| 1 | CD44, KHDRBS1, SND1
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| The transcriptional co-activator SND1 is a novel regulator of alternative splicing in prostate cancer cells.
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| Cappellari M, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Saarikettu J, Silvennoinen O, Sette C.
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| Oncogene 33(29):3794-802. doi: 10.1038/onc.2013.360. Epub 2013 Sep 2.
2014
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| 2 | IL2RA, KHDRBS1
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| Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells.
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| Fu K, Sun X, Zheng W, Wier EM, Hodgson A, Tran DQ, Richard S, Wan F.
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| Nat Commun 4:1909. doi: 10.1038/ncomms2916.
2013
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| 3 | IRS1, KHDRBS1
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| Sam68 interacts with IRS1.
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| Quintana-Portillo R, Canfrán-Duque A, Issad T, Sánchez-Margalet V, González-Yanes C.
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| Biochem Pharmacol 83(1):78-87. Epub 2011 Oct 10.
2012
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| 4 | KHDRBS1, OSTF1
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| Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.
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| Asbach B, Ludwig C, Saksela K, Wagner R.
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| PLoS One 7(6):e38540. doi: 10.1371/journal.pone.0038540. Epub 2012 Jun 20.
2012
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| 5 | KHDRBS1, MTOR
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| The Sam68 STAR RNA-binding protein regulates mTOR alternative splicing during adipogenesis.
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| Huot MÉ, Vogel G, Zabarauskas A, Ngo CT, Coulombe-Huntington J, Majewski J, Richard S.
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| Mol Cell 46(2):187-99. doi: 10.1016/j.molcel.2012.02.007. Epub 2012 Mar 15.
2012
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| 6 | KHDRBS1, NRXN1
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| SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.
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| Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S, Scheiffele P.
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| Cell 147(7):1601-14.
2011
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| 7 | KHDRBS1
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| Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor.
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| Ramakrishnan P, Baltimore D.
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| Mol Cell 43(2):167-79. Epub 2011 May 27.
2011
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| 8 | KHDRBS1
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| Met receptors induce Sam68-dependent cell migration by activation of alternate extracellular signal-regulated kinase family members.
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| Locatelli A, Lange CA.
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| J Biol Chem 286(24):21062-72. Epub 2011 Apr 13.
2011
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| 9 | KHDRBS1
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| Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.
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| Sánchez-Jiménez F, Pérez-Pérez A, González-Yanes C, Najib S, Varone CL, Sánchez-Margalet V.
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| Mol Cell Endocrinol 332(1-2):221-7. Epub 2010 Oct 28.
2011
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| 10 | KHDRBS1
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| Ablation of the Sam68 gene impairs female fertility and gonadotropin-dependent follicle development.
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| Bianchi E, Barbagallo F, Valeri C, Geremia R, Salustri A, De Felici M, Sette C.
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| Hum Mol Genet 19(24):4886-94. Epub 2010 Sep 29.
2010
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| 11 | KHDRBS1, SMN2
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| The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.
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| Pedrotti S, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Stamm S, Manley JL, Sette C.
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| EMBO J 29(7):1235-47. Epub 2010 Feb 25. 2010
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| 12 | FXTAS, KHDRBS1
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| Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients.
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| Sellier C, Rau F, Liu Y, Tassone F, Hukema RK, Gattoni R, Schneider A, Richard S, Willemsen R, Elliott DJ, Hagerman PJ, Charlet-Berguerand N.
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| EMBO J 29(7):1248-61. Epub 2010 Feb 25. 2010
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| 13 | KHDRBS1
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| Sam68 regulates a set of alternatively spliced exons during neurogenesis.
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| Chawla G, Lin CH, Han A, Shiue L, Ares M Jr, Black DL
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| Mol Cell Biol 29(1):201-13 2009
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| 14 | KHDRBS1, TIAL1
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| Sam68 relocalization into stress granules in response to oxidative stress through complexing with TIA-1.
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| Henao-Mejia J, He JJ.
