| 1 | IKBKG, N4BP1
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| N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization.
|
| Shi H, Sun L, Wang Y, Liu A, Zhan X, Li X, Tang M, Anderton P, Hildebrand S, Quan J, Ludwig S, Moresco EMY, Beutler B.
|
| Nat Commun. Mar 2;12(1):1379. doi: 10.1038/s41467-021-21711-5. 2021
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| 2 | IKBKG, MARCHF2
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| Negative regulation of NEMO signaling by the ubiquitin E3 ligase MARCH2
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| Chathuranga K, Kim TH, Lee H, Park JS, Kim JH, Chathuranga WAG, Ekanayaka P, Choi YJ, Lee CH, Kim CJ, Jung JU, Lee JS.
|
| EMBO J. Nov 2;39(21):e105139. doi: 10.15252/embj.2020105139. Epub 2020 Sep 16. 2020
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| 3 | IKBKG, SMC4
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| Condensin Smc4 promotes inflammatory innate immune response by epigenetically enhancing NEMO transcription.
|
| Wang Q, Wang C, Li N, Liu X, Ren W, Wang Q, Cao X.
|
| J Autoimmun Autoimmun. 2018 May 24. pii: S0896-8411(18)30164-1. doi: 10.1016/j.jaut.2018.05.004. [Epub ahead of print]
2018
|
| 4 | IKBKG, SENP1
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| SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression.
|
| Shao L, Zhou HJ, Zhang H, Qin L, Hwa J, Yun Z, Ji W, Min W.
|
| Nat Commun 6:8917. doi: 10.1038/ncomms9917.
2015
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| 5 | CHUK, IKBKB, IKBKG
|
| Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO).
|
| Zhou L, Yeo AT, Ballarano C, Weber U, Allen KN, Gilmore TD, Whitty A.
|
| Biochemistry 53(50):7929-44. doi: 10.1021/bi500920n. Epub 2014 Dec 8.
2014
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| 6 | CHUK, IKBKB, IKBKG
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| Protein engineering of the N-terminus of NEMO: structure stabilization and rescue of IKKβ binding.
|
| Guo B, Audu CO, Cochran JC, Mierke DF, Pellegrini M.
|
| Biochemistry 53(43):6776-85. doi: 10.1021/bi500861x. Epub 2014 Oct 23.
2014
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| 7 | IKBKG, NMRAL1, USP7
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| HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination.
|
| Li T, Guan J, Li S, Zhang X, Zheng X.
|
| Cell Death Dis 5:e1229. doi: 10.1038/cddis.2014.197.
2014
|
| 8 | IKBKG
|
| Duplication at Xq28 involving IKBKG is associated with progressive macrocephaly, recurrent infections, ectodermal dysplasia, benign tumors, and neuropathy.
|
| van Asbeck E, Ramalingam A, Dvorak C, Chen TJ, Morava E.
|
| Clin Dysmorphol 23(3):77-82. doi: 10.1097/MCD.0000000000000038.
2014
|
| 9 | IKBKG, IP2
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| Incontinentia pigmenti: learning disabilities are a fundamental hallmark of the disease.
|
| Pizzamiglio MR, Piccardi L, Bianchini F, Canzano L, Palermo L, Fusco F, D'Antuono G, Gelmini C, Garavelli L, Ursini MV.
|
| PLoS One 9(1):e87771. doi: 10.1371/journal.pone.0087771. eCollection 2014.
2014
|
| 10 | DUPXQ28, IKBKG, MECP2
|
| NF-κB signalling requirement for brain myelin formation is shown by genotype/MRI phenotype correlations in patients with Xq28 duplications.
|
| Philippe O, Rio M, Malan V, Van Esch H, Baujat G, Bahi-Buisson N, Valayannopoulos V, Gesny R, Bonnefont JP, Munnich A, Froyen G, Amiel J, Boddaert N, Colleaux L.
|
| Eur J Hum Genet 21(2):195-9. doi: 10.1038/ejhg.2012.140. Epub 2012 Jul 18.
