Citations for
1ILK, MYH1, MYH4, MYH7
Evidence for skeletal muscle fiber type-specific expressions of mechanosensors.
Mathes S, Vanmunster M, Bloch W, Suhr F
Cell Mol Life Sci. Aug;76(15):2987-3004. doi: 10.1007/s00018-019-03026-3. Epub 2019 Jan 30 2019
2ELMO2, ILK, RHOG
An ELMO2-RhoG-ILK network modulates microtubule dynamics.
Jackson BC, Ivanova IA, Dagnino L.
Mol Biol Cell 26(14):2712-25. doi: 10.1091/mbc.E14-10-1444. Epub 2015 May 20. 2015
3ILK, PRKCA
Protein kinase Cα and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog.
Guo D, Standley C, Bellve K, Fogarty K, Bao ZZ.
Mol Cell Neurosci 50(1):82-92. doi: 10.1016/j.mcn.2012.03.008. Epub 2012 Apr 2. 2012
4ILK
Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer.
Li R, Liu B, Yin H, Sun W, Yin J, Su Q.
J Mol Histol Mol Histol. 2012 Oct 31. [Epub ahead of print] 2012
5ILK
Targeting ILK and â4 integrin abrogates the invasive potential of ovarian cancer.
Choi YP, Kim BG, Gao MQ, Kang S, Cho NH.
Biochem Biophys Res Commun 427(3):642-8. doi: 10.1016/j.bbrc.2012.09.114. Epub 2012 Sep 28. 2012
6ILK
Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF).
Serrano I, Díez-Marqués ML, Rodríguez-Puyol M, Herrero-Fresneda I, Raimundo García del M, Dedhar S, Ruiz-Torres MP, Rodríguez-Puyol D.
Exp Cell Res 318(19):2470-81. doi: 10.1016/j.yexcr.2012.08.001. Epub 2012 Aug 23. 2012
7ILK
Integrin-Linked Kinase (ILK) Expression Correlates with Tumor Severity in Clear Cell Renal Carcinoma.
Engelman MD, Grande RM, Naves MA, de Franco MF, de Paulo Castro Teixeira V.
Pathol Oncol Res athol Oncol Res. 2012 Jul 20. [Epub ahead of print] 2012
8ADAM12, ILK
Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival.
Leyme A, Bourd-Boittin K, Bonnier D, Falconer A, Arlot-Bonnemains Y, Théret N.
Mol Biol Cell 23(17):3461-72. doi: 10.1091/mbc.E11-11-0918. Epub 2012 Jul 5. 2012
9ILK
ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling.
Qin J, Wu C.
Curr Opin Cell Biol 24(5):607-13. doi: 10.1016/j.ceb.2012.06.003. Epub 2012 Jul 2. 2012
10ELMO2, ILK
Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways.
Ho E, Dagnino L.
Cell Adh Migr 6(3):168-72. doi: 10.4161/cam.20399. Epub 2012 May 1. 2012
11CKAP5, ILK, TACC3
A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.
Fielding AB, Lim S, Montgomery K, Dobreva I, Dedhar S.
Oncogene 30(5):521-34. Epub 2010 Sep 13. 2011
12ILK
Identification and characterization of a novel integrin-linked kinase inhibitor.
Lee SL, Hsu EC, Chou CC, Chuang HC, Bai LY, Kulp SK, Chen CS.
J Med Chem 54(18):6364-74. doi: 10.1021/jm2007744. Epub 2011 Aug 24. 2011
13ILK
Small interfering RNA targeting integrin-linked kinase inhibited the growth and induced apoptosis in human bladder cancer cells.
Gao J, Zhu J, Li HY, Pan XY, Jiang R, Chen JX.
Int J Biochem Cell Biol 43(9):1294-304. doi: 10.1016/j.biocel.2011.05.003. Epub 2011 May 11. 2011
14ILK
Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.
Fukuda K, Knight JD, Piszczek G, Kothary R, Qin J.
J Biol Chem 286(24):21886-95. doi: 10.1074/jbc.M111.240093. Epub 2011 Apr 26. 2011
15ILK
Integrin-linked kinase: a Scaffold protein unique among its ilk.
Dagnino L.
J Cell Commun Signal 5(2):81-3. doi: 10.1007/s12079-011-0124-4. Epub 2011 Mar 3. 2011
16ILK
Integrin-linked kinase 1: role in hormonal cancer progression.
Cortez V, Nair BC, Chakravarty D, Vadlamudi RK.
Front Biosci (Schol Ed) 3:788-96. Review. 2011
17ILK
Integrin-linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin-dependent mechanism.
Gagné D, Groulx JF, Benoit YD, Basora N, Herring E, Vachon PH, Beaulieu JF.
J Cell Physiol 222(2):387-400.PMID: 19885839 2010
18ILK
Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae.
Wickström SA, Lange A, Hess MW, Polleux J, Spatz JP, Krüger M, Pfaller K, Lambacher A, Bloch W, Mann M, Huber LA, Fässler R.
