Citations for
1FBXL5, HERC2, IREB2
HERC2 Targets the Iron Regulator FBXL5 for Degradation and Modulates Iron Metabolism.
Moroishi T, Yamauchi T, Nishiyama M, Nakayama KI.
J Biol Chem 289(23):16430-41. doi: 10.1074/jbc.M113.541490. Epub 2014 Apr 28. 2014
2FBXL5, IREB2
F-box and leucine-rich repeat protein 5 (FBXL5) is required for maintenance of cellular and systemic iron homeostasis.
Ruiz JC, Walker SD, Anderson SA, Eisenstein RS, Bruick RK.
J Biol Chem 288(1):552-60. doi: 10.1074/jbc.M112.426171. Epub 2012 Nov 7. 2013
3FBXL5, IREB2
Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms.
Chollangi S, Thompson JW, Ruiz JC, Gardner KH, Bruick RK.
J Biol Chem 287(28):23710-7. doi: 10.1074/jbc.M112.360404. Epub 2012 May 30. 2012
4FBXL5, IREB2
The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.
Moroishi T, Nishiyama M, Takeda Y, Iwai K, Nakayama KI.
Cell Metab 14(3):339-51. doi: 10.1016/j.cmet.2011.07.011. 2011
5IREB2
The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study.
Chappell SL, Daly L, Lotya J, Alsaegh A, Guetta-Baranes T, Roca J, Rabinovich R, Morgan K, Millar AB, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, Kalsheker N.
BMC Med Genet 12:24. doi: 10.1186/1471-2350-12-24. 2011
6IREB2
Iron regulatory protein 2 turnover through a nonproteasomal pathway.
Chang AH, Jeong J, Levine RL.
J Biol Chem 286(27):23698-707. doi: 10.1074/jbc.M110.216788. Epub 2011 May 10. 2011
7ACO1, IREB2
Iron regulatory proteins secure mitochondrial iron sufficiency and function.
Galy B, Ferring-Appel D, Sauer SW, Kaden S, Lyoumi S, Puy H, Kölker S, Gröne HJ, Hentze MW.
Cell Metab 12(2):194-201. doi: 10.1016/j.cmet.2010.06.007. 2010
8IREB2
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene.
DeMeo DL, Mariani T, Bhattacharya S, Srisuma S, Lange C, Litonjua A, Bueno R, Pillai SG, Lomas DA, Sparrow D, Shapiro SD, Criner GJ, Kim HP, Chen Z, Choi AM, Reilly J, Silverman EK.
Am J Hum Genet 85(4):493-502. 2009
9FBXL5, IREB2
Control of iron homeostasis by an iron-regulated ubiquitin ligase.
Vashisht AA, Zumbrennen KB, Huang X, Powers DN, Durazo A, Sun D, Bhaskaran N, Persson A, Uhlen M, Sangfelt O, Spruck C, Leibold EA, Wohlschlegel JA.
Science 326(5953):718-21. Epub 2009 Sep 17.PMID: 19762596 2009
10FBXL5, IREB2
An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis.
Salahudeen AA, Thompson JW, Ruiz JC, Ma HW, Kinch LN, Li Q, Grishin NV, Bruick RK.
Science 326(5953):722-6. Epub 2009 Sep 17.PMID: 19762597 2009
11IREB2, RBCK1
HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells.
Zumbrennen KB, Hanson ES, Leibold EA.
Biochim Biophys Acta 1783(2):246-52. Epub 2007 Aug 9.PMID: 17822790 2008
12ACO1, IREB2
Excess capacity of the iron regulatory protein system.
Wang W, Di X, D'Agostino RB Jr, Torti SV, Torti FM.
J Biol Chem 282(34):24650-9. Epub 2007 Jun 28. 2007
13ACO1, IREB2
Human iron regulatory protein 2 is easily cleaved in its specific domain: consequences for the haem binding properties of the protein.
Dycke C, Bougault C, Gaillard J, Andrieu JP, Pantopoulos K, Moulis JM.
Biochem J 408(3):429-39.PMID: 17760563 2007
14IREB2
Characterization and expression of iron regulatory protein 2 (IRP2). Presence of multiple IRP2 transcriped regulated by intracellular iron levels.
Guo B, et al.
J Biol Chem 270 : 16529-16535. 1995
15ACO1, IREB2
Structural relationship beetween an iron-regulated RNA-binding protein (IRE-BP) and aconitase : functional implications.
Rouault TA, et al.
Cell 64 : 881-883. 1991
16IREB2
Cloning of the cDNA encoding an RNA regulatory protein-the human iron-responsive element-binding protein.
Rouault TA, et al.
Proc Natl Acad Sci U S A 87 : 7958-7962. 1990