| 1 | KCNK3, PPH4
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| An homozygous mutation in KCNK3 is associated with an aggressive form of hereditary pulmonary arterial hypertension.
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| Navas Tejedor P, Tenorio Castaño J, Palomino Doza J, Arias Lajara P, Gordo Trujillo G, López Meseguer M, Román Broto A, Lapunzina Abadía P, Escribano Subía P.
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| Clin Genet 91(3):453-457. doi: 10.1111/cge.12869.
2017
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| 2 | KCNK3
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| Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension.
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| Antigny F, Hautefort A, Meloche J, Belacel-Ouari M, Manoury B, Rucker-Martin C, Péchoux C, Potus F, Nadeau V, Tremblay E, Ruffenach G, Bourgeois A, Dorfmüller P, Breuils-Bonnet S, Fadel E, Ranchoux B, Jourdon P, Girerd B, Montani D, Provencher S, Bonnet S, Simonneau G, Humbert M, Perros F.
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| Circulation 133(14):1371-85. doi: 10.1161/CIRCULATIONAHA.115.020951.
2016
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| 3 | KCNK3, KCNK9
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| A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1.
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| Kilisch M, Lytovchenko O, Arakel EC, Bertinetti D, Schwappach B.
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| J Cell Sci 129(4):831-42. doi: 10.1242/jcs.180182.
2016
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| 4 | KCNK3
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| The K+ channel TASK1 modulates β-adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway.
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| Pisani DF, Beranger GE, Corinus A, Giroud M, Ghandour RA, Altirriba J, Chambard JC, Mazure NM, Bendahhou S, Duranton C, Michiels JF, Frontini A, Rohner-Jeanrenaud F, Cinti S, Christian M, Barhanin J, Amri EZ.
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| FASEB J 30(2):909-22. doi: 10.1096/fj.15-277475.
2016
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| 5 | KCNK3
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| TASK-1 Potassium Channels Limit Pancreatic α-Cell Calcium Influx and Glucagon Secretion.
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| Dadi PK, Luo B, Vierra NC, Jacobson DA.
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| Mol Endocrinol 29(5):777-87. doi: 10.1210/me.2014-1321.
2015
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| 6 | KCNK3, KCNK9
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| TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes.
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| Rinné S, Kiper AK, Schlichthörl G, Dittmann S, Netter MF, Limberg SH, Silbernagel N, Zuzarte M, Moosdorf R, Wulf H, Schulze-Bahr E, Rolfes C, Decher N.
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| J Mol Cell Cardiol 81:71-80. doi: 10.1016/j.yjmcc.2015.01.017.
2015
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| 7 | KCNK3, STX8
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| Cooperative endocytosis of the endosomal SNARE protein syntaxin-8 and the potassium channel TASK-1.
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| Renigunta V, Fischer T, Zuzarte M, Kling S, Zou X, Siebert K, Limberg MM, Rinné S, Decher N, Schlichthörl G, Daut J.
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| Mol Biol Cell 25(12):1877-91. doi: 10.1091/mbc.E13-10-0592.
2014
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| 8 | KCNK3
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| TASK-1 channels in oligodendrocytes: a role in ischemia mediated disruption.
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| Hawkins V, Butt A.
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| Neurobiol Dis 55:87-94. doi: 10.1016/j.nbd.2013.03.016.
2013
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| 9 | KCNK1, KCNK3, KCNK9
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| Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidification.
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| Ma L, Zhang X, Zhou M, Chen H.
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| J Biol Chem 287(44):37145-53. doi: 10.1074/jbc.M112.398164. Epub 2012 Sep 4.
2012
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| 10 | KCNK3, YWHAB
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| The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking.
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| Gabriel L, Lvov A, Orthodoxou D, Rittenhouse AR, Kobertz WR, Melikian HE.
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| J Biol Chem 287(39):32354-66.
2012
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| 11 | KCNK3
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| TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes.
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| Limberg SH, Netter MF, Rolfes C, Rinné S, Schlichthörl G, Zuzarte M, Vassiliou T, Moosdorf R, Wulf H, Daut J, Sachse FB, Decher N.
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| Cell Physiol Biochem 28(4):613-24. doi: 10.1159/000335757.
2011
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| 12 | KCNK3
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| Functional role of TASK-1 in the heart: studies in TASK-1-deficient mice show prolonged cardiac repolarization and reduced heart rate variability.
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| Donner BC, Schullenberg M, Geduldig N, Hüning A, Mersmann J, Zacharowski K, Kovacevic A, Decking U, Aller MI, Schmidt KG.
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| Basic Res Cardiol 106(1):75-87. doi: 10.1007/s00395-010-0128-x.
2011
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| 13 | CKMT1A, CKMT1B, KCNK3, UCP1
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| Gene expression in human brown adipose tissue.
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| Svensson PA, Jernås M, Sjöholm K, Hoffmann JM, Nilsson BE, Hansson M, Carlsson LM.
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| Int J Mol Med 27(2):227-32. doi: 10.3892/ijmm.2010.566. Epub 2010 Dec 1. 2011
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| 14 | KCNK3
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| Presence of nicotinic, purinergic and dopaminergic receptors and the TASK-1 K+-channel in the mouse carotid body.
