1 | JAM3
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| JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer.
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| Zhou D, Tang W, Zhang Y, An HX.
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| Cancer Manag Res. Mar 27;11:2457-2470. doi: 10.2147/CMAR.S189937. eCollection 2019 2019
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2 | JAM3
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| Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration.
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| Kostelnik KB, Barker A, Schultz C, Mitchell TP, Rajeeve V, White IJ, Aurrand-Lions M, Nourshargh S, Cutillas P, Nightingale TD.
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| PLoS Biol. Dec 2;17(12):e3000554. doi: 10.1371/journal.pbio.3000554. eCollection 2019 Dec 2019
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3 | JAM3
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| Jam3 promotes migration and suppresses apoptosis of renal carcinoma cell lines.
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| Li X, Yin A, Zhang W, Zhao F, Lv J, Lv J, Sun J.
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| Int J Mol Med. Nov;42(5):2923-2929. doi: 10.3892/ijmm.2018.3854. Epub 2018 Sep 4 2018
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4 | JAM3
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| Targeting junctional adhesion molecule-C ameliorates sepsis-induced acute lung injury by decreasing CXCR4+ aged neutrophils.
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| Hirano Y, Ode Y, Ochani M, Wang P, Aziz M.
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| J Leukoc Biol. Dec;104(6):1159-1171. doi: 10.1002/JLB.3A0218-050R. Epub 2018 Aug 8 2018
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5 | GORASP2, JAM3
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| Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis.
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| Cartier-Michaud A, Bailly AL, Betzi S, Shi X, Lissitzky JC, Zarubica A, Sergé A, Roche P, Lugari A, Hamon V, Bardin F, Derviaux C, Lembo F, Audebert S, Marchetto S, Durand B, Borg JP, Shi N, Morelli X, Aurrand-Lions M.
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| PLoS Genet. Jun 15;13(6):e1006803. doi: 10.1371/journal.pgen.1006803. eCollection 2017 Jun 2017
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6 | JAM3, KDR
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| JAM-C maintains VEGR2 expression to promote retinal pigment epithelium cell survival under oxidative stress.
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| Jia X, Zhao C, Chen Q, Du Y, Huang L, Ye Z, Ren X, Wang S, Lee C, Tang Z, Li X, Ju R.
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| Thromb Haemost. Apr 3;117(4):750-757. doi: 10.1160/TH16-11-0885. Epub 2017 Feb 16 2017
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7 | JAM2, JAM3
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| Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.
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| Arcangeli ML, Bardin F, Frontera V, Bidaut G, Obrados E, Adams RH, Chabannon C, Aurrand-Lions M.
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| Stem Cells Apr;32(4):1043-54. doi: 10.1002/stem.1624 2014
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8 | JAM3
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| Homing of human B cells to lymphoid organs and B-cell lymphoma engraftment are controlled by cell adhesion molecule JAM-C.
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| Doñate C, Ody C, McKee T, Ruault-Jungblut S, Fischer N, Ropraz P, Imhof BA, Matthes T.
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| Cancer Res 73(2):640-51. doi: 10.1158/0008-5472.CAN-12-1756. Epub 2012 Dec 5.
2013
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9 | BCPMG2, JAM3
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| Delineation of the clinical, molecular and cellular aspects of novel JAM3 mutations underlying the autosomal recessive hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts.
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| Akawi NA, Canpolat FE, White SM, Quilis-Esquerra J, Morales Sanchez M, Gamundi MJ, Mochida GH, Walsh CA, Ali BR, Al-Gazali L.
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| Hum Mutat 34(3):498-505. doi: 10.1002/humu.22263.
2013
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10 | JAM2, JAM3
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| Junctional adhesion molecules 2 and 3 may potentially be involved in progression of gastric adenocarcinoma tumors.
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| Hajjari M, Behmanesh M, Sadeghizadeh M, Zeinoddini M.
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| Med Oncol. Mar;30(1):380. doi: 10.1007/s12032-012-0380-z. Epub 2013 Jan 1 2013
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11 | JAM2, JAM3
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| The Junctional Adhesion Molecule-B regulates JAM-C-dependent melanoma cell metastasis.
