1 | CARM1, JMJD6, MED12
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| JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex.
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| Gao WW, Xiao RQ, Zhang WJ, Hu YR, Peng BL, Li WJ, He YH, Shen HF, Ding JC, Huang QX, Ye TY, Li Y, Liu ZY, Ding R, Rosenfeld MG, Liu W.
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| Mol Cell 70(2):340-357.e8. doi: 10.1016/j.molcel.2018.03.006. Epub 2018 Apr 5.
2018
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2 | HOTAIR, JMJD6
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| JMJD6 induces HOTAIR, an oncogenic lincRNA, by physically interacting with its proximal promoter.
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| Biswas A, Shettar A, Mukherjee G, Kondaiah P, Desai KV.
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| Biochem J 475(1):355-371. doi: 10.1042/BCJ20170664.
2018
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3 | JMJD6
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| JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component.
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| Liu X, Si W, Liu X, He L, Ren J, Yang Z, Yang J, Li W, Liu S, Pei F, Yang X, Sun L.
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| Mol Cancer 16(1):175. doi: 10.1186/s12943-017-0744-2.
2017
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4 | G3BP1, JMJD6, PRMT1, PRMT5
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| Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1.
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| Tsai WC, Reineke LC, Jain A, Jung SY, Lloyd RE.
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| J Biol Chem 292(46):18886-18896. doi: 10.1074/jbc.M117.800706. Epub 2017 Sep 27.
2017
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5 | JMJD6
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| Bifunctional Enzyme JMJD6 Contributes to Multiple Disease Pathogenesis: New Twist on the Old Story.
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| Vangimalla SS, Ganesan M, Kharbanda KK, Osna NA.
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| Biomolecules 7(2). pii: E41. doi: 10.3390/biom7020041. Review.
2017
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6 | JMJD6
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| Jmjd6, a JmjC Dioxygenase with Many Interaction Partners and Pleiotropic Functions.
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| Kwok J, O'Shea M, Hume DA, Lengeling A.
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| Front Genet 8:32. doi: 10.3389/fgene.2017.00032. eCollection 2017. Review.
2017
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7 | JMJD6, U2AF2
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| JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner.
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| Yi J, Shen HF, Qiu JS, Huang MF, Zhang WJ, Ding JC, Zhu XY, Zhou Y, Fu XD, Liu W.
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| Nucleic Acids Res 45(6):3503-3518. doi: 10.1093/nar/gkw1144.
2017
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8 | FLT1, JMJD6
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| Jumonji Domain Containing Protein 6 Is Decreased in Human Preeclamptic Placentas and Regulates sFLT-1 Splice Variant Production.
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| Palmer KR, Tong S, Tuohey L, Cannon P, Ye L, Hannan NJ, Brownfoot FC, Illanes SE, Kaitu'u-Lino TJ.
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| Biol Reprod 94(3):59. doi: 10.1095/biolreprod.115.134460. Epub 2016 Jan 27.
2016
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9 | CEBPA, CEBPB, CEBPD, JMJD6, PPARG
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| Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.
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| Hu YJ, Belaghzal H, Hsiao WY, Qi J, Bradner JE, Guertin DA, Sif S, Imbalzano AN.
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| Nucleic Acids Res 43(16):7790-804. doi: 10.1093/nar/gkv645. Epub 2015 Jun 27.
2015
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10 | JMJD6
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| Jumonji Domain Containing Protein 6: A Novel Oxygen Sensor in the Human Placenta.
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| Alahari S, Post M, Caniggia I.
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| Endocrinology 156(8):3012-25. doi: 10.1210/en.2015-1262. Epub 2015 Jun 2.
2015
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11 | JMJD6, MDM4, TP53
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| JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation.
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| Wang F, He L, Huangyang P, Liang J, Si W, Yan R, Han X, Liu S, Gui B, Li W, Miao D, Jing C, Liu Z, Pei F, Sun L, Shang Y.
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| PLoS Biol 12(3):e1001819. doi: 10.1371/journal.pbio.1001819. eCollection 2014 Mar.
2014
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12 | BRD4, CDK9, JMJD6
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| Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release.
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| Liu W, Ma Q, Wong K, Li W, Ohgi K, Zhang J, Aggarwal A, Rosenfeld MG.
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| Cell 155(7):1581-1595. doi: 10.1016/j.cell.2013.10.056.
2013
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13 | JMJD6
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| Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
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| Unoki M, Masuda A, Dohmae N, Arita K, Yoshimatsu M, Iwai Y, Fukui Y, Ueda K, Hamamoto R, Shirakawa M, Sasaki H, Nakamura Y.
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| J Biol Chem 288(9):6053-62. doi: 10.1074/jbc.M112.433284. Epub 2013 Jan 9.
2013
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14 | HIF1AN, JMJD6, KDM8
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| Crystal structure and functional analysis of JMJD5 indicate an alternate specificity and function.
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| Del Rizzo PA, Krishnan S, Trievel RC.
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| Mol Cell Biol 32(19):4044-52. doi: 10.1128/MCB.00513-12. Epub 2012 Jul 30.
2012
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15 | FLT1, JMJD6, U2AF2
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| Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1.
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| Boeckel JN, Guarani V, Koyanagi M, Roexe T, Lengeling A, Schermuly RT, Gellert P, Braun T, Zeiher A, Dimmeler S.
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| Proc Natl Acad Sci U S A 108(8):3276-81. Epub 2011 Feb 7.
2011
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16 | JMJD6
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| Interaction of JMJD6 with single-stranded RNA.
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| Hong X, Zang J, White J, Wang C, Pan CH, Zhao R, Murphy RC, Dai S, Henson P, Kappler JW, Hagman J, Zhang G.
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| Proc Natl Acad Sci U S A 107(33):14568-72. Epub 2010 Aug 2.PMID: 20679243 2010
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17 | JMJD6, U2AF2
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| Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.
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| Webby CJ, Wolf A, Gromak N, Dreger M, Kramer H, Kessler B, Nielsen ML, Schmitz C, Butler DS, Yates JR 3rd, Delahunty CM, Hahn P, Lengeling A, Mann M, Proudfoot NJ, Schofield CJ, Böttger A.
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| Science 325(5936):90-3.
2009
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18 | JMJD6
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| Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins.
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| Hahn P, Böse J, Edler S, Lengeling A.
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| BMC Genomics 9:293.
2008
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19 | JMJD6
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| Characterization of the biochemical and biophysical properties of the phosphatidylserine receptor (PS-R) gene product.
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| Tibrewal N, Liu T, Li H, Birge RB.
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| Mol Cell Biochem 304(1-2):119-25. Epub 2007 May 30. 2007
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20 | JMJD6
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| JMJD6 is a histone arginine demethylase.
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| Chang B, Chen Y, Zhao Y, Bruick RK.
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| Science 318(5849):444-7. 2007
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21 | JMJD6
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| JmjC-domain-containing proteins and histone demethylation.
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| Klose RJ, Kallin EM, Zhang Y.
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| Nat Rev Genet 7(9):715-27. 2006
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22 | ELMO1, ELMO2, ELMO3, JMJD6
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| Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.
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| Wang X, Wu YC, Fadok VA, Lee MC, Gengyo-Ando K, Cheng LC, Ledwich D, Hsu PK, Chen JY, Chou BK, Henson P, Mitani S, Xue D.
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| Science 302(5650):1563-6.
2003
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23 | JMJD6
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| A receptor for phosphatidylserine-specific clearance of apoptotic cells.
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| Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RA, Henson PM.
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| Nature 405(6782):85-90. 2000
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