1 | KCNA3
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| N-glycosylation promotes the cell surface expression of Kv1.3 potassium channels.
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| Zhu J, Yan J, Thornhill WB.
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| FEBS J 279(15):2632-44. doi: 10.1111/j.1742-4658.2012.08642.x. Epub 2012 Jun 15.
2012
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2 | KCNA3
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| Kv1.3 channels can modulate cell proliferation during phenotypic switch by an ion-flux independent mechanism.
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| Cidad P, Jiménez-Pérez L, García-Arribas D, Miguel-Velado E, Tajada S, Ruiz-McDavitt C, López-López JR, Pérez-García MT.
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| Arterioscler Thromb Vasc Biol 32(5):1299-307. doi: 10.1161/ATVBAHA.111.242727. Epub 2012 Mar 1.
2012
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3 | KCNA3
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| Modulation of Kv1.3 channels by protein kinase A I in T lymphocytes is mediated by the disc large 1-tyrosine kinase Lck complex.
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| Kuras Z, Kucher V, Gordon SM, Neumeier L, Chimote AA, Filipovich AH, Conforti L.
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| Am J Physiol Cell Physiol 302(10):C1504-12. doi: 10.1152/ajpcell.00263.2011. Epub 2012 Feb 29.
2012
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4 | KCNA3
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| Kv1.3 channels as a potential target for immunomodulation of CD4+ CD28null T cells in patients with acute coronary syndrome.
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| Xu R, Cao M, Wu X, Wang X, Ruan L, Quan X, Lü C, He W, Zhang C.
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| Clin Immunol 142(2):209-17. doi: 10.1016/j.clim.2011.10.009. Epub 2011 Nov 9.
2012
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5 | KCNA3
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| Disruption of kv1.3 channel forward vesicular trafficking by hypoxia in human T lymphocytes.
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| Chimote AA, Kuras Z, Conforti L.
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| J Biol Chem 287(3):2055-67. doi: 10.1074/jbc.M111.274209. Epub 2011 Nov 30.
2012
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6 | KCNA3
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| A C-terminal PDZ binding domain modulates the function and localization of Kv1.3 channels.
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| Doczi MA, Damon DH, Morielli AD.
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| Exp Cell Res 317(16):2333-41. doi: 10.1016/j.yexcr.2011.06.009. Epub 2011 Jun 25.
2011
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7 | KCNA3, KCNE2, KCNQ1
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| KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.
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| Roepke TK, Kanda VA, Purtell K, King EC, Lerner DJ, Abbott GW.
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| FASEB J 25(12):4264-73. doi: 10.1096/fj.11-187609. Epub 2011 Aug 22.
2011
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8 | KCNA3
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| Kv1.3 channels regulate synaptic transmission in the nucleus of solitary tract.
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| Ramirez-Navarro A, Glazebrook PA, Kane-Sutton M, Padro C, Kline DD, Kunze DL.
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| J Neurophysiol 105(6):2772-80. doi: 10.1152/jn.00494.2010. Epub 2011 Mar 23.
2011
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9 | KCNA3
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| Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers.
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| Cheong A, Li J, Sukumar P, Kumar B, Zeng F, Riches K, Munsch C, Wood IC, Porter KE, Beech DJ.
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| Cardiovasc Res 89(2):282-9. doi: 10.1093/cvr/cvq305. Epub 2010 Sep 29.
2011
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10 | KCNA3, KCNA5
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| Voltage-dependent potassium channels Kv1.3 and Kv1.5 in human fetus.
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| Bielanska J, Hernández-Losa J, Moline T, Somoza R, Ramón Y Cajal S, Condom E, Ferreres JC, Felipe A.
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| Cell Physiol Biochem 26(2):219-26. doi: 10.1159/000320528. Epub 2010 Aug 24.
2010
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11 | KCNA3
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| Localization of Kv1.3 channels in presynaptic terminals of brainstem auditory neurons.
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| Gazula VR, Strumbos JG, Mei X, Chen H, Rahner C, Kaczmarek LK.
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| J Comp Neurol 518(16):3205-20. doi: 10.1002/cne.22393.
2010
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12 | KCNA3
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| Kv1.3 is the exclusive voltage-gated K+ channel of platelets and megakaryocytes: roles in membrane potential, Ca2+ signalling and platelet count.
