| 1 | INPP5J, KCNE1, KCNQ1
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| Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking.
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| Royal AA, Tinker A, Harmer SC.
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| PLoS One 12(10):e0186293. doi: 10.1371/journal.pone.0186293. eCollection 2017.
2017
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| 2 | INPP4B, INPP5J, PTEN
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| Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases.
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| Rodgers SJ, Ferguson DT, Mitchell CA, Ooms LM.
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| Biosci Rep 37(1). pii: BSR20160432. doi: 10.1042/BSR20160432. Print 2017 Feb 28. Review.
2017
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| 3 | INPP5E, INPP5J
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| Regulation of PtdIns(3,4,5)P3/Akt signalling by inositol polyphosphate 5-phosphatases.
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| Eramo MJ, Mitchell CA.
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| Biochem Soc Trans 44(1):240-52. doi: 10.1042/BST20150214. Review.
2016
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| 4 | INPP5J, PLCB.3, TRPM4
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| PIP2 and PIP3 interact with N-terminus region of TRPM4 channel.
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| Bousova K, Jirku M, Bumba L, Bednarova L, Sulc M, Franek M, Vyklicky L, Vondrasek J, Teisinger J.
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| Biophys Chem 205:24-32. doi: 10.1016/j.bpc.2015.06.004. [Epub ahead of print]
2015
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| 5 | INPP5J, TRPM1
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| Characterization of the part of N-terminal PIP2 binding site of the TRPM1 channel.
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| Jirku M, Bumba L, Bednarova L, Kubala M, Sulc M, Franek M, Vyklicky L, Vondrasek J, Teisinger J, Bousova K.
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| Biophys Chem 207:135-42. doi: 10.1016/j.bpc.2015.10.005. Epub 2015 Oct 27.
2015
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| 6 | INPP5J
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| The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis.
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| Ooms LM, Binge LC, Davies EM, Rahman P, Conway JR, Gurung R, Ferguson DT, Papa A, Fedele CG, Vieusseux JL, Chai RC, Koentgen F, Price JT, Tiganis T, Timpson P, McLean CA, Mitchell CA.
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| Cancer Cell 28(2):155-69. doi: 10.1016/j.ccell.2015.07.003.
2015
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| 7 | INPP5J, VCL
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| Lipid binding promotes oligomerization and focal adhesion activity of vinculin.
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| Chinthalapudi K, Rangarajan ES, Patil DN, George EM, Brown DT, Izard T.
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| J Cell Biol 207(5):643-56. doi: 10.1083/jcb.201404128.
2014
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| 8 | EHD2, INPP5J
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| Role of phosphatidylinositol 4,5-bisphosphate in regulating EHD2 plasma membrane localization.
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| Simone LC, Caplan S, Naslavsky N.
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| PLoS One 8(9):e74519. doi: 10.1371/journal.pone.0074519. eCollection 2013.
2013
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| 9 | ESYT1, INPP5J, PITPNM1
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| Feedback regulation of receptor-induced Ca2+ signaling mediated by E-Syt1 and Nir2 at endoplasmic reticulum-plasma membrane junctions.
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| Chang CL, Hsieh TS, Yang TT, Rothberg KG, Azizoglu DB, Volk E, Liao JC, Liou J.
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| Cell Rep 5(3):813-25. doi: 10.1016/j.celrep.2013.09.038. Epub 2013 Oct 31.
2013
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| 10 | ARHGEF7, FRMPD4, INPP5J
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| Preso regulation of dendritic outgrowth through PI(4,5)P2-dependent PDZ interaction with βPix.
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| Mo J, Lee D, Hong S, Han S, Yeo H, Sun W, Choi S, Kim H, Lee HW.
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| Eur J Neurosci 36(1):1960-70. doi: 10.1111/j.1460-9568.2012.08124.x. Epub 2012 May 17.
2012
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| 11 | BASP1, INPP5J, WT1
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| Repression of transcription by WT1-BASP1 requires the myristoylation of BASP1 and the PIP2-dependent recruitment of histone deacetylase.
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| Toska E, Campbell HA, Shandilya J, Goodfellow SJ, Shore P, Medler KF, Roberts SG.
