| 1 | DLL4, JAG1, NR4A1
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| DLL4 and Jagged1 are angiogenic targets of orphan nuclear receptor TR3/Nur77.
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| Peng J, Zhao S, Li Y, Niu G, Chen C, Ye T, Zhao D, Zeng H.
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| Microvasc Res 124:67-75. doi: 10.1016/j.mvr.2019.03.006. Epub 2019 Mar 28.
2019
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| 2 | JAG1, NOTCH1
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| Notch ligand Jagged1 promotes mesenchymal stromal cell-based cartilage repair.
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| Sun J, Luo Z, Wang G, Wang Y, Wang Y, Olmedo M, Morandi MM, Barton S, Kevil CG, Shu B, Shang X, Dong Y.
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| Exp Mol Med 50(9):126. doi: 10.1038/s12276-018-0151-9.
2018
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| 3 | JAG1, NOTCH2, TFAM
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| Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.
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| Huang S, Park J, Qiu C, Chung KW, Li SY, Sirin Y, Han SH, Taylor V, Zimber-Strobl U, Susztak K.
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| PLoS Biol 16(9):e2005233. doi: 10.1371/journal.pbio.2005233. eCollection 2018 Sep.
2018
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| 4 | JAG1, MFNG, NOTCH1
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| Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells.
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| López-Arribillaga E, Rodilla V, Colomer C, Vert A, Shelton A, Cheng JH, Yan B, Gonzalez-Perez A, Junttila MR, Iglesias M, Torres F, Albanell J, Villanueva A, Bigas A, Siebel CW, Espinosa L.
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| Nat Commun 9(1):2992. doi: 10.1038/s41467-018-05385-0.
2018
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| 5 | ALGS, JAG1
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| JAG1 loss‑of‑function mutations contributed to Alagille syndrome in two Chinese families.
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| Zhang E, Xu Y, Yu Y, Chen S, Yu Y, Sun K.
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| Mol Med Rep 18(2):2356-2364. doi: 10.3892/mmr.2018.9217. Epub 2018 Jun 25.
2018
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| 6 | ICHD, JAG1
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| Silencing mutations in JAG1 gene may play crucial roles in the pathogenesis of Tetralogy of Fallot.
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| Safari-Arababadi A, Behjati-Ardakani M, Kalantar SM, Jaafarinia M.
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| Cell Mol Biol (Noisy-le-grand) 64(4):103-107. 2018
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| 7 | ALGS, JAG1
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| Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.
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| Andersson ER, Chivukula IV, Hankeova S, Sjöqvist M, Tsoi YL, Ramsköld D, Masek J, Elmansuri A, Hoogendoorn A, Vazquez E, Storvall H, Netuilová J, Huch M, Fischler B, Ellis E, Contreras A, Nemeth A, Chien KC, Clevers H, Sandberg R, Bryja V, Lendahl U.
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| Gastroenterology 154(4):1080-1095. doi: 10.1053/j.gastro.2017.11.002. Epub 2017 Nov 21.
2018
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| 8 | DLL1, JAG1, NOTCH1
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| Both Notch1 and its ligands in B cells promote antibody production.
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| Zhu G, Wang X, Xiao H, Liu X, Fang Y, Zhai B, Xu R, Han G, Chen G, Hou C, Shen B, Li Y, Ma N, Wu H, Liu G, Wang R.
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| Mol Immunol 91:17-23. doi: 10.1016/j.molimm.2017.08.021. Epub 2017 Aug 31.
2017
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| 9 | JAG1, NOTCH3
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| Expression of Jagged1/Notch3 Signaling Pathway and their Relationship with the Tumor Angiogenesis in TNBC.
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| Xue S, He L, Zhang X, Zhou J, Li F, Wang X.
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| Arch Med Res 48(2):169-179. doi: 10.1016/j.arcmed.2017.03.014.
2017
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| 10 | JAG1, NOTCH2
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| Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear.
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| Teng CS, Yen HY, Barske L, Smith B, Llamas J, Segil N, Go J, Sanchez-Lara PA, Maxson RE, Crump JG.
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| Sci Rep 7(1):2497. doi: 10.1038/s41598-017-02574-7.
