| 1 | CCL26, CISH, IL13
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| CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts.
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| Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, Noguchi S, Urushiyama H, Hiraishi Y, Mitani A, Borok Z, Nagase T, Yamauchi Y.
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| Allergol Int. Jan;68(1):101-109. doi: 10.1016/j.alit.2018.08.005. Epub 2018 Sep 6 2019
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| 2 | DUOX1, IL13
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| Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation.
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| Dickinson JD, Sweeter JM, Warren KJ, Ahmad IM, De Deken X, Zimmerman MC, Brody SL.
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| Redox Biol 14:272-284. doi: 10.1016/j.redox.2017.09.013. Epub 2017 Sep 22.
2018
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| 3 | CCL26, IL13, IL4
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| Eotaxin-3 (CCL26) Expression in Human Pancreatic Myofibroblasts.
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| Fujimoto T, Imaeda H, Takahashi K, Nishida A, Shioya M, Inatomi O, Bamba S, Shiomi H, Tani M, Andoh A.
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| Pancreas Mar;45(3):420-4. doi: 10.1097/MPA.0000000000000480 2016
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| 4 | IL13, IL13RA1, ITGAM
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| Mac-1 Regulates IL-13 Activity in Macrophages by Directly Interacting with IL-13Rα1.
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| Cao C, Zhao J, Doughty EK, Migliorini M, Strickland DK, Kann MG, Zhang L.
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| J Biol Chem 290(35):21642-51. doi: 10.1074/jbc.M115.645796. Epub 2015 Jul 9.
2015
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| 5 | DUOX1, DUOX2, DUOXA1, DUOXA2, IL13, IL4
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| Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2.
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| Raad H, Eskalli Z, Corvilain B, Miot F, De Deken X.
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| Free Radic Biol Med 56:216-25. doi: 10.1016/j.freeradbiomed.2012.09.003. Epub 2012 Sep 23.
2013
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| 6 | IL13, PDGFA
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| Oxidant signaling for interleukin-13 gene expression in lung smooth muscle cells.
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| Bansal G, Wong CM, Liu L, Suzuki YJ.
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| Free Radic Biol Med 52(9):1552-9. Epub 2012 Feb 25. 2012
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| 7 | IL13, IL4, STAT1, STAT6, TYK2
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| IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages.
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| Bhattacharjee A, Shukla M, Yakubenko VP, Mulya A, Kundu S, Cathcart MK.
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| Free Radic Biol Med ree Radic Biol Med. 2012 Nov 1. doi:pii: S0891-5849(12)01795-9. 10.1016/j.freeradbiomed.2012.10.553. [Epub ahead of print]
2012
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| 8 | IL13
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| IL-13 regulates Th17 secretion of IL-17A in an IL-10-dependent manner.
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| Newcomb DC, Boswell MG, Huckabee MM, Goleniewska K, Dulek DE, Reiss S, Lukacs NW, Kolls JK, Peebles RS Jr.
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| J Immunol 188(3):1027-35. doi: 10.4049/jimmunol.1102216. Epub 2011 Dec 30.
2012
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| 9 | IL13, IL4R
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| Polymorphisms in the IL-13 and IL-4R genes are associated with the development of renal cell carcinoma.
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| Chu H, Wang M, Yan F, Zhong D, Shi D, Ma L, Pan X, Qin C, Yin C, Zhang Z.
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| Ann Oncol 23(8):2114-21. Epub 2012 Feb 8.
2012
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| 10 | IL13, IL4
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| Interleukin-4 and interleukin-13 prime migrational responses of haemopoietic progenitor cells to stromal cell-derived factor-1α.
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| Punia N, Smith S, Thomson JV, Irshad A, Nair P, Sehmi R.
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| Clin Exp Allergy 42(2):255-64. doi: 10.1111/j.1365-2222.2011.03889.x. Epub 2011 Oct 13.
2012
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| 11 | HCK, IL13, SRC
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| Hck is a key regulator of gene expression in alternatively activated human monocytes.
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| Bhattacharjee A, Pal S, Feldman GM, Cathcart MK.
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| J Biol Chem 286(42):36709-23. doi: 10.1074/jbc.M111.291492. Epub 2011 Aug 30.
2011
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| 12 | CCL26, CREB1, IL13
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| Epigenetic regulation of the IL-13-induced human eotaxin-3 gene by CREB-binding protein-mediated histone 3 acetylation.