2013
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| 11 | IKBKG, IP2
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| A nonsense mutation in the IKBKG gene in mares with incontinentia pigmenti.
|
| Towers RE, Murgiano L, Millar DS, Glen E, Topf A, Jagannathan V, Drögemüller C, Goodship JA, Clarke AJ, Leeb T.
|
| PLoS One 8(12):e81625. doi: 10.1371/journal.pone.0081625. eCollection 2013.
2013
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| 12 | IKBKG, USP10, ZC3H12A
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| USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO.
|
| Niu J, Shi Y, Xue J, Miao R, Huang S, Wang T, Wu J, Fu M, Wu ZH.
|
| EMBO J 32(24):3206-19. doi: 10.1038/emboj.2013.247. Epub 2013 Nov 22.
2013
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| 13 | EDAID, IKBKG
|
| Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.
|
| Ngadjeua F, Chiaravalli J, Traincard F, Raynal B, Fontan E, Agou F.
|
| J Biol Chem 288(47):33722-37. doi: 10.1074/jbc.M113.483305. Epub 2013 Oct 7.
2013
|
| 14 | IKBKG, IP2
|
| Genomic architecture at the Incontinentia Pigmenti locus favours de novo pathological alleles through different mechanisms.
|
| Fusco F, Paciolla M, Napolitano F, Pescatore A, D'Addario I, Bal E, Lioi MB, Smahi A, Miano MG, Ursini MV.
|
| Hum Mol Genet 21(6):1260-71. Epub 2011 Nov 25.
2012
|
| 15 | CHUK, IKBKB, IKBKG
|
| NEMO ensures signaling specificity of the pleiotropic IKKβ by directing its kinase activity toward IκBα.
|
| Schröfelbauer B, Polley S, Behar M, Ghosh G, Hoffmann A.
|
| Mol Cell 47(1):111-21. doi: 10.1016/j.molcel.2012.04.020. Epub 2012 May 24.
2012
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| 16 | IKBKG, NSFL1C
|
| p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO.
|
| Shibata Y, Oyama M, Kozuka-Hata H, Han X, Tanaka Y, Gohda J, Inoue J.
|
| Nat Commun 3:1061. doi: 10.1038/ncomms2068.
2012
|
| 17 | IKBKG, RIPK1
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| NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
|
| O'Donnell MA, Hase H, Legarda D, Ting AT.
|
| PLoS One 7(7):e41238. doi: 10.1371/journal.pone.0041238. Epub 2012 Jul 26.
2012
|
| 18 | IKBKG
|
| Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.
|
| Kensche T, Tokunaga F, Ikeda F, Goto E, Iwai K, Dikic I.
|
| J Biol Chem 287(28):23626-34. doi: 10.1074/jbc.M112.347195. Epub 2012 May 17.
2012
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| 19 | IKBKG, RPAP3, WDR92
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| RPAP3 enhances cytotoxicity of doxorubicin by impairing NF-kappa B pathway.
|
| Shimada K, Saeki M, Egusa H, Fukuyasu S, Yura Y, Iwai K, Kamisaki Y.
|
| Biochem Biophys Res Commun 404(4):910-4. Epub 2010 Dec 22.
2011
|
| 20 | ATM, IKBKG, RIPK1
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| NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling.
|
| Biton S, Ashkenazi A.
|
| Cell 145(1):92-103.
2011
|
| 21 | CSK, IKBKG
|
| Evidence that the kinase-truncated c-Src regulates NF-κB signaling by targeting NEMO.
|
| Dai S, Abu-Amer W, Karuppaiah K, Abu-Amer Y.
|
| J Cell Biochem 112(9):2463-70. doi: 10.1002/jcb.23170.
2011
|
| 22 | IKBKG, RELA, TRAF7
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| TRAF7 protein promotes Lys-29-linked polyubiquitination of IkappaB kinase (IKKgamma)/NF-kappaB essential modulator (NEMO) and p65/RelA protein and represses NF-kappaB activation.
|
| Zotti T, Uva A, Ferravante A, Vessichelli M, Scudiero I, Ceccarelli M, Vito P, Stilo R.
|
| J Biol Chem 286(26):22924-33. Epub 2011 Apr 25.
