Citations for
1ID4, MMP2
Id4 suppresses MMP2-mediated invasion of glioblastoma-derived cells by direct inactivation of Twist1 function.
Rahme GJ, Israel MA.
Oncogene ncogene. 2014 Jan 13. doi: 10.1038/onc.2013.531. [Epub ahead of print] 2014
2ID1, ID2, ID3, ID4, ZBTB18
RP58 controls neuron and astrocyte differentiation by downregulating the expression of Id1-4 genes in the developing cortex.
Hirai S, Miwa A, Ohtaka-Maruyama C, Kasai M, Okabe S, Hata Y, Okado H.
EMBO J 31(5):1190-202. doi: 10.1038/emboj.2011.486. Epub 2012 Jan 10. 2012
3ID2, ID4, PRMT5
Type II arginine methyltransferase PRMT5 regulates gene expression of inhibitors of differentiation/DNA binding Id2 and Id4 during glial cell differentiation.
Huang J, Vogel G, Yu Z, Almazan G, Richard S.
J Biol Chem 286(52):44424-32. doi: 10.1074/jbc.M111.277046. Epub 2011 Oct 31. 2011
4HES1, HES2, ID4, RUNX2
Id4, a new candidate gene for senile osteoporosis, acts as a molecular switch promoting osteoblast differentiation.
Tokuzawa Y, Yagi K, Yamashita Y, Nakachi Y, Nikaido I, Bono H, Ninomiya Y, Kanesaki-Yatsuka Y, Akita M, Motegi H, Wakana S, Noda T, Sablitzky F, Arai S, Kurokawa R, Fukuda T, Katagiri T, Schönbach C, Suda T, Mizuno Y, Okazaki Y.
PLoS Genet 6(7):e1001019.PMID: 20628571 2010
5ID4
ID4 methylation predicts high risk of leukemic transformation in patients with myelodysplastic syndrome.
Wang H, Wang XQ, Xu XP, Lin GW.
Leuk Res 34(5):598-604. Epub 2009 Oct 23.PMID: 19853913 2010
6ID4
The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.
Fontemaggi G, Dell'Orso S, Trisciuoglio D, Shay T, Melucci E, Fazi F, Terrenato I, Mottolese M, Muti P, Domany E, Del Bufalo D, Strano S, Blandino G.
Nat Struct Mol Biol 16(10):1086-93. Epub 2009 Sep 27.PMID: 19783986 2009
7ID4
Differential methylation pattern of ID4, SFRP1, and SHP1 between acute myeloid leukemia and chronic myeloid leukemia.
Uhm KO, Lee ES, Lee YM, Park JS, Kim SJ, Kim BS, Kim HS, Park SH.
J Korean Med Sci 24(3):493-7. Epub 2009 Jun 18.PMID: 19543515 2009
8ID4
Cdc42 is highly expressed in colorectal adenocarcinoma and downregulates ID4 through an epigenetic mechanism.
Gómez Del Pulgar T, Valdés-Mora F, Bandrés E, Pérez-Palacios R, Espina C, Cejas P, García-Cabezas MA, Nistal M, Casado E, González-Barón M, García-Foncillas J, Lacal JC.
Int J Oncol 33(1):185-93.PMID: 18575765 2008
9ID4
Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer.
Noetzel E, Veeck J, Niederacher D, Galm O, Horn F, Hartmann A, Knüchel R, Dahl E.
BMC Cancer 8:154.PMID: 18513385 2008
10ID4
Frequent DNA methylation but not mutation of the ID4 gene in malignant lymphoma.
Hagiwara K, Nagai H, Li Y, Ohashi H, Hotta T, Saito H.
J Clin Exp Hematop 47(1):15-8.PMID: 17510533 2007
11MECP2, ID1, ID2, ID3, ID4
Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome.
Peddada S, Yasui DH, LaSalle JM.
Hum Mol Genet 15(12):2003-14. Epub 2006 May 8. 2006
12ID4
Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia.
Yu L, Liu C, Vandeusen J, Becknell B, Dai Z, Wu YZ, Raval A, Liu TH, Ding W, Mao C, Liu S, Smith LT, Lee S, Rassenti L, Marcucci G, Byrd J, Caligiuri MA, Plass C.
Nat Genet 37(3):265-74. Epub 2005 Feb 20. 2005
13ID4
Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer.
Umetani N, Mori T, Koyanagi K, Shinozaki M, Kim J, Giuliano AE, Hoon DS.
Oncogene 24(29):4721-7. 2005
14ID4, STC1
BRCA1 transcriptionally regulates genes involved in breast tumorigenesis.
Welcsh PL, Lee MK, Gonzalez-Hernandez RM, Black DJ, Mahadevappa M, Swisher EM, Warrington JA, King MC.
Proc Natl Acad Sci U S A 99(11):7560-5. 2002
15ID4
cDNA cloning, tissue distribution and chromosomal localization of the human ID4 gene.
Rigolet M, Rich T, Gross-Morand MS, Molina-Gomes D, Viegas-Pequignot E, Junien C.
DNA Res 5(5):309-13 1998
16ID4
Molecular cloning of ID4, a novel dominant negative helix-loop-helix human gene on chromosome 6p21.3-p22.
Pagliuca A, et al.
Genomics 27 : 200-203. 1995
17ID1, ID2, ID3, ID4
The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3.
R•echmann V, et al.
Nucleic Acids Res 22 : 749-755. 1994