| 1 | IGF2R, NFIL3
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| NFIL3 suppresses hypoxia-induced apoptotic cell death by targeting the insulin-like growth factor 2 receptor.
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| Lin KH, Kuo CH, Kuo WW, Ho TJ, Pai P, Chen WK, Pan LF, Wang CC, Padma VV, Huang CY.
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| J Cell Biochem 116(6):1113-20. doi: 10.1002/jcb.25067.
2015
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| 2 | IGF2R, NFIL3
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| NFIL3 suppresses hypoxia-induced apoptotic cell death by targeting the insulin-like growth factor 2 receptor.
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| Lin KH, Kuo CH, Kuo WW, Ho TJ, Pai P, Chen WK, Pan LF, Wang CC, Padma VV, Huang CY.
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| J Cell Biochem 116(6):1113-20. doi: 10.1002/jcb.25067.
2015
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| 3 | IGF2R, LCK
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| The late endosomal transporter CD222 directs the spatial distribution and activity of Lck.
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| Pfisterer K, Forster F, Paster W, Supper V, Ohradanova-Repic A, Eckerstorfer P, Zwirzitz A, Donner C, Boulegue C, Schiller HB, Ondrovičová G, Acuto O, Stockinger H, Leksa V.
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| J Immunol 193(6):2718-32. doi: 10.4049/jimmunol.1303349. Epub 2014 Aug 15.
2014
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| 4 | IGF2R
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| Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides.
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| Gao N, Shang J, Huynh D, Manthati VL, Arias C, Harding HP, Kaufman RJ, Mohr I, Ron D, Falck JR, Lehrman MA.
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| Mol Biol Cell 22(17):2994-3009. Epub 2011 Jul 7.
2011
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| 5 | APP, IGF2R, PACS1, SORCS1, SORCS2, SORCS3, SORL1, SORT1
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| VPS10P-domain receptors - regulators of neuronal viability and function.
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| Willnow TE, Petersen CM, Nykjaer A.
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| Nat Rev Neurosci. 9(12):899-909. 2009
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| 6 | IGF2R
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| Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11.
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| Williams C, Rezgui D, Prince SN, Zaccheo OJ, Foulstone EJ, Forbes BE, Norton RS, Crosby J, Hassan AB, Crump MP.
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| Structure 15(9):1065-78. 2007
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| 7 | IGF2R
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| A novel binding site for the human insulin-like growth factor-II (IGF-II)/mannose 6-phosphate receptor on IGF-II.
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| Delaine C, Alvino CL, McNeil KA, Mulhern TD, Gauguin L, De Meyts P, Jones EY, Brown J, Wallace JC, Forbes BE.
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| J Biol Chem 282(26):18886-94. Epub 2007 May 2. 2007
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| 8 | IGF2R, IGF2
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| Insulin-like growth factor 2 (IGF2) and IGF2 receptor gene variants are associated with fetal growth.
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| Kaku K, Osada H, Seki K, Sekiya S.
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| Acta Paediatr 96(3):363-7. 2007
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| 9 | IGF2R
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| Mannose-6-phosphate/insulin-like growth factor II receptor expression and tumor development.
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| Hébert E.
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| Biosci Rep. 26(1):7-17. 2006
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| 10 | IGF2R
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| Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse.
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| Vu TH, Li T, Hoffman AR.
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| Hum Mol Genet 13(19):2233-45. Epub 2004 Aug 04. 2004
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| 11 | IGF2R
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| Insulin-like growth factor II receptor gene-167 genotype increases the risk of oral squamous cell carcinoma in humans.
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| Zavras AI, Pitiphat W, Wu T, Cartsos V, Lam A, Douglass CW, Diehl SR.
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| Cancer Res. 63(2):296-7. 2003
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| 12 | IGF2R
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| The secreted glycoprotein CREG inhibits cell growth dependent on the mannose-6-phosphate/insulin-like growth factor II receptor.
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| Di Bacco A, Gill G.
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| Oncogene. 22(35):5436-45. 2003
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| 13 | IGF2R
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| The IGF2 receptor is a USF2-specific target in nontumorigenic mammary epithelial cells but not in breast cancer cells.
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| Szentirmay MN, Yang HX, Pawar SA, Vinson C, Sawadogo M.
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| J Biol Chem. 278(39):37231-40. 2003
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| 14 | IGF2R
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| Allelic IGF2R repression does not correlate with expression of antisense RNA in human extraembryonic tissues.
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| Oudejans CB, Westerman B, Wouters D, Gooyer S, Leegwater PA, van Wijk IJ, Sleutels F.
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| Genomics 73(3):331-7. 2001
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| 15 | IGF2R
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| Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations.
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| Killian JK, Oka Y, Jang HS, Fu X, Waterland RA, Sohda T, Sakaguchi S, Jirtle RL.
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| Hum Mutat 18(1):25-31. 2001
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| 16 | IGF2R
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| Loss of heterozygosity at the mannose 6-phosphate/insulin-like growth factor 2 receptor locus: a frequent but late event in adrenocortical tumorigenesis.
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| Leboulleux S, Gaston V, Boulle N, Le Bouc Y, Gicquel C.
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| Eur J Endocrinol 144(2):163-8. 2001
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| 17 | IGF2R
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| Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor.