2011
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| 23 | IKBKG, NFKB1, SENP2
|
| NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress.
|
| Lee MH, Mabb AM, Gill GB, Yeh ET, Miyamoto S.
|
| Mol Cell 43(2):180-91. 2011
|
| 24 | EDAID, IKBKG, OLEDAID
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| New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein.
|
| Hubeau M, Ngadjeua F, Puel A, Israel L, Feinberg J, Chrabieh M, Belani K, Bodemer C, Fabre I, Plebani A, Boisson-Dupuis S, Picard C, Fischer A, Israel A, Abel L, Veron M, Casanova JL, Agou F, Bustamante J.
|
| Blood 118(4):926-35. Epub 2011 May 26. 2011
|
| 25 | FADD, IKBKG
|
| Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis.
|
| Irrinki KM, Mallilankaraman K, Thapa RJ, Chandramoorthy HC, Smith FJ, Jog NR, Gandhirajan RK, Kelsen SG, Houser SR, May MJ, Balachandran S, Madesh M.
|
| Mol Cell Biol 31(18):3745-58. Epub 2011 Jul 11.
2011
|
| 26 | IKBKG, NKX3-2
|
| Exogenous signal-independent nuclear IkappaB kinase activation triggered by Nkx3.2 enables constitutive nuclear degradation of IkappaB-alpha in chondrocytes.
|
| Yong Y, Choi SW, Choi HJ, Nam HW, Kim JA, Jeong DU, Kim DY, Kim YS, Kim DW.
|
| Mol Cell Biol 31(14):2802-16. doi: 10.1128/MCB.00253-10. Epub 2011 May 23.
2011
|
| 27 | CHUK, IKBKG, SERPINB5
|
| High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer.
|
| Jiang R, Xia Y, Li J, Deng L, Zhao L, Shi J, Wang X, Sun B.
|
| Int J Cancer 126(5):1263-74. 2010
|
| 28 | IKBKG, IP2, TRAF6
|
| Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology.
|
| Gautheron J, Pescatore A, Fusco F, Esposito E, Yamaoka S, Agou F, Ursini MV, Courtois G.
|
| Hum Mol Genet 19(16):3138-49. Epub 2010 Jun 7.PMID: 20529958 2010
|
| 29 | IKBKG, TRIM23
|
| Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense.
|
| Arimoto K, Funami K, Saeki Y, Tanaka K, Okawa K, Takeuchi O, Akira S, Murakami Y, Shimotohno K.
|
| Proc Natl Acad Sci U S A 107(36):15856-61. Epub 2010 Aug 19.PMID: 20724660 2010
|
| 30 | CLSPN, IKBKB, IKBKG, REL
|
| IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function.
|
| Kenneth NS, Mudie S, Rocha S.
|
| EMBO J 29(17):2966-78. Epub 2010 Jul 23.
2010
|
| 31 | FBXW7, IKBKG, MYC
|
| NEMO stabilizes c-Myc through direct interaction in the nucleus.
|
| Kim BY, Yang JS, Kwak SY, Zhang XK, Han YH.
|
| FEBS Lett 584(22):4524-30. Epub 2010 Oct 21.
2010
|
| 32 | IKBKG
|
| NEMO mutation as a cause of familial occurrence of Behçet's disease in female patients.
|
| Takada H, Nomura A, Ishimura M, Ichiyama M, Ohga S, Hara T.
|
| Clin Genet 78(6):575-9. doi: 10.1111/j.1399-0004.2010.01432.x.
2010
|
| 33 | IKBKG
|
| The zinc finger of NEMO is a functional ubiquitin-binding domain.
|
| Cordier F, Grubisha O, Traincard F, Véron M, Delepierre M, Agou F.
|
| J Biol Chem 284(5):2902-7. Epub 2008 Nov 25.
2009
|
| 34 | IKBKG
|
| NEMO oligomerization and its ubiquitin-binding properties.
|
| Ivins FJ, Montgomery MG, Smith SJ, Morris-Davies AC, Taylor IA, Rittinger K.
|
| Biochem J 421(2):243-51.
