| 1 | EIEE14, ENFL5, KCNT1
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| Human Slack Potassium Channel Mutations Increase Positive Cooperativity between Individual Channels.
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| Kim GE, Kronengold J, Barcia G, Quraishi IH, Martin HC, Blair E, Taylor JC, Dulac O, Colleaux L, Nabbout R, Kaczmarek LK.
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| Cell Rep 9(5):1661-72. doi: 10.1016/j.celrep.2014.11.015. Epub 2014 Dec 4.
2014
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| 2 | KCNT1
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| Disease-targeted sequencing of ion channel genes identifies de novo mutations in patients with non-familial Brugada syndrome.
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| Juang JM, Lu TP, Lai LC, Ho CC, Liu YB, Tsai CT, Lin LY, Yu CC, Chen WJ, Chiang FT, Yeh SF, Lai LP, Chuang EY, Lin JL.
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| Sci Rep 4:6733. doi: 10.1038/srep06733.
2014
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| 3 | KCNT1
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| Emerging role of the KCNT1 Slack channel in intellectual disability.
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| Kim GE, Kaczmarek LK.
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| Front Cell Neurosci 8:209. doi: 10.3389/fncel.2014.00209. eCollection 2014. Review.
2014
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| 4 | EIEE14, KCNT1
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| Identification of a novel de novo p.Phe932Ile KCNT1 mutation in a patient with leukoencephalopathy and severe epilepsy.
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| Vanderver A, Simons C, Schmidt JL, Pearl PL, Bloom M, Lavenstein B, Miller D, Grimmond SM, Taft RJ.
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| Pediatr Neurol 50(1):112-4. doi: 10.1016/j.pediatrneurol.2013.06.024. Epub 2013 Oct 10.
2014
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| 5 | EIEE14, KCNT1
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| A recurrent KCNT1 mutation in two sporadic cases with malignant migrating partial seizures in infancy.
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| Ishii A, Shioda M, Okumura A, Kidokoro H, Sakauchi M, Shimada S, Shimizu T, Osawa M, Hirose S, Yamamoto T.
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| Gene 531(2):467-71. doi: 10.1016/j.gene.2013.08.096. Epub 2013 Sep 10.
2013
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| 6 | ENFL5, KCNT1
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| Missense mutations in the sodium-gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsy.
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| Heron SE, Smith KR, Bahlo M, Nobili L, Kahana E, Licchetta L, Oliver KL, Mazarib A, Afawi Z, Korczyn A, Plazzi G, Petrou S, Berkovic SF, Scheffer IE, Dibbens LM.
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| Nat Genet 44(11):1188-90. doi: 10.1038/ng.2440. Epub 2012 Oct 21.
2012
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| 7 | EIEE14, KCNT1
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| De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy.
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| Barcia G, Fleming MR, Deligniere A, Gazula VR, Brown MR, Langouet M, Chen H, Kronengold J, Abhyankar A, Cilio R, Nitschke P, Kaminska A, Boddaert N, Casanova JL, Desguerre I, Munnich A, Dulac O, Kaczmarek LK, Colleaux L, Nabbout R.
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| Nat Genet 44(11):1255-9. doi: 10.1038/ng.2441. Epub 2012 Oct 21.
2012
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| 8 | INPP5J, KCNT1, KCNT2
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| PIP₂ modulation of Slick and Slack K⁺ channels.
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| de los Angeles Tejada M, Jensen LJ, Klaerke DA.
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| Biochem Biophys Res Commun 424(2):208-13. doi: 10.1016/j.bbrc.2012.06.038. Epub 2012 Jun 21.
2012
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| 9 | FMR1, KCNT1
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| Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.
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| Brown MR, Kronengold J, Gazula VR, Chen Y, Strumbos JG, Sigworth FJ, Navaratnam D, Kaczmarek LK.
