Citations for
1DDX58, IFIH1, IFNB1, IRF7
Deficient pulmonary IFN-β expression in COPD patients.
García-Valero J, Olloquequi J, Montes JF, Rodríguez E, Martín-Satué M, Texidó L, Ferrer Sancho J.
PLoS One 14(6):e0217803. doi: 10.1371/journal.pone.0217803. eCollection 2019. Erratum in: PLoS One. 2019 Jul 1;14(7):e0219349. 2019
2IRF3, IRF5, IRF7
DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: implications for dimer-specific gene regulation.
Andrilenas KK, Ramlall V, Kurland J, Leung B, Harbaugh AG, Siggers T.
Nucleic Acids Res ucleic Acids Res. 2018 Jan 18. doi: 10.1093/nar/gky002. [Epub ahead of print] 2018
3IRF7, S100A9
IRF7 regulates the development of granulocytic myeloid-derived suppressor cells through S100A9 transrepression in cancer.
Yang Q, Li X, Chen H, Cao Y, Xiao Q, He Y, Wei J, Zhou J.
Oncogene 36(21):2969-2980. doi: 10.1038/onc.2016.448. Epub 2017 Jan 16. 2017
4CRADD, IKBKE, IRF7
RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production.
Maney SK, Xu HC, Huang J, Pandyra AA, Ehlting C, Aguilar-Valenzuela R, Pozdeev VI, McIlwain DR, Zimmermann A, Bode JG, Hengel H, Kirschning CJ, Kim IR, Hiscott J, Brenner D, Häussinger D, Ohashi PS, Mak TW, Lang KS, Lang PA.
Cell Physiol Biochem 39(4):1271-80. doi: 10.1159/000447832. 2016
5IRF7, NFATC3
NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells.
Bao M, Wang Y, Liu Y, Shi P, Lu H, Sha W, Weng L, Hanabuchi S, Qin J, Plumas J, Chaperot L, Zhang Z, Liu YJ.
J Exp Med 213(11):2383-2398. Epub 2016 Oct 3. 2016
6IRF7, USP25
The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene.
Ren Y, Zhao Y, Lin D, Xu X, Zhu Q, Yao J, Shu HB, Zhong B.
J Biol Chem 291(25):13206-15. doi: 10.1074/jbc.M116.718080. Epub 2016 Apr 27. 2016
7BCL6, IRF7
Bcl6 Sets a Threshold for Antiviral Signaling by Restraining IRF7 Transcriptional Program.
Xu F, Kang Y, Zhuang N, Lu Z, Zhang H, Xu D, Ding Y, Yin H, Shi L.
Sci Rep 6:18778. doi: 10.1038/srep18778. Erratum in: Sci Rep. 2017 Sep 20;7:46904. 2016
8IMD39, IRF7
Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency.
Ciancanelli MJ, Huang SX, Luthra P, Garner H, Itan Y, Volpi S, Lafaille FG, Trouillet C, Schmolke M, Albrecht RA, Israelsson E, Lim HK, Casadio M, Hermesh T, Lorenzo L, Leung LW, Pedergnana V, Boisson B, Okada S, Picard C, Ringuier B, Troussier F, Chaussabel D, Abel L, Pellier I, Notarangelo LD, García-Sastre A, Basler CF, Geissmann F, Zhang SY, Snoeck HW, Casanova JL.
Science 348(6233):448-53. doi: 10.1126/science.aaa1578. Epub 2015 Mar 26. 2015
9IRF7, TLR7, TLR9, TRIM35
TRIM35 negatively regulates TLR7- and TLR9-mediated type I interferon production by targeting IRF7.
Wang Y, Yan S, Yang B, Wang Y, Zhou H, Lian Q, Sun B.
FEBS Lett 589(12):1322-30. doi: 10.1016/j.febslet.2015.04.019. Epub 2015 Apr 20. 2015
10AIP, IRF7
Aryl Hydrocarbon Receptor Interacting Protein Targets IRF7 to Suppress Antiviral Signaling and the Induction of Type I Interferon.
Zhou Q, Lavorgna A, Bowman M, Hiscott J, Harhaj EW.
J Biol Chem 290(23):14729-39. doi: 10.1074/jbc.M114.633065. Epub 2015 Apr 24. 2015
11AGO2, IRF7
IRF7 promotes glioma cell invasion by inhibiting AGO2 expression.
Kim JK, Jin X, Ham SW, Lee SY, Seo S, Kim SC, Kim SH, Kim H.
Tumour Biol 36(7):5561-9. doi: 10.1007/s13277-015-3226-4. Epub 2015 Feb 14. 2015
12IRF7, NMI
A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.
Brozzi F, Gerlo S, Grieco FA, Nardelli TR, Lievens S, Gysemans C, Marselli L, Marchetti P, Mathieu C, Tavernier J, Eizirik DL.
J Biol Chem 289(30):20677-93. 2014
13IRF7
Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation.
Huang L, Zhang SM, Zhang P, Zhang XJ, Zhu LH, Chen K, Gao L, Zhang Y, Kong XJ, Tian S, Zhang XD, Li H.
