1 | IRX2, RUVBL1
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| IRX2 regulates endometrial carcinoma oncogenesis by transcriptional repressing RUVBL1.
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| Xu Q, Zhou W, Zhou Y, Zhang X, Jiang R, Ai Z, Chen J, Ma L.
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| Exp Cell Res Jan 1;434(1):113866. doi: 10.1016/j.yexcr.2023.113866. Epub 2023 Nov 30. 2024
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2 | IRX2
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| Expression Profile and Prognostic Values of IRX Family Members in Lung Adenocarcinoma.
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| Zhang J, Zhou Y, Li X, Wang S, Zhang P, Li D, Zhou Y.
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| Curr Med Chem. Sep 6. doi: 10.2174/0109298673320965240829065919. Epub ahead of print. 2024
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3 | EGR1, IRX2
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| IRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice.
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| Ma ZG, Yuan YP, Fan D, Zhang X, Teng T, Song P, Kong CY, Hu C, Wei WY, Tang QZ.
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| Nat Commun. Aug 16;14(1):4967. doi: 10.1038/s41467-023-40639-6 2023
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4 | IRX2, KDM4A
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| IRX2 activated by jumonji domain-containing protein 2A is crucial for cardiac hypertrophy and dysfunction in response to the hypertrophic stimuli.
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| Wang K, Zhou M, Zhang Y, Du Y, Li P, Guan C, Huang Z.
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| Int J Cardiol. Jan 15;371:332-344. doi: 10.1016/j.ijcard.2022.09.070. Epub 2022 Sep 29. 2023
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5 | IRX2
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| Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease.
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| Sim H, Lee JE, Yoo HM, Cho S, Lee H, Baek A, Kim J, Seo H, Kweon MN, Kim HG, Jeon YJ, Son MY, Kim J.
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| nt J Mol Sci. May 14;21(10):3455. doi: 10.3390/ijms21103455. 2020
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6 | IRX2
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| Up-regulation of the IRX2 gene predicts poor prognosis in nasopharyngeal carcinoma.
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| Si J, Si Y, Zhang B, Lan G, Wei J, Huang B, Deng Z, Xiong W, Zhang Q.
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| Int J Clin Exp Pathol. Aug 1;11(8):4073-4082. 2018
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7 | IRX2, TERT
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| Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.
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| Karlsson J, Lilljebjörn H, Holmquist Mengelbier L, Valind A, Rissler M, Øra I, Fioretos T, Gisselsson D
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| Cancer Lett. Feb 28;357(2):498-501. doi: 10.1016/j.canlet.2014.11.057. Epub 2014 Dec 3. 2015
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8 | IRX2
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| IRX-2, a novel immunotherapeutic, enhances functions of human dendritic cells.
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| Schilling B, Harasymczuk M, Schuler P, Egan J, Ferrone S, Whiteside TL.
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| PLoS One 8(2):e47234. doi: 10.1371/journal.pone.0047234. Epub 2013 Feb 7 2013
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9 | BDKRB2, FGF7, HIST2H2BE, IRX1, IRX2, IRX3
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| Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma.
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| Guo X, Liu W, Pan Y, Ni P, Ji J, Guo L, Zhang J, Wu J, Jiang J, Chen X, Cai Q, Li J, Zhang J, Gu Q, Liu B, Zhu Z, Yu Y.
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| Oncogene 29(27):3908-20. Epub 2010 May 3. 2010
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10 | TRIO, NKD2, IRX2
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| Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas.
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| Adamowicz M, Radlwimmer B, Rieker RJ, Mertens D, Schwarzbach M, Schraml P, Benner A, Lichter P, Mechtersheimer G, Joos S.
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| Genes Chromosomes Cancer 45(9):829-38. 2006
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11 | IRX1, IRX2, IRX3, IRX4, IRX5, IRX6
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| Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes.
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| Ogura K, Matsumoto K, Kuroiwa A, Isobe T, Otoguro T, Jurecic V, Baldini A, Matsuda Y, Ogura T.
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| Cytogenet Cell Genet 92(3-4):320-5. 2001
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