Citations for
1ID1, ID3
Combined Id1 and Id3 Deletion Leads to Severe Erythropoietic Disturbances.
Zhao Q, Chang C, Gonzalez JP, Alzahrani K, Button JL, Fraidenraich D.
PLoS One 11(4):e0154480. doi: 10.1371/journal.pone.0154480. eCollection 2016. 2016
2ID1, ID2, ID3, ID4, ZBTB18
RP58 controls neuron and astrocyte differentiation by downregulating the expression of Id1-4 genes in the developing cortex.
Hirai S, Miwa A, Ohtaka-Maruyama C, Kasai M, Okabe S, Hata Y, Okado H.
EMBO J 31(5):1190-202. doi: 10.1038/emboj.2011.486. Epub 2012 Jan 10. 2012
3ID1, LARP6
Acheron regulates vascular endothelial proliferation and angiogenesis together with Id1 during wound healing.
Sun R, Chen W, Zhao X, Li T, Song Q.
Cell Biochem Funct 29(8):636-40. doi: 10.1002/cbf.1799. Epub 2011 Aug 23. 2011
4ID1, ID3, SMURF2
Smurf2-mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence.
Kong Y, Cui H, Zhang H.
Aging Cell 10(6):1038-46. doi: 10.1111/j.1474-9726.2011.00746.x. Epub 2011 Oct 7. 2011
5ID1, ID3
ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis.
Hong SH, Lee JH, Lee JB, Ji J, Bhatia M.
J Cell Sci 124(Pt 9):1445-52. Epub 2011 Apr 12. 2011
6ID1, PRKCA
Protein kinase Cα signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium.
Hao F, Pysz MA, Curry KJ, Haas KN, Seedhouse SJ, Black AR, Black JD.
J Biol Chem 286(20):18104-17. doi: 10.1074/jbc.M110.208488. Epub 2011 Mar 18. 2011
7ID1, RNF2
Id1 enhances RING1b E3 ubiquitin ligase activity through the Mel-18/Bmi-1 polycomb group complex.
Qian T, Lee JY, Park JH, Kim HJ, Kong G.
Oncogene 29(43):5818-27. Epub 2010 Aug 9. 2010
8ID1, NR1D1
Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction.
Phelan CA, Gampe RT Jr, Lambert MH, Parks DJ, Montana V, Bynum J, Broderick TM, Hu X, Williams SP, Nolte RT, Lazar MA.
Nat Struct Mol Biol 17(7):808-14. Epub 2010 Jun 27. 2010
9ID1, ID3
Targeting Id1 and Id3 by a specific peptide aptamer induces E-box promoter activity, cell cycle arrest, and apoptosis in breast cancer cells.
Mern DS, Hoppe-Seyler K, Hoppe-Seyler F, Hasskarl J, Burwinkel B.
Breast Cancer Res Treat 124(3):623-33. Epub 2010 Feb 27. 2010
10ID1
Inhibitor of DNA binding-1 overexpression in prostate cancer: relevance to tumor differentiation.
Yu X, Xu X, Han B, Zhou R.
Pathol Oncol Res 15(1):91-6. Epub 2008 Aug 28. 2009
11ID1
Id-1 expression in androgen-dependent prostate cancer is negatively regulated by androgen through androgen receptor.
Xu B, Sun Y, Tang G, Xu C, Wang L, Zhang Y, Ji J.
Cancer Lett 278(2):220-9. Epub 2009 Feb 7. 2009
12ID1
Bone marrow and peripheral blood expression of ID1 in human gastric carcinoma patients is a bona fide indicator of lymph node and peritoneal metastasis.
Iwatsuki M, Fukagawa T, Mimori K, Nakanishi H, Ito S, Ishii H, Yokobori T, Sasako M, Baba H, Mori M.
Br J Cancer 100(12):1937-42. Epub 2009 Jun 2. 2009
13ID1
Smad3 mediates immediate early induction of Id1 by TGF-beta.
Liang YY, Brunicardi FC, Lin X.
Cell Res 19(1):140-8. 2009
14DTX1, ID1
Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression.
Wang HC, Perry SS, Sun XH.
Mol Cell Biol 29(17):4640-52. Epub 2009 Jun 29. 2009
15ID1
ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling.
Wood AD, Chen E, Donaldson IJ, Hattangadi S, Burke KA, Dawson MA, Miranda-Saavedra D, Lodish HF, Green AR, Göttgens B.
Blood 114(9):1820-30. Epub 2009 Jul 1. 2009
16ID1
Identification of a novel estrogen receptor beta1 binding partner, inhibitor of differentiation-1, and role of ERbeta1 in human breast cancer cells.
Chen L, Qiu J, Yang C, Yang X, Chen X, Jiang J, Luo X.
Cancer Lett 278(2):210-9. Epub 2009 Feb 13. 2009
17ID1, ID2, ITF2
Expression of Id and ITF-2 genes in the mammary gland during pregnancy.
