1 | IRAK1BP1, MED1
|
| SIMPL enhancement of tumor necrosis factor-α dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function.
|
| Zhao W, Breese E, Bowers A, Hoggatt J, Pelus LM, Broxmeyer HE, Goebl M, Harrington MA.
|
| PLoS One 8(4):e61123. doi: 10.1371/journal.pone.0061123. Print 2013.
2013
|
2 | IRAK1BP1
|
| Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors.
|
| Benson EA, Goebl MG, Yang FC, Kapur R, McClintick J, Sanghani S, Clapp DW, Harrington MA.
|
| Exp Hematol 38(2):71-81. Epub 2009 Nov 23.PMID: 19941935 2010
|
3 | IRAK1BP1
|
| IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF-kappaB p50.
|
| Conner JR, Smirnova II, Moseman AP, Poltorak A.
|
| Proc Natl Acad Sci U S A 107(25):11477-82. Epub 2010 Jun 7.PMID: 20534545 2010
|
4 | IRAK1BP1
|
| Forward genetic analysis of Toll-like receptor responses in wild-derived mice reveals a novel antiinflammatory role for IRAK1BP1.
|
| Conner JR, Smirnova II, Poltorak A.
|
| J Exp Med 205(2):305-14. Epub 2008 Feb 11.PMID: 18268037 2008
|
5 | IRAK1BP1
|
| Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription.
|
| Luo Y, Kwon HJ, Montano S, Georgiadis M, Goebl MG, Harrington MA.
|
| Am J Physiol Cell Physiol 292(3):C1013-23. Epub 2006 Nov 1.PMID: 17079333 2007
|
6 | IRAK1BP1
|
| The disordered amino-terminus of SIMPL interacts with members of the 70-kDa heat-shock protein family.
|
| Haag Breese E, Uversky VN, Georgiadis MM, Harrington MA.
|
| DNA Cell Biol 25(12):704-14.PMID: 17233114 2006
|
7 | IRAK1BP1, RELA
|
| Tumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL.
|
| Kwon HJ, Breese EH, Vig-Varga E, Luo Y, Lee Y, Goebl MG, Harrington MA.
|
| Mol Cell Biol 24(21):9317-26.PMID: 15485901 2004
|
8 | IRAK1BP1
|
| SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity.
|
| Vig E, Green M, Liu Y, Yu KY, Kwon HJ, Tian J, Goebl MG, Harrington MA.
|
| J Biol Chem 276(11):7859-66. Epub 2000 Nov 28. 2001
|