Citations for
1JAK1
JAK1 as a prognostic marker and its correlation with immune infiltrates in breast cancer.
Chen B, Lai J, Dai D, Chen R, Li X, Liao N.
Aging (Albany NY) Dec 2;11(23):11124-11135. doi: 10.18632/aging.102514. Epub 2019 Dec 2 2019
2JAK1, JAK2
Loss of JAK1 Drives Innate Immune Deficiency.
Witalisz-Siepracka A, Klein K, Prinz D, Leidenfrost N, Schabbauer G, Dohnal A, Sexl V.
Front Immunol. Jan 8;9:3108. doi: 10.3389/fimmu.2018.03108. eCollection 2018 2019
3JAK1, JAK2
Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling.
Raivola J, Haikarainen T, Silvennoinen O.
Cancers (Basel) Dec 27;12(1):78. doi: 10.3390/cancers12010078 2019
4CLDN10, JAK1
CLDN10 promotes a malignant phenotype of osteosarcoma cells via JAK1/Stat1 signaling.
Zhang X, Wang X, Wang A, Li Q, Zhou M, Li T.
J Cell Commun Signal. Sep;13(3):395-405. doi: 10.1007/s12079-019-00509-7. Epub 2019 Feb 22 2019
5JAK1
Genome-Wide CRISPR Screening Identifies JAK1 Deficiency as a Mechanism of T-Cell Resistance.
Han P, Dai Q, Fan L, Lin H, Zhang X, Li F, Yang X.
Front Immunol. Feb 19;10:251. doi: 10.3389/fimmu.2019.00251. eCollection 2019 2019
6JAK1
Janus kinase JAK1 maintains the ovarian reserve of primordial follicles in the mouse ovary.
Sutherland JM, Frost ER, Ford EA, Peters AE, Reed NL, Seldon AN, Mihalas BP, Russel DL, Dunning KR, McLaughlin EA.
Mol Hum Reprod. Nov 1;24(11):533-542. doi: 10.1093/molehr/gay041 2018
7JAK1, JAK2, SOCS1
Expression and Purification of JAK1 and SOCS1 for Structural and Biochemical Studies.
Liau NPD, Babon JJ.
Methods Mol Biol. 1725:267-280. doi: 10.1007/978-1-4939-7568-6_21 2018
8JAK1
Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.
Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, Levine RL.
Cell Stem Cell. Oct 5;21(4):489-501.e7. doi: 10.1016/j.stem.2017.08.011. Epub 2017 Sep 28 2017
9JAK1
Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma.
Zhu F, Hwang B, Miyamoto S, Rui L.
Mol Cancer Res. Mar;15(3):348-357. doi: 10.1158/1541-7786.MCR-16-0344. Epub 2016 Dec 28 2017
10CISH, IL15, JAK1
CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, Andoniou CE, Degli-Esposti MA, Sharp PP, Sanvitale CE, Infusini G, Liau NP, Linossi EM, Burns CJ, Carotta S, Gray DH, Seillet C, Hutchinson DS, Belz GT, Webb AI, Alexander WS, Li SS, Bullock AN, Babon JJ, Smyth MJ, Nicholson SE, Huntington ND.
Nat Immunol. Jul;17(7):816-24. doi: 10.1038/ni.3470. Epub 2016 May 23 2016
11JAK1
The Structural Basis for Class II Cytokine Receptor Recognition by JAK1.
Ferrao R, Wallweber HJ, Ho H, Tam C, Franke Y, Quinn J, Lupardus PJ.
Structure Jun 7;24(6):897-905. doi: 10.1016/j.str.2016.03.023. Epub 2016 Apr 28 2016
12CD274, IFNG, JAK1, JAK2
Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression.
Bellucci R, Martin A, Bommarito D, Wang K, Hansen SH, Freeman GJ, Ritz J.
Oncoimmunology Mar 2;4(6):e1008824. doi: 10.1080/2162402X.2015.1008824. eCollection 2015 Jun. 2015
13JAK1
JAK1 truncating mutations in gynecologic cancer define new role of cancer-associated protein tyrosine kinase aberrations.
Ren Y, Zhang Y, Liu RZ, Fenstermacher DA, Wright KL, Teer JK, Wu J.
Sci Rep. Oct 24;3:3042. doi: 10.1038/srep03042 2013
14JAK1, PTPN2
PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.
Kleppe M, Soulier J, Asnafi V, Mentens N, Hornakova T, Knoops L, Constantinescu S, Sigaux F, Meijerink JP, Vandenberghe P, Tartaglia M, Foa R, Macintyre E, Haferlach T, Cools J.
Blood 117(26):7090-8. Epub 2011 May 6. 2011
15JAK1, TJP2
The tight junction protein ZO-2 and Janus kinase 1 mediate intercellular communications in vascular smooth muscle cells.
