| 1 | IFNB1, S100P
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| Highly specific interaction of monomeric S100P protein with interferon beta.
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| Kazakov AS, Mayorov SA, Deryusheva EI, Avkhacheva NV, Denessiouk KA, Denesyuk AI, Rastrygina VA, Permyakov EA, Permyakov SE.
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| Int J Biol Macromol 143:633-639. doi: 10.1016/j.ijbiomac.2019.12.039. Epub 2019 Dec 7.
2020
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| 2 | IFNB1, ILF3
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| ILF3 contributes to the establishment of the antiviral type I interferon program.
|
| Watson SF, Bellora N, Macias S.
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| Nucleic Acids Res 48(1):116-129. doi: 10.1093/nar/gkz1060.
2020
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| 3 | iFNB1
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| IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation.
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| Kumaran Satyanarayanan S, El Kebir D, Soboh S, Butenko S, Sekheri M, Saadi J, Peled N, Assi S, Othman A, Schif-Zuck S, Feuermann Y, Barkan D, Sher N, Filep JG, Ariel A.
|
| Nat Commun 10(1):3471. doi: 10.1038/s41467-019-10903-9.
2019
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| 4 | DDX58, IFIH1, IFNB1, IRF7
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| Deficient pulmonary IFN-β expression in COPD patients.
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| García-Valero J, Olloquequi J, Montes JF, Rodríguez E, Martín-Satué M, Texidó L, Ferrer Sancho J.
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| PLoS One 14(6):e0217803. doi: 10.1371/journal.pone.0217803. eCollection 2019. Erratum in: PLoS One. 2019 Jul 1;14(7):e0219349.
2019
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| 5 | CD274, IFNB1, IRF9, PDCD1
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| Interferon-β signal may up-regulate PD-L1 expression through IRF9-dependent and independent pathways in lung cancer cells.
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| Morimoto Y, Kishida T, Kotani SI, Takayama K, Mazda O.
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| Biochem Biophys Res Commun 507(1-4):330-336. doi: 10.1016/j.bbrc.2018.11.035. Epub 2018 Nov 14.
2018
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| 6 | IFNB1, ZBTB7B
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| The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.
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| Nikopoulou C, Panagopoulos G, Sianidis G, Psarra E, Ford E, Thanos D.
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| Mol Cell 71(2):352-361.e5. doi: 10.1016/j.molcel.2018.06.019. Epub 2018 Jul 12. Erratum in: Mol Cell. 2019 Apr 18;74(2):409-410.
2018
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| 7 | DDX58, IFIH1, IFNB1
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| Identification of new type I interferon-stimulated genes and investigation of their involvement in IFN-β activation.
|
| Zhang X, Yang W, Wang X, Zhang X, Tian H, Deng H, Zhang L, Gao G.
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| Protein Cell 9(9):799-807. doi: 10.1007/s13238-018-0511-1. Epub 2018 Feb 9.
2018
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| 8 | IFNB1, XAF1
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| Metabolic Endotoxemia-Activated Macrophages Promote Pancreatic β Cell Death via IFNβ-Xaf1 Pathway.
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| Tsuruta M, Iwashita M, Shinjo T, Matsunaga H, Yamashita A, Nishimura F.
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| Horm Metab Res 50(2):160-167. doi: 10.1055/s-0043-121467. Epub 2017 Nov 13.
2018
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| 9 | IFNB1, MEF2C
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| Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.
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| Deczkowska A, Matcovitch-Natan O, Tsitsou-Kampeli A, Ben-Hamo S, Dvir-Szternfeld R, Spinrad A, Singer O, David E, Winter DR, Smith LK, Kertser A, Baruch K, Rosenzweig N, Terem A, Prinz M, Villeda S, Citri A, Amit I, Schwartz M.
|
| Nat Commun 8(1):717. doi: 10.1038/s41467-017-00769-0.
2017
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| 10 | IFNB1, RIPK1, RIPK3
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| Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.
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| Saleh D, Najjar M, Zelic M, Shah S, Nogusa S, Polykratis A, Paczosa MK, Gough PJ, Bertin J, Whalen M, Fitzgerald KA, Slavov N, Pasparakis M, Balachandran S, Kelliher M, Mecsas J, Degterev A.
|
| J Immunol 198(11):4435-4447. doi: 10.4049/jimmunol.1601717. Epub 2017 May 1.
2017
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| 11 | IFNB1
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| Direct Antimicrobial Activity of IFN-β.
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| Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM.