2009
|
| 35 | CHUK, ERCC3, IKBKG
|
| Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
|
| Hosgood HD 3rd, Zhang L, Shen M, Berndt SI, Vermeulen R, Li G, Yin S, Yeager M, Yuenger J, Rothman N, Chanock S, Smith M, Lan Q.
|
| Occup Environ Med 66(12):848-53. Epub 2009 Sep 22. 2009
|
| 36 | IKBKG, IP2
|
| Microdeletion/duplication at the Xq28 IP locus causes a de novo IKBKG/NEMO/IKKgamma exon4_10 deletion in families with Incontinentia Pigmenti.
|
| Fusco F, Paciolla M, Pescatore A, Lioi MB, Ayuso C, Faravelli F, Gentile M, Zollino M, D'Urso M, Miano MG, Ursini MV.
|
| Hum Mutat 30(9):1284-91.PMID: 19603533 2009
|
| 37 | IKBKG
|
| NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain.
|
| Laplantine E, Fontan E, Chiaravalli J, Lopez T, Lakisic G, Véron M, Agou F, Israël A.
|
| EMBO J 28(19):2885-95. Epub 2009 Sep 17.PMID: 19763089 2009
|
| 38 | IKBKG, RUSC1
|
| NESCA: a new NEMO/IKKgamma and TRAF6 interacting protein.
|
| Napolitano G, Mirra S, Monfregola J, Lavorgna A, Leonardi A, Ursini MV.
|
| J Cell Physiol 220(2):410-7. doi: 10.1002/jcp.21782.
2009
|
| 39 | BLM, RTS, IKBKG, PRO1, WRN1, WRN2
|
| NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes?
|
| Salminen A, Suuronen T, Huuskonen J, Kaarniranta K.
|
| Biochem Biophys Res Commun 367(4):715-8. Epub 2008 Jan 15. Review. 2008
|
| 40 | IKBKG, IP2, OLEDAID, EDAID
|
| Alterations of the IKBKG locus and diseases: an update and a report of 13 novel mutations.
|
| Fusco F, Pescatore A, Bal E, Ghoul A, Paciolla M, Lioi MB, D'Urso M, Rabia SH, Bodemer C, Bonnefont JP, Munnich A, Miano MG, Smahi A, Ursini MV.
|
| Hum Mutat 29(5):595-604. 2008
|
| 41 | CHUK, IKBKB, IKBKG
|
| High-affinity interaction between IKKbeta and NEMO.
|
| Lo YC, Maddineni U, Chung JY, Rich RL, Myszka DG, Wu H.
|
| Biochemistry 47(10):3109-16. Epub 2008 Feb 12.
2008
|
| 42 | ASAP1, IKBKG
|
| Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.
|
| Inoue H, Ha VL, Prekeris R, Randazzo PA.
|
| Mol Biol Cell 19(10):4224-37. Epub 2008 Aug 6.
2008
|
| 43 | EDAID, IKBKG
|
| X-linked ectodermal dysplasia with immunodeficiency caused by NEMO mutation: early recognition and diagnosis.
|
| Mancini AJ, Lawley LP, Uzel G.
|
| Arch Dermatol 144(3):342-6.PMID: 18347290 2008
|
| 44 | IKBKG
|
| IKK gamma (NEMO) is involved in the coordination of the AP-1 and NF-kappa B pathways.
|
| Shifera AS, Friedman JM, Horwitz MS.
|
| Mol Cell Biochem 310(1-2):181-90. Epub 2007 Dec 16.PMID: 18080803 2008
|
| 45 | IKBKG
|
| Structure of a NEMO/IKK-associating domain reveals architecture of the interaction site.
|
| Rushe M, Silvian L, Bixler S, Chen LL, Cheung A, Bowes S, Cuervo H, Berkowitz S, Zheng T, Guckian K, Pellegrini M, Lugovskoy A.
|
| Structure 16(5):798-808.PMID: 18462684 2008
|
| 46 | IKBKG, IMD33
|
| The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases.
|
| Al-Muhsen S, Casanova JL.
|
| J Allergy Clin Immunol 122(6):1043-51; quiz 1052-3. doi: 10.1016/j.jaci.2008.10.037. Review.
