| 1 | IL10, IL12A, MAP2K1, TLR4
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| MEK1 dependent and independent ERK activation regulates IL-10 and IL-12 production in bone marrow derived macrophages.
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| Bouhamdan M, Bauerfeld C, Talreja J, Beuret L, Charron J, Samavati L.
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| Cell Signal 27(10):2068-76. doi: 10.1016/j.cellsig.2015.07.015. Epub 2015 Jul 21.
2015
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| 2 | IL12A, IL12B
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| The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production.
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| Jalah R, Rosati M, Ganneru B, Pilkington GR, Valentin A, Kulkarni V, Bergamaschi C, Chowdhury B, Zhang GM, Beach RK, Alicea C, Broderick KE, Sardesai NY, Pavlakis GN, Felber BK.
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| J Biol Chem 288(9):6763-76. doi: 10.1074/jbc.M112.436675. Epub 2013 Jan 7.
2013
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| 3 | DDR2, IL12A
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| Induction of IL-12 production by the activation of discoidin domain receptor 2 via NF-κB and JNK pathway.
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| Poudel B, Ki HH, Lee YM, Kim DK.
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| Biochem Biophys Res Commun 434(3):584-8. doi: 10.1016/j.bbrc.2013.03.118. Epub 2013 Apr 10. 2013
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| 4 | IL12A, IL12B, SIRT1
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| Sirtuin 1 is a key regulator of the interleukin-12 p70/interleukin-23 balance in human dendritic cells.
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| Alvarez Y, Rodríguez M, Municio C, Hugo E, Alonso S, Ibarrola N, Fernández N, Crespo MS.
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| J Biol Chem 287(42):35689-701. doi: 10.1074/jbc.M112.391839. Epub 2012 Aug 14.
2012
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| 5 | IL12A, IRF5, SPIB, TNPO3
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| Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis.
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| Liu X, Invernizzi P, Lu Y, Kosoy R, Lu Y, Bianchi I, Podda M, Xu C, Xie G, Macciardi F, Selmi C, Lupoli S, Shigeta R, Ransom M, Lleo A, Lee AT, Mason AL, Myers RP, Peltekian KM, Ghent CN, Bernuzzi F, Zuin M, Rosina F, Borghesio E, Floreani A, Lazzari R, Niro G, Andriulli A, Muratori L, Muratori P, Almasio PL, Andreone P, Margotti M, Brunetto M, Coco B, Alvaro D, Bragazzi MC, Marra F, Pisano A, Rigamonti C, Colombo M, Marzioni M, Benedetti A, Fabris L, Strazzabosco M, Portincasa P, Palmieri VO, Tiribelli C, Croce L, Bruno S, Rossi S, Vinci M, Prisco C, Mattalia A, Toniutto P, Picciotto A, Galli A, Ferrari C, Colombo S, Casella G, Morini L, Caporaso N, Colli A, Spinzi G, Montanari R, Gregersen PK, Heathcote EJ, Hirschfield GM, Siminovitch KA, Amos CI, Gershwin ME, Seldin MF.
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| Nat Genet 42(8):658-60. Epub 2010 Jul 18.PMID: 20639880 2010
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| 6 | IL12A, KLRC1
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| IL-12-dependent inducible expression of the CD94/NKG2A inhibitory receptor regulates CD94/NKG2C+ NK cell function.
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| Sáez-Borderías A, Romo N, Magri G, Gumá M, Angulo A, López-Botet M.
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| J Immunol 182(2):829-36.PMID: 19124726 2009
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| 7 | IL12A, IL18
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| Expression and significance of intratumoral interleukin-12 and interleukin-18 in human gastric carcinoma.
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| Ye ZB, Ma T, Li H, Jin XL, Xu HM.
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| World J Gastroenterol 13(11):1747-51. 2007
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| 8 | IL12A
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| Dysregulated expression of interleukin-23 and interleukin-12 subunits in systemic lupus erythematosus patients.
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| Huang X, Hua J, Shen N, Chen S.
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| Mod Rheumatol 17(3):220-3. Epub 2007 Jun 20. 2007
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| 9 | IL12A, IL12B
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| Requirement for both IL-12 and IFN-gamma signaling pathways in optimal IFN-gamma production by human T cells.
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| Losana G, Rigamonti L, Borghi I, Assenzio B, Ariotti S, Jouanguy E, Altare F, Forni G, Casanova JL, Novelli F.
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| Eur J Immunol 32(3):693-700. 2002
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| 10 | IL12A
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| Novel amplification unit at chromosome 3q25-q27 in human prostate cancer.
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| Sattler HP, Lensch R, Rohde V, Zimmer E, Meese E, Bonkhoff H, Retz M, Zwergel T, Bex A, Stoeckle M, Wullich B.
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| Prostate 45(3):207-15. 2000
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| 11 | IL12A
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| Regional mapping of genes on chromosome 3. (abstr)
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| Naylor SL, et al.
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| Cytogenet Cell Genet 65 : 43. 1994
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| 12 | IL12A, IL12B
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| Assignment of genes encoding a unique cytokine (IL12) composed of two unrelated subunits to chromosomes 3 and 5.
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| Sieburth D, et al.
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| Genomics 14 : 59-62. 1992
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