| 1 | KDM2A
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| SF-KDM2A binds to ribosomal RNA gene promoter, reduces H4K20me3 level, and elevates ribosomal RNA transcription in breast cancer cells.
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| Okamoto K, Tanaka Y, Tsuneoka M.
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| Int J Oncol nt J Oncol. 2017 Mar 10. doi: 10.3892/ijo.2017.3908. [Epub ahead of print]
2017
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| 2 | CBX5, KDM2A
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| KDM2A integrates DNA and histone modification signals through a CXXC/PHD module and direct interaction with HP1.
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| Borgel J, Tyl M, Schiller K, Pusztai Z, Dooley CM, Deng W, Wooding C, White RJ, Warnecke T, Leonhardt H, Busch-Nentwich EM, Bartke T.
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| Nucleic Acids Res ucleic Acids Res. 2016 Oct 24. pii: gkw979. [Epub ahead of print]
2016
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| 3 | KDM2A, SFRP2
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| Demethylation of SFRP2 by histone demethylase KDM2A regulated osteo-/dentinogenic differentiation of stem cells of the apical papilla.
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| Yu G, Wang J, Lin X, Diao S, Cao Y, Dong R, Wang L, Wang S, Fan Z.
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| Cell Prolif 49(3):330-40. doi: 10.1111/cpr.12256. Epub 2016 Apr 13.
2016
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| 4 | ATM, KDM2A
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| ATM-mediated KDM2A phosphorylation is required for the DNA damage repair.
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| Cao LL, Wei F, Du Y, Song B, Wang D, Shen C, Lu X, Cao Z, Yang Q, Gao Y, Wang L, Zhao Y, Wang H, Yang Y, Zhu WG.
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| Oncogene 35(3):402. doi: 10.1038/onc.2015.311. No abstract available.
2016
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| 5 | KDM2A, KDM5B
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| Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer.
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| Liu H, Liu L, Holowatyj A, Jiang Y, Yang ZQ.
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| Mol Carcinog ol Carcinog. 2015 Jul 24. doi: 10.1002/mc.22341. [Epub ahead of print]
2015
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| 6 | KDM2A
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| The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators.
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| Kawakami E, Tokunaga A, Ozawa M, Sakamoto R, Yoshida N.
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| Mech Dev 135:31-42. doi: 10.1016/j.mod.2014.10.001. Epub 2014 Oct 30.
2015
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| 7 | E2F1, KDM2A
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| Mammalian lysine histone demethylase KDM2A regulates E2F1-mediated gene transcription in breast cancer cells.
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| Rizwani W, Schaal C, Kunigal S, Coppola D, Chellappan S.
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| PLoS One 9(7):e100888. doi: 10.1371/journal.pone.0100888. eCollection 2014.
2014
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| 8 | KDM2A
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| Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells.
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| Dhar SS, Alam H, Li N, Wagner KW, Chung J, Ahn YW, Lee MG.
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| J Biol Chem 289(11):7483-96. doi: 10.1074/jbc.M113.521625. Epub 2014 Jan 30.
2014
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| 9 | EREG, KDM2A
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| Demethylation of epiregulin gene by histone demethylase FBXL11 and BCL6 corepressor inhibits osteo/dentinogenic differentiation.
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| Du J, Ma Y, Ma P, Wang S, Fan Z.
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| Stem Cells 31(1):126-36. doi: 10.1002/stem.1255.
2013
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| 10 | CDKN1B, CDKN2B, KDM2A
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| Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15INK4B and p27Kip1.
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| Gao R, Dong R, Du J, Ma P, Wang S, Fan Z.
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| Mol Cell Biochem 379(1-2):115-22. doi: 10.1007/s11010-013-1633-7. Epub 2013 Apr 5.
2013
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| 11 | KDM2A
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| Lysine-specific demethylase 2A (KDM2A) normalizes human embryonic stem cell derived keratinocytes.
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| Iuchi S, Green H.
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| Proc Natl Acad Sci U S A 109(24):9442-7. doi: 10.1073/pnas.1206176109. Epub 2012 May 25.
2012
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| 12 | KDM2A
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| JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation.
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| Tanaka Y, Okamoto K, Teye K, Umata T, Yamagiwa N, Suto Y, Zhang Y, Tsuneoka M.
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| EMBO J 29(9):1510-22. Epub 2010 Apr 8.PMID: 20379134 2010
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| 13 | CXXC1, KDM2A
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| CpG islands influence chromatin structure via the CpG-binding protein Cfp1.
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| Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr AR, Deaton A, Andrews R, James KD, Turner DJ, Illingworth R, Bird A.
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| Nature 464(7291):1082-6. 2010
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| 14 | KDM2A, NSD1
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| Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.
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| Lu T, Jackson MW, Wang B, Yang M, Chance MR, Miyagi M, Gudkov AV, Stark GR.
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| Proc Natl Acad Sci U S A 107(1):46-51. Epub 2009 Dec 22.PMID: 20080798 2010
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| 15 | KDM2A
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| Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB.
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| Lu T, Jackson MW, Singhi AD, Kandel ES, Yang M, Zhang Y, Gudkov AV, Stark GR.
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| Proc Natl Acad Sci U S A 106(38):16339-44. Epub 2009 Sep 1.PMID: 19805303 2009
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| 16 | KDM2A
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| KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state.
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| Frescas D, Guardavaccaro D, Kuchay SM, Kato H, Poleshko A, Basrur V, Elenitoba-Johnson KS, Katz RA, Pagano M.
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| Cell Cycle 7(22):3539-47. Epub 2008 Nov 24.PMID: 19001877 2008
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| 17 | KDM2A
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| Histone demethylation by a family of JmjC domain-containing proteins.
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| Tsukada Y, Fang J, Erdjument-Bromage H, Warren ME, Borchers CH, Tempst P, Zhang Y.
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| Nature 439(7078):811-6. Epub 2005 Dec 18.PMID: 16362057 2006
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| 18 | CCNF, FBXL12, FBXL6, FBXO10, FBXO11, FBXO18, FBXO2, FBXO3, FBXO4, FBXO8, FBXW5, FBXW5, FBXW7, FBXW8, KDM2A, SHFM3P1, SKP1, TSPAN17
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| A family of mammalian F-box proteins.
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| Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
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| Curr Biol 9(20):1180-2. 1999
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