2017
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| 11 | DLL4, JAG1
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| Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.
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| Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL.
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| Oncotarget 8(25):40115-40131. doi: 10.18632/oncotarget.16969.
2017
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| 12 | JAG1
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| The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.
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| Lawal RA, Zhou X, Batey K, Hoffman CM, Georger MA, Radtke F, Hilton MJ, Xing L, Frisch BJ, Calvi LM.
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| J Bone Miner Res 32(6):1320-1331. doi: 10.1002/jbmr.3106. Epub 2017 Mar 9.
2017
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| 13 | GDNF, JAG1
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| The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells.
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| Garcia TX, Parekh P, Gandhi P, Sinha K, Hofmann MC.
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| Stem Cells Dev 26(8):585-598. doi: 10.1089/scd.2016.0318. Epub 2017 Jan 3.
2017
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| 14 | JAG1
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| Jagged1 expression by osteoblast-lineage cells regulates trabecular bone mass and periosteal expansion in mice.
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| Youngstrom DW, Dishowitz MI, Bales CB, Carr E, Mutyaba PL, Kozloff KM, Shitaye H, Hankenson KD, Loomes KM.
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| Bone 91:64-74. doi: 10.1016/j.bone.2016.07.006. Epub 2016 Jul 12.
2016
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| 15 | ALGS, JAG1
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| JAG1 Loss-Of-Function Variations as a Novel Predisposing Event in the Pathogenesis of Congenital Thyroid Defects.
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| de Filippis T, Marelli F, Nebbia G, Porazzi P, Corbetta S, Fugazzola L, Gastaldi R, Vigone MC, Biffanti R, Frizziero D, Mandarŕ L, Prontera P, Salerno M, Maghnie M, Tiso N, Radetti G, Weber G, Persani L.
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| J Clin Endocrinol Metab 101(3):861-70. doi: 10.1210/jc.2015-3403. Epub 2016 Jan 13.
2016
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| 16 | JAG1
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| Jagged1 (JAG1): Structure, expression, and disease associations.
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| Grochowski CM, Loomes KM, Spinner NB.
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| Gene 576(1 Pt 3):381-4. doi: 10.1016/j.gene.2015.10.065. Epub 2015 Nov 6. Review.
2016
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| 17 | DMD, JAG1
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| Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.
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| Vieira NM, Elvers I, Alexander MS, Moreira YB, Eran A, Gomes JP, Marshall JL, Karlsson EK, Verjovski-Almeida S, Lindblad-Toh K, Kunkel LM, Zatz M.
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| Cell 163(5):1204-1213. doi: 10.1016/j.cell.2015.10.049. Epub 2015 Nov 12.
2015
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| 18 | JAG1
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| Jagged1 intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart.
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| Metrich M, Bezdek Pomey A, Berthonneche C, Sarre A, Nemir M, Pedrazzini T.
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| Cardiovasc Res 108(1):74-86. doi: 10.1093/cvr/cvv209. Epub 2015 Aug 6.
2015
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| 19 | DLL1, JAG1
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| Disappearance of centroacinar cells in the Notch ligand-deficient pancreas.
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| Nakano Y, Negishi N, Gocho S, Mine T, Sakurai Y, Yazawa M, Abe K, Yagita H, Habu S, Kageyama R, Kawaguchi Y, Hozumi K.
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| Genes Cells 20(6):500-11. doi: 10.1111/gtc.12243. Epub 2015 Apr 27.
2015
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| 20 | JAG1, SOX9
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| Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.
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| Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML.
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| Dev Cell 31(6):707-21. doi: 10.1016/j.devcel.2014.11.023.
2014
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| 21 | BACE1, JAG1, JAG2
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| β-site amyloid precursor protein cleaving enzyme 1(BACE1) regulates Notch signaling by controlling the cleavage of Jagged 1 (Jag1) and Jagged 2 (Jag2) proteins.
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| He W, Hu J, Xia Y, Yan R.
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| J Biol Chem. Jul 25;289(30):20630-7. doi: 10.1074/jbc.M114.579862. 2014
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| 22 | JAG1
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| Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus.
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| Lavado A, Oliver G.
