Citations for
1KAT2A, KAT2B
Kat2a and Kat2b Acetyltransferase Activity Regulates Craniofacial Cartilage and Bone Differentiation in Zebrafish and Mice.
Sen R, Pezoa SA, Carpio Shull L, Hernandez-Lagunas L, Niswander LA, Artinger KB.
J Dev Biol 6(4). pii: E27. doi: 10.3390/jdb6040027. 2018
2KAT2A, KAT2B, PLK4
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.
Fournier M, Orpinell M, Grauffel C, Scheer E, Garnier JM, Ye T, Chavant V, Joint M, Esashi F, Dejaegere A, Gönczy P, Tora L.
Nat Commun 7:13227. doi: 10.1038/ncomms13227. 2016
3BID, KAT2B, TADA3
A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage.
Brasacchio D, Noori T, House C, Brennan AJ, Simpson KJ, Susanto O, Bird PI, Johnstone RW, Trapani JA.
Cell Death Differ 21(5):748-60. doi: 10.1038/cdd.2013.203. Epub 2014 Jan 24. 2014
4EP300, HDAC6, KAT2B, TRIM50
HDAC6 mediates the acetylation of TRIM50.
Fusco C, Micale L, Augello B, Mandriani B, Pellico MT, De Nittis P, Calcagně A, Monti M, Cozzolino F, Pucci P, Merla G.
Cell Signal 26(2):363-9. doi: 10.1016/j.cellsig.2013.11.036. 2014
5KAT2B, RUNX2
PCAF acetylates Runx2 and promotes osteoblast differentiation.
Wang CY, Yang SF, Wang Z, Tan JM, Xing SM, Chen DC, Xu SM, Yuan W.
J Bone Miner Metab Bone Miner Metab. 2013 Mar 7. [Epub ahead of print] 2013
6KAT2B, MAPRE1, MTUS2
EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.
Xia P, Wang Z, Liu X, Wu B, Wang J, Ward T, Zhang L, Ding X, Gibbons G, Shi Y, Yao X.
Proc Natl Acad Sci U S A 109(41):16564-9. doi: 10.1073/pnas.1202639109. Epub 2012 Sep 21. 2012
7KAT2B
p300/CBP-associated factor selectively regulates the extinction of conditioned fear.
Wei W, Coelho CM, Li X, Marek R, Yan S, Anderson S, Meyers D, Mukherjee C, Sbardella G, Castellano S, Milite C, Rotili D, Mai A, Cole PA, Sah P, Kobor MS, Bredy TW.
J Neurosci 32(35):11930-41. 2012
8KAT2B
The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.
Love IM, Sekaric P, Shi D, Grossman SR, Androphy EJ.
Cell Cycle 11(13):2458-66. doi: 10.4161/cc.20864. Epub 2012 Jul 1. 2012
9CDKN1B, KAT2B
PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1.
Pérez-Luna M, Aguasca M, Perearnau A, Serratosa J, Martínez-Balbas M, Jesús Pujol M, Bachs O.
Nucleic Acids Res 40(14):6520-33. doi: 10.1093/nar/gks343. Epub 2012 Apr 29. 2012
10KAT2B
Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies.
Pons D, Trompet S, de Craen AJ, Thijssen PE, Quax PH, de Vries MR, Wierda RJ, van den Elsen PJ, Monraats PS, Ewing MM, Heijmans BT, Slagboom PE, Zwinderman AH, Doevendans PA, Tio RA, de Winter RJ, de Maat MP, Iakoubova OA, Sattar N, Shepherd J, Westendorp RG, Jukema JW; PROSPER study group; WOSCOPS study group; GENDER study group.
Heart 97(2):143-50. doi: 10.1136/hrt.2010.199927. Epub 2010 Nov 8. 2011
11KAT2B, KAT5B
Parathyroid hormone activation of matrix metalloproteinase-13 transcription requires the histone acetyltransferase activity of p300 and PCAF and p300-dependent acetylation of PCAF.
Lee M, Partridge NC.
J Biol Chem 285(49):38014-22. doi: 10.1074/jbc.M110.142141. Epub 2010 Sep 24. 2010
12KAT2B
Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway.
Perez RE, Knights CD, Sahu G, Catania J, Kolukula VK, Stoler D, Graessmann A, Ogryzko V, Pishvaian M, Albanese C, Avantaggiati ML.
J Cell Physiol 225(2):394-405. doi: 10.1002/jcp.22285. 2010
13ESRRA, KAT2B
An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha.
Wilson BJ, Tremblay AM, Deblois G, Sylvain-Drolet G, Gigučre V.
Mol Endocrinol 24(7):1349-58. doi: 10.1210/me.2009-0441. Epub 2010 May 19. 2010
14KAT2B, KLF8
KLF8 recruits the p300 and PCAF co-activators to its amino terminal activation domain to activate transcription.
Urvalek AM, Wang X, Lu H, Zhao J.
Cell Cycle 9(3):601-11. 2010
15KAT2B
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis
Gamper AM, Kim J, Roeder RG.
Mol Cell Biol. 29(1):266-80 2009
16KAT2B
Multiple lysine methylation of PCAF by Set9 methyltransferase
Masatsugu T, Yamamoto K.
Biochem. Biophys. Res. Commun. 381(1):22-6 2009
17KAT2B
Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma.
Zhu C, Qin YR, Xie D, Chua DT, Fung JM, Chen L, Fu L, Hu L, Guan XY.
Oncogene 28(31):2821-8. Epub 2009 Jun 15. 2009
18CDK2, KAT2B
The transcriptional co-activator PCAF regulates cdk2 activity.
Mateo F, Vidal-Laliena M, Canela N, Zecchin A, Martínez-Balbás M, Agell N, Giacca M, Pujol MJ, Bachs O.
