| 1 | EIF2AK3, IFNAR1
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| Type I interferons mediate pancreatic toxicities of PERK inhibition.
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| Yu Q, Zhao B, Gui J, Katlinski KV, Brice A, Gao Y, Li C, Kushner JA, Koumenis C, Diehl JA, Fuchs SY.
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| Proc Natl Acad Sci U S A 112(50):15420-5. doi: 10.1073/pnas.1516362112. Epub 2015 Dec 1.
2015
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| 2 | IFNAR1, ZG16B
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| Pancreatic adenocarcinoma upregulated factor (PAUF) confers resistance to pancreatic cancer cells against oncolytic parvovirus H-1 infection through IFNA receptor-mediated signaling.
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| Kaowinn S, Cho IR, Moon J, Jun SW, Kim CS, Kang HY, Kim M, Koh SS, Chung YH.
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| Biochem Biophys Res Commun 459(2):313-8. doi: 10.1016/j.bbrc.2015.02.107. Epub 2015 Feb 26.
2015
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| 3 | IFNAR1, TYK2
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| Structural basis of recognition of interferon-α receptor by tyrosine kinase 2.
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| Wallweber HJ, Tam C, Franke Y, Starovasnik MA, Lupardus PJ.
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| Nat Struct Mol Biol 21(5):443-8. doi: 10.1038/nsmb.2807. Epub 2014 Apr 6.
2014
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| 4 | IFNAR1, PTPN1
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| Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies.
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| Carbone CJ, Zheng H, Bhattacharya S, Lewis JR, Reiter AM, Henthorn P, Zhang ZY, Baker DP, Ukkiramapandian R, Bence KK, Fuchs SY.
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| Proc Natl Acad Sci U S A 109(47):19226-31. doi: 10.1073/pnas.1211491109. Epub 2012 Nov 5.
2012
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| 5 | IFNAR1, PRKD2
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| Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2.
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| Zheng H, Qian J, Varghese B, Baker DP, Fuchs S.
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| Mol Cell Biol 31(4):710-20. doi: 10.1128/MCB.01154-10. Epub 2010 Dec 20.
2011
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| 6 | IFNAR1
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| Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor.
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| Bhattacharya S, HuangFu WC, Liu J, Veeranki S, Baker DP, Koumenis C, Diehl JA, Fuchs SY.
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| J Biol Chem 285(4):2318-25. Epub 2009 Nov 30.
2010
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| 7 | IFNAR1, IFNAR2
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| Biochemical monitoring of the early endocytic traffic of the type I interferon receptor.
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| Payelle-Brogard B, Pellegrini S.
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| J Interferon Cytokine Res 30(2):89-98.
2010
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| 8 | IFNAR1
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| Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.
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| Claudinon J, Gonnord P, Beslard E, Marchetti M, Mitchell K, Boularan C, Johannes L, Eid P, Lamaze C.
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| J Biol Chem 284(36):24328-40. Epub 2009 Jun 26.
2009
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| 9 | IFNAR1
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| Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection.
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| Zhou J, Huang JD, Poon VK, Chen DQ, Chan CC, Ng F, Guan XY, Watt RM, Lu L, Yuen KY, Zheng BJ.
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| J Hepatol 51(2):322-32. Epub 2009 May 3.
2009
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| 10 | IFNAR1
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| A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection.
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| Zhou J, Smith DK, Lu L, Poon VK, Ng F, Chen DQ, Huang JD, Yuen KY, Cao KY, Zheng BJ.
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| J Viral Hepat 16(1):45-52. Epub 2008 Aug 28.
2009
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| 11 | IFNAR1, IFNAR2
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| IFNAR1 and IFNAR2 polymorphisms in patients with Behçet's disease.
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| Pay S, Musabak U, Cobankara V, Sagkan RI, Simsek I, Keskin F, Erdem H, Kose O, Dinc A.
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| Clin Exp Rheumatol 27(2 Suppl 53):S110-1. No abstract available.
2009
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| 12 | IFNAR1, IFNAR2
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| Modulation of IFNAR1 mRNA expression in multiple sclerosis patients.
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| Serana F, Sottini A, Ghidini C, Zanotti C, Capra R, Cordioli C, Caimi L, Imberti L.
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| J Neuroimmunol 197(1):54-62. Epub 2008 May 15.
2008
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| 13 | IFNAR1, TRAF2
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| The role of TRAF2 binding to the type I interferon receptor in alternative NF kappaB activation and antiviral response.
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| Yang CH, Murti A, Pfeffer SR, Fan M, Du Z, Pfeffer LM.
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| J Biol Chem 283(21):14309-16. Epub 2008 Mar 24. Erratum in: J Biol Chem. 2008 Dec 26;283(52):36752.
2008
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| 14 | IFNAR1
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| Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis.
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| Kumar KG, Barriere H, Carbone CJ, Liu J, Swaminathan G, Xu P, Li Y, Baker DP, Peng J, Lukacs GL, Fuchs SY.
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| J Cell Biol 179(5):935-50.
2007
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| 15 | IFNAR1, IFNAR2
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| A structural basis for interferon-alpha-receptor interactions.
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| Kumaran J, Wei L, Kotra LP, Fish EN.
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| FASEB J 21(12):3288-96. Epub 2007 May 21.
2007
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| 16 | IFNAR1, IFNAR2
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| Increased interferon alpha receptor 2 mRNA levels is associated with renal cell carcinoma metastasis.
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| Kamai T, Yanai Y, Arai K, Abe H, Yamanishi T, Kurimoto M, Yoshida K.
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| BMC Cancer 7:159.
2007
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| 17 | IFNR, IFNAR1, TYK2
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| TYK2 activity promotes ligand-induced IFNAR1 proteolysis.