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| Arcangeli ML, Frontera V, Bardin F, Thomassin J, Chetaille B, Adams S, Adams RH, Aurrand-Lions M.
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| FEBS Lett 586(22):4046-51. doi: 10.1016/j.febslet.2012.10.005. Epub 2012 Oct 12.
2012
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12 | JAM3
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| JAM-C is an apical surface marker for neural stem cells.
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| Stelzer S, Worlitzer MM, Bahnassawy L, Hemmer K, Rugani K, Werthschulte I, Schön AL, Brinkmann BF, Bunk EC, Palm T, Ebnet K, Schwamborn JC.
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| Stem Cells Dev 21(5):757-66. doi: 10.1089/scd.2011.0274. Epub 2012 Jan 17.
2012
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13 | JAM2, JAM3
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| JAM-B regulates maintenance of hematopoietic stem cells in the bone marrow.
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| Arcangeli ML, Frontera V, Bardin F, Obrados E, Adams S, Chabannon C, Schiff C, Mancini SJ, Adams RH, Aurrand-Lions M.
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| Blood 118(17):4609-19. doi: 10.1182/blood-2010-12-323972. Epub 2011 Aug 25.
2011
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14 | JAM2, JAM3
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| Jamb and jamc are essential for vertebrate myocyte fusion.
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| Powell GT, Wright GJ.
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| PLoS Biol 9(12):e1001216. doi: 10.1371/journal.pbio.1001216. Epub 2011 Dec 13.
2011
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15 | JAM3
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| The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo.
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| Woodfin A, Voisin MB, Beyrau M, Colom B, Caille D, Diapouli FM, Nash GB, Chavakis T, Albelda SM, Rainger GE, Meda P, Imhof BA, Nourshargh S.
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| Nat Immunol 12(8):761-9. doi: 10.1038/ni.2062.
2011
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16 | BCPMG2, JAM3
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| A homozygous mutation in the tight-junction protein JAM3 causes hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts.
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| Mochida GH, Ganesh VS, Felie JM, Gleason D, Hill RS, Clapham KR, Rakiec D, Tan WH, Akawi N, Al-Saffar M, Partlow JN, Tinschert S, Barkovich AJ, Ali B, Al-Gazali L, Walsh CA.
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| Am J Hum Genet 87(6):882-9. Epub 2010 Nov 25.PMID: 21109224 2010
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17 | JAM2, JAM3
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| Cooperative expression of junctional adhesion molecule-C and -B supports growth and invasion of glioma.
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| Tenan M, Aurrand-Lions M, Widmer V, Alimenti A, Burkhardt K, Lazeyras F, Belkouch MC, Hammel P, Walker PR, Duchosal MA, Imhof BA, Dietrich PY.
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| Glia 58(5):524-37. doi: 10.1002/glia.20941.
2010
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18 | DEL11QD, HLHS2, JAM3
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| Deletion of JAM-C, a candidate gene for heart defects in Jacobsen syndrome, results in a normal cardiac phenotype in mice.
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| Ye M, Hamzeh R, Geddis A, Varki N, Perryman MB, Grossfeld P.
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| Am J Med Genet A 149A(7):1438-43.
2009
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19 | JAM3
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| Expression, localization, and function of junctional adhesion molecule-C (JAM-C) in human retinal pigment epithelium.
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| Economopoulou M, Hammer J, Wang F, Fariss R, Maminishkis A, Miller SS.
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| Invest Ophthalmol Vis Sci. 50(3):1454-63. 2009
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20 | JAM1, JAM2, JAM3
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| Expression of junctional adhesion molecules on the human lymphatic endothelium.
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| Ueki T, Iwasawa K, Ishikawa H, Sawa Y.
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| Microvasc Res 75(2):269-78. Epub 2007 Aug 3.
2008
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21 | JAM3
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| Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves.
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| Scheiermann C, Meda P, Aurrand-Lions M, Madani R, Yiangou Y, Coffey P, Salt TE, Ducrest-Gay D, Caille D, Howell O, Reynolds R, Lobrinus A, Adams RH, Yu AS, Anand P, Imhof BA, Nourshargh S.
