Citations for
1GT2, GT3, ITGA2B, ITGB3
ITGA2B and ITGB3 gene mutations associated with Glanzmann thrombasthenia.
Nurden AT, Pillois X.
Platelets 29(1):98-101. doi: 10.1080/09537104.2017.1371291. Epub 2017 Nov 10. Review. No abstract available. 2018
2FLNA, ITGA2B, ITGB3
Gain-of-Function Mutation in Filamin A Potentiates Platelet Integrin αIIbβ3 Activation.
Berrou E, Adam F, Lebret M, Planche V, Fergelot P, Issertial O, Coupry I, Bordet JC, Nurden P, Bonneau D, Colin E, Goizet C, Rosa JP, Bryckaert M.
Arterioscler Thromb Vasc Biol 37(6):1087-1097. doi: 10.1161/ATVBAHA.117.309337. Epub 2017 Apr 20. 2017
3ITGA2B, ITGB3
Identification of ITGA2B and ITGB3 Single-Nucleotide Polymorphisms and Their Influences on the Platelet Function.
Xiang Q, Ji SD, Zhang Z, Zhao X, Cui YM.
Biomed Res Int 2016:5675084. Epub 2016 Nov 14. 2016
4ITGA2B, ITGB3
Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function.
Lu Z, Mathew S, Chen J, Hadziselimovic A, Palamuttam R, Hudson BG, Fässler R, Pozzi A, Sanders CR, Zent R.
Elife 5. pii: e18633. doi: 10.7554/eLife.18633. 2016
5ITGA2B, ITGB3
The Platelet Integrin αIIbβ3 Differentially Interacts with Fibrin Versus Fibrinogen.
Litvinov RI, Farrell DH, Weisel JW, Bennett JS.
J Biol Chem 291(15):7858-67. doi: 10.1074/jbc.M115.706861. Epub 2016 Feb 10. 2016
6DAB2, ITGB3
Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force.
Yu CH, Rafiq NB, Cao F, Zhou Y, Krishnasamy A, Biswas KH, Ravasio A, Chen Z, Wang YH, Kawauchi K, Jones GE, Sheetz MP.
Nat Commun 6:8672. doi: 10.1038/ncomms9672. 2015
7ITGB3
Matrix rigidity regulates the transition of tumor cells to a bone-destructive phenotype through integrin β3 and TGF-β receptor type II.
Page JM, Merkel AR, Ruppender NS, Guo R, Dadwal UC, Cannonier SA, Basu S, Guelcher SA, Sterling JA.
Biomaterials 64:33-44. doi: 10.1016/j.biomaterials.2015.06.026. Epub 2015 Jun 16. 2015
8ITGB3
ß3-integrin inhibits lipopolysaccharide-induced autophagy in cardiomyocytes via the Akt signaling pathway.
Zhu Y, Li L, Gong S, Yu Y, Dai H, Cai G, Yan J.
Cardiology 130(4):249-59. 2015
9FERMT3, ITGB3
Site-specific phosphorylation of kindlin-3 protein regulates its capacity to control cellular responses mediated by integrin αIIbβ3.
Bialkowska K, Byzova TV, Plow EF.
J Biol Chem 290(10):6226-42. doi: 10.1074/jbc.M114.634436. Epub 2015 Jan 21. 2015
10CDK11A, ITGB3
CDK11p58 inhibits ERα-positive breast cancer invasion by targeting integrin β3 via the repression of ERα signaling.
Chi Y, Huang S, Wang L, Zhou R, Wang L, Xiao X, Li D, Cai Y, Zhou X, Wu J.
BMC Cancer 14:577. doi: 10.1186/1471-2407-14-577. 2014
11ITGB3
Endometrial beta3 integrin profile reflects endometrial receptivity defects in women with unexplained recurrent pregnancy loss.
Germeyer A, Savaris RF, Jauckus J, Lessey B.
Reprod Biol Endocrinol 12:53. doi: 10.1186/1477-7827-12-53. 2014
12ITGB3
Vascular endothelial cells promote cortical neurite outgrowth via an integrin β3-dependent mechanism.
Sumimoto S, Muramatsu R, Fujii S, Yamashita T.
Biochem Biophys Res Commun 450(1):593-7. doi: 10.1016/j.bbrc.2014.06.012. Epub 2014 Jun 10. 2014
13ITGB3, SLC6A4
Serotonin transporter and integrin beta 3 genes interact to modulate serotonin uptake in mouse brain.