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| Dev Biol 388(1):11-21. doi: 10.1016/j.ydbio.2014.02.004. Epub 2014 Feb 13.
2014
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| 23 | JAG1, JAG2
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| NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma
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| Fiaschetti G, Schroeder C, Castelletti D, Arcaro A, Westermann F, Baumgartner M, Shalaby T, Grotzer MA.
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| Acta Neuropathol Commun. Apr 7;2:39. doi: 10.1186/2051-5960-2-39. 2014
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| 24 | JAG1, NOTCH3
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| Overexpression of the Notch3 receptor and its ligand Jagged1 in human clinically non-functioning pituitary adenomas.
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| Lu R, Gao H, Wang H, Cao L, Bai J, Zhang Y.
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| Oncol Lett 5(3):845-851. Epub 2013 Jan 7.
2013
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| 25 | JAG1
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| Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways.
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| Zhang S, Loch AJ, Radtke F, Egan SE, Xu K.
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| Dev Dyn 242(6):678-86. doi: 10.1002/dvdy.23965. Epub 2013 Apr 29.
2013
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| 26 | ALGS, JAG1
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| Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.
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| Hofmann JJ, Briot A, Enciso J, Zovein AC, Ren S, Zhang ZW, Radtke F, Simons M, Wang Y, Iruela-Arispe ML.
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| Development 139(23):4449-60. doi: 10.1242/dev.084871. Epub 2012 Oct 24.
2012
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| 27 | JAG1, JAG2
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| Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.
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| Van de Walle I, De Smet G, Gärtner M, De Smedt M, Waegemans E, Vandekerckhove B, Leclercq G, Plum J, Aster JC, Bernstein ID, Guidos CJ, Kyewski B, Taghon T.
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| Blood 117(17):4449-59. Epub 2011 Mar 3.
2011
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| 28 | AFDN, JAG1
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| The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation.
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| Popovic M, Bella J, Zlatev V, Hodnik V, Anderluh G, Barlow PN, Pintar A, Pongor S.
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| J Mol Recognit 24(2):245-53. doi: 10.1002/jmr.1042. 2011
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| 29 | JAG1
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| Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.
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| Kung AW, Xiao SM, Cherny S, Li GH, Gao Y, Tso G, Lau KS, Luk KD, Liu JM, Cui B, Zhang MJ, Zhang ZL, He JW, Yue H, Xia WB, Luo LM, He SL, Kiel DP, Karasik D, Hsu YH, Cupples LA, Demissie S, Styrkarsdottir U, Halldorsson BV, Sigurdsson G, Thorsteinsdottir U, Stefansson K, Richards JB, Zhai G, Soranzo N, Valdes A, Spector TD, Sham PC.
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| Am J Hum Genet 86(2):229-39. Epub 2010 Jan 21.PMID: 20096396 2010
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| 30 | CNN1, JAG1, MYCD
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| TGF-beta and Notch Signaling Mediate Stem Cell Differentiation into Smooth Muscle Cells.
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| Kurpinski K, Lam H, Chu J, Wang A, Kim A, Tsay E, Agrawal S, Schaffer D, Li S.
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| Stem Cells tem Cells. 2010 Feb 9. [Epub ahead of print]PMID: 20146266 2010
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| 31 | CSX, CTHM1, DEL22Q11, ICHD, JAG1, NKX2-5, TBX1, TRI21
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| Comprehensive genotype-phenotype analysis in 230 patients with tetralogy of Fallot.
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| Rauch R, Hofbeck M, Zweier C, Koch A, Zink S, Trautmann U, Hoyer J, Kaulitz R, Singer H, Rauch A.
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| J Med Genet 47(5):321-31. Epub 2009 Nov 30.PMID: 19948535 2010
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| 32 | ADAM17, JAG1
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| Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event.
|
| Parr-Sturgess CA, Rushton DJ, Parkin ET.
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| Biochem J 432(2):283-94.
2010
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| 33 | BMP2, DEL20P12, JAG1, WPW2
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| 20p12.3 microdeletion predisposes to Wolff-Parkinson-White syndrome with variable neurocognitive deficits.
