| 1 | IL5, MARCHF2, MARCHF3
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| The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target IL-5 receptor alpha to negatively regulate eosinophilic airway inflammation
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| Zeng LW, Feng L, Liu R, Lin H, Shu HB, Li S.
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| Cell Mol Immunol. Oct;19(10):1117-1129. doi: 10.1038/s41423-022-00907-9. Epub 2022 Aug 19. 2022
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| 2 | IL5
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| Interleukin-5-induced eosinophil population improves cardiac function after myocardial infarction
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| Xu JY, Xiong YY, Tang RJ, Jiang WY, Ning Y, Gong ZT, Huang PS, Chen GH, Xu J, Wu CX, Hu MJ, Xu J, Xu Y, Huang CR, Jin C, Lu XT, Qian HY, Li XD, Yang YJ.
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| Cardiovasc Res. Jul 20;118(9):2165-2178. doi: 10.1093/cvr/cvab237 2022
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| 3 | IL5, IL6, IL8
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| An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis
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| Liu Y, Chen D, Hou J, Li H, Cao D, Guo M, Ling Y, Gao M, Zhou Y, Wan Y, Zhu Z.
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| Cytokine. Feb;138:155365. doi: 10.1016/j.cyto.2020.155365. Epub 2020 Nov 9. 2021
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| 4 | IL5
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| Interleukin-5 in the Pathophysiology of Severe Asthma
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| Pelaia C, Paoletti G, Puggioni F, Racca F, Pelaia G, Canonica GW, Heffler E.
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| Front Physiol. Dec 17;10:1514. doi: 10.3389/fphys.2019.01514. 2019
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| 5 | IL5, STAT5
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| Interleukin-5 suppresses Vascular Endothelial Growth Factor-induced angiogenesis through STAT5 signaling
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| Bucher F, Lee J, Shin S, Kim MS, Oh YS, Ha S, Zhang H, Yea K.
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| Cytokine Oct;110:397-403. doi: 10.1016/j.cyto.2018.06.021. Epub 2018 Jun 18 2018
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| 6 | IL5
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| Dysregulation of interleukin 5 expression in familial eosinophilia.
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| Prakash Babu S, Chen YK, Bonne-Annee S, Yang J, Maric I, Myers TG, Nutman TB, Klion AD.
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| Allergy. Sep;72(9):1338-1345. doi: 10.1111/all.13146. Epub 2017 Apr 18. 2017
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| 7 | IL5
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| The past, present, and future of monoclonal antibodies to IL-5 and eosinophilic asthma: a review
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| Patterson MF, Borish L, Kennedy JL.
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| J Asthma Allergy. Nov 3;8:125-34. doi: 10.2147/JAA.S74178. 2015
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| 8 | IL4, IL5
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| IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation
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| Fulkerson PC, Schollaert KL, Bouffi C, Rothenberg ME.
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| J Immunol. Oct 15;193(8):4043-52. doi: 10.4049/jimmunol.1400732. Epub 2014 Sep 17. 2014
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| 9 | IL5
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| Inhibition of interleukin-5 for the treatment of eosinophilic diseases.
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| Corren J.
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| Discov Med. Apr;13(71):305-12. 2012
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| 10 | IL5, NR1H3
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| Activation of liver X receptor induces macrophage interleukin-5 expression.
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| Chen Y, Duan Y, Kang Y, Yang X, Jiang M, Zhang L, Li G, Yin Z, Hu W, Dong P, Li X, Hajjar DP, Han J.
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| J Biol Chem. Dec 21;287(52):43340-50. doi: 10.1074/jbc.M112.403394. Epub 2012 Nov 13. 2012
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| 11 | IL5
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| Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion
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| Stathopoulos GT, Sherrill TP, Karabela SP, Goleniewska K, Kalomenidis I, Roussos C, Fingleton B, Yull FE, Peebles RS Jr, Blackwell TS.
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| Am J Respir Crit Care Med. Nov 15;182(10):1273-81. doi: 10.1164/rccm.201001-0001OC. Epub 2010 Jul 1. 2010
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| 12 | IL5, IL5RA
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| IL-5 and IL-5 receptor alpha polymorphisms are associated with atopic dermatitis in Koreans.
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| Namkung JH, Lee JE, Kim E, Cho HJ, Kim S, Shin ES, Cho EY, Yang JM.
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| Allergy 62(8):934-42. 2007
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| 13 | IL5, IL5RA
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| Decreased expression of membrane IL-5 receptor alpha on human eosinophils: II. IL-5 down-modulates its receptor via a proteinase-mediated process.
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| Liu LY, Sedgwick JB, Bates ME, Vrtis RF, Gern JE, Kita H, Jarjour NN, Busse WW, Kelly EA.
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| J Immunol 169(11):6459-66. 2002
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| 14 | IL13, IL4, IL5
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| Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons.
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| Loots GG, Locksley RM, Blankespoor CM, Wang ZE, Miller W, Rubin EM, Frazer KA.
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| Science 288(5463):136-40. 2000
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| 15 | IL5
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| Mutation analysis of interleukin-5 in an asthmatic cohort.
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| Pereira E, Goldblatt J, Rye P, Sanderson C, Le Souef P.
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| Hum Mutat 11(1):51-4. 1998
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| 16 | IL5
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| Characterisation of inducible DNase I hypersensitive sites flanking the human interleukin-5 gene.
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| Valentine JE, Sewell WA.
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| Biochim Biophys Acta 1442 : 218-229. 1998
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| 17 | AFF4, ARAP3, CCNL1, FACLL, IL5, IRF1, KIF3A, P4HA2, PDLIM4, RAD50, SEPTIN8, SHROOM1
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| Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.
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| Frazer KA, Ueda Y, Zhu Y, Gifford VR, Garofalo MR, Mohandas N, Martin CH, Palazzolo MJ, Cheng JF, Rubin EM.
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| Genome Res 7 : 495-512. 1997
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| 18 | IL4, IL5
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| Characterization of yeast artificial chromosomes containing interleukin genes on human chromosome 5.
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| Stock W, et al.
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| Cytogenet Cell Genet 61 : 263-265. 1992
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| 19 | IL5, CSF2
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| Expression of interleukin-5 and granulocyte-macrophage colony-stimulating factor in human peripheral blood mononuclear cells after activation with phorbol myristate acetate.
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| Staynov DZ, et al.
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| Immunology 75 : 196-201. 1992
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| 20 | IL5, IL2
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| Expression of interleukin 5 by the CD4+CD45Ro+ subset of human T cells.
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| Sewell WA, et al.
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| Growth Factors 6 : 295-302. 1992
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| 21 | IL4, IL5
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| A long-range restriction map of the interleukin-4 and interleukin-5 group on chromosome 5.
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| Chandrasekharappa SC, et al.
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| Genomics 6 : 94-99. 1990
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| 22 | IL5
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| Chromosomal mapping of the mouse IL-4 and human IL-5 genes.
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| Takahashi M, Yoshida MC, Satoh H, Hilgers J, Yaoita Y, Honjo T.
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| Genomics 4 : 47-52. 1989
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| 23 | IL4, IL5
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| Interleukin-4 and interleukin-5 map to human chromosome-5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).
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| Le Beau MM, et al.
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| Blood 73 : 647-650. 1989
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| 24 | IL5
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| Interleukin-5 is at 5q31 and is deleted in the 5q-syndrome.
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| Sutherland GR, et al.
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| Blood 71 : 1150-1152. 1988
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