Citations for
1CRBN, KCNMA1
CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis.
Liu J, Ye J, Zou X, Xu Z, Feng Y, Zou X, Chen Z, Li Y, Cang Y.
Nat Commun 5:3924. doi: 10.1038/ncomms4924. 2014
2KCNMA1, LRRC26
LRRC26 is a Functional BK Channel Auxiliary γ Subunit in Arterial Smooth Muscle Cells.
Evanson K, Bannister JP, Leo MD, Jaggar JH.
Circ Res irc Res. 2014 Jun 6. pii: CIRCRESAHA.114.303407. [Epub ahead of print] 2014
3KCNJ2, KCNMA1, TRPV1
Identification of novel cholesterol-binding regions in Kir2 channels.
Rosenhouse-Dantsker A, Noskov S, Durdagi S, Logothetis DE, Levitan I.
J Biol Chem 288(43):31154-64. doi: 10.1074/jbc.M113.496117. Epub 2013 Sep 9. 2013
4KCNMA1
Properties of Slo1 K+ channels with and without the gating ring.
Budelli G, Geng Y, Butler A, Magleby KL, Salkoff L.
Proc Natl Acad Sci U S A 110(41):16657-62. doi: 10.1073/pnas.1313433110. Epub 2013 Sep 25. 2013
5KCNMA1, TMPRSS3
Tmprss3 loss of function impairs cochlear inner hair cell Kcnma1 channel membrane expression.
Molina L, Fasquelle L, Nouvian R, Salvetat N, Scott HS, Guipponi M, Molina F, Puel JL, Delprat B.
Hum Mol Genet 22(7):1289-99. doi: 10.1093/hmg/dds532. Epub 2012 Dec 18. 2013
6KCNMA1
BK channels mediate pathway-specific modulation of visual signals in the in vivo mouse retina.
Tanimoto N, Sothilingam V, Euler T, Ruth P, Seeliger MW, Schubert T.
J Neurosci 32(14):4861-6. doi: 10.1523/JNEUROSCI.4654-11.2012. 2012
7KCNMA1, RAB11B
The large conductance calcium-activated K(+) channel interacts with the small GTPase Rab11b.
Sokolowski S, Harvey M, Sakai Y, Jordan A, Sokolowski B.
Biochem Biophys Res Commun 426(2):221-5. doi: 10.1016/j.bbrc.2012.08.067. 2012
8KCNMA1
Alterations in membrane caveolae and BKCa channel activity in skin fibroblasts in Smith-Lemli-Opitz syndrome.
Ren G, Jacob RF, Kaulin Y, Dimuzio P, Xie Y, Mason RP, Tint GS, Steiner RD, Roullet JB, Merkens L, Whitaker-Menezes D, Frank PG, Lisanti MP, Cox RH, Tulenko TN.
Mol Genet Metab 104(3):346-55. doi: 10.1016/j.ymgme.2011.04.019. Epub 2011 May 27. 2011
9KCNMA1
Effects of insulin and high glucose on mobilization of slo1 BKCa channels in podocytes.
Kim EY, Dryer SE.
J Cell Physiol 226(9):2307-15. doi: 10.1002/jcp.22567. 2011
10KCNMA1, WNK4
WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism.
Zhuang J, Zhang X, Wang D, Li J, Zhou B, Shi Z, Gu D, Denson DD, Eaton DC, Cai H.
Am J Physiol Renal Physiol 301(2):F410-9. doi: 10.1152/ajprenal.00518.2010. Epub 2011 May 25. 2011
11KCNMA1
Modulation of BK channel gating by the 2 subunit involves both membrane-spanning and cytoplasmic domains of Slo1.
Lee US, Shi J, Cui J.
J Neurosci 30(48):16170-9. doi: 10.1523/JNEUROSCI.2323-10.2010. 2010
12KCNMA1
BK channels mediate cholinergic inhibition of high frequency cochlear hair cells.
Wersinger E, McLean WJ, Fuchs PA, Pyott SJ.
PLoS One 5(11):e13836. doi: 10.1371/journal.pone.0013836. 2010
13KCNMA1
Novel role of endothelial BKCa channels in altered vasoreactivity following hypoxia.