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| Cell Rep 2(3):462-9. doi: 10.1016/j.celrep.2012.08.005. Epub 2012 Aug 30. 2012
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| 12 | INPP5J, KCNT1, KCNT2
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| PIP₂ modulation of Slick and Slack K⁺ channels.
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| de los Angeles Tejada M, Jensen LJ, Klaerke DA.
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| Biochem Biophys Res Commun 424(2):208-13. doi: 10.1016/j.bbrc.2012.06.038. Epub 2012 Jun 21.
2012
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| 13 | INPP5J, PIRT, TRPV1
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| Localization of the PIP2 sensor of TRPV1 ion channels.
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| Ufret-Vincenty CA, Klein RM, Hua L, Angueyra J, Gordon SE.
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| J Biol Chem 286(11):9688-98. Epub 2011 Jan 11.
2011
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| 14 | DPYSL2, INPP5J
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| Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)•collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.
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| Astle MV, Ooms LM, Cole AR, Binge LC, Dyson JM, Layton MJ, Petratos S, Sutherland C, Mitchell CA.
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| J Biol Chem 286(26):23407-18. Epub 2011 May 6.
2011
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| 15 | INPP5J, KCNJ6
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| Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium.
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| Whorton MR, MacKinnon R.
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| Cell 147(1):199-208.
2011
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| 16 | INPP5J, KCNJ12
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| Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2.
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| Hansen SB, Tao X, MacKinnon R.
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| Nature 477(7365):495-8. doi: 10.1038/nature10370.
2011
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| 17 | ABCC8, INPP5J, KCNJ11
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| N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2.
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| Pratt EB, Tewson P, Bruederle CE, Skach WR, Shyng SL.
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| J Gen Physiol 137(3):299-314. doi: 10.1085/jgp.201010557. Epub 2011 Feb 14.
2011
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| 18 | INPP5J, NOX5
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| Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an N-terminal polybasic region.
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| Kawahara T, Lambeth JD.
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| Mol Biol Cell 19(10):4020-31. Epub 2008 Jul 9.PMID: 18614798 2008
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| 19 | INPP5J, SCAMP2
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| Secretory carrier membrane protein SCAMP2 and phosphatidylinositol 4,5-bisphosphate interactions in the regulation of dense core vesicle exocytosis.
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| Liao H, Ellena J, Liu L, Szabo G, Cafiso D, Castle D.
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| Biochemistry 46(38):10909-20. Epub 2007 Aug 22.PMID: 17713930 2007
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| 20 | INPP5J
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| The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.
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| Ooms LM, Fedele CG, Astle MV, Ivetac I, Cheung V, Pearson RB, Layton MJ, Forrai A, Nandurkar HH, Mitchell CA.
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| Mol Biol Cell 17(2):607-22. Epub 2005 Nov 9. 2006
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| 21 | INPP5J, INPP5K
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| Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation.
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| Gurung R, Tan A, Ooms LM, McGrath MJ, Huysmans RD, Munday AD, Prescott M, Whisstock JC, Mitchell CA.
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| J Biol Chem 278(13):11376-85. Epub 2003 Jan 20. 2003
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| 22 | ADPRTL4, ADTB1L1, ADTB1L2, ALG12, APOL2, ARHGAP8, ATP6V1E1, BCRL2, BCRL3, BCRL4, BCRL5, BCRL6, BRD1, CBX6, CBY1, CSF2RB2, DRG1, FAM108A5, FAM115B, HMG17L1, HMG17L2, HMGB1L10, INPP5J, MAFF, MAPK11, MPPED1, OSBP2, P2RX6, PATZ1, PITPNB, PPIL2, PRAME, PTPNS1L, RBX1, RHBDD3, RPL32L2, SBF1, SDF2L1, SEZ6L, SFI1, SH3BP1, SNAP29, TBC1D22A, TMEM184B, TOP3B2, TSSK1A, YME1L2, ZNF280A, ZNF280B
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| The DNA sequence of human chromosome 22.
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| Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al.
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| Nature 402(6761):489-95. 1999
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| 23 | INPP5J
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| Novel inositol polyphosphate 5-phosphatase localizes at membrane ruffles.
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| Mochizuki Y, Takenawa T.
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| J Biol Chem 274(51):36790-5. Erratum in: J Biol Chem 2000 Jul 7;275(27):20956. 1999
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