| 1 | IL2RA
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| CD25 as an adverse prognostic factor in elderly patients with acute myeloid leukemia.
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| Fujiwara SI, Muroi K, Yamamoto C, Hatano K, Okazuka K, Sato K, Oh I, Ohmine K, Suzuki T, Ozawa K.
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| Hematology 22(6):347-353. doi: 10.1080/10245332.2016.1276240. Epub 2017 Jan 18.
2017
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| 2 | IL2RA
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| The serum concentration of soluble interleukin-2 receptor in patients with Kawasaki disease.
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| Teraura H, Kotani K, Minami T, Takeshima T, Shimooki O, Kajii E.
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| Ann Clin Biochem 54(2):209-213. doi: 10.1177/0004563216677583. Epub 2017 Jan 12. Review.
2017
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| 3 | IL2RA
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| Interleukin-2 receptor-α proximal promoter hypomethylation is associated with multiple sclerosis.
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| Field J, Fox A, Jordan MA, Baxter AG, Spelman T, Gresle M, Butzkueven H, Kilpatrick TJ, Rubio JP.
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| Genes Immun 18(2):59-66. doi: 10.1038/gene.2016.50. Epub 2017 Jan 12.
2017
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| 4 | IL2RA
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| Multiple single nucleotide polymorphisms in the first intron of the IL2RA gene affect transcription factor binding and enhancer activity.
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| Schwartz AM, Demin DE, Vorontsov IE, Kasyanov AS, Putlyaeva LV, Tatosyan KA, Kulakovskiy IV, Kuprash DV.
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| Gene 602:50-56. doi: 10.1016/j.gene.2016.11.032. Epub 2016 Nov 19.
2017
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| 5 | IL2RA
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| Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?
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| Zea AH, Stewart T, Ascani J, Tate DJ, Finkel-Jimenez B, Wilk A, Reiss K, Smoyer WE, Aviles DH.
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| PLoS One 11(7):e0157907. doi: 10.1371/journal.pone.0157907. eCollection 2016.
2016
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| 6 | IL2RA, TAGAP
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| The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells.
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| Berge T, Leikfoss IS, Brorson IS, Bos SD, Page CM, Gustavsen MW, Bjølgerud A, Holmøy T, Celius EG, Damoiseaux J, Smolders J, Harbo HF, Spurkland A.
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| Genes Immun 17(2):118-27. doi: 10.1038/gene.2015.61. Epub 2016 Jan 14.
2016
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| 7 | IL2RA
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| IL2RA is associated with persistence of rheumatoid arthritis.
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| van Steenbergen HW, van Nies JA, Ruyssen-Witrand A, Huizinga TW, Cantagrel A, Berenbaum F, van der Helm-van Mil AH.
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| Arthritis Res Ther 17:244. doi: 10.1186/s13075-015-0739-6.
2015
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| 8 | IL2RA
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| Membrane protrusion powers clathrin-independent endocytosis of interleukin-2 receptor.
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| Basquin C, Trichet M, Vihinen H, Malardé V, Lagache T, Ripoll L, Jokitalo E, Olivo-Marin JC, Gautreau A, Sauvonnet N.
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| EMBO J 34(16):2147-61. doi: 10.15252/embj.201490788. Epub 2015 Jun 29.
2015
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| 9 | IL2RA
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| Immune derangements in patients with myelofibrosis: the role of Treg, Th17, and sIL2Rα.
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| Wang JC, Sindhu H, Chen C, Kundra A, Kafeel MI, Wong C, Lichter S.
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| PLoS One 10(3):e0116723. doi: 10.1371/journal.pone.0116723. eCollection 2015.
2015
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| 10 | IL2RA
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| Expression of CD25 is a specific and relatively sensitive marker for the Philadelphia chromosome (BCR-ABL1) translocation in pediatric B acute lymphoblastic leukemia.
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| Gaikwad AS, Donohue RE, Elghetany MT, Sheehan AM, Lu XY, Gramatges MM, McClain KL, Mistretta TA, Punia JN, Moore TJ, Goltsova T, Cubbage M, Curry CV.
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| Int J Clin Exp Pathol 7(9):6225-30. eCollection 2014.
2014
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| 11 | IL2RA
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| Reduced FOXP3(+) regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms.
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| Sebode M, Peiseler M, Franke B, Schwinge D, Schoknecht T, Wortmann F, Quaas A, Petersen BS, Ellinghaus E, Baron U, Olek S, Wiegard C, Weiler-Normann C, Lohse AW, Herkel J, Schramm C.
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| J Hepatol 60(5):1010-6. doi: 10.1016/j.jhep.2013.12.027. Epub 2014 Jan 8.
2014
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| 12 | IL2RA
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| Soluble interleukin-2 receptor alpha in preclinical type 1 diabetes.
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| Krause S, Beyerlein A, Winkler C, Gavrisan A, Kayser C, Puff R, Bonifacio E, Ziegler AG, Achenbach P.
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| Acta Diabetol 51(3):517-8. doi: 10.1007/s00592-013-0512-8. Epub 2013 Sep 5. No abstract available.
2014
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| 13 | IL2RA, IMD41
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| Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity.
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| Goudy K, Aydin D, Barzaghi F, Gambineri E, Vignoli M, Ciullini Mannurita S, Doglioni C, Ponzoni M, Cicalese MP, Assanelli A, Tommasini A, Brigida I, Dellepiane RM, Martino S, Olek S, Aiuti A, Ciceri F, Roncarolo MG, Bacchetta R.
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| Clin Immunol 146(3):248-61. doi: 10.1016/j.clim.2013.01.004. Epub 2013 Jan 24.
