1 | IVL, PRKCD, PRKCD, WDR77
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| MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.
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| Saha K, Adhikary G, Eckert RL.
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| J Invest Dermatol 136(1):214-24. doi: 10.1038/JID.2015.400.
2016
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2 | IVL, LOR
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| Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6.
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| Kim BE, Leung DY, Boguniewicz M, Howell MD.
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| Clin Immunol 126(3):332-7. Epub 2007 Dec 31. 2008
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3 | EVPL, IVL, PPL
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| Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier.
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| Sevilla LM, Nachat R, Groot KR, Klement JF, Uitto J, Djian P, Määttä A, Watt FM.
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| J Cell Biol 179(7):1599-612.
2007
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4 | IVL, POU2F2
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| The human involucrin gene is transcriptionally repressed through a tissue-specific silencer element recognized by Oct-2.
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| Azuara-Liceaga E, Sandoval M, Corona M, Gariglio P, Lopez-Bayghen E.
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| Biochem Biophys Res Commun 318(2):361-71. 2004
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5 | CREBBP, IVL, KAT2B
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| Regulation of the human involucrin gene promoter by co-activator proteins.
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| Tran NQ, Crowe DL.
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| Biochem J 381(Pt 1):267-73. 2004
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6 | IVL
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| Transactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF).
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| Kubo E, Fatma N, Sharma P, Shinohara T, Chylack LT Jr, Akagi Y, Singh DP.
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| J Mol Biol 320(5):1053-63. 2002
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7 | IVL
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| The human involucrin gene contains spatially distinct regulatory elements that regulate expression during early versus late epidermal differentiation.
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| Crish JF, Bone F, Banks EB, Eckert RL.
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| Oncogene 21(5):738-47. Erratum in: Oncogene 2002 May 23;21(23):3826. 2002
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8 | TGM1, IVL, NCIE1
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| A novel function for transglutaminase 1: attachment of long-chain omega-hydroxyceramides to involucrin by ester bond formation.
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| Nemes Z, Marekov LN, Fesus L, Steinert PM.
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| Proc Natl Acad Sci U S A 96(15):8402-7. 1999
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9 | FLG, IVL, LOR, S100A10, S100A6, S100A8, S100A9, SPRR1B, SPRR2A, SPRR3, TCHH
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| Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex (epidermal differentiation complex) on human chromosome 1q21.
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| Mischke D, Korge BP, Marenholz I, Volz A, Ziegler A.
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| J Invest Dermatol 106 : 989-992. 1996
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10 | FLG, IVL, S100A10
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| Physical mapping of a functional cluster of epidermal differentiation genes on chromosome 1q21.
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| Volz A, et al.
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| Genomics 18 : 92-99. 1993
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11 | FLG, TCHH, IVL, LOR
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| Mapping of the trichohyalin gene : co-localization with the profilaggrin, involucrin, and loricrin genes.
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| Fietz MJ, et al.
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| J Invest Dermatol 99 : 542-544. 1992
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12 | IVL
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| Polymorphism due to variable number of repeats in the human involucrin gene.
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| Simon M, et al.
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| Genomics 9 : 576-580. 1991
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13 | IVL
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| Chromosomal mapping of the human involucrin gene (IVL).
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| Stroh H, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 700. 1987
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14 | IVL
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| Structure and evolution of the human involucrin gene.
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| Eckert RL, et al.
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| Cell 46 : 583-589. 1986
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