Citations for
1ADAM17, IFNG
A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.
Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.
Sci Rep 6:32259. doi: 10.1038/srep32259. 2016
2CD274, IFNG, JAK1, JAK2
Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression.
Bellucci R, Martin A, Bommarito D, Wang K, Hansen SH, Freeman GJ, Ritz J.
Oncoimmunology Mar 2;4(6):e1008824. doi: 10.1080/2162402X.2015.1008824. eCollection 2015 Jun. 2015
3IFNG, PRDM1, TLE4
Tle4 regulates epigenetic silencing of gamma interferon expression during effector T helper cell tolerance.
Bandyopadhyay S, Valdor R, Macian F.
Mol Cell Biol 34(2):233-45. doi: 10.1128/MCB.00902-13. Epub 2013 Nov 4. 2014
4IFNG, IL33, PSMB9, STAT1
IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism.
Kopach P, Lockatell V, Pickering EM, Haskell RE, Anderson RD, Hasday JD, Todd NW, Luzina IG, Atamas SP.
J Biol Chem 289(17):11829-43. doi: 10.1074/jbc.M113.534396. Epub 2014 Mar 11. 2014
5GBP1, IFNG
Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.
Forster F, Paster W, Supper V, Schatzlmaier P, Sunzenauer S, Ostler N, Saliba A, Eckerstorfer P, Britzen-Laurent N, Schütz G, Schmid JA, Zlabinger GJ, Naschberger E, Stürzl M, Stockinger H.
J Immunol 192(2):771-81. doi: 10.4049/jimmunol.1300377. Epub 2013 Dec 13. 2014
6IFNG, TBX21
NK cells gain higher IFN-γ competence during terminal differentiation.
Luetke-Eversloh M, Cicek BB, Siracusa F, Thom JT, Hamann A, Frischbutter S, Baumgrass R, Chang HD, Thiel A, Dong J, Romagnani C.
Eur J Immunol 44(7):2074-84. doi: 10.1002/eji.201344072. Epub 2014 May 19. 2014
7IFNG
Genetic polymorphisms of IFNG and IFNGR1 in association with the risk of pulmonary tuberculosis.
Lü J, Pan H, Chen Y, Tang S, Feng Y, Qiu S, Zhang S, Wu L, Xu R, Peng X, Wang J, Lu C.
Gene 543(1):140-4. doi: 10.1016/j.gene.2014.03.042. Epub 2014 Mar 25. 2014
8IFNG, NR1H3
Identification of interferon-γ as a new molecular target of liver X receptor.
Wang Q, Ma X, Chen Y, Zhang L, Jiang M, Li X, Xiang R, Miao R, Hajjar DP, Duan Y, Han J.
Biochem J 459(2):345-54. doi: 10.1042/BJ20131442. 2014
9IFNG
IFN-γ-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair.
Kunis G, Baruch K, Rosenzweig N, Kertser A, Miller O, Berkutzki T, Schwartz M.
Brain 136(Pt 11):3427-40. doi: 10.1093/brain/awt259. Epub 2013 Oct 1. 2013
10IFNG
Interferon-γ and systemic autoimmunity.
Pollard KM, Cauvi DM, Toomey CB, Morris KV, Kono DH.
Discov Med 16(87):123-31. Review. 2013
11IFNG, IRF1, OPTN
IRF-1-binding site in the first intron mediates interferon-γ-induced optineurin promoter activation.
Sudhakar C, Vaibhava V, Swarup G.
Biochem Biophys Res Commun 437(1):179-84. doi: 10.1016/j.bbrc.2013.06.065. Epub 2013 Jun 27. 2013
12IFNG, MYD88
MyD88 signaling in CD4 T cells promotes IFN-γ production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection.
Zhang Y, Jones M, McCabe A, Winslow GM, Avram D, MacNamara KC.
J Immunol 190(9):4725-35. doi: 10.4049/jimmunol.1203024. Epub 2013 Mar 22. 2013
13IFNG, IL33
Evidence for a regulatory loop between IFN-γ and IL-33 in skin inflammation.
Seltmann J, Werfel T, Wittmann M.