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| McCloskey C, Jones S, Amisten S, Snowden RT, Kaczmarek LK, Erlinge D, Goodall AH, Forsythe ID, Mahaut-Smith MP.
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| J Physiol 588(Pt 9):1399-406. doi: 10.1113/jphysiol.2010.188136. Epub 2010 Mar 22.
2010
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13 | KCNA3
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| Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes.
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| Gulbins E, Sassi N, Grassmč H, Zoratti M, Szabň I.
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| Biochim Biophys Acta 1797(6-7):1251-9. doi: 10.1016/j.bbabio.2010.01.018. Epub 2010 Jan 28.
2010
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14 | KCNA3
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| Localization of Kv1.3 channels in the immunological synapse modulates the calcium response to antigen stimulation in T lymphocytes.
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| Nicolaou SA, Neumeier L, Steckly A, Kucher V, Takimoto K, Conforti L.
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| J Immunol 183(10):6296-302. doi: 10.4049/jimmunol.0900613. Epub 2009 Oct 19.
2009
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15 | KCNA3
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| Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse.
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| Tóth A, Szilágyi O, Krasznai Z, Panyi G, Hajdú P.
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| Immunol Lett 125(1):15-21. doi: 10.1016/j.imlet.2009.05.004. Epub 2009 May 27.
2009
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16 | BAX, KCNA3
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| Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes.
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| Szabó I, Bock J, Grassmé H, Soddemann M, Wilker B, Lang F, Zoratti M, Gulbins E.
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| Proc Natl Acad Sci U S A 105(39):14861-6. Epub 2008 Sep 25.
2008
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17 | KCNA3
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| Kv1.3 channels in postganglionic sympathetic neurons: expression, function, and modulation.
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| Doczi MA, Morielli AD, Damon DH.
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| Am J Physiol Regul Integr Comp Physiol 295(3):R733-40. doi: 10.1152/ajpregu.00077.2008. Epub 2008 Jul 9.
2008
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18 | KCNA3, KCNA5
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| Kv1.5 association modifies Kv1.3 traffic and membrane localization.
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| Vicente R, Villalonga N, Calvo M, Escalada A, Solsona C, Soler C, Tamkun MM, Felipe A.
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| J Biol Chem 283(13):8756-64. doi: 10.1074/jbc.M708223200. Epub 2008 Jan 24.
2008
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19 | KCNA3
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| Characterization of the functional properties of the voltage-gated potassium channel Kv1.3 in human CD4+ T lymphocytes.
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| Hu L, Pennington M, Jiang Q, Whartenby KA, Calabresi PA.
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| J Immunol 179(7):4563-70.
2007
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20 | KCNA3
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| Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.
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| Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, Kolski-Andreaco A, Wei E, Grino A, Counts DR, Wang PH, LeeHealey CJ, S Andrews B, Sankaranarayanan A, Homerick D, Roeck WW, Tehranzadeh J, Stanhope KL, Zimin P, Havel PJ, Griffey S, Knaus HG, Nepom GT, Gutman GA, Calabresi PA, Chandy KG.
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| Proc Natl Acad Sci U S A 103(46):17414-9. Epub 2006 Nov 6. 2006
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21 | KCNA3
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| The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity.
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| Xu J, Wang P, Li Y, Li G, Kaczmarek LK, Wu Y, Koni PA, Flavell RA, Desir GV.
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| Proc Natl Acad Sci U S A 101(9):3112-7. Epub 2004 Feb 23. 2004
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22 | KCNA3
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| The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight.
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| Xu J, Koni PA, Wang P, Li G, Kaczmarek L, Wu Y, Li Y, Flavell RA, Desir GV.
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| Hum Mol Genet 12(5):551-9. 2003
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23 | KCNA3
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| Confirmation of the assignment of the gene encoding Kv1.3, a voltage-gated potassium channel (KCNA3) to the proximal short arm of human chromosome 1.
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| Folander K, et al.
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| Genomics 23 : 295-296. 1994
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24 | KCNA3
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| Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.
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| Attali B, et al.
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| J Biol Chem 267 : 8650-8657. 1992
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25 | KCNA3, KCNA5
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| Expression and chromosomal localization of a lymphocyte K+ channel gene.
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| Grissmer S, et al.
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| Proc Natl Acad Sci U S A 87 : 9411-9415. 1990
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