Citations for
1CCL26, CISH, IL13
CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts.
Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, Noguchi S, Urushiyama H, Hiraishi Y, Mitani A, Borok Z, Nagase T, Yamauchi Y.
Allergol Int. Jan;68(1):101-109. doi: 10.1016/j.alit.2018.08.005. Epub 2018 Sep 6 2019
2DUOX1, IL13
Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation.
Dickinson JD, Sweeter JM, Warren KJ, Ahmad IM, De Deken X, Zimmerman MC, Brody SL.
Redox Biol 14:272-284. doi: 10.1016/j.redox.2017.09.013. Epub 2017 Sep 22. 2018
3CCL26, IL13, IL4
Eotaxin-3 (CCL26) Expression in Human Pancreatic Myofibroblasts.
Fujimoto T, Imaeda H, Takahashi K, Nishida A, Shioya M, Inatomi O, Bamba S, Shiomi H, Tani M, Andoh A.
Pancreas Mar;45(3):420-4. doi: 10.1097/MPA.0000000000000480 2016
4IL13, IL13RA1, ITGAM
Mac-1 Regulates IL-13 Activity in Macrophages by Directly Interacting with IL-13Rα1.
Cao C, Zhao J, Doughty EK, Migliorini M, Strickland DK, Kann MG, Zhang L.
J Biol Chem 290(35):21642-51. doi: 10.1074/jbc.M115.645796. Epub 2015 Jul 9. 2015
5DUOX1, DUOX2, DUOXA1, DUOXA2, IL13, IL4
Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2.
Raad H, Eskalli Z, Corvilain B, Miot F, De Deken X.
Free Radic Biol Med 56:216-25. doi: 10.1016/j.freeradbiomed.2012.09.003. Epub 2012 Sep 23. 2013
6IL13, PDGFA
Oxidant signaling for interleukin-13 gene expression in lung smooth muscle cells.
Bansal G, Wong CM, Liu L, Suzuki YJ.
Free Radic Biol Med 52(9):1552-9. Epub 2012 Feb 25. 2012
7IL13, IL4, STAT1, STAT6, TYK2
IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages.
Bhattacharjee A, Shukla M, Yakubenko VP, Mulya A, Kundu S, Cathcart MK.
Free Radic Biol Med ree Radic Biol Med. 2012 Nov 1. doi:pii: S0891-5849(12)01795-9. 10.1016/j.freeradbiomed.2012.10.553. [Epub ahead of print] 2012
8IL13
IL-13 regulates Th17 secretion of IL-17A in an IL-10-dependent manner.
Newcomb DC, Boswell MG, Huckabee MM, Goleniewska K, Dulek DE, Reiss S, Lukacs NW, Kolls JK, Peebles RS Jr.
J Immunol 188(3):1027-35. doi: 10.4049/jimmunol.1102216. Epub 2011 Dec 30. 2012
9IL13, IL4R
Polymorphisms in the IL-13 and IL-4R genes are associated with the development of renal cell carcinoma.
Chu H, Wang M, Yan F, Zhong D, Shi D, Ma L, Pan X, Qin C, Yin C, Zhang Z.
Ann Oncol 23(8):2114-21. Epub 2012 Feb 8. 2012
10IL13, IL4
Interleukin-4 and interleukin-13 prime migrational responses of haemopoietic progenitor cells to stromal cell-derived factor-1α.
Punia N, Smith S, Thomson JV, Irshad A, Nair P, Sehmi R.
Clin Exp Allergy 42(2):255-64. doi: 10.1111/j.1365-2222.2011.03889.x. Epub 2011 Oct 13. 2012
11HCK, IL13, SRC
Hck is a key regulator of gene expression in alternatively activated human monocytes.
Bhattacharjee A, Pal S, Feldman GM, Cathcart MK.
J Biol Chem 286(42):36709-23. doi: 10.1074/jbc.M111.291492. Epub 2011 Aug 30. 2011
12CCL26, CREB1, IL13
Epigenetic regulation of the IL-13-induced human eotaxin-3 gene by CREB-binding protein-mediated histone 3 acetylation.