Exp Dermatol 22(2):102-7. doi: 10.1111/exd.12076. 2013
14IFNG, TNFSF13B
Induction of BAFF expression by IFN-γ via JAK/STAT signaling pathways in human intestinal epithelial cells.
Woo SJ, Im J, Jeon JH, Kang SS, Lee MH, Yun CH, Moon EY, Song MK, Kim HH, Han SH.
J Leukoc Biol 93(3):363-8. doi: 10.1189/jlb.0412210. Epub 2012 Dec 27. 2013
15IFNG, IL26
Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element.
Collins PL, Henderson MA, Aune TM.
Genes Immun 13(6):481-8. doi: 10.1038/gene.2012.22. Epub 2012 May 24. 2012
16IFNG, RUNX3, TWIST1
Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.
Pham D, Vincentz JW, Firulli AB, Kaplan MH.
J Immunol 189(2):832-40. doi: 10.4049/jimmunol.1200854. Epub 2012 Jun 8. 2012
17FXN, IFNG
Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model.
Tomassini B, Arcuri G, Fortuni S, Sandi C, Ezzatizadeh V, Casali C, Condò I, Malisan F, Al-Mahdawi S, Pook M, Testi R.
Hum Mol Genet 21(13):2855-61. doi: 10.1093/hmg/dds110. Epub 2012 Mar 23. 2012
18IFNA1, IFNG
Autocrine IFN-γ promotes naive CD8 T cell differentiation and synergizes with IFN-α to stimulate strong function.
Curtsinger JM, Agarwal P, Lins DC, Mescher MF.
J Immunol 189(2):659-68. doi: 10.4049/jimmunol.1102727. Epub 2012 Jun 15. 2012
19IFNG, TBX21
Ikaros silences T-bet expression and interferon-gamma production during T helper 2 differentiation.
Thomas RM, Chen C, Chunder N, Ma L, Taylor J, Pearce EJ, Wells AD.
J Biol Chem 285(4):2545-53. Epub 2009 Nov 18.PMID: 19923223 2010
20DUOX2, IFNG
IFNgamma mediates DUOX2 expression via a STAT-independent signaling pathway.
Hill T 3rd, Xu C, Harper RW.
Biochem Biophys Res Commun 395(2):270-4. Epub 2010 Apr 8. 2010
21IFNG, IL27, SPP1
Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation.
Murugaiyan G, Mittal A, Weiner HL.
Proc Natl Acad Sci U S A 107(25):11495-500. Epub 2010 Jun 7.PMID: 20534530 2010
22COL1A2, IFNG, RFXANK
RFXB and its splice variant RFXBSV mediate the antagonism between IFNgamma and TGFbeta on COL1A2 transcription in vascular smooth muscle cells.
Fang M, Kong X, Li P, Fang F, Wu X, Bai H, Qi X, Chen Q, Xu Y.
Nucleic Acids Res 37(13):4393-406. Epub 2009 May 22. 2009
23IFNG
Interferon-gamma axis in graft arteriosclerosis.
Tellides G, Pober JS.
Circ Res 100(5):622-32. Review. 2007
24IFNG, IGF1
In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth.
Conti L, Regis G, Longo A, Bernabei P, Chiarle R, Giovarelli M, Novelli F.
Blood 109(6):2496-504. Epub 2006 Dec 5. 2007
25IFNG
Proteasome response to interferon-gamma is altered in senescent human fibroblasts.
Stratford FL, Chondrogianni N, Trougakos IP, Gonos ES, Rivett AJ.
FEBS Lett 580(16):3989-94. Epub 2006 Jun 21. 2006
26TBX21, IFNG
Identification of a novel type 1 diabetes susceptibility gene, T-bet.
Sasaki Y, Ihara K, Matsuura N, Kohno H, Nagafuchi S, Kuromaru R, Kusuhara K, Takeya R, Hoey T, Sumimoto H, Hara T.
Hum Genet 115(3):177-84. Epub 2004 Jul 06. 2004
27IFNG, EIF2AK2
Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR.
Ben-Asouli Y, Banai Y, Pel-Or Y, Shir A, Kaempfer R.
Cell 108(2):221-32. 2002
28SOCS1, IFNG
The tumor suppressor activity of SOCS-1.
