Citations for
The transcriptional co-activator SND1 is a novel regulator of alternative splicing in prostate cancer cells.
Cappellari M, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Saarikettu J, Silvennoinen O, Sette C.
Oncogene 33(29):3794-802. doi: 10.1038/onc.2013.360. Epub 2013 Sep 2. 2014
Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells.
Fu K, Sun X, Zheng W, Wier EM, Hodgson A, Tran DQ, Richard S, Wan F.
Nat Commun 4:1909. doi: 10.1038/ncomms2916. 2013
Sam68 interacts with IRS1.
Quintana-Portillo R, Canfrán-Duque A, Issad T, Sánchez-Margalet V, González-Yanes C.
Biochem Pharmacol 83(1):78-87. Epub 2011 Oct 10. 2012
Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.
Asbach B, Ludwig C, Saksela K, Wagner R.
PLoS One 7(6):e38540. doi: 10.1371/journal.pone.0038540. Epub 2012 Jun 20. 2012
The Sam68 STAR RNA-binding protein regulates mTOR alternative splicing during adipogenesis.
Huot MÉ, Vogel G, Zabarauskas A, Ngo CT, Coulombe-Huntington J, Majewski J, Richard S.
Mol Cell 46(2):187-99. doi: 10.1016/j.molcel.2012.02.007. Epub 2012 Mar 15. 2012
SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.
Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S, Scheiffele P.
Cell 147(7):1601-14. 2011
Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor.
Ramakrishnan P, Baltimore D.
Mol Cell 43(2):167-79. Epub 2011 May 27. 2011
Met receptors induce Sam68-dependent cell migration by activation of alternate extracellular signal-regulated kinase family members.
Locatelli A, Lange CA.
J Biol Chem 286(24):21062-72. Epub 2011 Apr 13. 2011
Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.
Sánchez-Jiménez F, Pérez-Pérez A, González-Yanes C, Najib S, Varone CL, Sánchez-Margalet V.
Mol Cell Endocrinol 332(1-2):221-7. Epub 2010 Oct 28. 2011
Ablation of the Sam68 gene impairs female fertility and gonadotropin-dependent follicle development.
Bianchi E, Barbagallo F, Valeri C, Geremia R, Salustri A, De Felici M, Sette C.
Hum Mol Genet 19(24):4886-94. Epub 2010 Sep 29. 2010
The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.
Pedrotti S, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Stamm S, Manley JL, Sette C.
EMBO J 29(7):1235-47. Epub 2010 Feb 25. 2010
Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients.
Sellier C, Rau F, Liu Y, Tassone F, Hukema RK, Gattoni R, Schneider A, Richard S, Willemsen R, Elliott DJ, Hagerman PJ, Charlet-Berguerand N.
EMBO J 29(7):1248-61. Epub 2010 Feb 25. 2010
Sam68 regulates a set of alternatively spliced exons during neurogenesis.
Chawla G, Lin CH, Han A, Shiue L, Ares M Jr, Black DL
Mol Cell Biol 29(1):201-13 2009
Sam68 relocalization into stress granules in response to oxidative stress through complexing with TIA-1.
Henao-Mejia J, He JJ.
Exp Cell Res 315(19):3381-95. Epub 2009 Jul 14. 2009
Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis.
Richard S, Vogel G, Huot ME, Guo T, Muller WJ, Lukong KE.
Oncogene 27(4):548-56. Epub 2007 Jul 9.PMID: 17621265 2008
The association of Sam68 with Vav1 contributes to tumorigenesis.
Lazer G, Pe'er L, Schapira V, Richard S, Katzav S.
Cell Signal 19(12):2479-86. Epub 2007 Aug 8.PMID: 17855053 2007
Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.
Coyle JH, Guzik BW, Bor YC, Jin L, Eisner-Smerage L, Taylor SJ, Rekosh D, Hammarskjold ML.
Mol Cell Biol 23(1):92-103. 2003
The expression of Sam68, a protein involved in insulin signal transduction, is enhanced by insulin stimulation.
Sanchez-Margalet V, Gonzalez-Yanes C, Najib S, Fernandez-Santos JM, Martin-Lacave I.
Cell Mol Life Sci 60(4):751-8. 2003
Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1.
Cote J, Boisvert FM, Boulanger MC, Bedford MT, Richard S.
Mol Biol Cell 14(1):274-87. 2003
Sam68, the KH domain-containing superSTAR.
Lukong KE, Richard S.
Biochim Biophys Acta 1653(2):73-86. Review. 2003
Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K.
Yang JP, Reddy TR, Truong KT, Suhasini M, Wong-Staal F.
Oncogene 21(47):7187-94. 2002
Direct participation of Sam68, the 68-kilodalton Src-associated protein in mitosis, in the CRM1-mediated Rev nuclear export pathway.
Li J, Liu Y, Kim BO, He JJ.
J Virol 76(16):8374-82. 2002
Identification of cellular mRNA targets for RNA-binding protein Sam68.
Itoh M, Haga I, Li QH, Fujisawa J.
Nucleic Acids Res 30(24):5452-64. 2002
Signal-dependent regulation of splicing via phosphorylation of Sam68.
Matter N, Herrlich P, Konig H.
Nature 420(6916):691-5. 2002
Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.
Martin-Romero C, Sanchez-Margalet V.
Cell Immunol 212(2):83-91. 2001
Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling.
Sanchez-Margalet V, Najib S.
Mol Cell Endocrinol 183(1-2):113-21. 2001
Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains.
Bedford MT, Frankel A, Yaffe MB, Clarke S, Leder P, Richard S.
J Biol Chem 275(21):16030-6.PMID: 10748127 2000
Salpalpha and Salpbeta, growth-arresting homologs of Sam68.
Lee J, Burr JG.
Gene 240(1):133-47. 1999
A role for Sam68 in cell cycle progression antagonized by a spliced variantwithin the KH domain.
Barlat I, Maurier F, Duchesne M, Guitard E, Tocque B, Schweighoffer F.
J Biol Chem 272(6):3129-32. 1997
Molecular cloning and nucleic acid binding properties of the GAP-associatedtyrosine phosphoprotein p62.
Wong G, Muller O, Clark R, Conroy L, Moran MF, Polakis P, McCormick F.
Cell 69(3):551-8. 1992