1 | BCL6, IKZF1, IKZF3, STAT3
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| Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells.
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| Read KA, Powell MD, Baker CE, Sreekumar BK, Ringel-Scaia VM, Bachus H, Martin RE, Cooley ID, Allen IC, Ballesteros-Tato A, Oestreich KJ.
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| J Immunol 199(7):2377-2387. doi: 10.4049/jimmunol.1700106. Epub 2017 Aug 28.
2017
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2 | IKZF3, IRF8, TMEM39A, ZPBP2
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| Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study.
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| Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, Adler AJ, Li H, Rasmussen A, Williams AH, Ziegler J, Comeau ME, Marion M, Wakeland BE, Liang C, Ramos PS, Grundahl KM, Gallant CJ; Marta E.
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| Am J Hum Genet 90(4):648-60. Epub 2012 Mar 29.
2012
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3 | IKZF3
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| Aiolos promotes TH17 differentiation by directly silencing Il2 expression.
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| Quintana FJ, Jin H, Burns EJ, Nadeau M, Yeste A, Kumar D, Rangachari M, Zhu C, Xiao S, Seavitt J, Georgopoulos K, Kuchroo VK.
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| Nat Immunol 13(8):770-7. doi: 10.1038/ni.2363.
2012
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4 | IKZF3
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| Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications.
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| Billot K, Soeur J, Chereau F, Arrouss I, Merle-Béral H, Huang ME, Mazier D, Baud V, Rebollo A.
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| Blood 117(6):1917-27. Epub 2010 Dec 7.
2011
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5 | IKZF1, IKZF2, IKZF3
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| Ikaros in immune receptor signaling, lymphocyte differentiation, and function.
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| Merkenschlager M.
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| FEBS Lett 584(24):4910-4. Epub 2010 Oct 2. Review.
2010
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6 | IKZF1, IKZF3
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| Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression.
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| Ma S, Pathak S, Mandal M, Trinh L, Clark MR, Lu R.
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| Mol Cell Biol 30(17):4149-58. Epub 2010 Jun 21.
2010
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7 | IKZF3
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| Differential aiolos expression in human hematopoietic subpopulations.
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| Billot K, Parizot C, Arrouss I, Mazier D, Debre P, Rogner UC, Rebollo A.
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| Leuk Res 34(3):289-93. Epub 2009 Jun 21.
2010
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8 | IKZF3
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| The Aiolos transcription factor is up-regulated in chronic lymphocytic leukemia.
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| Duhamel M, Arrouss I, Merle-Bral H, Rebollo A.
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| Blood 111(6):3225-8. Epub 2008 Jan 9. 2008
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9 | IKZF3, POU2AF1
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| Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.
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| Karnowski A, Cao C, Matthias G, Carotta S, Corcoran LM, Martensson IL, Skok JA, Matthias P.
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| PLoS One 3(10):e3568. Epub 2008 Oct 30.
2008
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10 | IKZF1, IKZF2, IKZF3, IKZF4, IKZF5
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| Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms.
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| Ronni T, Payne KJ, Ho S, Bradley MN, Dorsam G, Dovat S.
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| J Biol Chem 282(4):2538-47. Epub 2006 Nov 29. 2007
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11 | IKZF1, IKZF3
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| Critical function of Ikaros in controlling Aiolos gene expression.
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| Ghadiri A, Duhamel M, Fleischer A, Reimann A, Dessauge F, Rebollo A.
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| FEBS Lett 581(8):1605-1616. Epub 2007 Mar 20. 2007
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12 | EBF1,IKZF1,IKZF3,LEF1,PAX5,TCF3
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| Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
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| Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR.
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| Nature 446(7137):758-64. 2007
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13 | IKZF3
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| Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene.
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| Liippo J, Nera KP, Veistinen E, Lahdesmaki A, Postila V, Kimby E, Riikonen P, Hammarstrom L, Pelkonen J, Lassila O.
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| Eur J Immunol 31(12):3469-74. 2001
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14 | IKZF4, IKZF5, IKZF1, IKZF2, IKZF3
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| Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.
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| Perdomo J, Holmes M, Chong B, Crossley M.
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| J Biol Chem 275(49):38347-54. 2000
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15 | IKZF3
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| Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning,tissue expression pattern, and chromosomal mapping.
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| Hosokawa Y, Maeda Y, Takahashi E, Suzuki M, Seto M.
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| Genomics 61(3):326-9. 1999
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