| 1 | KCNJ6, KPLBS
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| Keppen-Lubinsky Syndrome Is Caused by Mutations in the Inwardly Rectifying K(+) Channel Encoded by KCNJ6.
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| Masotti A, Uva P, Davis-Keppen L, Basel-Vanagaite L, Cohen L, Pisaneschi E, Celluzzi A, Bencivenga P, Fang M, Tian M, Xu X, Cappa M, Dallapiccola B.
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| Am J Hum Genet 96(2):295-300. doi: 10.1016/j.ajhg.2014.12.011. Epub 2015 Jan 22.
2015
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| 2 | KCNJ6, SNX27
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| Sorting nexin 27 regulation of G protein-gated inwardly rectifying K⁺ channels attenuates in vivo cocaine response.
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| Munoz MB, Slesinger PA.
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| Neuron 82(3):659-69. doi: 10.1016/j.neuron.2014.03.011.
2014
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| 3 | KCNJ6
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| The K(+) channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia.
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| Nockemann D, Rouault M, Labuz D, Hublitz P, McKnelly K, Reis FC, Stein C, Heppenstall PA.
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| EMBO Mol Med 5(8):1263-77. doi: 10.1002/emmm.201201980. Epub 2013 Jul 1.
2013
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| 4 | KCNJ6
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| Differential maturation of GIRK2-expressing neurons in the mouse cerebellum.
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| Aguado C, Fernández-Alacid L, Cabañero MJ, Yanagawa Y, Schilling K, Watanabe M, Fritschy JM, Luján R.
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| J Chem Neuroanat 47:79-89. doi: 10.1016/j.jchemneu.2012.11.001. Epub 2012 Dec 20.
2013
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| 5 | KCNJ6
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| Conductance properties of the inwardly rectifying channel, Kir3.2: molecular and Brownian dynamics study.
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| Hilder TA, Chung SH.
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| Biochim Biophys Acta 1828(2):471-8. doi: 10.1016/j.bbamem.2012.09.022. Epub 2012 Sep 27.
2013
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| 6 | KCNJ6
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| GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area.
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| Reyes S, Fu Y, Double K, Thompson L, Kirik D, Paxinos G, Halliday GM.
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| J Comp Neurol 520(12):2591-607. doi: 10.1002/cne.23051.
2012
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| 7 | INPP5J, KCNJ6
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| Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium.
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| Whorton MR, MacKinnon R.
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| Cell 147(1):199-208.
2011
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| 8 | KCNJ6
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| Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/Kir3) channel subunits in the brain.
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| Fernández-Alacid L, Watanabe M, Molnár E, Wickman K, Luján R.
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| Eur J Neurosci 34(11):1724-36. doi: 10.1111/j.1460-9568.2011.07886.x. Epub 2011 Nov 18.
2011
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| 9 | KCNJ6
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| Sperm GIRK2-containing K+ inward rectifying channels participate in sperm capacitation and fertilization.
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| Yi YJ, Sung DY, Millette C, Sutovsky M, Kennedy C, Sutovsky P, Thompson W, Thomas K.
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| Syst Biol Reprod Med 57(6):296-308. doi: 10.3109/19396368.2011.631685. Epub 2011 Nov 7.
2011
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| 10 | KCNJ5, KCNJ6, KCNJ9
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| Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.
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| Lu Q, Gong L, Xu H, Zhang T, Yan X, Zhao J, Zhang Z, Wang Y, Han Y.
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| Mol Med Rep 4(5):941-5. doi: 10.3892/mmr.2011.499. Epub 2011 May 31.
2011
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| 11 | DEL21QD, DYRK1A, KCNJ6
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| Clinical manifestations of the deletion of Down syndrome critical region including DYRK1A and KCNJ6.
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| Yamamoto T, Shimojima K, Nishizawa T, Matsuo M, Ito M, Imai K.
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| Am J Med Genet A m J Med Genet A. 2010 Dec 10. [Epub ahead of print]PMID: 21154855 2010
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| 12 | GABRB1, KCNJ6
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| GABAB-GIRK2-mediated signaling in Down syndrome.