Whyte A, Jessen T, Varney S, Carneiro AM.
Neurochem Int 73:122-6. doi: 10.1016/j.neuint.2013.09.014. Epub 2013 Sep 29. 2014
14FYB1, ITGA2B, ITGB3, SKAP1
ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding.
Kasirer-Friede A, Kang J, Kahner B, Ye F, Ginsberg MH, Shattil SJ.
Blood 123(20):3156-65. doi: 10.1182/blood-2013-08-520627. Epub 2014 Feb 12. 2014
15ITGA2B, ITGB3
The interaction of integrin αIIbβ3 with fibrin occurs through multiple binding sites in the αIIb β-propeller domain.
Podolnikova NP, Yakovlev S, Yakubenko VP, Wang X, Gorkun OV, Ugarova TP.
J Biol Chem 289(4):2371-83. doi: 10.1074/jbc.M113.518126. Epub 2013 Dec 12. 2014
16ITGB3, SKIL
PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism.
Li C, Peart N, Xuan Z, Lewis DE, Xia Y, Jin J.
Cell Signal 26(7):1369-78. doi: 10.1016/j.cellsig.2014.03.006. Epub 2014 Mar 15. 2014
17ITGB3, SPRY4
Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src.
Gong Y, Yang X, He Q, Gower L, Prudovsky I, Vary CP, Brooks PC, Friesel RE.
Angiogenesis 16(4):861-75. doi: 10.1007/s10456-013-9361-x. Epub 2013 Aug 17. 2013
18ITGB3
Structural insights into the recognition of β3 integrin cytoplasmic tail by the SH3 domain of Src kinase.
Katyal P, Puthenveetil R, Vinogradova O.
Protein Sci 22(10):1358-65. doi: 10.1002/pro.2323. Epub 2013 Sep 4. 2013
19ITGA2B, ITGB3
Serine/threonine phosphatases regulate platelet αIIbβ3 integrin receptor outside-in signaling mechanisms and clot retraction.
Moscardó A, Santos MT, Latorre A, Madrid I, Vallés J.
Life Sci 93(20):707-13. doi: 10.1016/j.lfs.2013.09.020. Epub 2013 Oct 1. 2013
20ITGA2B, ITGB3
Activation induced morphological changes and integrin αIIbβ3 activity of living platelets.
Posch S, Neundlinger I, Leitner M, Siostrzonek P, Panzer S, Hinterdorfer P, Ebner A.
Methods 60(2):179-85. doi: 10.1016/j.ymeth.2013.03.034. Epub 2013 Apr 6. 2013
21ITGA2B, ITGB3
Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate.
Vara DS, Campanella M, Canobbio I, Dunn WB, Pizzorno G, Hirano M, Pula G.
Thromb Haemost 109(6):1108-19. doi: 10.1160/TH12-10-0751. Epub 2013 Mar 14. 2013
22ITGA2B, ITGB3, PTK2B
The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling.
Cipolla L, Consonni A, Guidetti G, Canobbio I, Okigaki M, Falasca M, Ciraolo E, Hirsch E, Balduini C, Torti M.
J Thromb Haemost 11(2):345-56. doi: 10.1111/jth.12099. 2013
23FGF2, HOXA10, ITGB3
HoxA10 protein regulates transcription of gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells.
Shah CA, Bei L, Wang H, Platanias LC, Eklund EA.
J Biol Chem 287(22):18230-48. doi: 10.1074/jbc.M111.328401. Epub 2012 Apr 4. 2012
24ITGB3
Requirement of integrin β3 for iron transportation during enamel formation.
Yoshida T, Kumashiro Y, Iwata T, Ishihara J, Umemoto T, Shiratsuchi Y, Kawashima N, Sugiyama T, Yamato M, Okano T.
J Dent Res 91(12):1154-9. doi: 10.1177/0022034512462722. Epub 2012 Oct 12. 2012
25ITGA2B, ITGB3
Clinical disability progression and platelet GP IIb/IIIa values in patients with atopic myelitis.
Ainiding G, Yamashita K, Torii T, Furuta K, Isobe N, Matsushita T, Masaki K, Matsumoto S, Kira J.
