| 1 | JAK1
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| JAK1 as a prognostic marker and its correlation with immune infiltrates in breast cancer.
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| Chen B, Lai J, Dai D, Chen R, Li X, Liao N.
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| Aging (Albany NY) Dec 2;11(23):11124-11135. doi: 10.18632/aging.102514. Epub 2019 Dec 2 2019
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| 2 | JAK1, JAK2
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| Loss of JAK1 Drives Innate Immune Deficiency.
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| Witalisz-Siepracka A, Klein K, Prinz D, Leidenfrost N, Schabbauer G, Dohnal A, Sexl V.
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| Front Immunol. Jan 8;9:3108. doi: 10.3389/fimmu.2018.03108. eCollection 2018 2019
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| 3 | JAK1, JAK2
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| Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling.
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| Raivola J, Haikarainen T, Silvennoinen O.
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| Cancers (Basel) Dec 27;12(1):78. doi: 10.3390/cancers12010078 2019
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| 4 | CLDN10, JAK1
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| CLDN10 promotes a malignant phenotype of osteosarcoma cells via JAK1/Stat1 signaling.
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| Zhang X, Wang X, Wang A, Li Q, Zhou M, Li T.
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| J Cell Commun Signal. Sep;13(3):395-405. doi: 10.1007/s12079-019-00509-7. Epub 2019 Feb 22 2019
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| 5 | JAK1
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| Genome-Wide CRISPR Screening Identifies JAK1 Deficiency as a Mechanism of T-Cell Resistance.
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| Han P, Dai Q, Fan L, Lin H, Zhang X, Li F, Yang X.
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| Front Immunol. Feb 19;10:251. doi: 10.3389/fimmu.2019.00251. eCollection 2019 2019
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| 6 | JAK1
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| Janus kinase JAK1 maintains the ovarian reserve of primordial follicles in the mouse ovary.
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| Sutherland JM, Frost ER, Ford EA, Peters AE, Reed NL, Seldon AN, Mihalas BP, Russel DL, Dunning KR, McLaughlin EA.
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| Mol Hum Reprod. Nov 1;24(11):533-542. doi: 10.1093/molehr/gay041 2018
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| 7 | JAK1, JAK2, SOCS1
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| Expression and Purification of JAK1 and SOCS1 for Structural and Biochemical Studies.
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| Liau NPD, Babon JJ.
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| Methods Mol Biol. 1725:267-280. doi: 10.1007/978-1-4939-7568-6_21 2018
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| 8 | JAK1
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| Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.
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| Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, Levine RL.
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| Cell Stem Cell. Oct 5;21(4):489-501.e7. doi: 10.1016/j.stem.2017.08.011. Epub 2017 Sep 28 2017
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| 9 | JAK1
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| Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma.
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| Zhu F, Hwang B, Miyamoto S, Rui L.
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| Mol Cancer Res. Mar;15(3):348-357. doi: 10.1158/1541-7786.MCR-16-0344. Epub 2016 Dec 28 2017
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| 10 | CISH, IL15, JAK1
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| CIS is a potent checkpoint in NK cell-mediated tumor immunity.
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| Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, Andoniou CE, Degli-Esposti MA, Sharp PP, Sanvitale CE, Infusini G, Liau NP, Linossi EM, Burns CJ, Carotta S, Gray DH, Seillet C, Hutchinson DS, Belz GT, Webb AI, Alexander WS, Li SS, Bullock AN, Babon JJ, Smyth MJ, Nicholson SE, Huntington ND.
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| Nat Immunol. Jul;17(7):816-24. doi: 10.1038/ni.3470. Epub 2016 May 23 2016
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| 11 | JAK1
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| The Structural Basis for Class II Cytokine Receptor Recognition by JAK1.
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| Ferrao R, Wallweber HJ, Ho H, Tam C, Franke Y, Quinn J, Lupardus PJ.
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| Structure Jun 7;24(6):897-905. doi: 10.1016/j.str.2016.03.023. Epub 2016 Apr 28 2016
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| 12 | CD274, IFNG, JAK1, JAK2
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| Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression.
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| Bellucci R, Martin A, Bommarito D, Wang K, Hansen SH, Freeman GJ, Ritz J.
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| Oncoimmunology Mar 2;4(6):e1008824. doi: 10.1080/2162402X.2015.1008824. eCollection 2015 Jun. 2015
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| 13 | JAK1
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| JAK1 truncating mutations in gynecologic cancer define new role of cancer-associated protein tyrosine kinase aberrations.
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| Ren Y, Zhang Y, Liu RZ, Fenstermacher DA, Wright KL, Teer JK, Wu J.
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| Sci Rep. Oct 24;3:3042. doi: 10.1038/srep03042 2013
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| 14 | JAK1, PTPN2
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| PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.
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| Kleppe M, Soulier J, Asnafi V, Mentens N, Hornakova T, Knoops L, Constantinescu S, Sigaux F, Meijerink JP, Vandenberghe P, Tartaglia M, Foa R, Macintyre E, Haferlach T, Cools J.
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| Blood 117(26):7090-8. Epub 2011 May 6.
2011
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| 15 | JAK1, TJP2
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| The tight junction protein ZO-2 and Janus kinase 1 mediate intercellular communications in vascular smooth muscle cells.