Lim EJ, Lu TX, Blanchard C, Rothenberg ME.
J Biol Chem 286(15):13193-204. Epub 2011 Feb 16. 2011
13CFTR, IL13, IL13RA1
Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.
Wu D, Ahrens R, Osterfeld H, Noah TK, Groschwitz K, Foster PS, Steinbrecher KA, Rothenberg ME, Shroyer NF, Matthaei KI, Finkelman FD, Hogan SP.
J Biol Chem 286(15):13357-69. Epub 2011 Feb 8. 2011
14CCL5, IL13
Induction of IL-13 production and upregulated expression of protease activated receptor-1 by RANTES in a mast cell line.
Zhang H, Yang H, Ma W, He S.
Cytokine 53(2):231-8. Epub 2010 Nov 11. 2011
15IL13, IL13RA 1
Human TH17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production.
Newcomb DC, Boswell MG, Zhou W, Huckabee MM, Goleniewska K, Sevin CM, Hershey GK, Kolls JK, Peebles RS Jr.
J Allergy Clin Immunol 127(4):1006-13.e1-4. doi: 10.1016/j.jaci.2010.11.043. Epub 2011 Jan 13. 2011
16DUOX1, IL13, IL4
Dual oxidase 1 induced by Th2 cytokines promotes STAT6 phosphorylation via oxidative inactivation of protein tyrosine phosphatase 1B in human epidermal keratinocytes.
Hirakawa S, Saito R, Ohara H, Okuyama R, Aiba S.
J Immunol 186(8):4762-70. doi: 10.4049/jimmunol.1000791. Epub 2011 Mar 16. 2011
17IL10, IL13
Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus.
Zhao M, Tang J, Gao F, Wu X, Liang Y, Yin H, Lu Q.
J Biomed Biotechnol 2010:931018. Epub 2010 Jun 2. 2010
18IL13
IL-13 downregulates PPAR-gamma/heme oxygenase-1 via ER stress-stimulated calpain activation: aggravation of activated microglia death.
Liu SH, Yang CN, Pan HC, Sung YJ, Liao KK, Chen WB, Lin WZ, Sheu ML.
Cell Mol Life Sci 67(9):1465-76. Epub 2010 Mar 10. 2010
19CLCA1, IL13, IL4, IL9
Effect of Th2 type cytokines on hCLCA1 and mucus expression in cystic fibrosis airways.
Hauber HP, Lavigne F, Hung HL, Levitt RC, Hamid Q.
J Cyst Fibros 9(4):277-9. doi: 10.1016/j.jcf.2010.05.002. Epub 2010 Jun 9. 2010
20CCL26, CCR3, CX3CL1, CX3CR1, IL13, IL4
Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.
Nakayama T, Watanabe Y, Oiso N, Higuchi T, Shigeta A, Mizuguchi N, Katou F, Hashimoto K, Kawada A, Yoshie O.
J Immunol. Dec 1;185(11):6472-9. doi: 10.4049/jimmunol.0904126. Epub 2010 Oct 25 2010
21IL13
IL-13-induced oxidative stress via microglial NADPH oxidase contributes to death of hippocampal neurons in vivo.
Park KW, Baik HH, Jin BK.
J Immunol 183(7):4666-74. Epub 2009 Sep 14. 2009
22IL13
Interleukin-13 and its receptors in idiopathic interstitial pneumonia: clinical implications for lung function.
Park SW, Ahn MH, Jang HK, Jang AS, Kim DJ, Koh ES, Park JS, Uh ST, Kim YH, Park JS, Paik SH, Shin HK, Youm W, Park CS.
J Korean Med Sci 24(4):614-20. Epub 2009 Jul 29. 2009
23IL13
IL-13 induces translocation of NF-kappaB in cultured human bronchial smooth muscle cells.
Goto K, Chiba Y, Misawa M.
Cytokine 46(1):96-9. Epub 2009 Feb 23. 2009
24IL13, IL9
Interleukin-9 and -13 inhibit spontaneous and corticosteroid induced apoptosis of normal airway epithelial cells.
