1 | ITGA6, NLGN1
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| Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.
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| Samarelli AV, Riccitelli E, Bizzozero L, Silveira TN, Seano G, Pergolizzi M, Vitagliano G, Cascone I, Carpentier G, Bottos A, Primo L, Bussolino F, Arese M.
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| J Biol Chem. Jul 11;289(28):19466-76. doi: 10.1074/jbc.M113.530972. Epub 2014 May 23. Erratum in: J Biol Chem. 2014 Sep 12;289(37):25475. 2014
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2 | ITGA6
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| P-Cadherin Is Coexpressed with CD44 and CD49f and Mediates Stem Cell Properties in Basal-like Breast Cancer.
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| Vieira AF, Ricardo S, Ablett MP, Dionísio MR, Mendes N, Albergaria A, Farnie G, Gerhard R, Cameselle-Teijeiro JF, Seruca R, Schmitt F, Clarke RB, Paredes J.
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| Stem Cells 30(5):854-64. doi: 10.1002/stem.1075.
2012
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3 | ITGA6
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| CD49f Enhances Multipotency and Maintains Stemness Through the Direct Regulation of OCT4 and SOX2.
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| Yu KR, Yang SR, Jung JW, Kim H, Ko K, Han DW, Park SB, Choi SW, Kang SK, Schöler H, Kang KS.
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| Stem Cells 30(5):876-87. doi: 10.1002/stem.1052.
2012
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4 | ITGA6
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| Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment.
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| Notta F, Doulatov S, Laurenti E, Poeppl A, Jurisica I, Dick JE.
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| Science 333(6039):218-21.
2011
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5 | ITGA6
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| alpha6-integrin subunit plays a major role in the proangiogenic properties of endothelial progenitor cells.
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| Bouvard C, Gafsou B, Dizier B, Galy-Fauroux I, Lokajczyk A, Boisson-Vidal C, Fischer AM, Helley D.
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| Arterioscler Thromb Vasc Biol 30(8):1569-75. Epub 2010 May 27.
2010
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6 | ITGA6
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| Integrin alpha 6 regulates glioblastoma stem cells.
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| Lathia JD, Gallagher J, Heddleston JM, Wang J, Eyler CE, Macswords J, Wu Q, Vasanji A, McLendon RE, Hjelmeland AB, Rich JN.
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| Cell Stem Cell 6(5):421-32.
2010
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7 | ITGA6, JUN, TAF4B
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| TAF4b and Jun/activating protein-1 collaborate to regulate the expression of integrin alpha6 and cancer cell migration properties.
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| Kalogeropoulou M, Voulgari A, Kostourou V, Sandaltzopoulos R, Dikstein R, Davidson I, Tora L, Pintzas A.
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| Mol Cancer Res 8(4):554-68. doi: 10.1158/1541-7786.MCR-09-0159. Epub 2010 Mar 30.
2010
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8 | ITGA6
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| Extracellular engagement of alpha6 integrin inhibited urokinase-type plasminogen activator-mediated cleavage and delayed human prostate bone metastasis.
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| Ports MO, Nagle RB, Pond GD, Cress AE.
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| Cancer Res 69(12):5007-14. Epub 2009 Jun 2.
2009
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9 | ITGA6
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| Overexpression of CD49f in precursor B-cell acute lymphoblastic leukemia: potential usefulness in minimal residual disease detection.
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| DiGiuseppe JA, Fuller SG, Borowitz MJ.
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| Cytometry B Clin Cytom 76(2):150-5.
2009
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10 | ITGA6
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| Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line.
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| Cariati M, Naderi A, Brown JP, Smalley MJ, Pinder SE, Caldas C, Purushotham AD.
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| Int J Cancer 122(2):298-304.
2008
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11 | ITGA6
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| Laminin reduces expression of the human alpha6 integrin subunit gene by altering the level of the transcription factors Sp1 and Sp3.
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| Gaudreault M, Vigneault F, Leclerc S, Guérin SL.
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| Invest Ophthalmol Vis Sci 48(8):3490-505.
2007
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12 | ITGA4, ITGA6
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| Distinct roles of integrins alpha6 and alpha4 in homing of fetal liver hematopoietic stem and progenitor cells.
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| Qian H, Georges-Labouesse E, Nyström A, Domogatskaya A, Tryggvason K, Jacobsen SE, Ekblom M.
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| Blood 110(7):2399-407. Epub 2007 Jun 22.
2007
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13 | ITGA6
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| Integrin alpha6 cleavage: a novel modification to modulate cell migration.
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| Pawar SC, Demetriou MC, Nagle RB, Bowden GT, Cress AE.
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| Exp Cell Res 313(6):1080-9. Epub 2007 Jan 17.