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| Exp Cell Res 315(19):3381-95. Epub 2009 Jul 14.
2009
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| 15 | KHDRBS1
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| Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis.
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| Richard S, Vogel G, Huot ME, Guo T, Muller WJ, Lukong KE.
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| Oncogene 27(4):548-56. Epub 2007 Jul 9.PMID: 17621265 2008
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| 16 | KHDRBS1, VAV1
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| The association of Sam68 with Vav1 contributes to tumorigenesis.
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| Lazer G, Pe'er L, Schapira V, Richard S, Katzav S.
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| Cell Signal 19(12):2479-86. Epub 2007 Aug 8.PMID: 17855053 2007
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| 17 | KHDRBS1
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| Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.
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| Coyle JH, Guzik BW, Bor YC, Jin L, Eisner-Smerage L, Taylor SJ, Rekosh D, Hammarskjold ML.
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| Mol Cell Biol 23(1):92-103. 2003
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| 18 | KHDRBS1
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| The expression of Sam68, a protein involved in insulin signal transduction, is enhanced by insulin stimulation.
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| Sanchez-Margalet V, Gonzalez-Yanes C, Najib S, Fernandez-Santos JM, Martin-Lacave I.
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| Cell Mol Life Sci 60(4):751-8. 2003
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| 19 | KHDRBS1
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| Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1.
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| Cote J, Boisvert FM, Boulanger MC, Bedford MT, Richard S.
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| Mol Biol Cell 14(1):274-87. 2003
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| 20 | KHDRBS1
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| Sam68, the KH domain-containing superSTAR.
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| Lukong KE, Richard S.
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| Biochim Biophys Acta 1653(2):73-86. Review. 2003
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| 21 | KHDRBS1
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| Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K.
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| Yang JP, Reddy TR, Truong KT, Suhasini M, Wong-Staal F.
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| Oncogene 21(47):7187-94. 2002
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| 22 | KHDRBS1
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| Direct participation of Sam68, the 68-kilodalton Src-associated protein in mitosis, in the CRM1-mediated Rev nuclear export pathway.
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| Li J, Liu Y, Kim BO, He JJ.
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| J Virol 76(16):8374-82. 2002
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| 23 | KHDRBS1
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| Identification of cellular mRNA targets for RNA-binding protein Sam68.
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| Itoh M, Haga I, Li QH, Fujisawa J.
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| Nucleic Acids Res 30(24):5452-64. 2002
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| 24 | KHDRBS1
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| Signal-dependent regulation of splicing via phosphorylation of Sam68.
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| Matter N, Herrlich P, Konig H.
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| Nature 420(6916):691-5. 2002
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| 25 | KHDRBS1
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| Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.
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| Martin-Romero C, Sanchez-Margalet V.
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| Cell Immunol 212(2):83-91. 2001
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| 26 | KHDRBS1
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| Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling.
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| Sanchez-Margalet V, Najib S.
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| Mol Cell Endocrinol 183(1-2):113-21. 2001
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| 27 | FNBP4, KHDRBS1, WBP4
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| Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains.
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| Bedford MT, Frankel A, Yaffe MB, Clarke S, Leder P, Richard S.
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| J Biol Chem 275(21):16030-6.PMID: 10748127 2000
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| 28 | KHDRBS1, KHDRBS3
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| Salpalpha and Salpbeta, growth-arresting homologs of Sam68.
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| Lee J, Burr JG.
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| Gene 240(1):133-47. 1999
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| 29 | KHDRBS1
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| A role for Sam68 in cell cycle progression antagonized by a spliced variantwithin the KH domain.
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| Barlat I, Maurier F, Duchesne M, Guitard E, Tocque B, Schweighoffer F.
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| J Biol Chem 272(6):3129-32. 1997
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| 30 | KHDRBS1
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| Molecular cloning and nucleic acid binding properties of the GAP-associatedtyrosine phosphoprotein p62.
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| Wong G, Muller O, Clark R, Conroy L, Moran MF, Polakis P, McCormick F.
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| Cell 69(3):551-8. 1992
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