Hughes JM, Riddle MA, Paffett ML, Gonzalez Bosc LV, Walker BR.
Am J Physiol Heart Circ Physiol 299(5):H1439-50. doi: 10.1152/ajpheart.00124.2010. Epub 2010 Sep 3. 2010
14KCNMA1
The RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangements.
Yusifov T, Javaherian AD, Pantazis A, Gandhi CS, Olcese R.
J Gen Physiol 136(2):189-202. doi: 10.1085/jgp.200910374. Epub 2010 Jul 12. 2010
15KCNMA1
Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel.
Wu Y, Yang Y, Ye S, Jiang Y.
Nature 466(7304):393-7. doi: 10.1038/nature09252. Epub 2010 Jun 23. 2010
16KCNMA1
Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.
Hou S, Vigeland LE, Zhang G, Xu R, Li M, Heinemann SH, Hoshi T.
J Biol Chem 285(9):6434-42. doi: 10.1074/jbc.M109.069211. Epub 2009 Dec 26. 2010
17KCNMA1, MAGI1
MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface.
Ridgway LD, Kim EY, Dryer SE.
Am J Physiol Cell Physiol 297(1):C55-65. Epub 2009 Apr 29.PMID: 19403801 2009
18KCNMA1
Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block.
Carvacho I, Gonzalez W, Torres YP, Brauchi S, Alvarez O, Gonzalez-Nilo FD, Latorre R.
J Gen Physiol 131(2):147-61. 2008
19KCNMA1, CAV1
Slo1 caveolin-binding motif, a mechanism of caveolin-1-Slo1 interaction regulating Slo1 surface expression.
Alioua A, Lu R, Kumar Y, Eghbali M, Kundu P, Toro L, Stefani E.
J Biol Chem 283(8):4808-17. Epub 2007 Dec 12. 2008
20KCNMA1, NPHS1
Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface.
Kim EY, Choi KJ, Dryer SE.
Am J Physiol Renal Physiol 295(1):F235-46. Epub 2008 May 14. 2008
21KCNMA1
KCNMA1 gene amplification promotes tumor cell proliferation in human prostate cancer.
Bloch M, Ousingsawat J, Simon R, Schraml P, Gasser TC, Mihatsch MJ, Kunzelmann K, Bubendorf L.
Oncogene 26(17):2525-34. Epub 2006 Dec 4. 2007
22GEPD, KCNMA1
Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder.
Du W, Bautista JF, Yang H, Diez-Sampedro A, You SA, Wang L, Kotagal P, Luders HO, Shi J, Cui J, Richerson GB, Wang QK.
Nat Genet 37(7):733-8. Epub 2005 Jun 5. 2005
23CTNNA1, KCNMA1
The parent-of-origin effect of 10q22 in pre-eclamptic females coincides with two regions clustered for genes with down-regulated expression in androgenetic placentas.
Oudejans CB, Mulders J, Lachmeijer AM, van Dijk M, Konst AA, Westerman BA, van Wijk IJ, Leegwater PA, Kato HD, Matsuda T, Wake N, Dekker GA, Pals G, ten Kate LP, Blankenstein MA.
Mol Hum Reprod 10(8):589-98. Epub 2004 Jun 18. 2004
24KCNMA1
Acute activation of Maxi-K channels (hSlo) by estradiol binding to the beta subunit.
Valverde MA, Rojas P, Amigo J, Cosmelli D, Orio P, Bahamonde MI, Mann GE, Vergara C, Latorre R.
Science 285(5435):1929-31. 1999
25KCNMA1, KCNMB2
Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog.
Wallner M, Meera P, Toro L.
Proc Natl Acad Sci U S A 96(7):4137-42. 1999
26CLCN6, CLCN7, CLCN8, CLIC1, HTR3B, KCNAB1, KCNB1, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNMA1
Chromosomal localization of 15 ion channel genes.
Russell MWW, et al.
Somat Cell Mol Genet 22 : 425-431. 1996
27KCNMA1
Cloning and characterization of human and mouse homologs of the Drosophila calcium-activated potassium channel gene, slowpoke.
Pallanck L, et al.
Hum Mol Genet 3 : 1239-1243. 1994