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| Lim EJ, Lu TX, Blanchard C, Rothenberg ME.
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| J Biol Chem 286(15):13193-204. Epub 2011 Feb 16.
2011
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| 13 | CFTR, IL13, IL13RA1
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| Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.
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| Wu D, Ahrens R, Osterfeld H, Noah TK, Groschwitz K, Foster PS, Steinbrecher KA, Rothenberg ME, Shroyer NF, Matthaei KI, Finkelman FD, Hogan SP.
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| J Biol Chem 286(15):13357-69. Epub 2011 Feb 8.
2011
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| 14 | CCL5, IL13
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| Induction of IL-13 production and upregulated expression of protease activated receptor-1 by RANTES in a mast cell line.
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| Zhang H, Yang H, Ma W, He S.
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| Cytokine 53(2):231-8. Epub 2010 Nov 11.
2011
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| 15 | IL13, IL13RA 1
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| Human TH17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production.
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| Newcomb DC, Boswell MG, Zhou W, Huckabee MM, Goleniewska K, Sevin CM, Hershey GK, Kolls JK, Peebles RS Jr.
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| J Allergy Clin Immunol 127(4):1006-13.e1-4. doi: 10.1016/j.jaci.2010.11.043. Epub 2011 Jan 13.
2011
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| 16 | DUOX1, IL13, IL4
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| Dual oxidase 1 induced by Th2 cytokines promotes STAT6 phosphorylation via oxidative inactivation of protein tyrosine phosphatase 1B in human epidermal keratinocytes.
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| Hirakawa S, Saito R, Ohara H, Okuyama R, Aiba S.
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| J Immunol 186(8):4762-70. doi: 10.4049/jimmunol.1000791. Epub 2011 Mar 16.
2011
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| 17 | IL10, IL13
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| Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus.
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| Zhao M, Tang J, Gao F, Wu X, Liang Y, Yin H, Lu Q.
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| J Biomed Biotechnol 2010:931018. Epub 2010 Jun 2.
2010
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| 18 | IL13
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| IL-13 downregulates PPAR-gamma/heme oxygenase-1 via ER stress-stimulated calpain activation: aggravation of activated microglia death.
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| Liu SH, Yang CN, Pan HC, Sung YJ, Liao KK, Chen WB, Lin WZ, Sheu ML.
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| Cell Mol Life Sci 67(9):1465-76. Epub 2010 Mar 10.
2010
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| 19 | CLCA1, IL13, IL4, IL9
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| Effect of Th2 type cytokines on hCLCA1 and mucus expression in cystic fibrosis airways.
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| Hauber HP, Lavigne F, Hung HL, Levitt RC, Hamid Q.
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| J Cyst Fibros 9(4):277-9. doi: 10.1016/j.jcf.2010.05.002. Epub 2010 Jun 9.
2010
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| 20 | CCL26, CCR3, CX3CL1, CX3CR1, IL13, IL4
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| Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.
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| Nakayama T, Watanabe Y, Oiso N, Higuchi T, Shigeta A, Mizuguchi N, Katou F, Hashimoto K, Kawada A, Yoshie O.
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| J Immunol. Dec 1;185(11):6472-9. doi: 10.4049/jimmunol.0904126. Epub 2010 Oct 25 2010
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| 21 | IL13
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| IL-13-induced oxidative stress via microglial NADPH oxidase contributes to death of hippocampal neurons in vivo.
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| Park KW, Baik HH, Jin BK.
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| J Immunol 183(7):4666-74. Epub 2009 Sep 14.
2009
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| 22 | IL13
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| Interleukin-13 and its receptors in idiopathic interstitial pneumonia: clinical implications for lung function.
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| Park SW, Ahn MH, Jang HK, Jang AS, Kim DJ, Koh ES, Park JS, Uh ST, Kim YH, Park JS, Paik SH, Shin HK, Youm W, Park CS.
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| J Korean Med Sci 24(4):614-20. Epub 2009 Jul 29.
2009
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| 23 | IL13
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| IL-13 induces translocation of NF-kappaB in cultured human bronchial smooth muscle cells.
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| Goto K, Chiba Y, Misawa M.
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| Cytokine 46(1):96-9. Epub 2009 Feb 23.
2009
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| 24 | IL13, IL9
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| Interleukin-9 and -13 inhibit spontaneous and corticosteroid induced apoptosis of normal airway epithelial cells.
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| Singhera GK, MacRedmond R, Dorscheid DR.
