| 1 | FOXC1, FOXF2, GMDS, IRF4, RG6
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| Molecular characterization of a novel ring 6 chromosome using next generation sequencing.
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| Zhang R, Chen X, Li P, Lu X, Liu Y, Li Y, Zhang L, Xu M, Cram DS.
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| Mol Cytogenet. Apr 21;9:33. doi: 10.1186/s13039-016-0245-9. eCollection 2016 2016
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| 2 | ASIP, BNC2, IRF4, MC1R, RALY
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| A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots.
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| Jacobs LC, Hamer MA, Gunn DA, Deelen J, Lall JS, van Heemst D, Uh HW, Hofman A, Uitterlinden AG, Griffiths CE, Beekman M, Slagboom PE, Kayser M, Liu F, Nijsten T.
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| J Invest Dermatol 135(7):1735-42. doi: 10.1038/jid.2015.62. Epub 2015 Feb 23.
2015
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| 3 | IRF4, SMAD2, SMAD3
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| Smad2/3 and IRF4 play a cooperative role in IL-9-producing T cell induction.
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| Tamiya T, Ichiyama K, Kotani H, Fukaya T, Sekiya T, Shichita T, Honma K, Yui K, Matsuyama T, Nakao T, Fukuyama S, Inoue H, Nomura M, Yoshimura A.
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| J Immunol 191(5):2360-71. doi: 10.4049/jimmunol.1301276. Epub 2013 Aug 2.
2013
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| 4 | EOMES, IRF4, ITK
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| TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation.
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| Nayar R, Enos M, Prince A, Shin H, Hemmers S, Jiang JK, Klein U, Thomas CJ, Berg LJ.
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| Proc Natl Acad Sci U S A 109(41):E2794-802. doi: 10.1073/pnas.1205742109. Epub 2012 Sep 24.
2012
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| 5 | IRF4
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| IRF-4 suppresses BCR/ABL transformation of myeloid cells in a DNA binding-independent manner.
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| Jo SH, Ren R.
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| J Biol Chem 287(3):1770-8. doi: 10.1074/jbc.M111.289728. Epub 2011 Nov 22.
2012
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| 6 | BATF, IRF4
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| BATF-JUN is critical for IRF4-mediated transcription in T cells.
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| Li P, Spolski R, Liao W, Wang L, Murphy TL, Murphy KM, Leonard WJ.
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| Nature 490(7421):543-6. doi: 10.1038/nature11530. Epub 2012 Sep 19.
2012
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| 7 | IRF4, PRDM1
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| The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells.
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| Cretney E, Xin A, Shi W, Minnich M, Masson F, Miasari M, Belz GT, Smyth GK, Busslinger M, Nutt SL, Kallies A.
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| Nat Immunol 12(4):304-11. Epub 2011 Mar 6.
2011
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| 8 | IL10, IRF4
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| IRF4 regulates IL-10 gene expression in CD4(+) T cells through differential nuclear translocation.
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| Lee CG, Hwang W, Maeng KE, Kwon HK, So JS, Sahoo A, Lee SH, Park ZY, Im SH.
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| Cell Immunol 268(2):97-104. Epub 2011 Mar 4.
2011
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| 9 | IRF4
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| IRF4 mutations in chronic lymphocytic leukemia.
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| Havelange V, Pekarsky Y, Nakamura T, Palamarchuk A, Alder H, Rassenti L, Kipps T, Croce CM.
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| Blood 118(10):2827-9. doi: 10.1182/blood-2011-04-350579. Epub 2011 Jul 25.
2011
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| 10 | IL2, IL4, IRF4, REL
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| Interferon regulatory factor-4 activates IL-2 and IL-4 promoters in cooperation with c-Rel.
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| Shindo H, Yasui K, Yamamoto K, Honma K, Yui K, Kohno T, Ma Y, Chua KJ, Kubo Y, Aihara H, Ito T, Nagayasu T, Matsuyama T, Hayashi H.
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| Cytokine 56(3):564-72. doi: 10.1016/j.cyto.2011.08.014. Epub 2011 Sep 3.
2011
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| 11 | IRF4, IRF5, IRF8, PRDM1
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| Critical role of IRF-5 in regulation of B-cell differentiation.
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| Lien C, Fang CM, Huso D, Livak F, Lu R, Pitha PM.
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| Proc Natl Acad Sci U S A 107(10):4664-8. Epub 2010 Feb 22. 2010
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| 12 | IRF4
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| Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells.
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| Staudt V, Bothur E, Klein M, Lingnau K, Reuter S, Grebe N, Gerlitzki B, Hoffmann M, Ulges A, Taube C, Dehzad N, Becker M, Stassen M, Steinborn A, Lohoff M, Schild H, Schmitt E, Bopp T.
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| Immunity mmunity. 2010 Jul 29. [Epub ahead of print]PMID: 20674401 2010
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| 13 | IRF4
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| IRF4 variants have age-specific effects on nevus count and predispose to melanoma.
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| Duffy DL, Iles MM, Glass D, Zhu G, Barrett JH, Höiom V, Zhao ZZ, Sturm RA, Soranzo N, Hammond C, Kvaskoff M, Whiteman DC, Mangino M, Hansson J, Newton-Bishop JA; GenoMEL, Bataille V, Hayward NK, Martin NG, Bishop DT, Spector TD, Montgomery GW.