2008
|
| 47 | TRAF6, IKBKG
|
| Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.
|
| Sebban-Benin H, Pescatore A, Fusco F, Pascuale V, Gautheron J, Yamaoka S, Moncla A, Ursini MV, Courtois G.
|
| Hum Mol Genet 16(23):2805-15. Epub 2007 Aug 29. 2007
|
| 48 | IKBKG, IP2
|
| Incontinentia pigmenti in a newborn with a novel nonsense mutation in the NEMO gene.
|
| Has C, Danescu S, Volz A, Nöh F, Technau K, Bruckner-Tuderman L.
|
| Br J Dermatol 156(2):392-3. Review. No abstract available.
2007
|
| 49 | DDX58, IKBKG, MAVS
|
| The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways.
|
| Zhao T, Yang L, Sun Q, Arguello M, Ballard DW, Hiscott J, Lin R.
|
| Nat Immunol 8(6):592-600. Epub 2007 Apr 29. 2007
|
| 50 | EDAID, IKBKG
|
| Novel splicing mutation in the NEMO (IKK-gamma) gene with severe immunodeficiency and heterogeneity of X-chromosome inactivation.
|
| Orstavik KH, Kristiansen M, Knudsen GP, Storhaug K, Vege A, Eiklid K, Abrahamsen TG, Smahi A, Steen-Johnsen J.
|
| Am J Med Genet A 140(1):31-9. 2006
|
| 51 | IKBKG, IP2
|
| Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling.
|
| Nenci A, Huth M, Funteh A, Schmidt-Supprian M, Bloch W, Metzger D, Chambon P, Rajewsky K, Krieg T, Haase I, Pasparakis M.
|
| Hum Mol Genet 15(4):531-42. Epub 2006 Jan 6. 2006
|
| 52 | IP2, IKBKG, OLEDAID
|
| The NEMO mutation creating the most-upstream premature stop codon is hypomorphic because of a reinitiation of translation.
|
| Puel A, Reichenbach J, Bustamante J, Ku CL, Feinberg J, Doffinger R, Bonnet M, Filipe-Santos O, Beaucoudrey L, Durandy A, Horneff G, Novelli F, Wahn V, Smahi A, Israel A, Niehues T, Casanova JL.
|
| Am J Hum Genet 78(4):691-701. Epub 2006 Feb 15. 2006
|
| 53 | IKBKG
|
| Multiple regulatory regions and tissue-specific transcription initiation mediate the expression of NEMO/IKKgamma gene.
|
| Fusco F, Mercadante V, Miano MG, Ursini MV.
|
| Gene 383:99-107. Epub 2006 Aug 2. 2006
|
| 54 | TLR8, IKBKG, MAP3K3
|
| TLR8-mediated NF-kappaB and JNK activation are TAK1-independent and MEKK3-dependent.
|
| Qin J, Yao J, Cui G, Xiao H, Kim TW, Fraczek J, Wightman P, Sato S, Akira S, Puel A, Casanova JL, Su B, Li X.
|
| J Biol Chem 281(30):21013-21. Epub 2006 May 31. 2006
|
| 55 | IKBKG
|
| Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
|
| Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD.
|
| Nat Cell Biol 8(4):398-406. Epub 2006 Mar 19. Erratum in: Nat Cell Biol. 2006 Apr;8(4):424. 2006
|
| 56 | RIPK1, IKBKG
|
| Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO.
|
| Ea CK, Deng L, Xia ZP, Pineda G, Chen ZJ.
|
| Mol Cell 22(2):245-57. Epub 2006 Apr 6. 2006
|
| 57 | IKBKG
|
| X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production.
|
| Filipe-Santos O, Bustamante J, Haverkamp MH, Vinolo E, Ku CL, Puel A, Frucht DM, Christel K, von Bernuth H, Jouanguy E, Feinberg J, Durandy A, Senechal B, Chapgier A, Vogt G, de Beaucoudrey L, Fieschi C, Picard C, Garfa M, Chemli J, Bejaoui M, Tsolia MN, Kutukculer N, Plebani A, Notarangelo L, Bodemer C, Geissmann F, Isra‘l A, VŽron M, Knackstedt M, Barbouche R, Abel L, Magdorf K, Gendrel D, Agou F, Holland SM, Casanova JL.
|
| J Exp Med 203(7):1745-59. Epub 2006 Jul 3. 2006
|
| 58 | IKBKG
|
| Multiple regulatory regions and tissue-specific transcription initiation mediate the expression of NEMO/IKKgamma gene.
|
| Fusco F, Mercadante V, Miano MG, Ursini MV.
|
| Gene 383:99-107. Epub 2006 Aug 2.