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| Lalani SR, Thakuria JV, Cox GF, Wang X, Bi W, Bray MS, Shaw C, Cheung SW, Chinault AC, Boggs BA, Ou Z, Brundage EK, Lupski JR, Gentile J, Waisbren S, Pursley A, Ma L, Khajavi M, Zapata G, Friedman R, Kim JJ, Towbin JA, Stankiewicz P, Schnittger S, Hansmann I, Ai T, Sood S, Wehrens XH, Martin JF, Belmont JW, Potocki L.
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| J Med Genet 46(3):168-75. Epub 2008 Sep 23.
2009
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| 34 | ALGS, DEL20P12, JAG1
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| SNP array mapping of chromosome 20p deletions: genotypes, phenotypes, and copy number variation.
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| Kamath BM, Thiel BD, Gai X, Conlin LK, Munoz PS, Glessner J, Clark D, Warthen DM, Shaikh TH, Mihci E, Piccoli DA, Grant SF, Hakonarson H, Krantz ID, Spinner NB.
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| Hum Mutat 30(3):371-8.
2009
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| 35 | JAG1
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| Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.
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| Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V, Grilli A, López-Bigas N, Bellora N, Albŕ MM, Torres F, Duńach M, Sanjuan X, Gonzalez S, Gridley T, Capella G, Bigas A, Espinosa L.
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| Proc Natl Acad Sci U S A 106(15):6315-20. Epub 2009 Mar 26.
2009
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| 36 | JAG1, JAG2
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| Distinct biological roles for the notch ligands Jagged-1 and Jagged-2.
|
| Choi K, Ahn YH, Gibbons DL, Tran HT, Creighton CJ, Girard L, Minna JD, Qin FX, Kurie JM.
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| J Biol Chem 284(26):17766-74. Epub 2009 Apr 27.
2009
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| 37 | DLL4, JAG1
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| The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis.
|
| Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M, Adams RH.
|
| Cell 137(6):1124-35.
2009
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| 38 | ASD2, ASD3, GATA4, ICHD, JAG1, MYH6, NKX2-5, NOTCH1, TBX1, TBX20, TBX5, TFAP2B, THRAP2
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| The developmental genetics of congenital heart disease.
|
| Bruneau BG.
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| Nature 451(7181):943-8. 2008
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| 39 | NOTCH1, NOTCH2, NOTCH3, JAG1, ICHD, PSEN1, PSEN2
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| The multifaceted role of Notch in cardiac development and disease.
|
| High FA, Epstein JA.
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| Nat Rev Genet 9(1):49-61. Review. 2008
|
| 40 | JAG1
|
| Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development.
|
| High FA, Lu MM, Pear WS, Loomes KM, Kaestner KH, Epstein JA.
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| Proc Natl Acad Sci U S A 105(6):1955-9. Epub 2008 Feb 1. 2008
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| 41 | JAG1, ALGS
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| Absence of NOTCH2 and Hey2 mutations in a familial Alagille syndrome case with a novel frameshift mutation in JAG1.
|
| El-Rassy I, Bou-Abdallah J, Al-Ghadban S, Bitar F, Nemer G.
|
| Am J Med Genet A 146(7):937-9. No abstract available. 2008
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| 42 | BMP2, DEL20P12, JAG1, WPW2
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| A 8.26Mb deletion in 6q16 and a 4.95Mb deletion in 20p12 including JAG1 and BMP2 in a patient with Alagille syndrome and Wolff-Parkinson-White syndrome.
|
| Le Gloan L, Pichon O, Isidor B, Boceno M, Rival JM, David A, Le Caignec C.
|
| Eur J Med Genet 51(6):651-7. Epub 2008 Aug 15.PMID: 18775522 2008
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| 43 | ALGS, JAG1
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| Alagille syndrome with deletion 20p12.2-p12.3 and hypoplastic left heart.
|
| Robert ML, Lopez T, Crolla J, Huang S, Owen C, Burvill-Holmes L, Stumper O, Turnpenny PD.
|
| Clin Dysmorphol 16(4):241-246. 2007
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| 44 | ALGS, JAG1
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| Biological function of mutant forms of JAGGED1 proteins in Alagille syndrome: inhibitory effect on Notch signaling.
|
| Ponio JB, Wright-Crosnier C, Groyer-Picard MT, Driancourt C, Beau I, Hadchouel M, Meunier-Rotival M.
|
| Hum Mol Genet [Epub ahead of print] 2007
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| 45 | JAG1, ALGS
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| Human Jagged 1 mutants cause liver defect in Alagille syndrome by overexpression of hepatocyte growth factor.
|
| Yuan ZR, Kobayashi N, Kohsaka T.
