A3, GALNT5, ITPR1, KIF11, KPNB1, LSM6, MFAP1, NCAPD3, NCAPG2, RBM19, RRM2, SART1, SNRPA1, SNRPB, SNW1, SPC25, VCP, ZDHHC5
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division.
Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, Drechsel D, Fischer S, Konstantinova I, Habermann B, Grabner H, Yaspo ML, Himmelbauer H, Korn B, Neugebauer K, Pisabarro MT, Buchholz F.
Nature 432(7020):1036-40. 2004
42KIF11
Expanding the role of HsEg5 within the mitotic and post-mitotic phases of the cell cycle.
Whitehead CM, Rattner JB.
J Cell Sci 111 ( Pt 17):2551-61. 1998
43CDK1, KIF11
Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo.
Blangy A, Lane HA, d'Herin P, Harper M, Kress M, Nigg EA.
Cell 83(7):1159-69. 1995
44KIF11
Localization of the human kinesin-related gene to band 10q24 by fluorescence in situ hybridization.
Tihy F, et al.
Genomics 13 : 1371-1372. 1992