2007
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14 | COL17A1, EBJ1A, EBJ1B, EBJ1C, EBJ2A, EBJ2B, EBJ2C, EBJ2D, EBJ2E, EBJPAA, EBS1, EBSMD, ITGA6, ITGB4, LAMA3, LAMB3, LAMC2, PLEC
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| Epidermolysis bullosa. I. Molecular genetics of the junctional and hemidesmosomal variants.
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| Varki R, Sadowski S, Pfendner E, Uitto J.
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| J Med Genet 43(8):641-52. Epub 2006 Feb 10. 2006
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15 | LAMA1, LAMA2, LAMA3, LAMA4, LAMA5, LAMB1, LAMB2, LAMB3, LAMC1, LAMC2, LAMC3, ITGA3, ITGA6, ITGB1, ITGB4
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| Retinal pigment epithelial cells synthesize laminins, including laminin 5, and adhere to them through alpha3- and alpha6-containing integrins.
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| Aisenbrey S, Zhang M, Bacher D, Yee J, Brunken WJ, Hunter DD.
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| Invest Ophthalmol Vis Sci 47(12):5537-44. 2006
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16 | LAMC2, LAMA5, ITGB4, ITGA6
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| Laminin 5 regulates polycystic kidney cell proliferation and cyst formation.
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| Joly D, Berissi S, Bertrand A, Strehl L, Patey N, Knebelmann B.
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| J Biol Chem 281(39):29181-9. Epub 2006 Jul 26. 2006
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17 | LAMA5, ITGA6
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| Keratinocyte-secreted laminin 5 can function as a transient receptor for human papillomaviruses by binding virions and transferring them to adjacent cells.
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| Culp TD, Budgeon LR, Marinkovich MP, Meneguzzi G, Christensen ND.
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| J Virol 80(18):8940-50. 2006
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18 | ITGA6, ITGB4, PTHLH
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| PTH-related protein upregulates integrin alpha6beta4 expression and activates Akt in breast cancer cells.
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| Shen X, Falzon M.
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| Exp Cell Res 312(19):3822-34. Epub 2006 Aug 17. 2006
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19 | LAMA1, ITGA6
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| Selective down-regulation of the alpha6-integrin subunit in melanocytes by UVB light.
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| Krengel S, Stark I, Geuchen C, Knoppe B, Scheel G, Schlenke P, Gebert A, Wunsch L, Brinckmann J, Tronnier M.
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| Exp Dermatol 14(6):411-9 2005
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20 | ITGA6, CYR61
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| Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61).
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| Leu SJ, Liu Y, Chen N, Chen CC, Lam SC, Lau LF.
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| J Biol Chem 278(36):33801-8. Epub 2003 Jun 24. 2003
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21 | EBJPAA, ITGA6
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| Homozygous alpha6 integrin mutation in junctional epidermolysis bullosa with congenital duodenal atresia.
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| Pulkkinen L, Kimonis VE, Xu Y, Spanou EN, McLean WH, Uitto J.
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| Hum Mol Genet 6(5):669-74. 1997
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22 | EBJPAA, ITGA6
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| A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresia.
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| Ruzzi L, Gagnoux-Palacios L, Pinola M, Belli S, Meneguzzi G, D'Alessio M, Zambruno G.
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| J Clin Invest 99(12):2826-31. 1997
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23 | ITGA6
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| Identification of the human alpha6 integrin gene promoter.
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| Lin CS, Chen Y, Huynh T, Kramer R.
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| DNA Cell Biol 16(8):929-37. 1997
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24 | ITGA6, ITGB4
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| Molecular cloning of the human alpha 6 integrin subunit. Alternative splicing of alpha 6 mRNA and chromosomal localization of the alpha 6 and beta 4 genes.
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| Hogervorst F, Kuikman I, van Kessel AG, Sonnenberg A.
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| Eur J Biochem 199(2):425-33. 1991
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25 | ITGA6, ITGB4
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| Localization of the human alpha-6 and beta-4 integrin genes on chromosome 2 and 17, respectively.
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| Hogervorst F, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 1869. 1991
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26 | ITGA6, ITGB4
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| A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.
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| Kajiji S, Tamura RN, Quaranta V.
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| EMBO J 8(3):673-80. 1989
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27 | ITGA6
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| 46.
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| The role of alpha 6 integrin in prostate cancer migration and bone pain in a novel xenograft model.
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| King TE, Pawar SC, Majuta L, Sroka IC, Wynn D, Demetriou MC, Nagle RB, Porreca F, Cress AE ing TE, Pawar SC, Majuta L, Sroka IC, Wynn D, Demetriou MC, Nagle RB, Porreca F, Cress AE.
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