Citations for
1IL23A, RUNX3
A role for RUNX3 in inflammation-induced expression of IL23A in gastric epithelial cells.
Hor YT, Voon DC, Koo JK, Wang H, Lau WM, Ashktorab H, Chan SL, Ito Y.
Cell Rep 8(1):50-8. doi: 10.1016/j.celrep.2014.06.003. Epub 2014 Jul 5. 2014
2IL23A
Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?
Chiricozzi A, Saraceno R, Chimenti MS, Guttman-Yassky E, Krueger JG.
Expert Opin Ther Targets 18(5):513-25. doi: 10.1517/14728222.2014.889686. Epub 2014 Feb 25. Review. 2014
3IL1A, IL1R1, IL23A, MYD88
MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling.
Chang J, Burkett PR, Borges CM, Kuchroo VK, Turka LA, Chang CH.
Proc Natl Acad Sci U S A 110(6):2270-5. doi: 10.1073/pnas.1206048110. Epub 2013 Jan 22. 2013
4IL17A, IL23A
Increased IL-23 and IL-17 expression by peripheral blood cells of patients with primary biliary cirrhosis.
Qian C, Jiang T, Zhang W, Ren C, Wang Q, Qin Q, Chen J, Deng A, Zhong R.
Cytokine 64(1):172-80. doi: 10.1016/j.cyto.2013.07.005. Epub 2013 Jul 31. 2013
5IL23A
Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23.
Haines CJ, Chen Y, Blumenschein WM, Jain R, Chang C, Joyce-Shaikh B, Porth K, Boniface K, Mattson J, Basham B, Anderton SM, McClanahan TK, Sadekova S, Cua DJ, McGeachy MJ.
Cell Rep 3(5):1378-88. doi: 10.1016/j.celrep.2013.03.035. Epub 2013 Apr 25. 2013
6IL1A, IL1B, IL23A
Autophagy regulates IL-23 secretion and innate T cell responses through effects on IL-1 secretion.
Peral de Castro C, Jones SA, Ní Cheallaigh C, Hearnden CA, Williams L, Winter J, Lavelle EC, Mills KH, Harris J.
J Immunol 189(8):4144-53. doi: 10.4049/jimmunol.1201946. Epub 2012 Sep 12. 2012
7IL23A
Evaluation of interleukin-23 plasma levels in patients with polycythemia vera and essential thrombocythemia.
Gangemi S, Allegra A, Pace E, Alonci A, Ferraro M, Petrungaro A, Saitta S, Gerace D, Russo S, Penna G, Musolino C.
Cell Immunol 278(1-2):91-4. doi: 10.1016/j.cellimm.2012.07.003. Epub 2012 Aug 1. 2012
8IL23A
Autophagy regulates IL-23 secretion and innate T cell responses through effects on IL-1 secretion.
Peral de Castro C, Jones SA, Ní Cheallaigh C, Hearnden CA, Williams L, Winter J, Lavelle EC, Mills KH, Harris J.
J Immunol 189(8):4144-53. doi: 10.4049/jimmunol.1201946. Epub 2012 Sep 12. 2012
9IL23A
IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung.
Khader SA, Guglani L, Rangel-Moreno J, Gopal R, Junecko BA, Fountain JJ, Martino C, Pearl JE, Tighe M, Lin YY, Slight S, Kolls JK, Reinhart TA, Randall TD, Cooper AM.
J Immunol 187(10):5402-7. doi: 10.4049/jimmunol.1101377. Epub 2011 Oct 14. 2011
10IL23A
Serum interleukin-23 levels in patients with ulcerative colitis.
Mohammadi M, Hayatbakhsh MM, Zahedi MJ, Jalalpour MR, Pakgohar A.
Iran J Immunol 8(3):183-8. doi: IJIv8i3A6. 2011
11IL23A
IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass.
Adamopoulos IE, Tessmer M, Chao CC, Adda S, Gorman D, Petro M, Chou CC, Pierce RH, Yao W, Lane NE, Laface D, Bowman EP.
J Immunol 187(2):951-9. doi: 10.4049/jimmunol.1003986. Epub 2011 Jun 13. 2011
12IL17A, IL23A
Interleukin-17 and interleukin-23 in patients with polymyositis and dermatomyositis.
Shen H, Xia L, Lu J, Xiao W.