Itahana Y, Piens M, Fong S, Singh J, Sumida T, Desprez PY.
Biochem Biophys Res Commun 372(4):826-30. Epub 2008 Jun 2. 2008
18ARID3A, ID1
Cross talk between Id1 and its interactive protein Dril1 mediate fibroblast responses to transforming growth factor-beta in pulmonary fibrosis.
Lin L, Zhou Z, Zheng L, Alber S, Watkins S, Ray P, Kaminski N, Zhang Y, Morse D.
Am J Pathol 173(2):337-46. Epub 2008 Jun 26. 2008
19ID1
ID genes mediate tumor reinitiation during breast cancer lung metastasis.
Gupta GP, Perk J, Acharyya S, de Candia P, Mittal V, Todorova-Manova K, Gerald WL, Brogi E, Benezra R, MassaguŽ J.
Proc Natl Acad Sci U S A 104(49):19506-11. Epub 2007 Nov 28. 2007
20ZBTB16, TP53INP1, TERT, ID3, ID1
Identification of apoptosis-related PLZF target genes.
Bernardo MV, Yelo E, Gimeno L, Campillo JA, Parrado A.
Biochem Biophys Res Commun 359(2):317-22. Epub 2007 May 24. 2007
21CEBPA, ID1
Absence of the transcription factor CCAAT enhancer binding protein {alpha} results in loss of myeloid identity in bcr/abl-induced malignancy.
Wagner K, Zhang P, Rosenbauer F, Drescher B, Kobayashi S, Radomska HS, Kutok JL, Gilliland DG, Krauter J, Tenen DG.
Proc Natl Acad Sci U S A 103(16):6338-43. Epub 2006 Apr 10. 2006
22MECP2, ID1, ID2, ID3, ID4
Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome.
Peddada S, Yasui DH, LaSalle JM.
Hum Mol Genet 15(12):2003-14. Epub 2006 May 8. 2006
23ID1, ID3
Id proteins negatively regulate basic helix-loop-helix transcription factor function by disrupting subnuclear compartmentalization.
O'Toole PJ, Inoue T, Emerson L, Morrison IE, Mackie AR, Cherry RJ, Norton JD.
J Biol Chem 278(46):45770-6. Epub 2003 Sep 1. 2003
24ID1
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter.
Korchynskyi O, ten Dijke P.
J Biol Chem 277(7):4883-91. 2002
25ID1
Constitutive expression of the Id-1 promoter in human metastatic breast cancer cells is linked with the loss of NF-1/Rb/HDAC-1 transcription repressor complex.
Singh J, Murata K, Itahana Y, Desprez PY.
Oncogene 21(12):1812-22. 2002
26ID1
Id-1 stimulates serum independent prostate cancer cell proliferation through inactivation of p16(INK4a)/pRB pathway.
Ouyang XS, Wang X, Ling MT, Wong HL, Tsao SW, Wong YC.
Carcinogenesis 23(5):721-5. 2002
27ID1
Down-regulation of Id-1 expression is associated with TGF beta 1-induced growth arrest in prostate epithelial cells.
Ling MT, Wang X, Tsao SW, Wong YC.
Biochim Biophys Acta 1570(3):145-52. 2002
28CDKN2A, ID1
The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas.
Polsky D, Young AZ, Busam KJ, Alani RM.
Cancer Res 61(16):6008-11. 2001
29ID1, ARFGAP2
Molecular cloning and characterization of a zinc finger protein involved in Id-1-stimulated mammary epithelial cell growth.
Singh J, Itahana Y, Parrinello S, Murata K, Desprez PY.
J Biol Chem 276(15):11852-8. 2001
30CDKN2A, ETS1, ETS2, ID1
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence.
Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, Ohashi Y, Sharrocks AD, Peters G, Hara E.
Nature 409(6823):1067-70. 2001
31ID1, ID3
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts.
Lyden D, et al.
Nature 401(6754):670-7 1999
32ID1
Genomic organization, sequence, and chromosomal localization of the human helix-loop-helix Id1 gene.
Nehlin JO, et al.
Biochem Biophys Res Commun 231 : 628-634. 1997
33ID1, ID2
Chromosomal assignment of human ID1 and ID2 genes.
Mathew S, et al.
Genomics 30 : 385-387. 1995
34ID1
Id gene expression during development and molecular cloning of the human Id-1 gene.
Zhu W, Dahmen J, Bulfone A, Rigolet M, Hernandez MC, Kuo WL, Puelles L, Rubenstein JL, Israel MA.
Brain Res Mol Brain Res 30(2):312-26. 1995
35ID1, ID2, ID3, ID4
The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3.
R•echmann V, et al.
Nucleic Acids Res 22 : 749-755. 1994
36ID1
Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts.
Hara E, Yamaguchi T, Nojima H, Ide T, Campisi J, Okayama H, Oda K.
J Biol Chem 269(3):2139-45. 1994
37ID1, ID2
Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins.
Sun XH, et al.
Mol Cell Biol 11 : 5603-5611. 1991