J Neuroimmunol 246(1-2):108-12. doi: 10.1016/j.jneuroim.2012.03.009. Epub 2012 Apr 5. 2012
26GT3, ITGB3
Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models.
Nurden AT, Fiore M, Nurden P, Pillois X.
Blood 118(23):5996-6005. doi: 10.1182/blood-2011-07-365635. Epub 2011 Sep 13. Review. 2011
27ITGA2B, ITGB3
Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia.
Kunishima S, Kashiwagi H, Otsu M, Takayama N, Eto K, Onodera M, Miyajima Y, Takamatsu Y, Suzumiya J, Matsubara K, Tomiyama Y, Saito H.
Blood 117(20):5479-84. doi: 10.1182/blood-2010-12-323691. Epub 2011 Mar 31. 2011
28ITGA2B, ITGB3
CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells.
Robin C, Ottersbach K, Boisset JC, Oziemlak A, Dzierzak E.
Blood 117(19):5088-91. doi: 10.1182/blood-2011-01-329516. Epub 2011 Mar 17. 2011
29ITGB3, SLC6A4
Association and gene-gene interaction of SLC6A4 and ITGB3 in autism.
Ma DQ, Rabionet R, Konidari I, Jaworski J, Cukier HN, Wright HH, Abramson RK, Gilbert JR, Cuccaro ML, Pericak-Vance MA, Martin ER.
Am J Med Genet B Neuropsychiatr Genet 153B(2):477-83.PMID: 19588468 2010
30GT3, ITGB3
AlphaIIbbeta3 integrin: new allelic variants in Glanzmann thrombasthenia, effects on ITGA2B and ITGB3 mRNA splicing, expression, and structure-function.
Jallu V, Dusseaux M, Panzer S, Torchet MF, Hezard N, Goudemand J, de Brevern AG, Kaplan C.
Hum Mutat 31(3):237-46.PMID: 20020534 2010
31ITGA2B, ITGB3
Predictive value of platelet activation for the rate of cognitive decline in Alzheimer's disease patients.
Stellos K, Panagiota V, Kögel A, Leyhe T, Gawaz M, Laske C.
J Cereb Blood Flow Metab 30(11):1817-20. Epub 2010 Aug 18.PMID: 20717123 2010
32ITGA2B, ITGB3
Dynamic regulation of fibrinogen: integrin αIIbβ3 binding.
Hantgan RR, Stahle MC, Lord ST.
Biochemistry 49(43):9217-25. doi: 10.1021/bi1009858. 2010
33ITGA2B, ITGB3
A unique interaction between alphaIIb and beta3 in the head region is essential for outside-in signaling-related functions of alphaIIbbeta3 integrin.
Hauschner H, Landau M, Seligsohn U, Rosenberg N.
Blood 115(22):4542-50. doi: 10.1182/blood-2009-10-251066. Epub 2010 Mar 22. 2010
34ITGB3
Proapoptotic function of integrin beta(3) in human hepatocellular carcinoma cells.
Wu Y, Zuo J, Ji G, Saiyin H, Liu X, Yin F, Cao N, Wen Y, Li JJ, Yu L.
Clin Cancer Res 15(1):60-9.PMID: 19118033 2009
35ITGA2B, ITGB3
Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Yang J, Ma YQ, Page RC, Misra S, Plow EF, Qin J.
Proc Natl Acad Sci U S A 106(42):17729-34. doi: 10.1073/pnas.0909589106. Epub 2009 Oct 1. 2009
36ITGA2B, ITGB3
Evidence that integrin alpha IIb beta 3-dependent interaction of mast cells with fibrinogen exacerbates chronic inflammation.
Oki T, Eto K, Izawa K, Yamanishi Y, Inagaki N, Frampton J, Kitamura T, Kitaura J.
J Biol Chem 284(45):31463-72. doi: 10.1074/jbc.M109.030213. Epub 2009 Sep 15. 2009
37FOXC2, ITGB3
The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression.
Hayashi H, Sano H, Seo S, Kume T.
J Biol Chem 283(35):23791-800. Epub 2008 Jun 24. 2008
38GPNMB, ITGB1, ITGB3
Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.
Sheng MH, Wergedal JE, Mohan S, Lau KH.
FEBS Lett 582(10):1451-8. Epub 2008 Mar 31. 2008
39ITGA2B, ITGB3
Factor H binds to platelet integrin alphaIIbbeta3.
