Citations for
1ADAM7, CANX, HSPA5, ITM2B
Identification of heat shock protein 5, calnexin and integral membrane protein 2B as Adam7-interacting membrane proteins in mouse sperm.
Han C, Park I, Lee B, Jin S, Choi H, Kwon JT, Kwon YI, Kim do H, Park ZY, Cho C.
J Cell Physiol 226(5):1186-95. doi: 10.1002/jcp.22444. 2011
2ITM2B
BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE).
Kilger E, Buehler A, Woelfing H, Kumar S, Kaeser SA, Nagarathinam A, Walter J, Jucker M, Coomaraswamy J.
J Biol Chem 286(43):37446-57. Epub 2011 Aug 26. 2011
3FBD, ITM2B
Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis.
Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, Vidal R, D'Adamio L.
J Neurosci 30(44):14915-24. 2010
4ITM2B
Bri2-23 is a potential cerebrospinal fluid biomarker in multiple sclerosis.
Harris VK, Diamanduros A, Good P, Zakin E, Chalivendra V, Sadiq SA.
Neurobiol Dis 40(1):331-9. Epub 2010 Jun 19. 2010
5ITM2B
The extracellular domain of Bri2 (ITM2B) binds the ABri peptide (1-23) and amyloid beta-peptide (Abeta1-40): Implications for Bri2 effects on processing of amyloid precursor protein and Abeta aggregation.
Peng S, Fitzen M, Jörnvall H, Johansson J.
Biochem Biophys Res Commun 393(3):356-61. Epub 2009 Dec 28. 2010
6ITM2B
BRI2 homodimerizes with the involvement of intermolecular disulfide bonds.
Tsachaki M, Ghiso J, Rostagno A, Efthimiopoulos S.
Neurobiol Aging 31(1):88-98. Epub 2008 Apr 28. 2010
7ITM2B, ITM2C
BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.
Matsuda S, Matsuda Y, D'Adamio L.
J Biol Chem 284(23):15815-25. Epub 2009 Apr 14. 2009
8ITM2B, SPPL2A
Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
Martin L, Fluhrer R, Reiss K, Kremmer E, Saftig P, Haass C.
J Biol Chem 283(3):1644-52. Epub 2007 Oct 25. 2008
9FBD, ITM2B
Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease.
Lashley T, Revesz T, Plant G, Bandopadhyay R, Lees AJ, Frangione B, Wood NW, de Silva R, Ghiso J, Rostagno A, Holton JL.
Neuropathol Appl Neurobiol 34(5):492-505. Epub 2008 Feb 13. 2008
10ITM2B
Expression and regulation of type II integral membrane protein family members in mouse male reproductive tissues.
Rengaraj D, Gao F, Liang XH, Yang ZM.
Endocrine 31(2):193-201. 2007
11FBD, FDD, ITM2B
Genetic alterations of the BRI2 gene: familial British and Danish dementias.
Ghiso J, Rostagno A, Tomidokoro Y, Lashley T, Bojsen-M¿ller M, Braendgaard H, Plant G, Holton J, Lal R, Revesz T, Frangione B.
Brain Pathol 16(1):71-9. 2006
12FBD,FDD,ITM2B
Chromosome 13 dementias.
Rostagno A, Tomidokoro Y, Lashley T, Ng D, Plant G, Holton J, Frangione B, Revesz T, Ghiso J.
Cell Mol Life Sci 62(16):1814-25. Review. 2005
13ITM2B, FBD
Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain.
Akiyama H, Kondo H, Arai T, Ikeda K, Kato M, Iseki E, Schwab C, McGeer PL.
Acta Neuropathol (Berl) 107(1):53-8. Epub 2003 Oct 29. 2004
14TSG13A, TSG13B, TSG13D, ITM2B, RCBTB2, FNDC3A
Extensive analysis of the 13q14 region in human prostate tumors: DNA analysis and quantitative expression of genes lying in the interval of deletion.
Latil A, Chene L, Mangin P, Fournier G, Berthon P, Cussenot O.
Prostate 57(1):39-50. 2003
15ITM2B, BRI3, ITM2C
Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family.
Vidal R, Calero M, Revesz T, Plant G, Ghiso J, Frangione B.
Gene 266(1-2):95-102. 2001
16ITM2B, FDD
A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred.
Vidal R, Revesz T, Rostagno A, Kim E, Holton JL, Bek T, Bojsen-Moller M, Braendgaard H, Plant G, Ghiso J, Frangione B.
Proc Natl Acad Sci U S A 97(9):4920-5. 2000
17ITM2B, FBD
A stop-codon mutation in the BRI gene associated with familial British dementia.
Vidal R, et al.
Nature 399(6738):776-81. 1999
18ITM2B
cDNA sequence analysis, chromosomal assignment and expression pattern of the gene coding for integral membrane protein 2B.
Pittois K, et al.
Gene 217 : 141-149. 1998