Citations for
1IL1RL1, IL33
Perinatal Licensing of Thermogenesis by IL-33 and ST2.
Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla A.
Cell 166(4):841-54. doi: 10.1016/j.cell.2016.06.040. 2016
2IL1RL1
The IL33/ST2 axis in Sjogren syndrome in relation to disease activity.
Margiotta DP, Navarini L, Vadacca M, Lo Vullo M, Pignataro F, Basta F, Afeltra A.
Eur Rev Med Pharmacol Sci 20(7):1295-9. 2016
3IL1RL1, IL33
Deletion of IL-33R attenuates VEGF expression and enhances necrosis in mammary carcinoma.
Milosavljevic MZ, Jovanovic IP, Pejnovic NN, Mitrovic SL, Arsenijevic NN, Simovic Markovic BJ, Lukic ML.
Oncotarget 7(14):18106-15. doi: 10.18632/oncotarget.7635. 2016
4IL1RL1
ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice.
Rood JE, Rao S, Paessler M, Kreiger PA, Chu N, Stelekati E, Wherry EJ, Behrens EM.
Blood 127(4):426-35. doi: 10.1182/blood-2015-07-659813. 2016
5IL1RL1, IL33
Expression of interleukin-33 and its receptor ST2 in periapical granulomas and radicular cysts.
Velickovic M, Pejnovic N, Petrovic R, Mitrovic S, Jeftic I, Kanjevac T, Lukic A.
J Oral Pathol Med 45(1):70-6. doi: 10.1111/jop.12312. 2016
6IL1RL1, IL33
Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
Cohen ES, Scott IC, Majithiya JB, Rapley L, Kemp BP, England E, Rees DG, Overed-Sayer CL, Woods J, Bond NJ, Veyssier CS, Embrey KJ, Sims DA, Snaith MR, Vousden KA, Strain MD, Chan DT, Carmen S, Huntington CE, Flavell L, Xu J, Popovic B, Brightling CE, Vaughan TJ, Butler R, Lowe DC, Higazi DR, Corkill DJ, May RD, Sleeman MA, Mustelin T.
Nat Commun 6:8327. doi: 10.1038/ncomms9327. 2015
7IL1RL1, IL33
The IL-33/ST2 axis is specifically required for development of adipose tissue-resident regulatory T cells.
Hu ZQ, Zhao WH.
Cell Mol Immunol 12(5):521-4. doi: 10.1038/cmi.2015.49. No abstract available. 2015
8IL1RL1
ST2 deletion increases inflammatory bone destruction in experimentally induced periapical lesions in mice.
Velickovic M, Pejnovic N, Mitrovic S, Radosavljevic G, Jovanovic I, Kanjevac T, Jovicic N, Lukic A.
J Endod 41(3):369-75. doi: 10.1016/j.joen.2014.11.017. 2015
9IL1RL1, IL33
Role of IL-33 and its receptor in T cell-mediated autoimmune diseases.
Zhao Q, Chen G.
Biomed Res Int 2014:587376. doi: 10.1155/2014/587376. 2014
10IL1RL1, IL33
IL-33/ST2 axis promotes mast cell survival via BCLXL.
Wang JX, Kaieda S, Ameri S, Fishgal N, Dwyer D, Dellinger A, Kepley CL, Gurish MF, Nigrovic PA.
Proc Natl Acad Sci U S A 111(28):10281-6. doi: 10.1073/pnas.1404182111. 2014
11IL1RL1
The variations in the IL1RL1 gene and susceptibility to preeclampsia.
Chen P, Zhang K, Zhou B, Zhang Z, Song Y, Pu Y, Yang Y, Zhang Y, Zhou R, Wang T, Zhang L.
Immunol Invest 43(5):424-35. doi: 10.3109/08820139.2013.879173. 2014
12IL1RL1, IL33
Alzheimer's disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brain.
Xiong Z, Thangavel R, Kempuraj D, Yang E, Zaheer S, Zaheer A.
J Alzheimers Dis 40(2):297-308. doi: 10.3233/JAD-132081. 2014
13IL1RAP, IL1RL1, IL33
Structural insights into the interaction of IL-33 with its receptors.
Liu X, Hammel M, He Y, Tainer JA, Jeng US, Zhang L, Wang S, Wang X.
Proc Natl Acad Sci U S A 110(37):14918-23. doi: 10.1073/pnas.1308651110. Epub 2013 Aug 26. 2013
14IL1RL1, IL33, IL6, IL8, TMED1
The GOLD domain-containing protein TMED1 is involved in interleukin-33 signaling.
Connolly DJ, O'Neill LA, McGettrick AF.
J Biol Chem 288(8):5616-23. doi: 10.1074/jbc.M112.403899. Epub 2013 Jan 14. 2013
15IL1RL1, IL33
A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium.
Lin J, Zhang L, Zhao G, Su Z, Deng R, Pflugfelder SC, Li DQ.