Mnjoyan Z, Li J, Afshar-Kharghan V.
Platelets 19(7):512-9. doi: 10.1080/09537100802238494. 2008
40ITGA2B, ITGB3, MMP2
MMP-2 regulates human platelet activation by interacting with integrin alphaIIbbeta3.
Choi WS, Jeon OH, Kim HH, Kim DS.
J Thromb Haemost 6(3):517-23. Epub 2007 Dec 12. 2008
41HTR5A, SLC6A4, ITGB3
Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the determination of platelet serotonin levels.
Coutinho AM, Sousa I, Martins M, Correia C, Morgadinho T, Bento C, Marques C, Ataide A, Miguel TS, Moore JH, Oliveira G, Vicente AM.
Hum Genet 121(2):243-56. Epub 2007 Jan 3. 2007
42ITGB3, MARCKSL1
The regulation of MacMARCKS expression by integrin beta3.
van den Bout I, Truong HH, Huveneers S, Kuikman I, Danen EH, Sonnenberg A.
Exp Cell Res 313(6):1260-9. Epub 2007 Jan 12. 2007
43ITGA2B, ITGB3
Platelet integrin alpha(IIb)beta(3): activation mechanisms.
Ma YQ, Qin J, Plow EF.
J Thromb Haemost 5(7):1345-52. Review. 2007
44NFATC1, ITGB3
NFATc1 regulation of the human beta3 integrin promoter in osteoclast differentiation.
Crotti TN, Flannery M, Walsh NC, Fleming JD, Goldring SR, McHugh KP.
Gene 372:92-102. Epub 2006 Mar 2. 2006
45ITGB3
Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility.
Weiss LA, Kosova G, Delahanty RJ, Jiang L, Cook EH, Ober C, Sutcliffe JS.
Eur J Hum Genet 14(8):923-31. Epub 2006 May 17. 2006
46ITGA1, ITGB3
Expression of alpha 1 and beta 3 integrins subunits in the endometrium of patients with tubal phimosis or hydrosalpinx.
Savaris RF, Pedrini JL, Flores R, Fabris G, Zettler CG.
Fertil Steril 85(1):188-92. 2006
47ITGA2, ITGB3
Integrin alpha-2 and beta-3 gene polymorphisms and breast cancer risk.
Langsenlehner U, Renner W, Yazdani-Biuki B, Eder T, Wascher TC, Paulweber B, Clar H, Hofmann G, Samonigg H, Krippl P.
Breast Cancer Res Treat 97(1):67-72. 2006
48ITGA3, ITGB1, ITGB3, ITGAV
Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.
Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R.
J Biol Chem 281(30):20932-9. Epub 2006 May 26. 2006
49MCAM, CDH2, ITGB3
The role of N-cadherin, MCAM and beta3 integrin in melanoma progression, proliferation, migration and invasion.
Watson-Hurst K, Becker D.
Cancer Biol Ther 5(10):1375-82. Epub 2006 Oct 26. 2006
50ITGB3
Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample.
Weiss LA, Abney M, Parry R, Scanu AM, Cook EH Jr, Ober C.
Hum Genet 117(1):81-7. Epub 2005 Apr 15. 2005
51ADAM12,ITGB1,ITGB3
ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
Thodeti CK, Frohlich C, Nielsen CK, Takada Y, Fassler R, Albrechtsen R, Wewer UM.
FEBS Lett 579(25):5589-95. Epub 2005 Sep 28. 2005
52ITGB3, EMP2
Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium.
Wadehra M, Forbes A, Pushkarna N, Goodglick L, Gordon LK, Williams CJ, Braun J.
Dev Biol 287(2):336-45. Epub 2005 Oct 10. 2005
53ITGB3
Genetic variation of the platelet- surface integrin GPIIb-IIIa (PIA1/A2-SNP) shows a high association with Type 2 diabetes mellitus.
Tschoepe D, Menart B, Ferber P, Altmann C, Haude M, Haastert B, Roesen P.
Diabetologia 46(7):984-9. Epub 2003 Jun 21. 2003
54ITGB3
Thrombophilic polymorphisms in pre-eclampsia : altered frequency of the functional 98C>T polymorphism of glycoprotein IIIa.
O'Shaughnessy KM, Fu B, Downing S, Morris NH.