J Am Heart Assoc 3(5):e001309. doi: 10.1161/JAHA.114.001309. 2014
14IRF7, PELI3
Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons.
Siednienko J, Jackson R, Mellett M, Delagic N, Yang S, Wang B, Tang LS, Callanan JJ, Mahon BP, Moynagh PN.
Nat Immunol 13(11):1055-62. doi: 10.1038/ni.2429. Epub 2012 Oct 7. 2012
15FOXO3, IRF7
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.
Litvak V, Ratushny AV, Lampano AE, Schmitz F, Huang AC, Raman A, Rust AG, Bergthaler A, Aitchison JD, Aderem A.
Nature 490(7420):421-5. doi: 10.1038/nature11428. Epub 2012 Sep 16. 2012
16GBP4, IRF7
Guanylate binding protein 4 negatively regulates virus-induced type I IFN and antiviral response by targeting IFN regulatory factor 7.
Hu Y, Wang J, Yang B, Zheng N, Qin M, Ji Y, Lin G, Tian L, Wu X, Wu L, Sun B.
J Immunol 187(12):6456-62. doi: 10.4049/jimmunol.1003691. Epub 2011 Nov 16. 2011
17AP3B1, IRF7, TLR9, TRAF3
Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3.
Sasai M, Linehan MM, Iwasaki A.
Science 329(5998):1530-4. 2010
18IRF7, TNFAIP3
The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7.
Ning S, Pagano JS.
J Virol 84(12):6130-8. Epub 2010 Apr 14.PMID: 20392859 2010
19IRF7
Dual functions of interferon regulatory factors 7C in Epstein-Barr virus-mediated transformation of human B lymphocytes.
Zhao Y, Xu D, Jiang Y, Zhang L.
PLoS One 5(3):e9459.PMID: 20209099 2010
20IRF7
Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7.
Génin P, Lin R, Hiscott J, Civas A.
Mol Cell Biol 29(12):3435-50. Epub 2009 Apr 6.PMID: 19349300 2009
21IRF7
The IFN regulatory factor 7-dependent type I IFN response is not essential for early resistance against murine cytomegalovirus infection.
Steinberg C, Eisenächer K, Gross O, Reindl W, Schmitz F, Ruland J, Krug A.
Eur J Immunol 39(4):1007-18.PMID: 19283778 2009
22IRF7, TAF6
TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1.
Ning S, Campos AD, Darnay BG, Bentz GL, Pagano JS.
Mol Cell Biol 28(20):6536-46. Epub 2008 Aug 18.PMID: 18710948 2008
23IRF5, IRF7
Interferon regulatory factors IRF5 and IRF7 inhibit growth and induce senescence in immortal Li-Fraumeni fibroblasts.
Li Q, Tang L, Roberts PC, Kraniak JM, Fridman AL, Kulaeva OI, Tehrani OS, Tainsky MA.
Mol Cancer Res 6(5):770-84.PMID: 18505922 2008
24TLR7, TLR9, IRF7, MYD88, CHUK
IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9.
Hoshino K, Sugiyama T, Matsumoto M, Tanaka T, Saito M, Hemmi H, Ohara O, Akira S, Kaisho T.
Nature 440(7086):949-53. 2006
25IRF7
IRF-7 is the master regulator of type-I interferon-dependent immune responses.
Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T.
Nature 434(7034):772-7. Epub 2005 Mar 30. 2005
26IRF7, IRF3
Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling.
Ning S, Huye LE, Pagano JS.
J Biol Chem 280(13):12262-70. Epub 2005 Jan 21. 2005
27IRF7
The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation.
Yu Y, Wang SE, Hayward GS.
Immunity 22(1):59-70. 2005
28IRF7, TRAF6, MYD88
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6.
Kawai T, Sato S, Ishii KJ, Coban C, Hemmi H, Yamamoto M, Terai K, Matsuda M, Inoue J, Uematsu S, Takeuchi O, Akira S.
Nat Immunol 5(10):1061-8. Epub 2004 Sep 7. 2004
29IRF7
Stimulation of IRF-7 gene expression by tumor necrosis factor alpha: requirement for NFkappa B transcription factor and gene accessibility.
Lu R, Moore PA, Pitha PM.
J Biol Chem 277(19):16592-8. Epub 2002 Feb 27. 2002
30IRF7, MUPCDH, DEAF1
Characterization of a 500-kb contig spanning the region between c-Ha-Ras and MUC2 on chromosome 11p15.5.
Paris MJ, Williams BRG.
Genomics 69 : 196-202. 2000
31IRF7
Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon snd silencing by hypermethylation.
Lu R, Au WC, Yeow WS, Hageman N, Pitha PM.
J Biol Chem 275(41):31805-12. 2000
32IRF7
Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes.
Au WC, et al.
J Biol Chem 273(44):29210-7. 1998
33IRF7
IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency.
Zhang L, et al.
Mol Cell Biol 17(10):5748-57. 1997