Tkachuk N, Tkachuk S, Patecki M, Kusch A, Korenbaum E, Haller H, Dumler I.
Biochem Biophys Res Commun 410(3):531-6. Epub 2011 Jun 7. 2011
16JAK1, ROCK1
ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma.
Sanz-Moreno V, Gaggioli C, Yeo M, Albrengues J, Wallberg F, Viros A, Hooper S, Mitter R, Féral CC, Cook M, Larkin J, Marais R, Meneguzzi G, Sahai E, Marshall CJ.
Cancer Cell 20(2):229-45. 2011
17JAK1, JAK2, JAK3
JAK mutations in high-risk childhood acute lymphoblastic leukemia.
Mullighan CG, Zhang J, Harvey RC, Collins-Underwood JR, Schulman BA, Phillips LA, Tasian SK, Loh ML, Su X, Liu W, Devidas M, Atlas SR, Chen IM, Clifford RJ, Gerhard DS, Carroll WL, Reaman GH, Smith M, Downing JR, Hunger SP, Willman CL.
Proc Natl Acad Sci U S A 106(23):9414-8. Epub 2009 May 22. 2009
18JAK1
Mutational analysis of JAK1 gene in human hepatocellular carcinoma.
Xie HJ, Bae HJ, Noh JH, Eun JW, Kim JK, Jung KH, Ryu JC, Ahn YM, Kim SY, Lee SH, Yoo NJ, Lee JY, Park WS, Nam SW.
Neoplasma 56(2):136-40. 2009
19JAK1, PIAS1, SOCS1, SOCS3, STAT1, STAT3
SOCS1, SOCS3, and PIAS1 promote myogenic differentiation by inhibiting the leukemia inhibitory factor-induced JAK1/STAT1/STAT3 pathway.
Diao Y, Wang X, Wu Z.
Mol Cell Biol 29(18):5084-93. Epub 2009 Jul 20. 2009
20JAK1, JAK3
Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers.
Jeong EG, Kim MS, Nam HK, Min CK, Lee S, Chung YJ, Yoo NJ, Lee SH.
Clin Cancer Res 14(12):3716-21. 2008
21JAK1
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.
Flex E, Petrangeli V, Stella L, Chiaretti S, Hornakova T, Knoops L, Ariola C, Fodale V, Clappier E, Paoloni F, Martinelli S, Fragale A, Sanchez M, Tavolaro S, Messina M, Cazzaniga G, Camera A, Pizzolo G, Tornesello A, Vignetti M, Battistini A, Cavé H, Gelb BD, Renauld JC, Biondi A, Constantinescu SN, Foŕ R, Tartaglia M.
J Exp Med 205(4):751-8. Epub 2008 Mar 24. 2008
22JAK1
Identification of somatic JAK1 mutations in patients with acute myeloid leukemia.
Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner TL, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, Heath SE, Nagarajan R, Mardis ER, Wilson RK, Ley TJ, Tomasson MH.
Blood 111(9):4809-12. Epub 2007 Dec 26. 2008
23JAK1
JAK1 N-terminus binds to conserved Box 1 and Box 2 motifs of cytokine receptor common beta subunit but signal activation requires JAK1 C-terminus.
Huang HM, Lee YL, Chang TW.
J Cell Biochem 99(4):1078-84. 2006
24JAK1, JAK2
Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.
Huang HM, Lin YL, Chen CH, Chang TW.
J Cell Biochem 96(2):361-75. 2005
25JAKMIP1, JAK1, TYK2
Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules.
Steindler C, Li Z, Algarte M, Alcover A, Libri V, Ragimbeau J, Pellegrini S.
J Biol Chem 279(41):43168-77. Epub 2004 Jul 23. 2004
26JAK1
YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling.
O'Brien KB, Argetsinger LS, Diakonova M, Carter-Su C.
J Biol Chem 278(14):11970-8. Epub 2003 Jan 27. 2003
27JAK1, JAK3
Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation.
Liu KD, Gaffen SL, Goldsmith MA, Greene WC.
Curr Biol 7(11):817-26. 1997
28JAK1
Confirmed assignment of a novel human tyrosine kinase gene (JAK1A) to 1p32.3-p31.3 by nonisotopic in situ hybridization.
Modi WS, et al.
Cytogenet Cell Genet 69 : 232-234. 1995
29TYK2, JAK1
Characterization of a class 3 tyrosine kinase.
Howard OMZ, et al.
Oncogene 7 : 895-900. 1992
30JAK1, JAK2
Two members of the JAK family of protein tyrosine kinases map to chromosomes 1p31.3 and 9p24.
Pritchard MA, et al.
Mamm Genome 3 : 36-38. 1992
31JAK1, JAK2
Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.
Wilks AF, et al.
Mol Cell Biol 11 : 2057-2065. 1991