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| Nat Neurosci 13(7):819-21. Epub 2010 May 30.PMID: 20512134 2010
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| 10 | KCNT1
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| cAMP-dependent kinase does not modulate the Slack sodium-activated potassium channel.
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| Nuwer MO, Picchione KE, Bhattacharjee A.
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| Neuropharmacology 57(3):219-26. Epub 2009 Jun 18.PMID: 19540251 2009
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| 11 | KCNT1, KCNT2
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| The N-terminal domain of Slack determines the formation and trafficking of Slick/Slack heteromeric sodium-activated potassium channels.
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| Chen H, Kronengold J, Yan Y, Gazula VR, Brown MR, Ma L, Ferreira G, Yang Y, Bhattacharjee A, Sigworth FJ, Salkoff L, Kaczmarek LK.
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| J Neurosci 29(17):5654-65.PMID: 19403831 2009
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| 12 | KCNT1, KCNT2
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| Slack and Slick KNa channels are required for the depolarizing afterpotential of acutely isolated, medium diameter rat dorsal root ganglion neurons.
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| Gao SB, Wu Y, Lü CX, Guo ZH, Li CH, Ding JP.
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| Acta Pharmacol Sin 29(8):899-905.PMID: 18664322 2008
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| 13 | KCNT1
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| The sodium-activated potassium channel Slack is modulated by hypercapnia and acidosis.
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| Ruffin VA, Gu XQ, Zhou D, Douglas RM, Sun X, Trouth CO, Haddad GG.
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| Neuroscience 151(2):410-8. Epub 2007 Nov 4.PMID: 18082331 2008
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| 14 | KCNT1, KCNT2
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| Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neurons.
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| Yang B, Desai R, Kaczmarek LK.
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| J Neurosci 27(10):2617-27.PMID: 17344399 2007
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| 15 | KCNT1, KCNT2
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| Opposite regulation of Slick and Slack K+ channels by neuromodulators.
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| Santi CM, Ferreira G, Yang B, Gazula VR, Butler A, Wei A, Kaczmarek LK, Salkoff L.
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| J Neurosci 26(19):5059-68.
2006
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| 16 | KCNT1
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| Slo2 sodium-activated K+ channels bind to the PDZ domain of PSD-95.
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| Uchino S, Wada H, Honda S, Hirasawa T, Yanai S, Nakamura Y, Ondo Y, Kohsaka S.
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| Biochem Biophys Res Commun 310(4):1140-7.PMID: 14559234 2003
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| 17 | KCNT1
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| Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels.
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| Gulbis JM, Zhou M, Mann S, MacKinnon R.
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| Science 289(5476):123-7. 2000
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| 18 | ALPK3, ARHGAP21, ARHGAP28, ASH1L, BOD1L, CASKIN1, CDH6, CGN, CHD7, COG1, CPSF2, CRAMP1L, DNAH1, EBF4, EIF2AK1, EIF2AK4, FAM135A, FAM63A, FBXO41, FBXO42, FGD6, FRMD4A, G2E3, HACE1, HEATR5B, HOMEZ, IBTK, IFT80, IGSF9, JMJD1C, KCNT1, KIAA1109, KIAA1328, KIAA1377, KIAA1383, KIAA1407, KIAA1430, KIF17, KLF17, KLHDC5, KLHL11, KLHL12, KLHL13, KLHL14, KLHL15, KLHL8, KLHL9, LRP2BP, LRRC7, MARCH4, MIB1, MRTFA, N4BP2, NFIA, NUFIP2, PCDH10, PDCD6IP, PDP2, PTCHD2, RBM27, RCOR3, RGAG1, RIC1, ROBO2, RPAP1, SEMA6A, SH3PXD2B, SIPA1L2, STAMBPL1, STARD9, TSR1, TULP4, TXNDC16, UPF2, WDFY1, WDR11, WDR35, ZMYM6, ZNF391, ZNF395, ZNF398, ZNF471, ZNF687, ZNFX1
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| Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O.
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| DNA Res 7(1):65-73. 2000
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