Citations for
1DSC3, DSP, JUP, SOX30
SOX30 is a key regulator of desmosomal gene suppressing tumor growth and metastasis in lung adenocarcinoma.
Hao X, Han F, Ma B, Zhang N, Chen H, Jiang X, Yin L, Liu W, Ao L, Cao J, Liu J.
J Exp Clin Cancer Res 37(1):111. doi: 10.1186/s13046-018-0778-3. 2018
2DSC2, DSC3, JUP, LEF1
Plakoglobin as a regulator of desmocollin gene expression.
Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Műller EJ, Koch PJ.
J Invest Dermatol 133(12):2732-2740. doi: 10.1038/jid.2013.220. Epub 2013 May 7. 2013
3ARVDPPK, JUP
Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy.
Li D, Liu Y, Maruyama M, Zhu W, Chen H, Zhang W, Reuter S, Lin SF, Haneline LS, Field LJ, Chen PS, Shou W.
Hum Mol Genet 20(23):4582-96. doi: 10.1093/hmg/ddr392. Epub 2011 Aug 31. 2011
4DPAGT1, JUP
N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway.
Sengupta PK, Bouchie MP, Kukuruzinska MA.
J Biol Chem 285(41):31164-73. Epub 2010 Aug 6. 2010
5ARVDPPK, JUP
Homozygous mutations in the 5' region of the JUP gene result in cutaneous disease but normal heart development in children.
Cabral RM, Liu L, Hogan C, Dopping-Hepenstal PJ, Winik BC, Asial RA, Dobson R, Mein CA, Baselaga PA, Mellerio JE, Nanda A, Boente Mdel C, Kelsell DP, McGrath JA, South AP.
J Invest Dermatol 130(6):1543-50. Epub 2010 Feb 4. 2010
6ARVD10, ARVD8, ARVD9, ARVDPPK, DSC2, DSG2, DSP, JUP, PKP
Wide spectrum of desmosomal mutations in Danish patients with arrhythmogenic right ventricular cardiomyopathy.
Christensen AH, Benn M, Bundgaard H, Tybjaerg-Hansen A, Haunso S, Svendsen JH.
J Med Genet 47(11):736-44. Epub 2010 Sep 23. 2010
7EVPL, JUP, LGALS7, PPL, SCEL, SPRR3
Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress.
Pyle AL, Li B, Maupin AB, Guzman RJ, Crimmins DL, Olson S, Atkinson JB, Young PP.
Cardiovasc Pathol 19(2):e13-20. Epub 2009 Feb 11. 2010
8DSC1, DSG1, JUP
Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
Choi HJ, Gross JC, Pokutta S, Weis WI.
J Biol Chem 284(46):31776-88. Epub 2009 Sep 16.PMID: 19759396 2009
9ARVD12, JUP
A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy.
Asimaki A, Syrris P, Wichter T, Matthias P, Saffitz JE, McKenna WJ.
Am J Hum Genet 81(5):964-73. Epub 2007 Sep 28. 2007
10JUP
Aberrant activation of gamma-catenin promotes genomic instability and oncogenic effects during tumor progression.
Pan H, Gao F, Papageorgis P, Abdolmaleky HM, Faller DV, Thiagalingam S.
Cancer Biol Ther 6(10):1638-43. Epub 2007 Aug 17. 2007
11JUP
Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.
Williamson L, Raess NA, Caldelari R, Zakher A, de Bruin A, Posthaus H, Bolli R, Hunziker T, Suter MM, Mčller EJ.
EMBO J 25(14):3298-309. 2006
12CTNNA1, CTNNA2, CTNNB1, JUP
Expression of Catenin family members CTNNA1, CTNNA2, CTNNB1 and JUP in the primate prefrontal cortex and hippocampus.
Smith A, Bourdeau I, Wang J, Bondy CA.
Brain Res Mol Brain Res 135(1-2):225-31. 2005
13AXIN1, AXIN2, CDH1, CTNNA1, JUP
Cadherin and catenin alterations in human cancer.
Hajra KM, Fearon ER.
Genes Chromosomes Cancer 34(3):255-68. Review. 2002
14TOP2A, GRB2, AOC3, AP2B1, KRT14, JUP, ITGA3
Targets of gene amplification and overexpression at 17q in gastric cancer.
Varis A, Wolf M, Monni O, Vakkari ML, Kokkola A, Moskaluk C, Frierson H Jr, Powell SM, Knuutila S, Kallioniemi A, El-Rifai W.
Cancer Res 62(9):2625-9. 2002
15ARVDPPK, JUP
Genotype-phenotype assessment in autosomal recessive arrhythmogenic right ventricular cardiomyopathy (Naxos disease) caused by a deletion in plakoglobin
Protonotarios N, Tsatsopoulou A, Anastasakis A, Sevdalis E, McKoy G, Stratos K, Gatzoulis K, Tentolouris K, Spiliopoulou C, Panagiotakos D, McKenna W, Toutouzas P.
J Am Coll Cardiol 38(5):1477-84. 2001
16JUP
Molecular cloning of a functional promoter of the human plakoglobin gene
Potter E, Braun S, Lehmann U, Brabant G.
Eur J Endocrinol 145(5):625-33. 2001
17JUP
Molecular organization of the desmoglein-plakoglobin complex.
Chitaev NA, et al.
J Cell Sci 111 : 1941-1949. 1998
18JUP, PKP1
The plakophilin 1 (PKP1) and plakoglobin (JUP) genes map to human chromosomes 1q and 17, respectively.
Cowley CM, Simrak D, Spurr NK, Arnemann J, Buxton RS.
Hum Genet 100(3-4):486-8. 1997
19JUP
The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers.
Aberle H, et al.
Proc Natl Acad Sci U S A 92 : 6384-6388. 1995
20APC, CTNNB1, CTNND1, JUP, KPNA3, ARVCF, CTNND2, KPNA2, PKP4, PKP1, PKP2, SPAG6
A repeating amino acid motif shared by proteins with diverse cellular roles.
Peifer M, et al.
Cell 76(5):789-91. No abstract available 1994
21DSC2, DSC3, DSG1, DSP, JUP
Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP).
Arnemann J, et al.
Genomics 10 : 640-645. 1991