J Med Genet 38 : 775-777. 2001
55GT2,GT3,ITGA2B,ITGB3
Molecular genetic analysis of a compound heterozygote for the glycoprotein (GP) IIb gene associated with Glanzmann's thrombasthenia: disruption of the 674-687 disulfide bridge in GPIIb prevents surface exposure of GPIIb-IIIa complexes.
Gonzalez-Manchon C, et al.
Blood 93(3):866-75. 1999
56ITGB3
An adenine trimer precedes a C/G polymorphism in the 3'-amplimer region of the human platelet glycoprotein IIIa intron 6 CT repeat.
Denomme GA.
Hum Hered 48(2):115-8. 1998
57ITGB3, SERPINE1
Array-based multiplex analysis of candidate genes reveals two independent and additive genetic risk factors for myocardial infarction in the Finnish population.
Pastinen T, et al.
Hum Mol Genet 7 : 1453-1462. 1998
58ITGB3
Human integrin beta3 gene rxpression : evidence for a megakaryocytic cell-specific cis-acting element.
Jin Y, et al.
Blood 92 : 2777-2790. 1998
59GT3,ITGB3
Three novel integrin beta3 subunit missense mutations (H280P, C560F, and G579S) in thrombasthenia, including one (H280P) prevalent in Japanese patients.
Ambo H, Kamata T, Handa M, Taki M, Kuwajima M, Kawai Y, Oda A, Murata M, Takada Y, Watanabe K, Ikeda Y.
Biochem Biophys Res Commun 251 : 763-768. 1998
60GT3,ITGB3
A Glanzmann thrombasthenia-like phenotype caused by a defect in inside-out signaling through the integrin alpha(IIb)beta3.
Tomiyama Y, Shiraga M, Kinoshita S, Ambo H, Kurata Y, Matsuzawa Y, Kunicki TJ.
Thromb Haemost 80 : 735-742. 1998
61GT2,GT3,ITGA2B,ITGB3
Truncation of glycoprotein (GP) IIIa (616-762) prevents complex formation with GPIIb : novel mutation in exon 11 of GPIIIa associated with thrombasthenia.
Ferrer M, et al.
Blood 92 : 4712-4720. 1998
62ITGB3
PIA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis.
Ridker PM, et al.
Lancet 349 : 385-388. 1997
63GT3,ITGB3
Glanzmann thrombasthenia caused by an 11.2-kb deletion in the glycoprotein IIIa (beta3) is a second mutation in Iraqi Jews that stemmed from a distinct founder.
Rosenberg N, Yatuv R, Orion Y, Zivelin A, Dardik R, Peretz H, Seligsohn U.
Blood 89(10):3654-62. 1997
64GT3,ITGB3
A three amino acid deletion in glycoprotein IIIa is responsible for type I Glanzmann's thrombasthenia: importance of residues Ile325Pro326Gly327 for beta3 integrin subunit association.
Morel-Kopp MC, Kaplan C, Proulle V, Jallu V, Melchior C, Peyruchaud O, Aurousseau MH, Kieffer N.
Blood 90(2):669-77. 1997
65GT3,ITGB3
Glanzmann thrombasthenia. Cooperation between sequence variants in cis during splice site selection.
Jin Y, et al.
J Clin Invest 98 : 1745-1754. 1996
66ITGB3
An additional HpaII polymorphism in exon 2 of the human platelet membrane glycoprotein IIIa gene.
Perichon B, et al.
Hum Genet 93 : 353-354. 1994
67ITGB3
A point mutation leads to an unpaired cysteine residue and a molecular weight polymorphism of a functional platelet beta3 integrin subunit.
Santoso S, et al.
J Biol Chem 269 : 8439-8444. 1994
68ITGB3
A point mutation in the integrin beta3 cytoplasmic domain (S752-P) impairs bidirectional signaling through alphaIIbbeta3 (platelet glycoprotein IIb-IIIa).
Chen YP, et al.
Blood 84 : 1857-1865. 1994
69ITGB3
A new alternative transcript encodes a 60 kDa truncated form of integrin beta 3.
Djaffar I, Chen YP, Creminon C, Maclouf J, Cieutat AM, Gayet O, Rosa JP.