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| Cramer NP, Best TK, Stoffel M, Siarey RJ, Galdzicki Z.
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| Adv Pharmacol 58:397-426. doi: 10.1016/S1054-3589(10)58015-3. Review.
2010
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| 13 | KCNJ3, KCNJ5, KCNJ6, KCNJ9
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| G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation.
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| Chung HJ, Ge WP, Qian X, Wiser O, Jan YN, Jan LY.
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| Proc Natl Acad Sci U S A 106(2):635-40. Epub 2008 Dec 31.
2009
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| 14 | GNB1, GNB2, GNB3, KCNJ6
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| Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels.
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| Chung HJ, Qian X, Ehlers M, Jan YN, Jan LY.
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| Proc Natl Acad Sci U S A 106(2):629-34. doi: 10.1073/pnas.0811615106. Epub 2008 Dec 31.
2009
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| 15 | KCNJ6
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| Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain.
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| Saenz del Burgo L, Cortes R, Mengod G, Zarate J, Echevarria E, Salles J.
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| J Comp Neurol 510(6):581-606.
2008
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| 16 | KCNJ6
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| Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels.
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| Inanobe A, Matsuura T, Nakagawa A, Kurachi Y.
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| Channels (Austin) 1(1):39-45. Epub 2007 Jan 16.
2007
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| 17 | KCNJ6, TAB1, XIAP
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| XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization.
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| Lu M, Lin SC, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J, Wu H.
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| Mol Cell 26(5):689-702. 2007
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| 18 | KCNJ3, KCNJ5, KCNJ6
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| Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.
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| Shankar H, Murugappan S, Kim S, Jin J, Ding Z, Wickman K, Kunapuli SP.
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| Blood 104(5):1335-43. Epub 2004 May 13.
2004
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| 19 | KCNJ3, KCNJ6
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| Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel.
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| Ivanina T, Rishal I, Varon D, Mullner C, Frohnwieser-Steinecke B, Schreibmayer W, Dessauer CW, Dascal N.
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| J Biol Chem 278(31):29174-83. Epub 2003 May 12. 2003
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| 20 | KCNJ3, KCNJ6
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| Mutation analysis of the inwardly rectifying K(+) channels KCNJ6 (GIRK2) and KCNJ3 (GIRK1) in juvenile myoclonic epilepsy.
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| Hallmann K, Durner M, Sander T, Steinlein OK.
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| Am J Med Genet 96(1):8-11 2000
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| 21 | DYRK1A, HLCS, KCNJ6, TTC1
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| Gene identification in 1.6-Mb region of the Down syndrome region on chromosome 21.
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| Ohira M, et al.
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| Genome Res 7 : 47-58. 1997
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| 22 | TTC3, RCAN1, DYRK1A, KCNJ6
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| Cosmid contig and transcriptional map of three regions of human chromosome 21q22: identification of 37 novel transcripts by direct selection.
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| Guimera J, Pucharcos C, Domenech A, Casas C, Solans A, Gallardo T, Ashley J, Lovett M, Estivill X, Pritchard M.
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| Genomics 45(1):59-67. 1997
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| 23 | KCNJ6
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| A human pancreatic islet inwardly rectifying potassium channel : cDNA cloning, determination of the genomic structure and genetic variations in Japanese NIDDM patients.
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| Tanizawa Y, et al.
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| Diabetologia 39 : 447-452. 1996
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| 24 | KCNJ6
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| The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2.
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| Tong Y, et al.
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| FEBS Lett 390 : 63-68. 1996
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| 25 | KCNJ6
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| Characterization and variation of a human inwardly-rectifying K-channel gene (KCNJ6) : a putative ATP-sensitive K-channel subunit.
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| Sakura H, et al.
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| FEBS Lett 367 : 193-197. 1995
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| 26 | KCNJ6
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| Isolation of a cDNA clone encoding a K ATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM.
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| Tsaur ML, et al.
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| Diabetes 44 : 592-596. 1995
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| 27 | KCNJ6, C5AR1
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| Human C5a anaphylatoxin : gene cloning and expression in Escherichia coli.
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| Bautsch W, et al.
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| Immunobiology 185 : 41-52. 1992
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