Citations for
1F2RL1, IL8, TMPRSS11D
Human airway trypsin-like protease enhances interleukin-8 synthesis in bronchial epithelial cells by activating protease-activated receptor 2.
Miki M, Yasuoka S, Tsutsumi R, Nakamura Y, Hajime M, Takeuchi Y, Miki K, Kitada S, Maekura R.
Arch Biochem Biophys 664:167-173. doi: 10.1016/j.abb.2019.01.019. Epub 2019 Jan 21. 2019
2CXCR1, IL8
Dynamics-Derived Insights into Complex Formation between the CXCL8 Monomer and CXCR1 N-Terminal Domain: An NMR Study.
Joseph PRB, Spyracopoulos L, Rajarathnam K.
Molecules 23(11). pii: E2825. doi: 10.3390/molecules23112825. 2018
3CNOT1, CNOT7, ICAM1, IL8
CNOT1 is involved in TTP‑mediated ICAM‑1 and IL‑8 mRNA decay.
Shi JX, Li JS, Hu R, Zhao XC, Liang CC, Li XM, Wang H, Shi Y, Su X.
Mol Med Rep 18(2):2321-2327. doi: 10.3892/mmr.2018.9213. Epub 2018 Jun 22. 2018
4CXCR1, IL8
Interaction of Monomeric Interleukin-8 with CXCR1 Mapped by Proton-Detected Fast MAS Solid-State NMR.
Park SH, Berkamp S, Radoicic J, De Angelis AA, Opella SJ.
Biophys J 113(12):2695-2705. doi: 10.1016/j.bpj.2017.09.041. 2017
5CXCR1, IL8
Structure of monomeric Interleukin-8 and its interactions with the N-terminal Binding Site-I of CXCR1 by solution NMR spectroscopy.
Berkamp S, Park SH, De Angelis AA, Marassi FM, Opella SJ.
J Biomol NMR 69(3):111-121. doi: 10.1007/s10858-017-0128-3. Epub 2017 Nov 15. 2017
6CXCL1, IL8, STAT3
Endoplasmic Reticulum Stress and Chemokine Production in Cystic Fibrosis Airway Cells: Regulation by STAT3 Modulation.
Tang AC, Saferali A, He G, Sandford AJ, Strug LJ, Turvey SE.
J Infect Dis 215(2):293-302. doi: 10.1093/infdis/jiw516. 2017
7GPR68, IL8
Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells.
Chandra V, Karamitri A, Richards P, Cormier F, Ramond C, Jockers R, Armanet M, Albagli-Curiel O, Scharfmann R.
Sci Rep 6:25765. doi: 10.1038/srep25765. 2016
8CXCR1, IL8
Solution NMR characterization of WT CXCL8 monomer and dimer binding to CXCR1 N-terminal domain.
Joseph PR, Rajarathnam K.
Protein Sci 24(1):81-92. doi: 10.1002/pro.2590. Epub 2014 Nov 28. 2015
9BTC, IL8
Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells.
Shi L, Wang L, Wang B, Cretoiu SM, Wang Q, Wang X, Chen C.
J Transl Med 12:70. doi: 10.1186/1479-5876-12-70. 2014
10CXCR1, IL8
The IL-8/CXCR1 axis is associated with cancer stem cell-like properties and correlates with clinical prognosis in human pancreatic cancer cases.
Chen L, Fan J, Chen H, Meng Z, Chen Z, Wang P, Liu L.
Sci Rep 4:5911. doi: 10.1038/srep05911. 2014
11CXCR1, IL8
The dynamics of interleukin-8 and its interaction with human CXC receptor I peptide.
Kendrick AA, Holliday MJ, Isern NG, Zhang F, Camilloni C, Huynh C, Vendruscolo M, Armstrong G, Eisenmesser EZ.
Protein Sci 23(4):464-80. doi: 10.1002/pro.2430. Epub 2014 Feb 12. 2014
12IL1RL1, IL33, IL6, IL8, TMED1
The GOLD domain-containing protein TMED1 is involved in interleukin-33 signaling.
Connolly DJ, O'Neill LA, McGettrick AF.
J Biol Chem 288(8):5616-23. doi: 10.1074/jbc.M112.403899. Epub 2013 Jan 14. 2013
13CENPA, CENPB, IL8
Nap1 regulates proper CENP-B binding to nucleosomes.
Tachiwana H, Miya Y, Shono N, Ohzeki J, Osakabe A, Otake K, Larionov V, Earnshaw WC, Kimura H, Masumoto H, Kurumizaka H.
Nucleic Acids Res 41(5):2869-80. doi: 10.1093/nar/gks1464. Epub 2013 Jan 15. 2013
14ANO1, CFTR, IL8
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia.
Veit G, Bossard F, Goepp J, Verkman AS, Galietta LJ, Hanrahan JW, Lukacs GL.
Mol Biol Cell 23(21):4188-202. doi: 10.1091/mbc.E12-06-0424. Epub 2012 Sep 12. 2012
15IL8, SLC16A1
Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis.
Végran F, Boidot R, Michiels C, Sonveaux P, Feron O.
Cancer Res 71(7):2550-60. Epub 2011 Feb 7. 2011
16ENTPD1, IL8
NTPDase1 controls IL-8 production by human neutrophils.
Kukulski F, Bahrami F, Ben Yebdri F, Lecka J, Martín-Satué M, Lévesque SA, Sévigny J.
J Immunol 187(2):644-53. Epub 2011 Jun 13. 2011
17IL8
IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells.
Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C.
Cancer Res 71(15):5296-306. Epub 2011 Jun 8. 2011
18IL8, SNAI1
SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells.
Hwang WL, Yang MH, Tsai ML, Lan HY, Su SH, Chang SC, Teng HW, Yang SH, Lan YT, Chiou SH, Wang HW.