Biochem J 300 ( Pt 1):69-74. 1994
70GT3,ITGB3
A second case of variant of Glanzmann's thrombasthenia due to substitution of platelet GPIIIa (integrin beta3) Arg214 by Trp.
Djaffar I, et al.
Hum Mol Genet 2 : 2179-2180. 1993
71GT3,ITGB3
A large alteration in the human platelet glycoprotein IIIa (integrin beta3) gene associated with Glanzmann's thrombasthenia.
Djaffar I, et al.
Hum Mol Genet 2 : 2183-2185. 1993
72GT3,ITGB3
Homologous recombination among three intragene Alu sequences causes an inversion-deletion resulting in the hereditary bleeding disorder Glanzmann thrombasthenia.
Li L, et al.
Am J Hum Genet 53 : 140-149. 1993
73ITGB3
Single point mutation in human glycoprotein IIIa is associated with a new platelet-specific alloantigen (Mo) involved in neonatal alloimmune thrombocytopenia.
Kuijpers RW, et al.
Blood 81 : 70-76. 1993
74ITGB3
Microsatellite polymorphism in the human platelet glycoprotein llla gene (GP3A) on chromosome 17.
Stoffel M, et al.
Nucleic Acids Res 20 : 1172. 1992
75GT3,ITGB3
A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg-214Trp mutation.
Lanza F, et al.
J Clin Invest 89 : 1995-2004. 1992
76ITGB3
Homologous recombination between 3 intragene Alu sequences causes a deletion-inversion resulting in the hereditary bleeding disorder, Glanzmann thrombasthenia.
Bray PF, et al.
Am J Hum Genet 51 : A209. 1992
77ITGB3
An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pen-a/Pen-b alloantigen system.
Wang R, et al.
J Clin Invest 90 : 2038-2043. 1992
78GT3,ITGB3
Ser-752--Pro mutation in the cytoplasmic domain of integrin beta3 subunit and defective activation of platelet integrin alphaIIb-beta3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia.
Chen YP, et al.
Proc Natl Acad Sci U S A 89 : 10169-10173. 1992
79ITGA2B, ITGB3, GT2, GT3
The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel.
Newman PJ, et al.
Proc Natl Acad Sci U S A 88 : 3160-3164. 1991
80GT3,ITGB3
Identification of an abnormal gene for the GPIIIa subunit of the platelet fibrinogen receptor resulting in Glanzmann's thrombasthenia.
Bray PF, et al.
Blood 75 : 881-888. 1990
81ITGB3
Characterization of the human platelet glycoprotein IIIa gene. Comparison with the fibronectin receptor beta-subunit gene.
Lanza F, Kieffer N, Phillips DR, Fitzgerald LA.
J Biol Chem 265(30):18098-103. 1990
82ITGB3
Assignment of GP3A gene to chromosome 17 (somatic cell hybrid analysis), region q21.1-q21.3 (in situ hybridization).
Nguyen Van Cong, et al.
(HGM10) Cytogenet Cell Genet 51 : 1096-1097. 1989
83GT2,GT3,ITGA2B,ITGB3
Glanzmann's thrombasthenia.
Caen JP.
Baillire Clin Haematol 2 : 609-625. 1989
84ITGB3
An alternative cytoplasmic domain of the integrin beta 3 subunit.
van Kuppevelt TH, Languino LR, Gailit JO, Suzuki S, Ruoslahti E.
Proc Natl Acad Sci U S A 86(14):5415-8. 1989
85ITGA2B, ITGB3
Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa.
Bray PF, Barsh G, Rosa JP, Luo XY, Magenis E, Shuman MA.
Proc Natl Acad Sci U S A 85 : 8683-8687. 1988
86ITGA2B, ITGB3, ITGAV, ITGA5, ITGB1
Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa.
Sosnoski DM, Emanuel BS, Hawkins AL, van Tuinen P, Ledbetter DH, Nussbaum RL, Kaos FT, Schwartz E, Phillips D, Bennett JS, et al.
J Clin Invest 81(6):1993-8. 1988
87ITGB3
A Taq 1 polymorphism for the human platelet glycoprotein IIIa gene (GP3A).
Burk C, et al.
Nucleic Acids Res 16 : 7216. 1988
88ITGB3
Cloning of glycoprotein IIIa cDNA from human erythroleukemia cells and localization of the gene to chromosome 17.
Rosa JP, et al.
Blood 72 : 593-600. 1988