1 | INSL3, NR2F2, NR5A1
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| The nuclear receptors SF1 and COUP-TFII cooperate on the Insl3 promoter in Leydig cells.
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| Di-Luoffo M, Pierre KJ, Robert NM, Girard MJ, Tremblay JJ.
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| Reproduction. Jun 27;164(2):31-40. doi: 10.1530/REP-22-0109. 2022
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2 | EEF1AKNMT, INSL3
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| FEAT enhances INSL3 expression in testicular Leydig cells.
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| Li Y, Kobayashi K, Murayama K, Kawahara K, Shima Y, Suzuki A, Tani K, Takahashi A.
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| Genes Cells 23(11):952-962. doi: 10.1111/gtc.12644. Epub 2018 Oct 2.
2018
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3 | INSL3, RXFP2
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| Mutations in INSL3 and RXFP2 genes in cryptorchid boys.
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| Ferlin A, Zuccarello D, Garolla A, Selice R, Vinanzi C, Ganz F, Zanon GF, Zuccarello B, Foresta C.
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| Ann N Y Acad Sci 1160:213-4.PMID: 19416190 2009
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4 | INSL3, RXFP2
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| INSL3/RXFP2 signaling in testicular descent.
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| Feng S, Ferlin A, Truong A, Bathgate R, Wade JD, Corbett S, Han S, Tannour-Louet M, Lamb DJ, Foresta C, Agoulnik AI.
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| Ann N Y Acad Sci 1160:197-204. Review.PMID: 19416188 2009
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5 | INSL3
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| Insulin-like factor 3 levels in amniotic fluid of human male fetuses.
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| Anand-Ivell R, Ivell R, Driscoll D, Manson J.
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| Hum Reprod 23(5):1180-6. Epub 2008 Feb 29. 2008
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6 | INSL3, RXFP2
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| Mutations in the insulin-like factor 3 receptor are associated with osteoporosis.
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| Ferlin A, Pepe A, Gianesello L, Garolla A, Feng S, Giannini S, Zaccolo M, Facciolli A, Morello R, Agoulnik AI, Foresta C.
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| J Bone Miner Res 23(5):683-93.PMID: 18433302 2008
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7 | INSL3, RXFP2
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| Defining the LGR8 residues involved in binding insulin-like peptide 3.
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| Scott DJ, Wilkinson TN, Zhang S, Ferraro T, Wade JD, Tregear GW, Bathgate RA.
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| Mol Endocrinol 21(7):1699-712. Epub 2007 May 1.
2007
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8 | INSL3, INSL5, INSL6
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| Relaxin and related peptides in male reproduction.
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| Agoulnik AI.
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| Adv Exp Med Biol 612:49-64. Review.PMID: 18161481 2007
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9 | INSL3, RXFP2
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| Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.
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| Rosengren KJ, Zhang S, Lin F, Daly NL, Scott DJ, Hughes RA, Bathgate RA, Craik DJ, Wade JD.
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| J Biol Chem 281(38):28287-95. Epub 2006 Jul 25. 2006
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10 | INSL3, INSL5, INSL6
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| Evolution of the relaxin-like peptide family: from neuropeptide to reproduction.
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| Wilkinson TN, Speed TP, Tregear GW, Bathgate RA.
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| Ann N Y Acad Sci 1041:530-3.PMID: 15956756 2005
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11 | INSL3, INSL4, INSL5, INSL6
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| Evolution of the relaxin-like peptide family.
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| Wilkinson TN, Speed TP, Tregear GW, Bathgate RA.
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| BMC Evol Biol 5(1):14.PMID: 15707501 2005
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12 | INSL3,RXFP2
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| The INSL3-LGR8/GREAT ligand-receptor pair in human cryptorchidism.
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| Ferlin A, Simonato M, Bartoloni L, Rizzo G, Bettella A, Dottorini T, Dallapiccola B, Foresta C.
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| J Clin Endocrinol Metab 88(9):4273-9. 2003
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13 | INSL3,RXFP2
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| INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent.
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| Kumagai J, Hsu SY, Matsumi H, Roh JS, Fu P, Wade JD, Bathgate RA, Hsueh AJ.
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| J Biol Chem 277(35):31283-6. Epub 2002 Jul 11. 2002
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14 | INSL3
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| Genetic analysis of the INSL3 gene in patients with maldescent of the testis.
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| Lim HN, Raipert-de Meyts E, Skakkebaek NE, Hawkins JR, Hughes IA.
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| Eur J Endocrinol 144(2):129-37. 2001
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15 | INSL3, JAK3
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| JAK3: expression and mapping to chromosome 19p12-13.1.
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| Safford MG, Levenstein M, Tsifrina E, Amin S, Hawkins AL, Griffin CA, Civin CI, Small D.
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| Exp Hematol 25(5):374-86. 1997
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16 | INSL3
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| Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3).
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| Burkhardt E, et al.
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| Genomics 20 : 13-19. 1994
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