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| J Immunol 198(10):4036-4045. doi: 10.4049/jimmunol.1601226. Epub 2017 Apr 14.
2017
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| 12 | IFNB1
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| Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production.
|
| Zhang X, Ye Z, Pei Y, Qiu G, Wang Q, Xu Y, Shen B, Zhang J.
|
| Cell Mol Immunol 13(5):578-83. doi: 10.1038/cmi.2015.35. Epub 2015 May 11.
2016
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| 13 | IFNB1
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| Interferon Beta: From Molecular Level to Therapeutic Effects.
|
| Haji Abdolvahab M, Mofrad MR, Schellekens H.
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| Int Rev Cell Mol Biol 326:343-72. doi: 10.1016/bs.ircmb.2016.06.001. Epub 2016 Jul 20. Review.
2016
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| 14 | IFNB1, RB1
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| Rb selectively inhibits innate IFN-β production by enhancing deacetylation of IFN-β promoter through HDAC1 and HDAC8.
|
| Meng J, Liu X, Zhang P, Li D, Xu S, Zhou Q, Guo M, Huai W, Chen X, Wang Q, Li N, Cao X.
|
| J Autoimmun 73:42-53. doi: 10.1016/j.jaut.2016.05.012. Epub 2016 Jun 4. Erratum in: J Autoimmun. 2020 Jan;106:102380.
2016
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| 15 | IFNB1, IRF1, IRF5
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| Effects of IRF1 and IFN-β interaction on the M1 polarization of macrophages and its antitumor function.
|
| Xie C, Liu C, Wu B, Lin Y, Ma T, Xiong H, Wang Q, Li Z, Ma C, Tu Z.
|
| Int J Mol Med 38(1):148-60. doi: 10.3892/ijmm.2016.2583. Epub 2016 May 10.
2016
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| 16 | IFNB1, IL10, SYK, TLR4
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| Syk negatively regulates TLR4-mediated IFNβ and IL-10 production and promotes inflammatory responses in dendritic cells.
|
| Yin H, Zhou H, Kang Y, Zhang X, Duan X, Alnabhan R, Liang S, Scott DA, Lamont RJ, Shang J, Wang H.
|
| Biochim Biophys Acta 1860(3):588-98. doi: 10.1016/j.bbagen.2015.12.012. Epub 2015 Dec 17.
2016
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| 17 | IFNB1, TRIM33
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| TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation.
|
| Ferri F, Parcelier A, Petit V, Gallouet AS, Lewandowski D, Dalloz M, van den Heuvel A, Kolovos P, Soler E, Squadrito ML, De Palma M, Davidson I, Rousselet G, Romeo PH.
|
| Nat Commun 6:8900. doi: 10.1038/ncomms9900.
2015
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| 18 | IFNB1
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| Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia.
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| Ejlerskov P, Hultberg JG, Wang J, Carlsson R, Ambjørn M, Kuss M, Liu Y, Porcu G, Kolkova K, Friis Rundsten C, Ruscher K, Pakkenberg B, Goldmann T, Loreth D, Prinz M, Rubinsztein DC, Issazadeh-Navikas S.
|
| Cell 163(2):324-39. doi: 10.1016/j.cell.2015.08.069.
2015
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| 19 | IFNA1, IFNB1
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| Blockade of interferon Beta, but not interferon alpha, signaling controls persistent viral infection.
|
| Ng CT, Sullivan BM, Teijaro JR, Lee AM, Welch M, Rice S, Sheehan KC, Schreiber RD, Oldstone MB.
|
| Cell Host Microbe 17(5):653-61. doi: 10.1016/j.chom.2015.04.005.
2015
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| 20 | HSPD1, IFNB1, IRF3
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| HSPD1 interacts with IRF3 to facilitate interferon-beta induction.
|
| Lin L, Pan S, Zhao J, Liu C, Wang P, Fu L, Xu X, Jin M, Zhang A.
|
| PLoS One 9(12):e114874. doi: 10.1371/journal.pone.0114874. eCollection 2014.
2014
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| 21 | IFNB1, IRF9
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| Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.
|
| McComb S, Cessford E, Alturki NA, Joseph J, Shutinoski B, Startek JB, Gamero AM, Mossman KL, Sad S.
|
| Proc Natl Acad Sci U S A 111(31):E3206-13. doi: 10.1073/pnas.1407068111. Epub 2014 Jul 21.
2014
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| 22 | IFNB1
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| Beta interferon regulation of glucose metabolism is PI3K/Akt dependent and important for antiviral activity against coxsackievirus B3.
|
| Burke JD, Platanias LC, Fish EN.
