| 1 | IL4, IL4R
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| IL-4 and IL-4 receptor expression is dispensable for the development and function of natural killer T cells.
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| Sharma A, Berga-Bolanos R, Sultana DA, Sen JM.
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| PLoS One 8(8):e71872. doi: 10.1371/journal.pone.0071872. eCollection 2013.
2013
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| 2 | IL4, IL4R
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| Eosinophils secrete IL-4 to facilitate liver regeneration.
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| Goh YP, Henderson NC, Heredia JE, Red Eagle A, Odegaard JI, Lehwald N, Nguyen KD, Sheppard D, Mukundan L, Locksley RM, Chawla A.
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| Proc Natl Acad Sci U S A 110(24):9914-9. doi: 10.1073/pnas.1304046110. Epub 2013 May 28.
2013
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| 3 | IL13, IL4R
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| Polymorphisms in the IL-13 and IL-4R genes are associated with the development of renal cell carcinoma.
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| Chu H, Wang M, Yan F, Zhong D, Shi D, Ma L, Pan X, Qin C, Yin C, Zhang Z.
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| Ann Oncol 23(8):2114-21. Epub 2012 Feb 8.
2012
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| 4 | IL4R
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| Association of IL-4 receptor gene polymorphisms with high density lipoprotein cholesterol.
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| Chang YH, Huang CN, Shiau MY.
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| Cytokine 59(2):309-12. doi: 10.1016/j.cyto.2012.04.023. Epub 2012 May 24.
2012
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| 5 | IL4R
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| Expression of interleukin-4 receptor alpha in human pleural mesothelioma is associated with poor survival and promotion of tumor inflammation.
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| Burt BM, Bader A, Winter D, Rodig SJ, Bueno R, Sugarbaker DJ.
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| Clin Cancer Res 18(6):1568-77. doi: 10.1158/1078-0432.CCR-11-1808. Epub 2012 Jan 18.
2012
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| 6 | IL4R
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| Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice.
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| Perkins C, Yanase N, Smulian G, Gildea L, Orekov T, Potter C, Brombacher F, Aronow B, Wills-Karp M, Finkelman FD.
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| J Exp Med 208(4):853-67. doi: 10.1084/jem.20100023. Epub 2011 Apr 4.
2011
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| 7 | IL13RA1, IL4R
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| Expression of IL-4/IL-13 receptors in differentiating human airway epithelial cells.
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| White SR, Martin LD, Stern R, Laxman B, Marroquin BA.
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| Am J Physiol Lung Cell Mol Physiol 299(5):L681-93. doi: 10.1152/ajplung.00422.2009. Epub 2010 Aug 20.
2010
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| 8 | IL4R
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| In vivo regulation of the allergic response by the IL-4 receptor alpha chain immunoreceptor tyrosine-based inhibitory motif.
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| Tachdjian R, Al Khatib S, Schwinglshackl A, Kim HS, Chen A, Blasioli J, Mathias C, Kim HY, Umetsu DT, Oettgen HC, Chatila TA.
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| J Allergy Clin Immunol 125(5):1128-1136.e8. doi: 10.1016/j.jaci.2010.01.054. Epub 2010 Apr 14.
2010
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| 9 | IL4R
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| Epithelial interleukin-4 receptor expression promotes colon tumor growth.
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| Koller FL, Hwang DG, Dozier EA, Fingleton B.
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| Carcinogenesis 31(6):1010-7. doi: 10.1093/carcin/bgq044. Epub 2010 Feb 22.
2010
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| 10 | IL4R
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| Association analysis of SNPs in the IL4R locus with type I diabetes.
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| Erlich HA, Lohman K, Mack SJ, Valdes AM, Julier C, Mirel D, Noble JA, Morahan GE, Rich SS; Type I Diabetes Genetics Consortium.
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| Genes Immun 10 Suppl 1:S33-41. doi: 10.1038/gene.2009.89.
2009
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| 11 | IL4R, SYK
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| IL-4R(alpha), a new member that associates with Syk kinase: implication in IL-4-induced human neutrophil functions.
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| Ennaciri J, Girard D.
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| J Immunol 183(8):5261-9. doi: 10.4049/jimmunol.0900109. Epub 2009 Sep 25. Erratum in: J Immunol. 2010 Feb 1;184(3):1654.
2009
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| 12 | IL13, IL13RA1, IL4, IL4R
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| Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
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| Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME.
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| Proc Natl Acad Sci U S A 105(20):7240-5. doi: 10.1073/pnas.0802465105. Epub 2008 May 14. 2008
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| 13 | DOCK2, IL4R
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| T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.
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| Tanaka Y, Hamano S, Gotoh K, Murata Y, Kunisaki Y, Nishikimi A, Takii R, Kawaguchi M, Inayoshi A, Masuko S, Himeno K, Sasazuki T, Fukui Y.
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| Nat Immunol 8(10):1067-75. Epub 2007 Sep 2.
2007
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| 14 | IL4R
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| Common variants within the interleukin 4 receptor alpha gene (IL4R) are associated with susceptibility to osteoarthritis.
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| Forster T, Chapman K, Loughlin J.
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| Hum Genet 114(4):391-5. Epub 2004 Jan 24. 2004
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| 15 | CSF2, IL13, IL3, IL4, IL4R, IL9, IRF1, TCF7
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| A second-generation association study of the 5q31 cytokine gene cluster and the interleukin-4 receptor in asthma.
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| Kauppi P, Lindblad-Toh K, Sevon P, Toivonen HT, Rioux JD, Villapakkam A, Laitinen LA, Hudson TJ, Kere J, Laitinen T.
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| Genomics 77(1/2):35-42. 2001
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| 16 | IL4R
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| Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations.
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| Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, Bleecker ER, Cox NJ.
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| Am J Hum Genet 66(2):517-26. 2000
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| 17 | IL4R
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| The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction.
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| Kruse S, Japha T, Tedner M, Sparholt SH, Forster J, Kuehr J, Deichmann KA.
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| Immunology 96(3):365-71. 1999
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| 18 | IL4R
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| Ile50Val variant of IL4Ralpha upregulates IgE synthesis and associates with atopic asthma.
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| Mitsuyasu H, et al.
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| Nat Genet 19 : 119-120. 1998
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| 19 | IL4R
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| Common polymorphisms in the coding part of the IL4-receptor gene.
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| Deichmann K, et al.
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| Biochem Biophys Res Commun 231 : 696-697. 1997
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| 20 | IL4R
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| The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor.
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| Hershey GK, Friedrich MF, Esswein LA, Thomas ML, Chatila TA.
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| N Engl J Med 337(24):1720-5. 1997
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| 21 | IL4R
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| The interleukin-4 receptor gene (IL4R) maps to 16p11.2-16p12.1 in human and to the distal region of mouse chromosome 7.
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| Pritchard MA, et al.
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| Genomics 10 : 801-806. 1991
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| 22 | IL4R
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| Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
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| Idzerda RL, March CJ, Mosley B, Lyman SD, Vanden Bos T, Gimpel SD, Din WS, Grabstein KH, Widmer MB, Park LS, et al.
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| J Exp Med 171(3):861-73. 1990
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