2013
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| 14 | IL2RA
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| CpG methylation changes within the IL2RA promoter in type 1 diabetes of childhood onset.
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| Belot MP, Fradin D, Mai N, Le Fur S, Zélénika D, Kerr-Conte J, Pattou F, Lucas B, Bougnères P.
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| PLoS One 8(7):e68093. doi: 10.1371/journal.pone.0068093. Print 2013.
2013
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| 15 | IL2RA, KHDRBS1
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| Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells.
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| Fu K, Sun X, Zheng W, Wier EM, Hodgson A, Tran DQ, Richard S, Wan F.
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| Nat Commun 4:1909. doi: 10.1038/ncomms2916.
2013
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| 16 | IL2RA, PIK3CA
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| The signalling factor PI3K is a specific regulator of the clathrin-independent dynamin-dependent endocytosis of IL-2 receptors.
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| Basquin C, Malardé V, Mellor P, Anderson DH, Meas-Yedid V, Olivo-Marin JC, Dautry-Varsat A, Sauvonnet N.
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| J Cell Sci 126(Pt 5):1099-108. doi: 10.1242/jcs.110932. Epub 2013 Jan 23.
2013
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| 17 | DHPS, IL2RA
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| Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes.
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| Colvin SC, Maier B, Morris DL, Tersey SA, Mirmira RG.
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| J Biol Chem 288(51):36226-35. doi: 10.1074/jbc.M113.473942. Epub 2013 Nov 6.
2013
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| 18 | FOXP3, IL2RA
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| Forkhead transcription factor FOXP3 upregulates CD25 expression through cooperation with RelA/NF-κB.
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| Camperio C, Caristi S, Fanelli G, Soligo M, Del Porto P, Piccolella E.
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| PLoS One 7(10):e48303. doi: 10.1371/journal.pone.0048303. Epub 2012 Oct 29.
2012
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| 19 | IL2RA
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| Interleukin 2 receptor α gene polymorphism and risk of multiple sclerosis: a meta-analysis.
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| Wang LM, Zhang DM, Xu YM, Sun SL.
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| J Int Med Res 39(5):1625-35.
2011
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| 20 | IL2RA
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| Mechanics of the IL2RA gene activation revealed by modeling and atomic force microscopy.
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| Milani P, Marilley M, Sanchez-Sevilla A, Imbert J, Vaillant C, Argoul F, Egly JM, Rocca-Serra J, Arneodo A.
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| PLoS One 6(4):e18811. doi: 10.1371/journal.pone.0018811.
2011
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| 21 | IL2, IL2RA, IL2RB
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| Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.
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| Cavanillas ML, Alcina A, Núñez C, de las Heras V, Fernández-Arquero M, Bartolomé M, de la Concha EG, Fernández O, Arroyo R, Matesanz F, Urcelay E.
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| Eur J Hum Genet 18(7):794-9. Epub 2010 Feb 24.PMID: 20179739 2010
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| 22 | CLEC16A, CTLA4, IFIH1, IL2RA, INS, MODY10, PTPN2, PTPN22
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| The molecular genetics of type 1 diabetes: new genes and emerging mechanisms.
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| Ounissi-Benkalha H, Polychronakos C.
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| Trends Mol Med 14(6):268-75. Epub 2008 May 14. 2008
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| 23 | IL2RA, IL2RB, MMEL1
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| Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
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| Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium, Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J.
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| Nat Genet 40(10):1156-9. Epub 2008 Sep 14.
2008
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| 24 | IL2RA
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| The structure of interleukin-2 complexed with its alpha receptor.
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| Rickert M, Wang X, Boulanger MJ, Goriatcheva N, Garcia KC.
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| Science 308(5727):1477-80. 2005
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| 25 | IL2RA
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| Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms.
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| Vella A, Cooper JD, Lowe CE, Walker N, Nutland S, Widmer B, Jones R, Ring SM, McArdle W, Pembrey ME, Strachan DP, Dunger DB, Twells RC, Clayton DG, Todd JA.
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| Am J Hum Genet 76(5):773-9. Epub 2005 Mar 17. 2005
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| 26 | IL2RA, IMD41
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| Human IL-2 receptor alpha chain deficiency.
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| Roifman CM.
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| Pediatr Res 48(1):6-11.
2000
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| 27 | IL2RA, IMD41
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| Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor.
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| Sharfe N, et al.
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| Proc Natl Acad Sci U S A 94 : 3168-3171. 1997
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| 28 | IL2RA, IL15RA
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| Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.
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| Anderson DM, et al.
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| J Biol Chem 270 : 29862-29869. 1995
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| 29 | IL2RA
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| Taql RFLP for the IL2RA locus.
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| Cottrell S, et al.
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| Hum Mol Genet 3 : 2085. 1994
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| 30 | IL2RA
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| A BglI polymorphism for interleukin-2 receptor gene (IL2R) on chromosome 10.
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| Ardinger RH, Murray JC.
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| Nucleic Acids Res 16 : 8201. 1988
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| 31 | IL2RA
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| Localization of the gene encoding the human interleukin-2 receptor onchromosome 10.
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| Leonard WJ, et al.
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| Science 228 : 1547-1549. 1985
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| 32 | IL2RA
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| Molecular cloning of cDNA encoding human interleukin-2 receptor.
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| Nikaido T, Shimizu A, Ishida N, Sabe H, Teshigawara K, Maeda M, Uchiyama T, Yodoi J, Honjo T.
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| Nature 311(5987):631-5. 1984
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| 33 | IL2RA
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| Molecular cloning and expression of cDNAs for the human interleukin-2 receptor.
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| Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik PB, Peffer NJ, Waldmann TA, et al.
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| Nature 311(5987):626-31. 1984
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