1 | KDM5A, KDM5B, KDM5C
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| Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.
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| Horton JR, Engstrom A, Zoeller EL, Liu X, Shanks JR, Zhang X, Johns MA, Vertino PM, Fu H, Cheng X.
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| J Biol Chem 291(6):2631-46. doi: 10.1074/jbc.M115.698449. Epub 2015 Dec 8.
2016
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2 | KDM5A
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| Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
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| Torres IO, Kuchenbecker KM, Nnadi CI, Fletterick RJ, Kelly MJ, Fujimori DG.
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| Nat Commun 6:6204. doi: 10.1038/ncomms7204.
2015
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3 | KDM5A, RB1
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| Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells.
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| Váraljai R, Islam AB, Beshiri ML, Rehman J, Lopez-Bigas N, Benevolenskaya EV.
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| Genes Dev 29(17):1817-34. doi: 10.1101/gad.264036.115. Epub 2015 Aug 27.
2015
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4 | KDM5A
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| Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
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| Torres IO, Kuchenbecker KM, Nnadi CI, Fletterick RJ, Kelly MJ, Fujimori DG.
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| Nat Commun 6:6204. doi: 10.1038/ncomms7204.
2015
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5 | CHD4, KDM5A
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| Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex.
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| Nishibuchi G, Shibata Y, Hayakawa T, Hayakawa N, Ohtani Y, Sinmyozu K, Tagami H, Nakayama J.
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| J Biol Chem 289(42):28956-70. doi: 10.1074/jbc.M114.573725. Epub 2014 Sep 4.
2014
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6 | KDM5A
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| Distinctive changes in histone H3K4 modification mediated via Kdm5a expression in spermatogonial stem cells of cryptorchid testes.
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| Nishio H, Hayashi Y, Moritoki Y, Kamisawa H, Mizuno K, Kojima Y, Kohri K.
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| J Urol 191(5 Suppl):1564-72. doi: 10.1016/j.juro.2013.10.071. Epub 2014 Mar 26.
2014
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7 | CCND1, CCNE1, KDM5A
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| Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.
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| Teng YC, Lee CF, Li YS, Chen YR, Hsiao PW, Chan MY, Lin FM, Huang HD, Chen YT, Jeng YM, Hsu CH, Yan Q, Tsai MD, Juan LJ.
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| Cancer Res 73(15):4711-21. doi: 10.1158/0008-5472.CAN-12-3165. Epub 2013 May 30.
2013
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8 | KDM5A, NUP98
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| NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern.
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| de Rooij JD, Hollink IH, Arentsen-Peters ST, van Galen JF, Berna Beverloo H, Baruchel A, Trka J, Reinhardt D, Sonneveld E, Zimmermann M, Alonzo TA, Pieters R, Meshinchi S, van den Heuvel-Eibrink MM, Zwaan CM.
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| Leukemia 27(12):2280-8. doi: 10.1038/leu.2013.87. Epub 2013 Mar 27.
2013
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9 | EP300, KDM5A, KDM6A, KDM6B, KLF4, POU5F1
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| The EP300, KDM5A, KDM6A and KDM6B chromatin regulators cooperate with KLF4 in the transcriptional activation of POU5F1.
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| Wang WP, Tzeng TY, Wang JY, Lee DC, Lin YH, Wu PC, Chen YP, Chiu IM, Chi YH.
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| PLoS One 7(12):e52556. doi: 10.1371/journal.pone.0052556. Epub 2012 Dec 18.
2012
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10 | KDM5A, KDM5B
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| H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence.
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| Chicas A, Kapoor A, Wang X, Aksoy O, Evertts AG, Zhang MQ, Garcia BA, Bernstein E, Lowe SW.
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| Proc Natl Acad Sci U S A 109(23):8971-6. doi: 10.1073/pnas.1119836109. Epub 2012 May 21.
2012
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11 | E2F4, KDM5A
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| Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation.
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| Beshiri ML, Holmes KB, Richter WF, Hess S, Islam AB, Yan Q, Plante L, Litovchick L, Gévry N, Lopez-Bigas N, Kaelin WG Jr, Benevolenskaya EV.
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| Proc Natl Acad Sci U S A 109(45):18499-504. doi: 10.1073/pnas.1216724109. Epub 2012 Oct 23.
2012
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12 | KDM5A, PER2
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| Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.
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| DiTacchio L, Le HD, Vollmers C, Hatori M, Witcher M, Secombe J, Panda S.
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| Science 333(6051):1881-5. 2011
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13 | KDM5A, RBPJ
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| Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex.
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| Liefke R, Oswald F, Alvarado C, Ferres-Marco D, Mittler G, Rodriguez P, Dominguez M, Borggrefe T.
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| Genes Dev 24(6):590-601.PMID: 20231316 2010
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14 | KDM5A, NUP98
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| Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
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| Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD.
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| Nature ature. 2009 May 10. [Epub ahead of print] 2009
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15 | BPTF, KDM5A
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| Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
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| Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD.
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| Nature 459(7248):847-51.
2009
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16 | KDM5A
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| The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif.
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| Tu S, Teng YC, Yuan C, Wu YT, Chan MY, Cheng AN, Lin PH, Juan LJ, Tsai MD.
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| Nat Struct Mol Biol 15(4):419-21. Epub 2008 Feb 12.
2008
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17 | KDM5A
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| RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.
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| Christensen J, Agger K, Cloos PA, Pasini D, Rose S, Sennels L, Rappsilber J, Hansen KH, Salcini AE, Helin K.
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| Cell 128(6):1063-76. Epub 2007 Feb 22. 2007
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18 | KDM5A, MORF4L1
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| RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.
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| Hayakawa T, Ohtani Y, Hayakawa N, Shinmyozu K, Saito M, Ishikawa F, Nakayama J.
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| Genes Cells 12(6):811-26. 2007
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19 | KDM5A, NUP98
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| Identification of NUP98 abnormalities in acute leukemia: JARID1A (12p13) as a new partner gene.
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| van Zutven LJ, Onen E, Velthuizen SC, van Drunen E, von Bergh AR, van den Heuvel-Eibrink MM, Veronese A, Mecucci C, Negrini M, de Greef GE, Beverloo HB.
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| Genes Chromosomes Cancer 45(5):437-46. 2006
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20 | KDM5A
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| Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription.
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| Chan SW, Hong W.
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| J Biol Chem 276(30):28402-12. Epub 2001 May 17.
2001
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21 | KDM5A, LMO2
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| T-cell oncogene rhombotin-2 interacts with retinoblastoma-binding protein 2.
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| Mao S, Neale GA, Goorha RM.
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| Oncogene 14(13):1531-9. 1997
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22 | BICD1, D12S1005, D12S889, D12S900, D12S927, KDM5A, SCNN1A
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| Isolation and regional assignment of human chromosome 12p cDNAs.
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| Baens M, et al.
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| Genomics 29 : 44-52. 1995
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23 | ARID4A, E2F1, KDM5A
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| Characterization of the retinoblastoma binding proteins RBP1 and RBP2.
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| Fattaey AR, Helin K, Dembski MS, Dyson N, Harlow E, Vuocolo GA, HanobikMG, Haskell KM, Oliff A, Defeo-Jones D, et al.
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| Oncogene 8(11):3149-56. 1993
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24 | KDM5A
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| Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product.
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| Defeo-Jones D, et al.
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| Nature 352 : 251-254. 1991
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