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| Am J Hum Genet 87(1):6-16. Epub 2010 Jun 17.PMID: 20602913 2010
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| 14 | IRF4
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| Interleukin-4 induced interferon regulatory factor (Irf) 4 participates in the regulation of alternative macrophage priming.
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| El Chartouni C, Schwarzfischer L, Rehli M.
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| Immunobiology 215(9-10):821-5. Epub 2010 Jun 4.PMID: 20580461 2010
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| 15 | IRF4
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| Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4.
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| Carreras E, Turner S, Frank MB, Knowlton N, Osban J, Centola M, Park CG, Simmons A, Alberola-Ila J, Kovats S.
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| Blood 115(2):238-46. Epub 2009 Oct 30.PMID: 19880499 2010
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| 16 | IRF4
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| IRF4 selectively controls cytokine gene expression in chronic intestinal inflammation.
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| Mudter J, Yu J, Amoussina L, Weigmann B, Hoffman A, Rücknagel K, Galle PR, Neurath MF.
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| Arch Immunol Ther Exp (Warsz) 57(5):369-76. Epub 2009 Aug 20.PMID: 19693649 2009
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| 17 | IRF4
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| IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines.
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| Ahyi AN, Chang HC, Dent AL, Nutt SL, Kaplan MH.
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| J Immunol 183(3):1598-606. Epub 2009 Jul 10.PMID: 19592658 2009
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| 18 | IRF4
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| Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses.
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| Zheng Y, Chaudhry A, Kas A, deRoos P, Kim JM, Chu TT, Corcoran L, Treuting P, Klein U, Rudensky AY.
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| Nature 458(7236):351-6. Epub 2009 Feb 1.PMID: 19182775 2009
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| 19 | IRF4
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| IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype.
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| Huber M, Brüstle A, Reinhard K, Guralnik A, Walter G, Mahiny A, von Löw E, Lohoff M.
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| Proc Natl Acad Sci U S A 105(52):20846-51. Epub 2008 Dec 16.PMID: 19088203 2008
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| 20 | IRF4, SLC24A4
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| A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
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| Han J, Kraft P, Nan H, Guo Q, Chen C, Qureshi A, Hankinson SE, Hu FB, Duffy DL, Zhao ZZ, Martin NG, Montgomery GW, Hayward NK, Thomas G, Hoover RN, Chanock S, Hunter DJ.
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| PLoS Genet 4(5):e1000074. doi: 10.1371/journal.pgen.1000074.
2008
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| 21 | IRF4
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| Down-regulation of interferon regulatory factor 4 gene expression in leukemic cells due to hypermethylation of CpG motifs in the promoter region.
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| Ortmann CA, Burchert A, Holzle K, Nitsche A, Wittig B, Neubauer A, Schmidt M.
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| Nucleic Acids Res 33(21):6895-905. Print 2005. 2005
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| 22 | IRF4
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| Identification of a novel GC-rich binding protein that binds to an indispensable element for constitutive IRF-4 promoter activity in B cells.
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| Nishiya N, Yamamoto K, Imaizumi Y, Kohno T, Matsuyama T.
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| Mol Immunol 41(9):855-61. 2004
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| 23 | IRF4
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| IRF-4 activities in HTLV-I-induced T cell leukemogenesis.
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| Mamane Y, Sharma S, Grandvaux N, Hernandez E, Hiscott J.
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| J Interferon Cytokine Res 22(1):135-43. Review. 2002
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| 24 | IRF4
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| MUM1/IRF4 expression is an unfavorable prognostic factor in B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).
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| Ito M, Iida S, Inagaki H, Tsuboi K, Komatsu H, Yamaguchi M, Nakamura N, Suzuki R, Seto M, Nakamura S, Morishima Y, Ueda R.
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| Jpn J Cancer Res 93(6):685-94. 2002
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| 25 | IRF4
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| Repression of IRF-4 target genes in human T cell leukemia virus-1 infection.
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| Mamane Y, Grandvaux N, Hernandez E, Sharma S, Innocente SA, Lee JM, Azimi N, Lin R, Hiscott J.
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| Oncogene 21(44):6751-65. 2002
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| 26 | IRF4
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| Possible involvement of interferon regulatory factor 4 (IRF4) in a clinical subtype of adult T-cell leukemia.
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| Imaizumi Y, Kohno T, Yamada Y, Ikeda S, Tanaka Y, Tomonaga M, Matsuyama T.
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| Jpn J Cancer Res 92(12):1284-92. 2001
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| 27 | IRF4
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| MUM1/IRF4 expression as a frequent event in mature lymphoid malignancies.
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| Tsuboi K, Iida S, Inagaki H, Kato M, Hayami Y, Hanamura I, Miura K, Harada S, Kikuchi M, Komatsu H, Banno S, Wakita A, Nakamura S, Eimoto T, Ueda R.
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| Leukemia 14(3):449-56. 2000
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| 28 | FKBP4, IRF4
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| Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52.
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| Mamane Y, Sharma S, Petropoulos L, Lin R, Hiscott J.
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| Immunity 12(2):129-40. 2000
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| 29 | IRF4, IRF8
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| Differential expression and distinct functions of IFN regulatory factor 4 and IFN consensus sequence binding protein in macrophages.
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| Marecki S, Atchison ML, Fenton MJ.
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| J Immunol 163(5):2713-22.PMID: 10453013 1999
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| 30 | IRF4
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| Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25.
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| Grossman A, et al.
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| Genomics 37 : 229-233. 1996
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