Gastroenterology 141(1):279-91, 291.e1-5. Epub 2011 Apr 16. 2011
19IL8
Interleukin-8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models.
Ning Y, Manegold PC, Hong YK, Zhang W, Pohl A, Lurje G, Winder T, Yang D, LaBonte MJ, Wilson PM, Ladner RD, Lenz HJ.
Int J Cancer 128(9):2038-49. doi: 10.1002/ijc.25562. 2011
20IL8
CXCL8 protects human neurons from amyloid-β-induced neurotoxicity: relevance to Alzheimer's disease.
Ashutosh, Kou W, Cotter R, Borgmann K, Wu L, Persidsky R, Sakhuja N, Ghorpade A.
Biochem Biophys Res Commun 412(4):565-71. Epub 2011 Aug 5. 2011
21CXCL13, IL8
IL8 and CXCL13 are potent chemokines for the recruitment of human neural precursor cells across brain endothelial cells.
Weiss N, Deboux C, Chaverot N, Miller F, Baron-Van Evercooren A, Couraud PO, Cazaubon S.
J Neuroimmunol 223(1-2):131-4. Epub 2010 Apr 18.PMID: 20400187 2010
22IL8
The Chemokine IL8 Is Up-Regulated in Bovine Endometrial Stromal Cells by the BoHV-4 IE2 Gene Product, ORF50/Rta: A Step Ahead Toward a Mechanism for BoHV-4 Induced Endometritis.
Donofrio G, Capocefalo A, Franceschi V, Price S, Cavirani S, Sheldon M.
Biol Reprod iol Reprod. 2010 Aug 18. [Epub ahead of print]PMID: 20720165 2010
23DEFA1, IL8
Differential effects of human neutrophil peptide-1 on growth factor and interleukin-8 production by human lung fibroblasts and epithelial cells.
Amenomori M, Mukae H, Ishimatsu Y, Sakamoto N, Kakugawa T, Hara A, Hara S, Fujita H, Ishimoto H, Hayashi T, Kohno S.
Exp Lung Res 36(7):411-9. 2010
24IL8
IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG.
J Immunol 184(3):1642-52. Epub 2009 Dec 21. 2010
25IL8, PXN
Cell migration to the chemokine CXCL8: paxillin is activated and regulates adhesion and cell motility.
Cohen-Hillel E, Mintz R, Meshel T, Garty BZ, Ben-Baruch A.
Cell Mol Life Sci 66(5):884-99. 2009
26CCL4, CXCL1, IL8, PROK1
Prokineticin 1 induces CCL4, CXCL1 and CXCL8 in human monocytes but not in macrophages and dendritic cells.
Monnier J, Quillien V, Piquet-Pellorce C, Leberre C, Preisser L, Gascan H, Samson M.
Eur Cytokine Netw 19(4):166-75.PMID: 19103522 2008
27IL8
Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer.
Araki S, Omori Y, Lyn D, Singh RK, Meinbach DM, Sandman Y, Lokeshwar VB, Lokeshwar BL.
Cancer Res 67(14):6854-62. 2007
28PYCARD, IL8
Regulation of the ASC expression in response to LPS stimulation is related to IL-8 secretion in the human intestinal mucosa.
Masumoto J, Kobayashi H, Nakamura T, Kaneko Y, Ota H, Hasegawa M, Kobayashi Y, Suzuki T, Matsuda K, Sano K, Katsuyama T, Inohara N.
Biochem Biophys Res Commun 346(3):968-73. Epub 2006 Jun 9. 2006
29CXCR1, CXCR2, IL8
The N- and C-terminal peptides of hIL8/CXCL8 are ligands for hCXCR1 and hCXCR2.
Li QJ, Yao M, Wong W, Parpura V, Martins-Green M.
FASEB J 18(6):776-8. Epub 2004 Feb 6. 2004
30TMPRSS11D, F2RL1, IL8
Human airway trypsin-like protease induces PAR-2-mediated IL-8 release in psoriasis vulgaris.
Iwakiri K, Ghazizadeh M, Jin E, Fujiwara M, Takemura T, Takezaki S, Kawana S, Yasuoka S, Kawanami O.
J Invest Dermatol 122(4):937-44. 2004
31IL8, CXCL1
IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation.
Merz D, Liu R, Johnson K, Terkeltaub R.
J Immunol 171(8):4406-15. 2003
32IL8, LTBR, TRAF2, TRAF3, TRAF5
Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation.
Chang YH, Hsieh SL, Chen MC, Lin WW.
Exp Cell Res 278(2):166-74. 2002
33IL8
Interleukin 8: an autocrine growth factor for malignant mesothelioma.
Galffy G, et al.
Cancer Res 59(2):367-71. 1999
34IER3, DUSP1, HIF1A, IL8,TNF, GIMAP4, AGPAT4
Cloning of ARE-containing genes by AU-motif-directed display.
Dominguez O, Ashhab Y, Sabater L, Belloso E, Caro P, Pujol-Borrell R.
Genomics 54(2):278-86. 1998
35IL1A, IL6, IL8, TNFRSF1A
Heterogeneity among human nasopharyngeal carcinoma cell lines for inflammatory cytokines mRNA expression levels.
Mahe Y, Hirose K, Clausse B, Chouaib S, Tursz T, Mariame B.
Biochem Biophys Res Commun 187(1):121-6. 1992
36IL8
Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8) resides in a gene cluster along with several other members of the platelet factor 4 gene superfamily.
Modi WS, et al.
Hum Genet 84 : 185-187. 1990
37IL8
Chromosome mapping and RFLP analyses of monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8).
Modi WS, et al.
(HGM10) Cytogenet Cell Genet 51 : 1046. 1989