| 1 | IL3
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| IL-3 promotes osteoblast differentiation and bone formation in human mesenchymal stem cells.
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| Barhanpurkar AP, Gupta N, Srivastava RK, Tomar GB, Naik SP, Joshi SR, Pote ST, Mishra GC, Wani MR.
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| Biochem Biophys Res Commun 418(4):669-75. doi: 10.1016/j.bbrc.2012.01.074. Epub 2012 Jan 24.
2012
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| 2 | IL3
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| Complex interactions in EML cell stimulation by stem cell factor and IL-3.
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| Ye ZJ, Gulcicek E, Stone K, Lam T, Schulz V, Weissman SM.
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| Proc Natl Acad Sci U S A 108(12):4882-7. Epub 2011 Mar 7.
2011
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| 3 | IL3, XBP1
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| Anti-apoptotic function of Xbp1 as an IL-3 signaling molecule in hematopoietic cells.
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| Kurata M, Yamazaki Y, Kanno Y, Ishibashi S, Takahara T, Kitagawa M, Nakamura T.
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| Cell Death Dis 2:e118.
2011
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| 4 | IL3
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| IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks.
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| Meyer CG, Calixto Fernandes MH, Intemann CD, Kreuels B, Kobbe R, Kreuzberg C, Ayim M, Ruether A, Loag W, Ehmen C, Adjei S, Adjei O, Horstmann RD, May J.
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| Hum Mol Genet 20(6):1173-81. Epub 2011 Jan 10.
2011
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| 5 | IL3, RHOH
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| The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression.
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| Gündogdu MS, Liu H, Metzdorf D, Hildebrand D, Aigner M, Aktories K, Heeg K, Kubatzky KF.
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| Mol Cancer 9:225.
2010
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| 6 | IL3
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| Irreversible inhibition of RANK expression as a possible mechanism for IL-3 inhibition of RANKL-induced osteoclastogenesis.
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| Khapli SM, Tomar GB, Barhanpurkar AP, Gupta N, Yogesha SD, Pote ST, Wani MR.
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| Biochem Biophys Res Commun 399(4):688-93. Epub 2010 Aug 5.
2010
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| 7 | IL3
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| The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development.
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| Mirabella F, Baxter EW, Boissinot M, James SR, Cockerill PN.
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| J Immunol 184(6):3043-54. Epub 2010 Feb 10.
2010
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| 8 | IL3
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| IL-3 and oncogenic Abl regulate the myeloblast transcriptome by altering mRNA stability.
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| Ernst J, Ghanem L, Bar-Joseph Z, McNamara M, Brown J, Steinman RA.
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| PLoS One 4(10):e7469.
2009
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| 9 | IL3
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| IL-3 inhibits TNF-alpha-induced bone resorption and prevents inflammatory arthritis.
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| Yogesha SD, Khapli SM, Srivastava RK, Mangashetti LS, Pote ST, Mishra GC, Wani MR.
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| J Immunol 182(1):361-70.
2009
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| 10 | IL3, PIM1
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| IL-3 induces a Pim1-dependent antiapoptotic pathway in primary human basophils.
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| Didichenko SA, Spiegl N, Brunner T, Dahinden CA.
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| Blood 112(10):3949-58. Epub 2008 Sep 2.
2008
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| 11 | EPO, IL3, KITLG
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| Synergistic effect of cytokines EPO, IL-3 and SCF on the proliferation, differentiation and apoptosis of erythroid progenitor cells.
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| Wang J, Tang ZY, Ka W, Sun D, Yao W, Wen Z, Chien S.
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| Clin Hemorheol Microcirc 37(4):291-9.
2007
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| 12 | IL3
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| Interleukin-3 prevents neuronal death induced by amyloid peptide.
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| Zambrano A, Otth C, Mujica L, Concha II, Maccioni RB.
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| BMC Neurosci 8:82.
2007
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| 13 | PTPN11, IL3
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| Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling.
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| Yu WM, Daino H, Chen J, Bunting KD, Qu CK.
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| J Biol Chem 281(9):5426-34. Epub 2005 Dec 21. 2006
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| 14 | IL3
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| Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to the disease.
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| Yamada R, Tanaka T, Unoki M, Nagai T, Sawada T, Ohnishi Y, Tsunoda T, Yukioka M, Maeda A, Suzuki K, Tateishi H, Ochi T, Nakamura Y, Yamamoto K.
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| Am J Hum Genet 68(3):674-85. 2001
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| 15 | CSF2, IL13, IL3, IL4, IL4R, IL9, IRF1, TCF7
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| A second-generation association study of the 5q31 cytokine gene cluster and the interleukin-4 receptor in asthma.
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| Kauppi P, Lindblad-Toh K, Sevon P, Toivonen HT, Rioux JD, Villapakkam A, Laitinen LA, Hudson TJ, Kere J, Laitinen T.
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| Genomics 77(1/2):35-42. 2001
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| 16 | AKT1, AKT2, IL3, BAD
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| Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.
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| del Peso L, et al.
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| Science 278(5338):687-9. 1997
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| 17 | IL3, IL4, IL9
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| SSC polymorphisms in interleukin genes.
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| Borish L, et al.
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| Hum Mol Genet 3 : 1710. 1994
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| 18 | IL3
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| Structural comparison and chromosomal localization of the human and mouse IL-13 genes.
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| McKenzie ANJ, et al.
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| J Immunol 150 : 5436-5444. 1993
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| 19 | ADRB2, CD14, CSF1R, FGF1, GABRA1, IL3, IL9, GABRG2
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| A radiation hybrid map of 18 growth factor , growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5.
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| Warrington JA, et al.
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| Genomics 13 : 803-808. 1992
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| 20 | CSF2, IL3
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| Linkage mapping of the human CSF2 and IL3 genes.
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| Frolova EI, et al.
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| Proc Natl Acad Sci U S A 88 : 4821-4824. 1991
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| 21 | CSF2, IL3
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| Molecular organization of the cytokine gene cluster, involving the human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5.
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| van Leeuwen BH, et al.
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| Blood 73 : 1142-1148. 1989
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| 22 | IL3
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| A BglII RFLP demonstrated for the Il-3 gene in normal human blood cells and leukemias.
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| Jaquet K, et al.
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| Nucleic Acids Res 17 : 3620. 1989
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| 23 | IL3
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| The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene.
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| Grimaldi JC, et al.
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| Blood 73 : 2081-2085. 1989
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| 24 | CSF2, IL3
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| The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5.
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| Yang YC, et al.
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| Blood 71 : 958-961. 1988
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| 25 | IL3
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| IL3 maps to human chromosome 5 and is deleted in myeloid leukemias with a del(5q).
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| Le Beau MM, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 644. 1987
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| 26 | CSF2, IL3
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| Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and multi-CSF (IL3).
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| Barlow DP, et al.
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| EMBO J 6 : 617-623. 1987
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| 27 | IL3
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| The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q.
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| Le Beau MM, et al.
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| Proc Natl Acad Sci U S A 84 : 5913-5917. 1987
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