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| Zhu Y, Doray B, Poussu A, Lehto VP, Kornfeld S.
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| Science. 292(5522):1716-8. 2001
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| 18 | GZMB, IGF2R
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| Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.
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| Motyka B, Korbutt G, Pinkoski MJ, Heibein JA, Caputo A, Hobman M, Barry M, Shostak I, Sawchuk T, Holmes CF, Gauldie J, Bleackley RC.
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| Cell 103(3):491-500. 2000
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| 19 | IGF2R
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| Recognition of the 300-kDa mannose 6-phosphate receptor cytoplasmic domain by 47-kDa tail-interacting protein.
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| Orsel JG, Sincock PM, Krise JP, Pfeffer SR.
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| Proc Natl Acad Sci U S A. 97(16):9047-51. 2000
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| 20 | IGF2R
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| Genomic structure of the human M6P/IGF2 receptor.
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| Killian JK, et al.
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| Mamm Genome 10(1):74-7. No abstract available 1999
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| 21 | IGF2R
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| Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations.
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| Byrd JC, Devi GR, de Souza AT, Jirtle RL, MacDonald RG.
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| J Biol Chem 274(34):24408-16 1999
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| 22 | BAX, IGF2R, TGFBR2
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| The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different target genes : a study of the TGFbeta RII, IGFII R, and BAX genes.
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| Oliveira C, et al.
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| Am J Pathol 153 : 1211-1219. 1998
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| 23 | BAX, IGF2R, PTEN
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| The PTEN, BAX, and IGFIIR genes are mutated in endometrial atypical hyperplasia.
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| Yoshinaga K, et al.
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| Jpn J Cancer Res 89 : 985-990. 1998
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| 24 | IGF2R
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| Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction
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| Nykjaer A, Christensen EI, Vorum H, Hager H, Petersen CM, Rĝigaard H, Min HY, Vilhardt F, Mĝller LB, Kornfeld S, Gliemann J.
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| J Cell Biol. 141(3):815-28. 1998
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| 25 | IGF2R
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| Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor.
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| Xu YQ, et al.
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| Oncogene 14 : 1041-1046. 1997
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| 26 | IGF2R, ST8
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| Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid.
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| Kang JX, Li Y, Leaf A.
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| Proc Natl Acad Sci U S A 94(25):13671-6. Erratum in: Proc Natl Acad Sci U S A 2001 Dec 18;98(26):15393. 1997
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| 27 | IGF2R
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| Translocation between chromosomes 6 and 15 (45,XX,t(6;15)(q25;q11.2) with further evidence for lack of imprinting of the insulin-like growth factor II/mannose-6-phosphate receptor in humans.
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| Treacy E, et al.
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| J Med Genet 33 : 42-46. 1996
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| 28 | IGF2R
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| Maternal-specific methylation of the human IGF2R gene is not accompanied by allele-specific transcription.
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| Riesewijk AM, et al.
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| Genomics 31 : 158-166. 1996
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| 29 | IGF2R, TGFBR2
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| Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours.
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| Souza RF, et al.
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| Nat Genet 14 : 255-257. 1996
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| 30 | TSG6E, IGF2R
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| M6P/GF2R gene is mutated in human hepatocellular carcinomas with loss ofheterozygosity.
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| De souza AT, et al.
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| Nat Genet 11 : 447-449. 1995
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| 31 | D6S61, MARCKS, EZR, IGF2R, TRDP
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| Subregional mapping of 8 single copy loci to chromosome 6 by fluorescence in situ hybridization.
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| Rao PH, et al.
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| Cytogenet Cell Genet 66 : 272-273. 1994
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| 32 | IGF2R, TRDP
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| A 2-Mb YAC contig linking the plasminogen-apoprotein(a) gene family to the insulin-like growth factor 2 receptor (IGF2R) gene on the telomeric region of chromosome 6 (6q26-q27).
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| Acquati F, et al.
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| Genomics 22 : 664-666. 1994
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| 33 | IGF2R
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| Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.
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| Lau MM, Stewart CE, Liu Z, Bhatt H, Rotwein P, Stewart CL.
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| Genes Dev. 8(24):2953-63. 1994
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| 34 | IGF2R
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| Functional polymorphism in the parental imprinting of the human IGF2R gene.
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| Xu Y, et al.
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| Biochem Biophys Res Commun 197 : 747-754. 1993
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| 35 | IGF2R
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| Dinucleotide repeat polymorphism at the IGF2R locus.
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| Goto J, et al.
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| Nucleic Acids Res 20 : 923. 1992
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| 36 | IGF2R
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| Improving the polymorphism content of the 3' UTR of the human IGF2R gene.
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| Hol FA, et al.
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| Hum Mol Genet 1 : 347. 1992
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| 37 | IGF2R
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| SacI RFLP in the insulin-like growth factor 2 receptor gene (IGF2R) on human chromosome 6q.
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| Hauptschein R, et al.
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| Nucleic Acids Res 19 : 6974. 1991
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| 38 | IGF2R
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| Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse.
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| Laureys G, et al.
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| Genomics 3 : 224-229. 1988
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| 39 | IGF2R
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| Cloning of the bovine 215-kDa cation-independent mannose 6-phosphate receptor.
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| Lobel P, et al.
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| Proc Natl Acad Sci U S A 84 : 2233-2237. 1987
|