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| Tkachuk N, Tkachuk S, Patecki M, Kusch A, Korenbaum E, Haller H, Dumler I.
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| Biochem Biophys Res Commun 410(3):531-6. Epub 2011 Jun 7.
2011
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| 16 | JAK1, ROCK1
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| ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma.
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| Sanz-Moreno V, Gaggioli C, Yeo M, Albrengues J, Wallberg F, Viros A, Hooper S, Mitter R, Féral CC, Cook M, Larkin J, Marais R, Meneguzzi G, Sahai E, Marshall CJ.
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| Cancer Cell 20(2):229-45.
2011
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| 17 | JAK1, JAK2, JAK3
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| JAK mutations in high-risk childhood acute lymphoblastic leukemia.
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| Mullighan CG, Zhang J, Harvey RC, Collins-Underwood JR, Schulman BA, Phillips LA, Tasian SK, Loh ML, Su X, Liu W, Devidas M, Atlas SR, Chen IM, Clifford RJ, Gerhard DS, Carroll WL, Reaman GH, Smith M, Downing JR, Hunger SP, Willman CL.
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| Proc Natl Acad Sci U S A 106(23):9414-8. Epub 2009 May 22.
2009
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| 18 | JAK1
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| Mutational analysis of JAK1 gene in human hepatocellular carcinoma.
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| Xie HJ, Bae HJ, Noh JH, Eun JW, Kim JK, Jung KH, Ryu JC, Ahn YM, Kim SY, Lee SH, Yoo NJ, Lee JY, Park WS, Nam SW.
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| Neoplasma 56(2):136-40.
2009
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| 19 | JAK1, PIAS1, SOCS1, SOCS3, STAT1, STAT3
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| SOCS1, SOCS3, and PIAS1 promote myogenic differentiation by inhibiting the leukemia inhibitory factor-induced JAK1/STAT1/STAT3 pathway.
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| Diao Y, Wang X, Wu Z.
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| Mol Cell Biol 29(18):5084-93. Epub 2009 Jul 20.
2009
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| 20 | JAK1, JAK3
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| Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers.
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| Jeong EG, Kim MS, Nam HK, Min CK, Lee S, Chung YJ, Yoo NJ, Lee SH.
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| Clin Cancer Res 14(12):3716-21.
2008
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| 21 | JAK1
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| Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.
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| Flex E, Petrangeli V, Stella L, Chiaretti S, Hornakova T, Knoops L, Ariola C, Fodale V, Clappier E, Paoloni F, Martinelli S, Fragale A, Sanchez M, Tavolaro S, Messina M, Cazzaniga G, Camera A, Pizzolo G, Tornesello A, Vignetti M, Battistini A, Cavé H, Gelb BD, Renauld JC, Biondi A, Constantinescu SN, Foŕ R, Tartaglia M.
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| J Exp Med 205(4):751-8. Epub 2008 Mar 24.
2008
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| 22 | JAK1
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| Identification of somatic JAK1 mutations in patients with acute myeloid leukemia.
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| Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner TL, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, Heath SE, Nagarajan R, Mardis ER, Wilson RK, Ley TJ, Tomasson MH.
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| Blood 111(9):4809-12. Epub 2007 Dec 26.
2008
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| 23 | JAK1
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| JAK1 N-terminus binds to conserved Box 1 and Box 2 motifs of cytokine receptor common beta subunit but signal activation requires JAK1 C-terminus.
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| Huang HM, Lee YL, Chang TW.
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| J Cell Biochem 99(4):1078-84. 2006
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| 24 | JAK1, JAK2
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| Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.
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| Huang HM, Lin YL, Chen CH, Chang TW.
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| J Cell Biochem 96(2):361-75. 2005
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| 25 | JAKMIP1, JAK1, TYK2
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| Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules.
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| Steindler C, Li Z, Algarte M, Alcover A, Libri V, Ragimbeau J, Pellegrini S.
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| J Biol Chem 279(41):43168-77. Epub 2004 Jul 23. 2004
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| 26 | JAK1
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| YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling.
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| O'Brien KB, Argetsinger LS, Diakonova M, Carter-Su C.
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| J Biol Chem 278(14):11970-8. Epub 2003 Jan 27. 2003
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| 27 | JAK1, JAK3
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| Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation.
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| Liu KD, Gaffen SL, Goldsmith MA, Greene WC.
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| Curr Biol 7(11):817-26. 1997
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| 28 | JAK1
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| Confirmed assignment of a novel human tyrosine kinase gene (JAK1A) to 1p32.3-p31.3 by nonisotopic in situ hybridization.
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| Modi WS, et al.
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| Cytogenet Cell Genet 69 : 232-234. 1995
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| 29 | TYK2, JAK1
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| Characterization of a class 3 tyrosine kinase.
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| Howard OMZ, et al.
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| Oncogene 7 : 895-900. 1992
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| 30 | JAK1, JAK2
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| Two members of the JAK family of protein tyrosine kinases map to chromosomes 1p31.3 and 9p24.
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| Pritchard MA, et al.
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| Mamm Genome 3 : 36-38. 1992
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| 31 | JAK1, JAK2
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| Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.
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| Wilks AF, et al.
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| Mol Cell Biol 11 : 2057-2065. 1991
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