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| Marijanovic Z, Ragimbeau J, Kumar KG, Fuchs SY, Pellegrini S.
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| Biochem J 397(1):31-8. 2006
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| 18 | IFNAR1, IFNAR2, TMEM50B
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| Sequence analysis of the porcine IFNAR1 and IFNGR2 genes.
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| Leeb T, Dolle K, Haase B.
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| Cytogenet Genome Res 115(2):134-7. 2006
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| 19 | IFNAR1, IRF5, TYK2
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| Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
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| Sigurdsson S, Nordmark G, Goring HH, Lindroos K, Wiman AC, Sturfelt G, Jonsen A, Rantapaa-Dahlqvist S, Moller B, Kere J, Koskenmies S, Widen E, Eloranta ML, Julkunen H, Kristjansdottir H, Steinsson K, Alm G, Ronnblom L, Syvanen AC.
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| Am J Hum Genet 76(3):528-37. Epub 2005 Jan 18. 2005
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| 20 | IFNAR1
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| The IFNAR1 subunit of the type I IFN receptor complex contains a functional nuclear localization sequence.
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| Subramaniam PS, Johnson HM.
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| FEBS Lett 578(3):207-10. 2004
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| 21 | TMEM50B, IL10RB, IFNAR1, IFNAR2, IFNGR2
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| Comparative genomic analysis of the Interferon/Interleukin-10 receptor gene cluster.
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| Reboul J, et al.
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| Genome Res 9(3):242-50. 1999
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| 22 | IL10RB, GART, IFNAR1, IFNAR2
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| Characterization of four yeast artificial chromosome clones mapped to human chromosome 21q22.1 with eight markers.
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| Kim MY, Kwon HB, Soh J.
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| Mol Cell 7(4):526-31. 1997
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| 23 | IFNAR1, IFNAR2
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| Mapping of genes encoding type 1 interferon receptors and signalling molecules to human chromosome 21 and studies on their function. (abstr)
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| Hertzog PJ, et al.
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| Cytogenet Cell Genet 79 : 43. 1997
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| 24 | IFNAR1, IFNAR2, IFNGR2
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| Three distinct loci on human chromosome 21 contribute to interferon-alpha/beta responsiveness.
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| Raz R, et al.
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| Somat Cell Mol Genet 21 : 139-145. 1995
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| 25 | IL10RB, IFNAR1, IFNAR2, IFNGR2
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| Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster.
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| Lutfalla G, et al.
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| EMBO J 14 : 101-109. 1995
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| 26 | IFNAR1
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| Transmembrane signaling by the alpha subunit of the type I interferon receptor is essential for activation of the jak kinase and the transcriptional factor ISGF3.
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| Colamonici OR, et al.
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| J Biol Chem 270 : 8188-8193. 1995
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| 27 | IFNAR1
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| Knockout and reconstitution of a functional human type I interferon receptor complex.
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| Cleary CM, et al.
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| J Biol Chem 269 : 18747-18749. 1994
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| 28 | IFNAR1
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| Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor.
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| Colamonici OR, et al.
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| J Biol Chem 269 : 27275-27279. 1994
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| 29 | IFNAR1
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| Linkage mapping of highly informative DNA polymorphisms within the humaninterferon-alpha receptor gene on chromosome 21.
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| McInnis MG, et al.
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| Genomics 11 : 573-576. 1991
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| 30 | IFNAR1
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| Assignment of the human interferon-alpha receptor gene to chromosome 21q22.1 by in situ hybridization.
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| Lutfalla G, et al.
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| J Interferon Res 10 : 515-517. 1990
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| 31 | IFNAR1
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| HindIII RFLP at the human IFNAR locus.
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| Vielh E, et al.
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| Nucleic Acids Res 18 : 5580. 1990
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| 32 | IFNAR1
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| Genetic transfer of a functional human interferon alpha receptor into mouse cells : cloning and expression of its cDNA.
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| Uz G, et al.
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| Cell 60 : 225-234. 1990
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| 33 | IFNAR1, IFNAR2, IFNGR1
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| The gene for the human immune interferon receptor is located on chromosome 6.
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| Rashidbaigi A, et al.
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| Proc Natl Acad Sci U S A 83 : 384-388. 1986
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| 34 | IFNAR1, IFNAR2
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| Enhanced expression of cellular receptors for human interferon alpha on peripheral lymphocytes from patients with Down's syndrome.
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| Mogensen KE, et al.
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| FEBS Lett 140 : 285-287. 1982
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| 35 | B2MR, IFNAR1, IFNAR2
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| High-resolution analysis of chromosome markers in Burkitt lymphoma cell lines.
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| Zhang S, et al.
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| Int J Cancer 29 : 153-157. 1982
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| 36 | IFNAR1, IFNAR2
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| Chromosomal localization of human genes governing the interferon-induced anti-viral state.
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| Chany C, et al.
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| Proc Natl Acad Sci U S A 72 : 3129-3133. 1975
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| 37 | IFNAR1, IFNAR2, SOD1
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| The linkage of genes for the human interferon-induces antiviral protein and indophenol oxidase-B traits to chromosome G-21.
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| Tan YH, et al.
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| J Exp Med 137 : 317-330. 1973
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| 38 | IFNAR1, IFNAR2, IFNB1
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| 208.
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| Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1.
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| de Weerd NA, Vivian JP, Nguyen TK, Mangan NE, Gould JA, Braniff SJ, Zaker-Tabrizi L, Fung KY, Forster SC, Beddoe T, Reid HH, Ros e Weerd NA, Vivian JP, Nguyen TK, Mangan NE, Gould JA, Braniff SJ, Zaker-Tabrizi L, Fung KY, Forster SC, Beddoe T, Reid HH, Ross
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