2006
|
| 59 | IKBKG, IMD33
|
| X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production.
|
| Filipe-Santos O, Bustamante J, Haverkamp MH, Vinolo E, Ku CL, Puel A, Frucht DM, Christel K, von Bernuth H, Jouanguy E, Feinberg J, Durandy A, Senechal B, Chapgier A, Vogt G, de Beaucoudrey L, Fieschi C, Picard C, Garfa M, Chemli J, Bejaoui M, Tsolia MN, Kutukculer N, Plebani A, Notarangelo L, Bodemer C, Geissmann F, Israël A, Véron M, Knackstedt M, Barbouche R, Abel L, Magdorf K, Gendrel D, Agou F, Holland SM, Casanova JL.
|
| J Exp Med 203(7):1745-59. Epub 2006 Jul 3.
2006
|
| 60 | IKBKG, EDAID
|
| NEMO mutations in 2 unrelated boys with severe infections and conical teeth.
|
| Ku CL, Dupuis-Girod S, Dittrich AM, Bustamante J, Santos OF, Schulze I, Bertrand Y, Couly G, Bodemer C, Bossuyt X, Picard C, Casanova JL.
|
| Pediatrics 115(5):e615-9. Epub 2005 Apr 15. 2005
|
| 61 | IKBKG, IP2
|
| A new mutation in exon 7 of NEMO gene: late skewed X-chromosome inactivation in an incontinentia pigmenti female patient with immunodeficiency.
|
| Martinez-Pomar N, Munoz-Saa I, Heine-Suner D, Martin A, Smahi A, Matamoros N.
|
| Hum Genet 118(3-4):458-65. Epub 2005 Oct 14. 2005
|
| 62 | NFKB1, IKBKG
|
| Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.
|
| Zhou H, Wertz I, O'Rourke K, Ultsch M, Seshagiri S, Eby M, Xiao W, Dixit VM.
|
| Nature 427(6970):167-71. Epub 2003 Dec 24. 2004
|
| 63 | IKBKG, IP2
|
| Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation.
|
| Fusco F, Bardaro T, Fimiani G, Mercadante V, Miano MG, Falco G, Israel A, Courtois G, D'Urso M, Ursini MV.
|
| Hum Mol Genet 13(16):1763-73. Epub 2004 Jun 30. 2004
|
| 64 | IKBKG, OLEDAID
|
| X-linked ectodermal dysplasia and immunodeficiency caused by reversion mosaicism of NEMO reveals a critical role for NEMO in human T-cell development and/or survival.
|
| Nishikomori R, Akutagawa H, Maruyama K, Nakata-Hizume M, Ohmori K, Mizuno K, Yachie A, Yasumi T, Kusunoki T, Heike T, Nakahata T.
|
| Blood 103(12):4565-72. Epub 2004 Jan 15. 2004
|
| 65 | CARD10, CARD11, IKBKG
|
| Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator.
|
| Stilo R, Liguoro D, Di Jeso B, Formisano S, Consiglio E, Leonardi A, Vito P.
|
| J Biol Chem 279(33):34323-31. Epub 2004 Jun 7. 2004
|
| 66 | IKBKG, EDAID
|
| Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation.
|
| Jain A, Ma CA, Lopez-Granados E, Means G, Brady W, Orange JS, Liu S, Holland S, Derry JM.
|
| J Clin Invest 114(11):1593-602. 2004
|
| 67 | CYLD, IKBKB, IKBKG, MAPK8, MAP2K7
|
| Negative regulation of JNK signaling by the tumor suppressor CYLD.
|
| Reiley W, Zhang M, Sun SC.
|
| J Biol Chem 279(53):55161-7. Epub 2004 Oct 20. 2004
|
| 68 | IKBKG
|
| The role of nuclear factor-kappaB essential modulator (NEMO) in B cell development and survival
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