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| J Virol 88(6):3485-95. doi: 10.1128/JVI.02649-13. Epub 2014 Jan 8.
2014
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| 23 | DDX58, IFNB1, TBK1, TRIM11
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| TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1.
|
| Lee Y, Song B, Park C, Kwon KS.
|
| PLoS One 8(5):e63255. doi: 10.1371/journal.pone.0063255. Print 2013. 2013
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| 24 | FOXO3, IFNB1, IKBKE
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| FOXO3 as a new IKK-ε-controlled check-point of regulation of IFN-β expression.
|
| Luron L, Saliba D, Blazek K, Lanfrancotti A, Udalova IA.
|
| Eur J Immunol 42(4):1030-7. doi: 10.1002/eji.201141969.
2012
|
| 25 | IFNB1
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| IFN-β induces the proliferation of CD4+CD25+Foxp3+ regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis.
|
| Chen M, Chen G, Deng S, Liu X, Hutton GJ, Hong J.
|
| J Neuroimmunol 242(1-2):39-46. Epub 2011 Nov 21.
2012
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| 26 | IFNB1, IL10
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| The role of glycogen synthase kinase 3 in regulating IFN-β-mediated IL-10 production.
|
| Wang H, Brown J, Garcia CA, Tang Y, Benakanakere MR, Greenway T, Alard P, Kinane DF, Martin M.
|
| J Immunol 186(2):675-84. Epub 2010 Dec 15.
2011
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| 27 | IFNB1
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| Type I IFN promotes IL-10 production from T cells to suppress Th17 cells and Th17-associated autoimmune inflammation.
|
| Zhang L, Yuan S, Cheng G, Guo B.
|
| PLoS One 6(12):e28432. Epub 2011 Dec 6.
2011
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| 28 | IFNB1
|
| Interferon-β signaling contributes to Ras transformation.
|
| Tsai YC, Pestka S, Wang LH, Runnels LW, Wan S, Lyu YL, Liu LF.
|
| PLoS One 6(8):e24291. Epub 2011 Aug 29.
2011
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| 29 | IFNB1
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| Interferon β-1b directly modulates human neural stem/progenitor cell fate.
|
| Arscott WT, Soltys J, Knight J, Mao-Draayer Y.
|
| Brain Res 1413:1-8. Epub 2011 Jul 23.
2011
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| 30 | IFNB1
|
| B cells as a therapeutic target for IFN-β in relapsing-remitting multiple sclerosis.
|
| Ramgolam VS, Sha Y, Marcus KL, Choudhary N, Troiani L, Chopra M, Markovic-Plese S.
|
| J Immunol 186(7):4518-26. Epub 2011 Mar 2.
2011
|
| 31 | IFNB1
|
| Interferon-beta is a key regulator of proinflammatory events in experimental autoimmune encephalomyelitis.
|
| Galligan CL, Pennell LM, Murooka TT, Baig E, Majchrzak-Kita B, Rahbar R, Fish EN.
|
| Mult Scler 16(12):1458-73. Epub 2010 Oct 8.
2010
|
| 32 | IFNB1
|
| Increased caspase-2 activity is associated with induction of apoptosis in IFN-beta sensitive melanoma cell lines.
|
| Kamiya T, Okabayashi T, Yokota S, Kan Y, Ogino J, Yamashita T, Fujii N, Jimbow K.
|
| J Interferon Cytokine Res 30(5):349-57.
2010
|
| 33 | IFNB1
|
| Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70.
|
| Zietara N, Łyszkiewicz M, Gekara N, Puchałka J, Dos Santos VA, Hunt CR, Pandita TK, Lienenklaus S, Weiss S.
|
| J Immunol 183(2):1099-109.
2009
|
| 34 | IFNB1
|
| Interferon-beta modulates protein synthesis in the central nervous system.
|
| Beyer S, Raether G, Stadler K, Hoffrogge R, Scharf C, Rolfs A, Mix E, Strauss U.
|
| J Neuroimmunol 213(1-2):31-8. Epub 2009 Jul 9.
2009
|
| 35 | IFNB1
|
| Interferon-beta augments eosinophil adhesion-inducing activity of endothelial cells.
|
| Kobayashi T, Takaku Y, Yokote A, Miyazawa H, Soma T, Hagiwara K, Kanazawa M, Nagata M.
|
| Eur Respir J 32(6):1540-7. Epub 2008 Jul 24.