Nucleic Acids Res 37(21):7072-84. doi: 10.1093/nar/gkp777. Epub . 2009
19FOXM1, KAT2B
Cyclin E/Cdk2, P/CAF, and E1A regulate the transactivation of the c-myc promoter by FOXM1.
Wierstra I, Alves J.
Biochem Biophys Res Commun 368(1):107-15. Epub 2008 Jan 17. 2008
20BCR, BIRC2, DFFA, KAT2B
GCN5 and BCR signalling collaborate to induce pre-mature B cell apoptosis through depletion of ICAD and IAP2 and activation of caspase activities.
Kikuchi H, Nakayama T.
Gene 419(1-2):48-55. Epub 2008 May 3. 2008
21CCDC101, KAT2B, YEATS2
Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
Wang YL, Faiola F, Xu M, Pan S, Martinez E.
J Biol Chem 283(49):33808-15. Epub 2008 Oct 6. 2008
22KAT2B
p300 is required for orderly G1/S transition in human cancer cells.
Iyer NG, Xian J, Chin SF, Bannister AJ, Daigo Y, Aparicio S, Kouzarides T, Caldas C.
Oncogene 26(1):21-9. Epub 2006 Jul 31. 2007
23ATF4, DDIT3, KAT2B
The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP.
Cherasse Y, Maurin AC, Chaveroux C, Jousse C, Carraro V, Parry L, Deval C, Chambon C, Fafournoux P, Bruhat A.
Nucleic Acids Res 35(17):5954-65. Epub 2007 Aug 28. 2007
24DEK, EP300, KAT2B
Regulation of histone acetyltransferase activity of p300 and PCAF by proto-oncogene protein DEK.
Ko SI, Lee IS, Kim JY, Kim SM, Kim DW, Lee KS, Woo KM, Baek JH, Choo JK, Seo SB.
FEBS Lett 580(13):3217-22. Epub 2006 May 4. 2006
25KAT2B
PCAF modulates PTEN activity
Okumura, K.; Mendoza, M.; Bachoo, R. M.; DePinho, R. A.; Cavenee, W. K.; Furnari, F. B.
J. Biol. Chem. 281: 26562-26568 2006
26ATXN7, CRX, KAT2B, SCA7, SUPT3H, TAF9
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.
Palhan VB, Chen S, Peng GH, Tjernberg A, Gamper AM, Fan Y, Chait BT, La Spada AR, Roeder RG.
Proc Natl Acad Sci U S A 102(24):8472-7. Epub 2005 Jun 2. 2005
27CREBBP, IVL, KAT2B
Regulation of the human involucrin gene promoter by co-activator proteins.
Tran NQ, Crowe DL.
Biochem J 381(Pt 1):267-73. 2004
28ATRX, DNMT1, DNMT3B, HDAC1, HDAC2, KAT2B, KAT8, MBD1, MBD2, MECP2, SIN3A
Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.
Craig JM, Earle E, Canham P, Wong LH, Anderson M, Choo KH.
Hum Mol Genet 12(23):3109-21. Epub 2003 Sep 30. 2003
29KAT2B, TP73
PCAF is a coactivator for p73-mediated transactivation.
Zhao LY, Liu Y, Bertos NR, Yang XJ, Liao D.
Oncogene 22(51):8316-29. 2003
30KAT2B
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.
Demarest SJ, Martinez-Yamout M, Chung J, Chen H, Xu W, Dyson HJ, Evans RM, Wright PE.
Nature 415(6871):549-53. 2002
31KAT2B
Possible role of transcriptional coactivator P/CAF and nuclear acetylation in calcium-induced keratinocyte differentiation.
Kawabata H, Kawahara K, Kanekura T, Araya N, Daitoku H, Hatta M, Miura N, Fukamizu A, Kanzaki T, Maruyama I, Nakajima T.
J Biol Chem 277(10):8099-105. 2002
32KAT2A, KAT2B, SUPT3H, SUPT7L, TADA1, TAF9
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG.
Mol Cell Biol 21(20):6782-95.PMID: 11564863 2001
33KAT2B, TAL1
P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL.
Huang S, Qiu Y, Shi Y, Xu Z, Brandt SJ.
EMBO J 19(24):6792-6803. 2000
34EP300, KAT2B, TWIST1
Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A.
Hamamori Y, et al.
Cell 96 : 405-413. 1999
35KAT2B
Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program.
Sartorelli V, Puri PL, Hamamori Y, Ogryzko V, Chung G, Nakatani Y, Wang JY, Kedes L.
Mol Cell 4(5):725-34. 1999
36KAT2B
Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program
Sartorelli, V.; Puri, P. L.; Hamamori, Y.; Ogryzko, V.; Chung, G.; Nakatani, Y.; Wang, J. Y. J.; Kedes, L.
Molec. Cell 4: 725-734 1999
37HDAC1, HDAC2, HDAC3, KAT2A, KAT2B
Identification and mapping of human histone acetylation modifier gene homologues.
Randhawa GS, et al.
Genomics 51 : 262-269. 1998
38KAT2B
Long-distance transcriptional enhancement by the histone acetyltransferase PCAF.
Krumm A, et al.
Proc Natl Acad Sci U S A 95 : 13501-13506. 1998
39GCN5, KAT2A, KAT2B
Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates.
Xu W, Edmondson DG, Roth SY.
Mol Cell Biol 18(10):5659-69. 1998
40KAT2B
A p300/CBP-associated factor that completes with the adenoviral oncoprotein E1A.
Yang XJ, et al.
Nature 382 : 319-324. 1996
41KAT2B
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.
Nature 382(6589):319-24. 1996
42KAT2A, KAT2B
Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription.
Georgakopoulos T, et al.
EMBO J 11 : 4145-4152. 1992