Rottapel R, Ilangumaran S, Neale C, La Rose J, Ho JM, Nguyen MH, Barber D, Dubreuil P, de Sepulveda P.
Oncogene 21(28):4351-62. 2002
29IFNG, STAT1
Biologic consequences of Stat1-independent IFN signaling.
Gil MP, Bohn E, O'Guin AK, Ramana CV, Levine B, Stark GR, Virgin HW, Schreiber RD.
Proc Natl Acad Sci U S A 98(12):6680-5. 2001
30IFNG, STAT1
Stat1-independent regulation of gene expression in response to IFN-gamma.
Ramana CV, Gil MP, Han Y, Ransohoff RM, Schreiber RD, Stark GR.
Proc Natl Acad Sci U S A 98(12):6674-9. 2001
31IFNG
Interferon gamma gene polymorphism and susceptibility to, and severity of, rheumatoid arthritis.
Constantin A, Navaux F, Lauwers-Cances V, Abbal M, van Meerwijk JP, Mazieres B, Cambon-Thomsen A, Cantagrel A.
Lancet 358(9298):2051-2. 2001
32BRCA1, IFNG, STAT1
Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes.
Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM.
Proc Natl Acad Sci U S A 97(10):5208-13. 2000
33IFNG, TNFRSF11A, TNFRSF11B, TRAF6
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma.
Takayanagi H, Ogasawara K, Hida S, Chiba T, Murata S, Sato K, Takaoka A, Yokochi T, Oda H, Tanaka K, Nakamura K, Taniguchi T.
Nature 408(6812):600-5. 2000
34IFNG, IL2, NMI, STAT1, STAT5A
Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.
Zhu M, et al.
Cell 96(1):121-30. 1999
35IFN1@, IFNG, STAT1
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma.
Bromberg JF, Horvath CM, Wen Z, Schreiber RD, Darnell JE Jr.
Proc Natl Acad Sci U S A 93(15):7673-8. 1996
36IFNG
Mapping of the immune interferon gamma gene (IFNG) to chromosome band 12q14 by fluorescence in situ hybridization.
Zimonjic DB, et al.
Cytogenet Cell Genet 71 : 247-248. 1995
37IFNG, MDM2
The gene coding for interferon-gamma is linked to the D12S335 and D12S313 microsatellites and to the MDM2 gene.
Bureau JF, et al.
Genomics 28 : 109-112. 1995
38IFN1@, IFNB1, IFNG, IFNP11, IFNP12, IFNW1, IFNWP2, IFNWP5, IFNWP9, IFNWP15, IFNWP18, IFNWP19, IFNP20, IFNP23, IFNP24
Structure of the human type-I interferon gene cluster determined from a YAC clone contig.
Diaz MO, et al.
Genomics 22 : 540-552. 1994
39IFNG
Dinucleotide repeat polymorphism in the inter-feron-gamma (IFNG) gene.
Ruiz-Linares A.
Hum Mol Genet 2 : 1508. 1993
40IL10, IFNG, CSF2
Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.
Pisa P, et al.
Proc Natl Acad Sci U S A 89 : 7708-7712. 1992
41IFNG
Interferon-gamma gene expression in unstimulated bone marrow monocuclear cells predicts a good response to cyclosporine therapy in aplastic anemia.
Nakao S, et al.
Blood 79 : 2532-2535. 1992
42IFNG
Human B cell lines express the interferon gamma gene.
Dayton MA, et al.
Cytokine 4 : 454-460. 1992
43IFNG
Gamma-interferon increases metaiodobenzylguanidine incorporation and retention in human neuroblastoma cells.
Montaldo PG, et al.
Cancer Res 52 : 4960-4964. 1992
44IFNG
The use of polymerase chain reaction (PCR) for assessing interferon-gamma (INF-gamma) mRNA levels in human lymphocytes.
Pazderka F, et al.
Transplant Proc 23 : 241-242. 1990
45IFNG
Human immune interferon gene is located on chromosome 12.
Naylor SL, et al.
J Exp Med 157 : 1020-1027. 1983
46IFN1@, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA16, IFNA17, IFNA21, IFNAP22, IFNB1, IFNG
Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization.
Trent JM, et al.
Proc Natl Acad Sci U S A 79 : 7809-7813. 1982