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| J Mol Biol 356(3):559-68. Epub 2005 Dec 20. 2006
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| 46 | JAG1
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| Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
|
| Katoh M, Katoh M.
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| Int J Mol Med 17(4):681-5. 2006
|
| 47 | JAG1
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| Gene synthesis, expression, purification, and characterization of human Jagged-1 intracellular region.
|
| Popovic M, Coglievina M, Guarnaccia C, Verdone G, Esposito G, Pintar A, Pongor S.
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| Protein Expr Purif 47(2):398-404. Epub 2005 Dec 28. 2006
|
| 48 | JAG1, ALGS
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| Ozzy, a Jag1 vestibular mouse mutant, displays characteristics of Alagille syndrome.
|
| Vrijens K, Thys S, De Jeu MT, Postnov AA, Pfister M, Cox L, Zwijsen A, Van Hoof V, Mueller M, De Clerck NM, De Zeeuw CI, Van Camp G, Van Laer L.
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| Neurobiol Dis 24(1):28-40. Epub 2006 Jul 26. 2006
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| 49 | JAG1, ALGS
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| Expression of mutant JAGGED1 alleles in patients with Alagille syndrome.
|
| Boyer J, Crosnier C, Driancourt C, Raynaud N, Gonzales M, Hadchouel M, Meunier-Rotival M.
|
| Hum Genet 116(6):445-53. Epub 2005 Mar 17. 2005
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| 50 | GLI3,JAG1,PAX9
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| Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.
|
| McGlinn E, van Bueren KL, Fiorenza S, Mo R, Poh AM, Forrest A, Soares MB, Bonaldo Mde F, Grimmond S, Hui CC, Wainwright B, Wicking C.
|
| Mech Dev 122(11):1218-33. Epub 2005 Aug 1. 2005
|
| 51 | CADASIL, NOTCH3, JAG1
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| Pathogenic Mutations Associated with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Differently Affect Jagged1 Binding and Notch3 Activity via the RBP/JK Signaling Pathway.
|
| Joutel A, Monet M, Domenga V, Riant F, Tournier-Lasserve E.
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| Am J Hum Genet 74(2):338-47. Epub 2004 Jan 08. 2004
|
| 52 | CADASIL, DLL1, Dll3, DLL4, JAG1, JAG2, NOTCH1, NOTCH2, NOTCH3, NOTCH4 , RBPJ, SCDO1
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| Notch signaling and inherited disease syndromes.
|
| Gridley T.
|
| Hum Mol Genet 12 Spec No 1:R9-13. Review. 2003
|
| 53 | JAG1, ALGS
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| Consequences of JAG1 mutations.
|
| Kamath BM, Bason L, Piccoli DA, Krantz ID, Spinner NB.
|
| J Med Genet 40(12):891-5. 2003
|
| 54 | JAG1, ICHD
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| Conditional JAG1 mutation shows the developing heart is more sensitive than developing liver to JAG1 dosage.
|
| Lu F, Morrissette JJ, Spinner NB.
|
| Am J Hum Genet 72(4):1065-70. Epub 2003 Mar 14. 2003
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| 55 | JAG1
|
| Familial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1.
|
| Le Caignec C, Lefevre M, Schott JJ, Chaventre A, Gayet M, Calais C, Moisan JP.
|
| Am J Hum Genet 71(1):180-6. 2002
|
| 56 | JAG1
|
| The Notch ligand Jagged1 is required for inner ear sensory development.
|
| Kiernan AE, Ahituv N, Fuchs H, Balling R, Avraham KB, Steel KP, Hrabe de Angelis M.
|
| Proc Natl Acad Sci U S A 98(7):3873-8. 2001
|
| 57 | ALGS, JAG1
|
| The DSL domain in mutant JAG1 ligand is essential for the severity of the liver defect in Alagille syndrome.