2008
|
| 36 | IFNB1
|
| Type I interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis.
|
| Walsh RJ, Kong SW, Yao Y, Jallal B, Kiener PA, Pinkus JL, Beggs AH, Amato AA, Greenberg SA.
|
| Arthritis Rheum 56(11):3784-92. 2007
|
| 37 | IFNB1
|
| Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells.
|
| Hu J, Sealfon SC, Hayot F, Jayaprakash C, Kumar M, Pendleton AC, Ganee A, Fernandez-Sesma A, Moran TM, Wetmur JG.
|
| Nucleic Acids Res 35(15):5232-41. Epub 2007 Aug 2. 2007
|
| 38 | IFNB1
|
| IFN-beta inhibits T cell activation capacity of central nervous system APCs.
|
| Teige I, Liu Y, Issazadeh-Navikas S.
|
| J Immunol 177(6):3542-53. 2006
|
| 39 | IFN1@, IFNB1, IFNG, IFNP11, IFNP12, IFNW1, IFNWP2, IFNWP5, IFNWP9, IFNWP15, IFNWP18, IFNWP19, IFNP20, IFNP23, IFNP24
|
| Structure of the human type-I interferon gene cluster determined from a YAC clone contig.
|
| Diaz MO, et al.
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| Genomics 22 : 540-552. 1994
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| 40 | IFNB1, D9S126
|
| Genetic and physical map of the interferon region on chromosome 9p.
|
| Fountain JW, et al.
|
| Genomics 14 : 105-112. 1992
|
| 41 | IFNB1
|
| Polymerase chain reaction based assay to detect allelic loss in human DNA : loss of beta-interferon gene in chronic myelogeneous leukemia.
|
| Neubauer A, et al.
|
| Nucleic Acids Res 18 : 993-998. 1990
|
| 42 | ETS1, IFN1@, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA16, IFNA17, IFNA21, IFNAP22, IFNB1
|
| Interferon and c-ets-1 genes in the translocation (9:11)(p22:q23) in human acute monocytic leukemia.
|
| Diaz MO, et al.
|
| Science 231 : 265-267. 1986
|
| 43 | IFN1@, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA16, IFNA17, IFNA21, IFNAP22, IFNB1
|
| Close linkage of alpha and beta interferons and infrequent duplication of beta interferon in humans.
|
| Ohlsson M, et al.
|
| Proc Natl Acad Sci U S A 82 : 4473-4476. 1985
|
| 44 | IFN1@, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA16, IFNA17, IFNA21, IFNAP22, IFNB1
|
| Clustering of leukocyte and fibroblast interferon genes on human chromosome 9.
|
| Shows TB, Sakaguchi AY, Naylor SL, Goedell DV, Lawn RM.
|
| Science 218 : 373-374. 1982
|
| 45 | IFN1@, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA16, IFNA17, IFNA21, IFNAP22, IFNB1
|
| Both leucocyte (IFL) and fibroblast (IFF) interferon genes are on chromosome 9.
|
| Owerbach D, et al.
|
| Cytogenet Cell Genet 32 : 307. 1982
|
| 46 | IFNB1, IL6, IFNB3
|
| Multiple human beta interferon genes.
|
| Sagar AD, Sehgal PB, Slate DL, Ruddle FH.
|
| J Exp Med 156(3):744-55. 1982
|
| 47 | IFN1@, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA16, IFNA17, IFNA21, IFNAP22, IFNB1, IFNG
|
| Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization.
|
| Trent JM, et al.
|
| Proc Natl Acad Sci U S A 79 : 7809-7813. 1982
|
| 48 | IFNB1, IFNB3
|
| Fibrolast interferon in man is coded by two loci on separate chromosomes.
|
| Slate DL, et al.
|
| Cell 16 : 171-180. 1979
|
| 49 | IFNB1
|
| Tentative assignment of the gene for human fibroblast interferon to chromosome 9.
|
| Meager A, et al.
|
| Cytogenet Cell Genet 25 : 183-184. 1979
|
| 50 | IFNAR1, IFNAR2, IFNB1
|
| 208.
|
| Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1.
|
| de Weerd NA, Vivian JP, Nguyen TK, Mangan NE, Gould JA, Braniff SJ, Zaker-Tabrizi L, Fung KY, Forster SC, Beddoe T, Reid HH, Ros e Weerd NA, Vivian JP, Nguyen TK, Mangan NE, Gould JA, Braniff SJ, Zaker-Tabrizi L, Fung KY, Forster SC, Beddoe T, Reid HH, Ross
|