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| Kåhlin J, Eriksson LI, Ebberyd A, Fagerlund MJ.
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| Respir Physiol Neurobiol 172(3):122-8. Epub 2010 May 7.PMID: 20452469 2010
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| 15 | KCNK3, KCNK9
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| TASK1 and TASK3 potassium channels: determinants of aldosterone secretion and adrenocortical zonation.
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| Bandulik S, Penton D, Barhanin J, Warth R.
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| Horm Metab Res 42(6):450-7. Epub 2010 Jan 4. Review.PMID: 20049674 2010
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| 16 | KCNK3, NOX4
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| Identification of subdomains in NADPH oxidase-4 critical for the oxygen-dependent regulation of TASK-1 K+ channels.
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| Park SJ, Chun YS, Park KS, Kim SJ, Choi SO, Kim HL, Park JW.
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| Am J Physiol Cell Physiol 297(4):C855-64. Epub 2009 Aug 5.PMID: 19657056 2009
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| 17 | KCNK3, KCNK9
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| Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons.
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| González JA, Jensen LT, Doyle SE, Miranda-Anaya M, Menaker M, Fugger L, Bayliss DA, Burdakov D.
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| Eur J Neurosci 30(1):57-64. Epub 2009 Jun 8.PMID: 19508695 2009
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| 18 | EDN1, KCNK3
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| Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells.
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| Tang B, Li Y, Nagaraj C, Morty RE, Gabor S, Stacher E, Voswinckel R, Weissmann N, Leithner K, Olschewski H, Olschewski A.
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| Am J Respir Cell Mol Biol 41(4):476-83. Epub 2009 Feb 2.PMID: 1918866 2009
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| 19 | KCNK3
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| The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice.
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| Meuth SG, Kleinschnitz C, Broicher T, Austinat M, Braeuninger S, Bittner S, Fischer S, Bayliss DA, Budde T, Stoll G, Wiendl H.
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| Neurobiol Dis 33(1):1-11. Epub 2008 Sep 30.PMID: 18930826 2009
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| 20 | KCNK3
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| Expression of TASK-1 in brainstem and the occurrence of central sleep apnea in rats.
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| Wang J, Zhang C, Li N, Su L, Wang G.
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| Respir Physiol Neurobiol 161(1):23-8. Epub 2007 Dec 23.PMID: 18272437 2008
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| 21 | KCNK3, KCNK9
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| TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity.
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| Mulkey DK, Talley EM, Stornetta RL, Siegel AR, West GH, Chen X, Sen N, Mistry AM, Guyenet PG, Bayliss DA.
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| J Neurosci 27(51):14049-58.PMID: 18094244 2007
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| 22 | KCNK3
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| Impact of TASK-1 in human pulmonary artery smooth muscle cells.
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| Olschewski A, Li Y, Tang B, Hanze J, Eul B, Bohle RM, Wilhelm J, Morty RE, Brau ME, Weir EK, Kwapiszewska G, Klepetko W, Seeger W, Olschewski H.
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| Circ Res 98(8):1072-80. Epub 2006 Mar 30. 2006
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| 23 | KCNK3
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| Impact of TASK-1 in human pulmonary artery smooth muscle cells.
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| Olschewski A, Li Y, Tang B, Hanze J, Eul B, Bohle RM, Wilhelm J, Morty RE, Brau ME, Weir EK, Kwapiszewska G, Klepetko W, Seeger W, Olschewski H.
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| Circ Res 98(8):1072-80. Epub 2006 Mar 30.PMID: 16574908 2006
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| 24 | KCNK2, KCNK3
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| Expression of TASK and TREK, two-pore domain K+ channels, in human myometrium.
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| Bai X, Bugg GJ, Greenwood SL, Glazier JD, Sibley CP, Baker PN, Taggart MJ, Fyfe GK.
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| Reproduction 129(4):525-30. 2005
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| 25 | KCNK3, KCNK2
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| Localization of TASK and TREK, two-pore domain K+ channels, in human cytotrophoblast cells.
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| Bai X, Greenwood SL, Glazier JD, Baker PN, Sibley CP, Taggart MJ, Fyfe GK.
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| J Soc Gynecol Investig 12(2):77-83. 2005
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| 26 | KCNK15, KCNK3, KCNK9
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| Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system.
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| Karschin C, Wischmeyer E, Preisig-Muller R, Rajan S, Derst C, Grzeschik KH, Daut J, Karschin A.
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| Mol Cell Neurosci 18(6):632-48. 2001
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| 27 | KCNK3
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| Assignment of the 2P domain, acid-sensitive potassium channel OAT1 gene KCNK3 to human chromosome bands 2p24.1-->p23.3 and murine 5B by in situ hybridization.
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| Manjunath NA, et al.
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| Cytogenet Cell Genet 86(3-4):242-243. No abstract available 1999
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| 28 | KCNK2, KCNK3
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| Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23.
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| Lesage F, et al.
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| Genomics 51 : 478-479. 1998
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| 29 | KCNK3
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| Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1).
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| Kim D, et al.
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| Circ Res 82(4):513-8 1998
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| 30 | KCNK3
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| TASK, a human background K+ channel to sense external pH variations near physiological pH.
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| Duprat F, et al.
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| EMBO J 16(17):5464-71 1997
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