PLoS One 8(4):e60963. doi: 10.1371/journal.pone.0060963. 2013
16GATA1, GATA2, IL1RL1
GATA2 is a critical transactivator for the human IL1RL1/ST2 promoter in mast cells/basophils: opposing roles for GATA2 and GATA1 in human IL1RL1/ST2 gene expression.
Baba Y, Maeda K, Yashiro T, Inage E, Kasakura K, Suzuki R, Niyonsaba F, Hara M, Tanabe A, Ogawa H, Okumura K, Ohtsuka Y, Shimizu T, Nishiyama C.
J Biol Chem 287(39):32689-96. 2012
17IL1RL1
Soluble ST2 protein inhibits LPS stimulation on monocyte-derived dendritic cells.
Nagata A, Takezako N, Tamemoto H, Ohto-Ozaki H, Ohta S, Tominaga S, Yanagisawa K.
Cell Mol Immunol 9(5):399-409. doi: 10.1038/cmi.2012.29. 2012
18IL1RL1, IL33
ST2 and IL-33 in pregnancy and pre-eclampsia.
Granne I, Southcombe JH, Snider JV, Tannetta DS, Child T, Redman CW, Sargent IL.
PLoS One 6(9):e24463. doi: 10.1371/journal.pone.0024463. 2011
19IL1RL1, IL33
Disease-associated functions of IL-33: the new kid in the IL-1 family.
Liew FY, Pitman NI, McInnes IB.
Nat Rev Immunol 10(2):103-10. Epub 2010 Jan 18. Review.PMID: 20081870 2010
20IL1RL1
Serum soluble ST2: a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction.
Weir RA, Miller AM, Murphy GE, Clements S, Steedman T, Connell JM, McInnes IB, Dargie HJ, McMurray JJ.
J Am Coll Cardiol 55(3):243-50.PMID: 20117403 2010
21IL1RL1
Soluble ST2 for predicting sudden cardiac death in patients with chronic heart failure and left ventricular systolic dysfunction.
Pascual-Figal DA, Ordoñez-Llanos J, Tornel PL, Vázquez R, Puig T, Valdés M, Cinca J, de Luna AB, Bayes-Genis A; MUSIC Investigators.
J Am Coll Cardiol 54(23):2174-9.PMID: 19942089 2009
22IL1RL1, IL33
Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling.
Seki K, Sanada S, Kudinova AY, Steinhauser ML, Handa V, Gannon J, Lee RT.
Circ Heart Fail 2(6):684-91. Epub 2009 Sep 22.PMID: 19919994 2009
23IL1RL1
ST2 and adrenomedullin in heart failure.
Kakkar R, Lee RT.
Heart Fail Clin 5(4):515-27.PMID: 19631176 2009
24IL1RL1
Characteristics of the novel interleukin family biomarker ST2 in patients with acute heart failure.
Rehman SU, Mueller T, Januzzi JL Jr.
J Am Coll Cardiol 52(18):1458-65.PMID: 19017513 2008
25IL1RL1, IL33
The IL-33/ST2 pathway: therapeutic target and novel biomarker.
Kakkar R, Lee RT.
Nat Rev Drug Discov 7(10):827-40. Review.PMID: 18827826 2008
26IL1RL1
Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis.
Shimizu M, Matsuda A, Yanagisawa K, Hirota T, Akahoshi M, Inomata N, Ebe K, Tanaka K, Sugiura H, Nakashima K, Tamari M, Takahashi N, Obara K, Enomoto T, Okayama Y, Gao PS, Huang SK, Tominaga S, Ikezawa Z, Shirakawa T.
Hum Mol Genet 14(19):2919-27. Epub 2005 Aug 23. 2005
27IL1RL1
Identification of human ST2 protein in the sera of patients with autoimmune diseases.
Kuroiwa K, Arai T, Okazaki H, Minota S, Tominaga S.
Biochem Biophys Res Commun 284(5):1104-8. 2001
28IL1RL1
Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V.
Tago K, Noda T, Hayakawa M, Iwahana H, Yanagisawa K, Yashiro T, Tominaga S.
Biochem Biophys Res Commun 285(5):1377-83. 2001
29IL1RL1, TMED1
The cloning and nucleotide sequence of human ST2L cDNA.
Li H, Tago K, Io K, Kuroiwa K, Arai T, Iwahana H, Tominaga S, Yanagisawa K.
Genomics 67(3):284-90. 2000
30IL1RL1, IL1RL2, IL18R1
Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q.
Dale M, et al.
Genomics 57(1):177-9. 1999
31IL1RL1
Assignment of the human ST2 gene to chromosome 2 at q11.2.
Tominaga S, et al.
Hum Genet 97 : 561-563. 1996
32IL1RL1
Nucleotide sequence of a complementary DNA for human ST2.
Tominaga S, et al.
Biochim Biophys Acta 1171 : 215-218. 1992