Scand J Rheumatol 40(3):217-20. doi: 10.3109/03009742.2010.517215. Epub 2011 Jan 13. 2011
13IL23A
Cutting edge: A critical functional role for IL-23 in psoriasis.
Tonel G, Conrad C, Laggner U, Di Meglio P, Grys K, McClanahan TK, Blumenschein WM, Qin JZ, Xin H, Oldham E, Kastelein R, Nickoloff BJ, Nestle FO.
J Immunol 185(10):5688-91. doi: 10.4049/jimmunol.1001538. Epub 2010 Oct 18. 2010
14IL23A
Interleukin-23 drives intestinal inflammation through direct activity on T cells.
Ahern PP, Schiering C, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, Powrie F.
Immunity 33(2):279-88. doi: 10.1016/j.immuni.2010.08.010. Erratum in: Immunity. 2011 Mar 25;34(3):448. 2010
15IL23A, PPP2CA
Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A.
Chang J, Voorhees TJ, Liu Y, Zhao Y, Chang CH.
Proc Natl Acad Sci U S A 107(18):8340-5. doi: 10.1073/pnas.0914703107. Epub 2010 Apr 19. 2010
16IL17A, IL23A
Monocyte derived interleukin (IL)-23 is an important determinant of synovial IL-17A expression in rheumatoid arthritis.
Stamp LK, Easson A, Pettersson L, Highton J, Hessian PA.
J Rheumatol 36(11):2403-8. doi: 10.3899/jrheum.081304. Epub 2009 Oct 1. 2009
17IL23A
AP-1 activated by toll-like receptors regulates expression of IL-23 p19.
Liu W, Ouyang X, Yang J, Liu J, Li Q, Gu Y, Fukata M, Lin T, He JC, Abreu M, Unkeless JC, Mayer L, Xiong H.
J Biol Chem 284(36):24006-16. doi: 10.1074/jbc.M109.025528. Epub 2009 Jul 10. 2009
18IL12B, IL23A
The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12.
Lupardus PJ, Garcia KC.
J Mol Biol 382(4):931-41. doi: 10.1016/j.jmb.2008.07.051. Epub 2008 Jul 25. 2008
19IL23A
IL-23: a master regulator in Crohn disease.
Neurath MF.
Nat Med 13(1):26-8. No abstract available. 2007
20CSF2, IL1A, IL12B, IL15, IL17A, IL18, IL23A, IL6
Cytokines in the pathogenesis of rheumatoid arthritis.
McInnes IB, Schett G.
Nat Rev Immunol 7(6):429-42. Review. 2007
21IL23A
IL-23 promotes tumour incidence and growth.
Langowski JL, Zhang X, Wu L, Mattson JD, Chen T, Smith K, Basham B, McClanahan T, Kastelein RA, Oft M.
Nature 442(7101):461-5. Epub 2006 May 10. 2006
22IL23A
Interleukin-1beta and tumor necrosis factor-alpha upregulate interleukin-23 subunit p19 gene expression in human colonic subepithelial myofibroblasts.
Zhang Z, Andoh A, Yasui H, Inatomi O, Hata K, Tsujikawa T, Kitoh K, Takayanagi A, Shimizu N, Fujiyama Y.
Int J Mol Med 15(1):79-83. 2005
23IL23A
Bordetella pertussis-infected human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization and interleukin-23 expression.
Fedele G, Stefanelli P, Spensieri F, Fazio C, Mastrantonio P, Ausiello CM.
Infect Immun 73(3):1590-7. 2005
24IL23A
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria.
Verreck FA, de Boer T, Langenberg DM, Hoeve MA, Kramer M, Vaisberg E, Kastelein R, Kolk A, de Waal-Malefyt R, Ottenhoff TH.
Proc Natl Acad Sci U S A 101(13):4560-5. Epub 2004 Mar 19. 2004
25IL23A
Antitumor and antimetastatic activity of IL-23.
Lo CH, Lee SC, Wu PY, Pan WY, Su J, Cheng CW, Roffler SR, Chiang BL, Lee CN, Wu CW, Tao MH.
J Immunol 171(2):600-7. 2003
26IL23R, IL23A
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S,Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, ZurawskiS, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW.
J Immunol 168(11):5699-708. 2002
27IL23A
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA.
Immunity 13(5):715-25. 2000