| 1 | DSC3, DSP, JUP, SOX30
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| SOX30 is a key regulator of desmosomal gene suppressing tumor growth and metastasis in lung adenocarcinoma.
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| Hao X, Han F, Ma B, Zhang N, Chen H, Jiang X, Yin L, Liu W, Ao L, Cao J, Liu J.
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| J Exp Clin Cancer Res 37(1):111. doi: 10.1186/s13046-018-0778-3.
2018
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| 2 | DSC2, DSC3, JUP, LEF1
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| Plakoglobin as a regulator of desmocollin gene expression.
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| Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Műller EJ, Koch PJ.
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| J Invest Dermatol 133(12):2732-2740. doi: 10.1038/jid.2013.220. Epub 2013 May 7.
2013
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| 3 | ARVDPPK, JUP
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| Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy.
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| Li D, Liu Y, Maruyama M, Zhu W, Chen H, Zhang W, Reuter S, Lin SF, Haneline LS, Field LJ, Chen PS, Shou W.
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| Hum Mol Genet 20(23):4582-96. doi: 10.1093/hmg/ddr392. Epub 2011 Aug 31.
2011
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| 4 | DPAGT1, JUP
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| N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway.
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| Sengupta PK, Bouchie MP, Kukuruzinska MA.
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| J Biol Chem 285(41):31164-73. Epub 2010 Aug 6. 2010
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| 5 | ARVDPPK, JUP
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| Homozygous mutations in the 5' region of the JUP gene result in cutaneous disease but normal heart development in children.
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| Cabral RM, Liu L, Hogan C, Dopping-Hepenstal PJ, Winik BC, Asial RA, Dobson R, Mein CA, Baselaga PA, Mellerio JE, Nanda A, Boente Mdel C, Kelsell DP, McGrath JA, South AP.
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| J Invest Dermatol 130(6):1543-50. Epub 2010 Feb 4.
2010
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| 6 | ARVD10, ARVD8, ARVD9, ARVDPPK, DSC2, DSG2, DSP, JUP, PKP
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| Wide spectrum of desmosomal mutations in Danish patients with arrhythmogenic right ventricular cardiomyopathy.
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| Christensen AH, Benn M, Bundgaard H, Tybjaerg-Hansen A, Haunso S, Svendsen JH.
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| J Med Genet 47(11):736-44. Epub 2010 Sep 23.
2010
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| 7 | EVPL, JUP, LGALS7, PPL, SCEL, SPRR3
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| Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress.
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| Pyle AL, Li B, Maupin AB, Guzman RJ, Crimmins DL, Olson S, Atkinson JB, Young PP.
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| Cardiovasc Pathol 19(2):e13-20. Epub 2009 Feb 11. 2010
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| 8 | DSC1, DSG1, JUP
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| Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
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| Choi HJ, Gross JC, Pokutta S, Weis WI.
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| J Biol Chem 284(46):31776-88. Epub 2009 Sep 16.PMID: 19759396 2009
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| 9 | ARVD12, JUP
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| A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy.
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| Asimaki A, Syrris P, Wichter T, Matthias P, Saffitz JE, McKenna WJ.
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| Am J Hum Genet 81(5):964-73. Epub 2007 Sep 28. 2007
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| 10 | JUP
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| Aberrant activation of gamma-catenin promotes genomic instability and oncogenic effects during tumor progression.
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| Pan H, Gao F, Papageorgis P, Abdolmaleky HM, Faller DV, Thiagalingam S.
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| Cancer Biol Ther 6(10):1638-43. Epub 2007 Aug 17.
2007
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| 11 | JUP
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| Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.
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| Williamson L, Raess NA, Caldelari R, Zakher A, de Bruin A, Posthaus H, Bolli R, Hunziker T, Suter MM, MŸller EJ.
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| EMBO J 25(14):3298-309. 2006
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| 12 | CTNNA1, CTNNA2, CTNNB1, JUP
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| Expression of Catenin family members CTNNA1, CTNNA2, CTNNB1 and JUP in the primate prefrontal cortex and hippocampus.
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| Smith A, Bourdeau I, Wang J, Bondy CA.
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| Brain Res Mol Brain Res 135(1-2):225-31.
2005
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| 13 | AXIN1, AXIN2, CDH1, CTNNA1, JUP
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| Cadherin and catenin alterations in human cancer.
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| Hajra KM, Fearon ER.
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| Genes Chromosomes Cancer 34(3):255-68. Review. 2002
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| 14 | TOP2A, GRB2, AOC3, AP2B1, KRT14, JUP, ITGA3
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| Targets of gene amplification and overexpression at 17q in gastric cancer.
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| Varis A, Wolf M, Monni O, Vakkari ML, Kokkola A, Moskaluk C, Frierson H Jr, Powell SM, Knuutila S, Kallioniemi A, El-Rifai W.
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| Cancer Res 62(9):2625-9. 2002
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| 15 | ARVDPPK, JUP
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| Genotype-phenotype assessment in autosomal recessive arrhythmogenic right ventricular cardiomyopathy (Naxos disease) caused by a deletion in plakoglobin
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| Protonotarios N, Tsatsopoulou A, Anastasakis A, Sevdalis E, McKoy G, Stratos K, Gatzoulis K, Tentolouris K, Spiliopoulou C, Panagiotakos D, McKenna W, Toutouzas P.
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| J Am Coll Cardiol 38(5):1477-84. 2001
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| 16 | JUP
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| Molecular cloning of a functional promoter of the human plakoglobin gene
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| Potter E, Braun S, Lehmann U, Brabant G.
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| Eur J Endocrinol 145(5):625-33. 2001
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| 17 | JUP
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| Molecular organization of the desmoglein-plakoglobin complex.
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| Chitaev NA, et al.
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| J Cell Sci 111 : 1941-1949. 1998
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| 18 | JUP, PKP1
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| The plakophilin 1 (PKP1) and plakoglobin (JUP) genes map to human chromosomes 1q and 17, respectively.
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| Cowley CM, Simrak D, Spurr NK, Arnemann J, Buxton RS.
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| Hum Genet 100(3-4):486-8. 1997
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| 19 | JUP
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| The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers.
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| Aberle H, et al.
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| Proc Natl Acad Sci U S A 92 : 6384-6388. 1995
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| 20 | APC, CTNNB1, CTNND1, JUP, KPNA3, ARVCF, CTNND2, KPNA2, PKP4, PKP1, PKP2, SPAG6
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| A repeating amino acid motif shared by proteins with diverse cellular roles.
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| Peifer M, et al.
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| Cell 76(5):789-91. No abstract available 1994
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| 21 | DSC2, DSC3, DSG1, DSP, JUP
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| Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP).
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| Arnemann J, et al.
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| Genomics 10 : 640-645. 1991
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