1 | FOXP3, IKZF2, SATB1
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| FoxP3, Helios, and SATB1: roles and relationships in regulatory T cells.
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| Grzanka J, Leveson-Gower D, Golab K, Wang XJ, Marek-Trzonkowska N, Krzystyniak A, Wardowska A, Mills JM, Trzonkowski P, Witkowski P.
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| Int Immunopharmacol 16(3):343-7. doi: 10.1016/j.intimp.2013.02.004. Epub 2013 Feb 18.
2013
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2 | FOXP3, IKZF2
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| Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans.
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| Himmel ME, MacDonald KG, Garcia RV, Steiner TS, Levings MK.
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| J Immunol 190(5):2001-8. doi: 10.4049/jimmunol.1201379. Epub 2013 Jan 28.
2013
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3 | IKZF2
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| Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.
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| Daley SR, Hu DY, Goodnow CC.
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| J Exp Med 210(2):269-85. doi: 10.1084/jem.20121458. Epub 2013 Jan 21.
2013
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4 | IKZF2
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| Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells.
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| Baine I, Basu S, Ames R, Sellers RS, Macian F.
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| J Immunol 190(3):1008-16. doi: 10.4049/jimmunol.1200792. Epub 2012 Dec 28.
2013
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5 | BCL11B, IKZF2
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| HELIOS-BCL11B fusion gene involvement in a t(2;14)(q34;q32) in an adult T-cell leukemia patient.
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| Fujimoto R, Ozawa T, Itoyama T, Sadamori N, Kurosawa N, Isobe M.
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| Cancer Genet 205(7-8):356-64. doi: 10.1016/j.cancergen.2012.04.006.
2012
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6 | IKZF2
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| Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons.
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| Martín-Ibáñez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martínez S, Campbell K, Vicario-Abejón C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM.
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| Stem Cells Dev 21(12):2239-51. doi: 10.1089/scd.2011.0607. Epub 2012 Jan 26.
2012
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7 | IKZF2
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| Helios expression is a marker of T cell activation and proliferation.
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| Akimova T, Beier UH, Wang L, Levine MH, Hancock WW.
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| PLoS One 6(8):e24226. doi: 10.1371/journal.pone.0024226. Epub 2011 Aug 30.
2011
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8 | IKZF1, IKZF2, IKZF3
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| Ikaros in immune receptor signaling, lymphocyte differentiation, and function.
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| Merkenschlager M.
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| FEBS Lett 584(24):4910-4. Epub 2010 Oct 2. Review.
2010
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9 | IKZF2
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| Helios deficiency has minimal impact on T cell development and function.
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| Cai Q, Dierich A, Oulad-Abdelghani M, Chan S, Kastner P.
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| J Immunol 183(4):2303-11. doi: 10.4049/jimmunol.0901407. Epub 2009 Jul 20.
2009
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10 | IKZF1, IKZF2, IKZF3, IKZF4, IKZF5
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| Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms.
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| Ronni T, Payne KJ, Ho S, Bradley MN, Dorsam G, Dovat S.
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| J Biol Chem 282(4):2538-47. Epub 2006 Nov 29. 2007
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11 | IKZF2
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| Molecular characterization of new Helios isoforms.
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| Lopez-Segura,V. and Gonzalez-Sarmiento,R.
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| Unpublished 2004
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12 | IKZF1, IKZF2
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| Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia.
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| Nakase K, Ishimaru F, Fujii K, Tabayashi T, Kozuka T, Sezaki N, Matsuo Y, Harada M.
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| Exp Hematol 30(4):313-7. 2002
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13 | IKZF4, IKZF5, IKZF1, IKZF2, IKZF3
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| Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.
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| Perdomo J, Holmes M, Chong B, Crossley M.
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| J Biol Chem 275(49):38347-54. 2000
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14 | IKZF2
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| Human Helios, an Ikaros-related zinc finger DNA binding protein: cDNA cloningand tissue expression pattern.
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| Hosokawa Y, Maeda Y, Seto M.
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| Immunogenetics 50(1-2):106-8. No abstract available. 1999
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