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| Science 318(5855):1472-5. 2007
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22 | JAM3
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| JAM-C regulates unidirectional monocyte transendothelial migration in inflammation.
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| Bradfield PF, Scheiermann C, Nourshargh S, Ody C, Luscinskas FW, Rainger GE, Nash GB, Miljkovic-Licina M, Aurrand-Lions M, Imhof BA.
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| Blood 110(7):2545-55. Epub 2007 Jul 11. 2007
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23 | JAM3
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| Junctional adhesion molecule C (JAM-C) distinguishes CD27+ germinal center B lymphocytes from non-germinal center cells and constitutes a new diagnostic tool for B-cell malignancies.
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| Ody C, Jungblut-Ruault S, Cossali D, Barnet M, Aurrand-Lions M, Imhof BA, Matthes T.
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| Leukemia 21(6):1285-93. Epub 2007 Apr 12. 2007
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24 | F11R, JAM2, JAM3
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| Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium.
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| Daniele LL, Adams RH, Durante DE, Pugh EN Jr, Philp NJ.
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| J Comp Neurol 505(2):166-76.
2007
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25 | JAM3, TJP1
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| Junctional Adhesion Molecules (JAMs) are differentially expressed in fibroblasts and co-localize with ZO-1 to adherens-like junctions.
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| Morris AP, Tawil A, Berkova Z, Wible L, Smith CW, Cunningham SA.
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| Cell Commun Adhes 13(4):233-47. 2006
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26 | JAM3
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| Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation.
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| Aurrand-Lions M, Lamagna C, Dangerfield JP, Wang S, Herrera P, Nourshargh S, Imhof BA.
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| J Immunol 174(10):6406-15. 2005
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27 | JAM2, JAM3
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| Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation.
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| Ludwig RJ, Zollner TM, Santoso S, Hardt K, Gille J, Baatz H, Johann PS, Pfeffer J, Radeke HH, Schön MP, Kaufmann R, Boehncke WH, Podda M.
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| J Invest Dermatol 125(5):969-76.
2005
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28 | JAM3
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| JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration.
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| Zen K, Babbin BA, Liu Y, Whelan JB, Nusrat A, Parkos CA.
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| Mol Biol Cell 15(8):3926-37. Epub 2004 Jun 11. 2004
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29 | JAM3
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| Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C.
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| Gliki G, Ebnet K, Aurrand-Lions M, Imhof BA, Adams RH.
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| Nature. 431(7006):320-4. 2004
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30 | JAM3
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| The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity.
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| Ebnet K, Aurrand-Lions M, Kuhn A, Kiefer F, Butz S, Zander K, Meyer zu Brickwedde MK, Suzuki A, Imhof BA, Vestweber D.
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| J Cell Sci. 116(Pt 19):3879-91. 2003
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31 | JAM1, JAM2, JAM3
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| The JAM family of junctional adhesion molecules.
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| Bazzoni G.
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| Curr Opin Cell Biol 15(5):525-30. Review.
2003
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32 | JAM2, JAM3
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| Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3.
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| Liang TW, Chiu HH, Gurney A, Sidle A, Tumas DB, Schow P, Foster J, Klassen T, Dennis K, DeMarco RA, Pham T, Frantz G, Fong S.
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| J Immunol 168(4):1618-26. 2002
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33 | DEL11QD, HLHS2, JAM3
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| Narrowing the critical region within 11q24-qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis.
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| Phillips HM, Renforth GL, Spalluto C, Hearn T, Curtis AR, Craven L, Havarani B, Clement-Jones M, English C, Stumper O, Salmon T, Hutchinson S, Jackson MS, Wilson DI.
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| Genomics 79(4):475-8. 2002
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34 | JAM3
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| The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1.
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| Santoso S, Sachs UJ, Kroll H, Linder M, Ruf A, Preissner KT, Chavakis T.
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| J Exp Med. 196(5):679-91. 2002
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35 | JAM3
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| Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor.
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| Arrate MP, Rodriguez JM, Tran TM, Brock TA, Cunningham SA.
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| J Biol Chem 276(49):45826-32. 2001
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