|
| Yuan Z, Okaniwa M, Nagata I, Tazawa Y, Ito M, Kawarazaki H, Inomata Y, Okano S, Yoshida T, Kobayashi N, Kohsaka T.
|
| Clin Genet 59(5):330-337. 2001
|
| 58 | ALGS, JAG1
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| Parental mosaicism of JAG1 mutations in families with Alagille syndrome.
|
| Giannakudis J, Ropke A, Kujat A, Krajewska-Walasek M, Hughes H, Fryns JP, Bankier A, Amor D, Schlicker M, Hansmann I.
|
| Eur J Hum Genet 9(3):209-16. 2001
|
| 59 | JAG1
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| Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome.
|
| Morrissette JD, Colliton RP, Spinner NB.
|
| Hum Mol Genet 10(4):405-13. 2001
|
| 60 | JAG1, ICHD
|
| Familial Tetralogy of Fallot caused by mutation in the jagged1 gene.
|
| Eldadah ZA, Hamosh A, Biery NJ, Montgomery RA, Duke M, Elkins R, Dietz HC.
|
| Hum Mol Genet 10(2):163-9. 2001
|
| 61 | JAG1
|
| The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti.
|
| Tsai H, Hardisty RE, Rhodes C, Kiernan AE, Roby P, Tymowska-Lalanne Z, Mburu P, Rastan S, Hunter AJ, Brown SD, Steel KP.
|
| Hum Mol Genet 10(5):507-12. 2001
|
| 62 | ALGS, JAG1
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| Jagged1 (JAG1) mutation detection in an australian alagille syndrome population.
|
| Heritage ML, MacMillan JC, Colliton RP, Genin A, Spinner NB, Anderson GJ.
|
| Hum Mutat 16(5):408-16. 2000
|
| 63 | ALGS, JAG1
|
| JAGGED1 expression in human embryos : correlation with the Alagille syndrome phenotype.
|
| Jones EA, Clement-Jones M, Wilson DI.
|
| J Med Genet 37 : 658-662. 2000
|
| 64 | JAG1
|
| JAGGED1 gene expression during human embryogenesis elucidates the wide phenotypic spectrum of Alagille syndrome.
|
| Crosnier C, Attie-Bitach T, Encha-Razavi F, Audollent S, Soudy F, Hadchouel M, Meunier-Rotival M, Vekemans M.
|
| Hepatology 32(3):574-81. 2000
|
| 65 | JAG1
|
| Embryonic lethality and vascular defects in mice lacking the notch ligand jagged1.
|
| Xue Y, et al.
|
| Hum Mol Genet 8(5):723-30. 1999
|
| 66 | JAG1, NFKB1, NFKB2, REL
|
| Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors.
|
| Bash J, et al.
|
| EMBO J 18(10):2803-2811. 1999
|
| 67 | ALGS, JAG1
|
| The expression of jagged1 in the developing mammalian heart correlates with cardiovascular disease in alagille syndrome.
|
| Loomes KM, Underkoffler LA, Morabito J, Gottlieb S, Piccoli DA, Spinner NB, Baldwin HS, Oakey RJ.
|
| Hum Mol Genet 8(13):2443-9 1999
|
| 68 | DLK1, JAG1
|
| Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear.
|
| Morrison A, Hodgetts C, Gossler A, Hrabe de Angelis M, Lewis J.
|
| Mech Dev 84(1-2):169-72. 1999
|
| 69 | ALGS, JAG1, TTGT
|
| Jagged1 mutations in patients ascertained with isolated congenital heart defects.
|
| Krantz ID, Smith R, Colliton RP, Tinkel H, Zackai EH, Piccoli DA, Goldmuntz E, Spinner NB.
|
| Am J Med Genet 84(1):56-60. 1999
|
| 70 | ALGS, JAG1
|
| Spectrum and frequency of Jagged1 (JAG1) mutations in Alagille syndrome patients and their families.
|
| Krantz ID, et al.
|
| Am J Hum Genet 62 : 1361-1369. 1998
|
| 71 | ALGS, JAG1
|
| Mutational analysis of the Jagged 1 gene in Alagille syndrome families.
|
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