Singhera GK, MacRedmond R, Dorscheid DR.
Exp Lung Res 34(9):579-98. 2008
25IL13, IL13RA1, IL4, IL4R
Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME.
Proc Natl Acad Sci U S A 105(20):7240-5. doi: 10.1073/pnas.0802465105. Epub 2008 May 14. 2008
26IL13
The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture.
Webster RB, Rodriguez Y, Klimecki WT, Vercelli D.
J Biol Chem 282(1):700-9. Epub 2006 Nov 6. 2007
27IL13
IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.
Keane MP, Gomperts BN, Weigt S, Xue YY, Burdick MD, Nakamura H, Zisman DA, Ardehali A, Saggar R, Lynch JP 3rd, Hogaboam C, Kunkel SL, Lukacs NW, Ross DJ, Grusby MJ, Strieter RM, Belperio JA.
J Immunol 178(1):511-9. 2007
28IL4, IL13
Inhibition of matrix metalloproteinase-3 synthesis in human conjunctival fibroblasts by interleukin-4 or interleukin-13.
Fukuda K, Fujitsu Y, Kumagai N, Nishida T.
Invest Ophthalmol Vis Sci 47(7):2857-64. 2006
29IL13, IL13RA2
Characterization of the interaction between interleukin-13 and interleukin-13 receptors.
Arima K, Sato K, Tanaka G, Kanaji S, Terada T, Honjo E, Kuroki R, Matsuo Y, Izuhara K.
J Biol Chem 280(26):24915-22. Epub 2005 May 3. 2005
30STAT6, GATA3, KIF3A, IL4, IL13, RAD50
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.
Lee DU, Rao A.
Proc Natl Acad Sci U S A 101(45):16010-5. Epub 2004 Oct 26. 2004
31IL13
Eosinophils express functional IL-13 in eosinophilic inflammatory diseases.
Schmid-Grendelmeier P, Altznauer F, Fischer B, Bizer C, Straumann A, Menz G, Blaser K, Wuthrich B, Simon HU.
J Immunol 169(2):1021-7. 2002
32CSF2, IL13, IL3, IL4, IL4R, IL9, IRF1, TCF7
A second-generation association study of the 5q31 cytokine gene cluster and the interleukin-4 receptor in asthma.
Kauppi P, Lindblad-Toh K, Sevon P, Toivonen HT, Rioux JD, Villapakkam A, Laitinen LA, Hudson TJ, Kere J, Laitinen T.
Genomics 77(1/2):35-42. 2001
33APY11, APY5, IL13
Major genes regulating total serum immunoglobulin E levels in families with asthma.
Xu J, Postma DS, Howard TD, Koppelman GH, Zheng SL, Stine OC, Bleecker ER, Meyers DA.
Am J Hum Genet 67(5):1163-73. 2000
34IL13, IL4, IL5
Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons.
Loots GG, Locksley RM, Blankespoor CM, Wang ZE, Miller W, Rubin EM, Frazer KA.
Science 288(5463):136-40. 2000
35APY10, IL4, IL13
Requirement for IL-13 independently of IL-4 in experimental asthma.
Grunig G, et al.
Science 282(5397):2261-3. 1998
36APY10, IL4, IL13
Interleukin-13: central mediator of allergic asthma.
Wills-Karp M, et al.
Science 282(5397):2258-61. 1998
37IGES,IL13,IL4
Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations.
Marsh DG, et al.
Science 264 : 1152-1156. 1994
38IL13
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.
Minty A, et al.
Nature 362 : 248-250. 1993
39IL13
Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.
McKenzie ANJ, et al.
Proc Natl Acad Sci U S A 90 : 3735-3739. 1993
40IL13
The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes.
Morgan JG, et al.
Nucleic Acids Res 20 : 5173-5179. 1992
41IL13
173.
IL-13-induced oxidative stress via microglial NADPH oxidase contributes to death of hippocampal neurons in vivo.
Park KW, Baik HH, Jin BK ark KW, Baik HH, Jin BK.