Dev Cell 19(4):574-88. doi: 10.1016/j.devcel.2010.09.007. 2010
19ARRB1, EDN1, ILK
Beta-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase.
Cianfrocca R, Rosanò L, Spinella F, Di Castro V, Natali PG, Bagnato A.
Can J Physiol Pharmacol 88(8):796-801. doi: 10.1139/Y10-052. 2010
20ILK, PARVA
The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Fukuda K, Gupta S, Chen K, Wu C, Qin J.
Mol Cell 36(5):819-30.PMID: 20005845 2009
21ILK
The mitotic functions of integrin-linked kinase.
Fielding AB, Dedhar S.
Cancer Metastasis Rev 28(1-2):99-111. Review.PMID: 19153670 2009
22ELMO2, ILK, RHOG
Integrin-linked kinase interactions with ELMO2 modulate cell polarity.
Ho E, Irvine T, Vilk GJ, Lajoie G, Ravichandran KS, D'Souza SJ, Dagnino L.
Mol Biol Cell 20(13):3033-43. Epub 2009 May 13.PMID: 19439446 2009
23EPHA1, ILK
EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility.
Yamazaki T, Masuda J, Omori T, Usui R, Akiyama H, Maru Y.
J Cell Sci 122(Pt 2):243-55. doi: 10.1242/jcs.036467. 2009
24RICTOR, ILK
Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.
McDonald PC, Oloumi A, Mills J, Dobreva I, Maidan M, Gray V, Wederell ED, Bally MB, Foster LJ, Dedhar S.
Cancer Res 68(6):1618-24. 2008
25ILK, LIMS1
The structural basis of integrin-linked kinase-PINCH interactions.
Chiswell BP, Zhang R, Murphy JW, Boggon TJ, Calderwood DA.
Proc Natl Acad Sci U S A 105(52):20677-82. Epub 2008 Dec 12.PMID: 19074270 2008
26ILK
ILK overexpression in human hepatocellular carcinoma and liver cirrhosis correlates with activation of Akt.
Peroukides S, Bravou V, Varakis J, Alexopoulos A, Kalofonos H, Papadaki H.
Oncol Rep 20(6):1337-44.PMID: 19020711 2008
27ILK, ILKAP, XPO1
Modulation of integrin-linked kinase nucleo-cytoplasmic shuttling by ILKAP and CRM1.
Nakrieko KA, Vespa A, Mason D, Irvine TS, D'Souza SJ, Dagnino L.
Cell Cycle 7(14):2157-66. Epub 2008 May 7.PMID: 18635968 2008
28ILK, LAMA4
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells.
Knöll R, Postel R, Wang J, Krätzner R, Hennecke G, Vacaru AM, Vakeel P, Schubert C, Murthy K, Rana BK, Kube D, Knöll G, Schäfer K, Hayashi T, Holm T, Kimura A, Schork N, Toliat MR, Nürnberg P, Schultheiss HP, Schaper W, Schaper J, Bos E, Den Hertog J, van Eeden FJ, Peters PJ, Hasenfuss G, Chien KR, Bakkers J.
Circulation 116(5):515-25. Epub 2007 Jul 23. 2007
29CNKSR3, ILK
Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase.
Acconcia F, Barnes CJ, Singh RR, Talukder AH, Kumar R.
Proc Natl Acad Sci U S A 104(16):6782-7. Epub 2007 Apr 9. 2007
30TMSB4X, TMSB4Y, ILK, LIMS1
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair.
Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D.
Nature 432(7016):466-72. 2004
31ILK, ILKAP
ILKAP regulates ILK signaling and inhibits anchorage-independent growth.
Kumar AS, Naruszewicz I, Wang P, Leung-Hagesteijn C, Hannigan GE.
Oncogene 23(19):3454-61. 2004
32ILK
Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1.
Melchior C, Kreis S, Janji B, Kieffer N.
Biochim Biophys Acta 1575(1-3):117-22. 2002
33ILK
Role of integrin-linked kinase in leukocyte recruitment.
Friedrich EB, Sinha S, Li L, Dedhar S, Force T, Rosenzweig A, Gerszten RE.
J Biol Chem 277(19):16371-5. 2002
34CLN2,ILK, CLN2, TAF10, TPP1
Structural organization and sequence of CLN2, the defective gene in classical late infantile neuronal ceroid lipofuscinosis.
Liu CG, Sleat DE, Donnelly RJ, Lobel P.
Genomics 50 : 206-212. 1998
35ILK
Mapping of the gene encoding the integrin-linked kinase, ILK, to human chromosome 11p15.5-p15.4.
Hannigan GE, Bayani J, Weksberg R, Beatty B, Pandita A, Dedhar S, Squire J.
Genomics 42(1):177-9. 1997
36ILK
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.
Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, Bell JC, Dedhar S.
Nature 379(6560):91-6. 1996