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| Exp Lung Res 34(9):579-98.
2008
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| 25 | IL13, IL13RA1, IL4, IL4R
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| Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
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| Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME.
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| Proc Natl Acad Sci U S A 105(20):7240-5. doi: 10.1073/pnas.0802465105. Epub 2008 May 14. 2008
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| 26 | IL13
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| The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture.
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| Webster RB, Rodriguez Y, Klimecki WT, Vercelli D.
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| J Biol Chem 282(1):700-9. Epub 2006 Nov 6. 2007
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| 27 | IL13
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| IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.
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| Keane MP, Gomperts BN, Weigt S, Xue YY, Burdick MD, Nakamura H, Zisman DA, Ardehali A, Saggar R, Lynch JP 3rd, Hogaboam C, Kunkel SL, Lukacs NW, Ross DJ, Grusby MJ, Strieter RM, Belperio JA.
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| J Immunol 178(1):511-9. 2007
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| 28 | IL4, IL13
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| Inhibition of matrix metalloproteinase-3 synthesis in human conjunctival fibroblasts by interleukin-4 or interleukin-13.
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| Fukuda K, Fujitsu Y, Kumagai N, Nishida T.
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| Invest Ophthalmol Vis Sci 47(7):2857-64. 2006
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| 29 | IL13, IL13RA2
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| Characterization of the interaction between interleukin-13 and interleukin-13 receptors.
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| Arima K, Sato K, Tanaka G, Kanaji S, Terada T, Honjo E, Kuroki R, Matsuo Y, Izuhara K.
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| J Biol Chem 280(26):24915-22. Epub 2005 May 3. 2005
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| 30 | STAT6, GATA3, KIF3A, IL4, IL13, RAD50
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| Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.
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| Lee DU, Rao A.
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| Proc Natl Acad Sci U S A 101(45):16010-5. Epub 2004 Oct 26. 2004
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| 31 | IL13
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| Eosinophils express functional IL-13 in eosinophilic inflammatory diseases.
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| Schmid-Grendelmeier P, Altznauer F, Fischer B, Bizer C, Straumann A, Menz G, Blaser K, Wuthrich B, Simon HU.
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| J Immunol 169(2):1021-7. 2002
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| 32 | CSF2, IL13, IL3, IL4, IL4R, IL9, IRF1, TCF7
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| A second-generation association study of the 5q31 cytokine gene cluster and the interleukin-4 receptor in asthma.
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| Kauppi P, Lindblad-Toh K, Sevon P, Toivonen HT, Rioux JD, Villapakkam A, Laitinen LA, Hudson TJ, Kere J, Laitinen T.
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| Genomics 77(1/2):35-42. 2001
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| 33 | APY11, APY5, IL13
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| Major genes regulating total serum immunoglobulin E levels in families with asthma.
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| Xu J, Postma DS, Howard TD, Koppelman GH, Zheng SL, Stine OC, Bleecker ER, Meyers DA.
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| Am J Hum Genet 67(5):1163-73. 2000
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| 34 | IL13, IL4, IL5
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| Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons.
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| Loots GG, Locksley RM, Blankespoor CM, Wang ZE, Miller W, Rubin EM, Frazer KA.
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| Science 288(5463):136-40. 2000
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| 35 | APY10, IL4, IL13
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| Requirement for IL-13 independently of IL-4 in experimental asthma.
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| Grunig G, et al.
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| Science 282(5397):2261-3. 1998
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| 36 | APY10, IL4, IL13
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| Interleukin-13: central mediator of allergic asthma.
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| Wills-Karp M, et al.
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| Science 282(5397):2258-61. 1998
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| 37 | IGES,IL13,IL4
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| Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations.
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| Marsh DG, et al.
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| Science 264 : 1152-1156. 1994
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| 38 | IL13
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| Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.
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| Minty A, et al.
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| Nature 362 : 248-250. 1993
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| 39 | IL13
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| Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.
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| McKenzie ANJ, et al.
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| Proc Natl Acad Sci U S A 90 : 3735-3739. 1993
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| 40 | IL13
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| The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes.
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| Morgan JG, et al.
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| Nucleic Acids Res 20 : 5173-5179. 1992
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| 41 | IL13
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| 173.
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| IL-13-induced oxidative stress via microglial NADPH oxidase contributes to death of hippocampal neurons in vivo.
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| Park KW, Baik HH, Jin BK ark KW, Baik HH, Jin BK.
|